Support by accredited stakeholders
This page offers web links to tools, information and guidance that are publically available and free of charge. They have been provided by ECHA's accredited stakeholders, and are published with the aim to facilitate the implementation of European chemicals legislation.
Linking to other websites should not be taken as an endorsement of any kind by ECHA. If you access another site through one of these links you are subject to the privacy policy of that site. For further information see ECHA's Legal Notice.
- REACH implementation and communication support
- REACH guidance and support for the automotive industry
- Implementing REACH
- Use descriptors, risk management measures and specific environmental release categories
- Support for the substitution of hazardous chemicals
- Information for the petroleum industry
- Tool for worker exposure assessment models
- REACH support
- Tools for REACH requirements in plant protection
- Supporting communication in the supply chain
- Information for ferro-alloys and silicon producers
- REACH information, helpdesk and data sharing forum
- REACH and CLP support
- Tool to predict indoor aerosol concentration
- Safety, Health and Environment Committee
- Use descriptors
- Nano safety assessment projects
- Webinars on inhalation toxicity testing
- Description:
- One focus area for the Science Consortium is developing effective and efficient approaches to assess inhalation toxicity that protects human health without using animals. This webinar series presents non-animal approaches for inhalation toxicity testing and covers In Silico models, In Vitro systems and Integrated Approaches to Testing and Assessment (IATAs)
- Webinar 1: Perspectives on the Development, Evaluation, and Application of in Silico Approaches for Predicting Toxicity
- Date:
- 25 January 2018
- Speakers:
- Dr. Grace Patlewicz, U.S. EPA
Professor Mark Cronin, Liverpool John Moores University - Description:
- Dr Patlewicz and Professor Cronin discuss the QSARs that can be used to meet regulatory testing requirements under REACH. The use of read-across is presented – emphasising both the availability of different frameworks for the development of read-across and frameworks for the assessment and evaluation of read-across justification – highlighting examples published in the literature as well as regulatory technical guidance (OECD, ECHA). Tools that can help facilitate the development of read-across, including the OECD QSAR Toolbox, are outlined. Attention is drawn to ongoing research that is evolving the way in which read-across approaches can be undertaken, including by exploiting the use of high-throughput screening data such as those generated under the US EPA's ToxCast programme. The use of read-across and QSARs is framed in the context of integrated approaches to testing and assessment (IATA). Examples highlight how some IATA have evolved, particularly in the arena of skin sensitisation, where defined approaches have been developed. These formalise the use of certain non-animal test methods that characterise the key events within the associated adverse outcome pathway.
- Webinar 2: Skin irritation and corrosion
- Date:
- 1 February 2018
- Speakers:
- Dr. Gertrude-Emilia Costin, Institute for In Vitro Sciences
Dr. Costanza Rovida, TEAM Mastery and CAAT Europe - Description:
- Dr. Costin will describe the in vitro methods that can be used to meet REACH data requirements for skin irritation and corrosion under Annexes VII and VIII. Dr. Rovida will use specific examples to explain how the in vitro methods can be used in an integrated approach to testing and assessment.
- Webinar 3: Eye irritation and Corrosion
- Date:
- 15 February 2018
- Speakers:
- Dr. Kim Norman, Burt's Bees
Dr. Els Adriaens, Ghent University - Description:
- Drs. Norman and Dr. Adriaens will first discuss the drivers of in vivo classification for serious eye damage and eye irritation in order to specify the requirements for achieving full replacement of the regulatory animal test. They will then describe the available in vitro methods and the ways in which they can be used alone or in combination in various testing strategies, such as top-down or bottom-up approaches.
- Webinar 4: 3R approach to acute oral toxicity
- Date:
- 19 December 2017
- Speakers:
- Dr Kimmo Louekari, ECHA
- Description:
- Dr. Louekari presents on 3R approaches to acute oral toxicity testing. He describes an approach that includes waiving such testing when subacute oral toxicity data indicate low toxicity and an enhanced dose-range finding study, or in vitro 3T3 neutral red uptake cytotoxicity test, are provided in the context of the weight-of-evidence approach.
- Archive of 2014-2015 webinar series
- Description:
- The PETA International Science Consortium and Chemical Watch, a global regulatory news and information service for the chemical industry, have teamed up to present a free webinar series focusing on non-animal methods and testing strategies that can be used to meet REACH requirements. The webinars will be of interest to industry toxicologists, those registering chemicals for the first time, companies that would like to know more about the validated non-animal tests that are available and the ways other businesses are using them, and REACH consultants.
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