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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol 938-572-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
22/10/2018
22/10/2018
2-(2-thienyl)ethyl toluene-p-sulphonate 254-911-5 40412-06-4 Genetic toxicity in vivo 06/09/2018 22/10/2018
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018
5-Methoxy-2-tetralone 457-080-9 - Genetic toxicity in vivo 06/09/2018 22/10/2018
Polysulfides, di-tert-nonyl 270-336-2 68425-16-1 Sub-chronic toxicity (90-day): oral 06/09/2018 22/10/2018
Soybean oil, oligomerized 701-252-0 - Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 213-485-0 957-68-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
10/08/2018
10/08/2018
10/08/2018
24/09/2018
24/09/2018
24/09/2018
Allyl (cyclohexyloxy)acetate 272-657-3 68901-15-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
24/09/2018
24/09/2018
1-chloro-2,3-dimethylbenzene 480-880-4 608-23-1 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters 701-257-8 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5) 10/08/2018 24/09/2018
Oxydipropyl dibenzoate 248-258-5 27138-31-4 Long-term toxicity to fish 10/08/2018 24/09/2018
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated 812-927-5 1902936-62-2 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) 916-899-6 - Sub-chronic toxicity (90-day): oral 10/08/2018 24/09/2018
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 10/08/2018 24/09/2018
Zinc bis(diethyldithiocarbamate) 238-270-9 14324-55-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 10/08/2018 24/09/2018
Ethane- 1,2-diol, propoxylated 500-078-0 31923-84-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Propylidynetrimethanol, propoxylated 500-041-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
2,2'-azobis[2-methylpropionamidine] dihydrochloride 221-070-0 2997-92-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Nonane-1,9-diol 223-517-5 3937-56-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Tetra(isobutyl)thioperoxydicarbamic acid 221-312-5 3064-73-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/06/2018
18/06/2018
02/08/2018
02/08/2018
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018
Bumetrizole 223-445-4 3896-11-5 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
Dipotassium tetrachloroplatinate 233-050-9 10025-99-7 Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." 18/06/2018 02/08/2018
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/06/2018 02/08/2018
Zinc, bis[O,O-bis(1-methylethyl) phosphorodithioato-.kappa.S]bis(cyclohexanamine)-, (T-4)- 809-986-4 52585-16-7 Genetic toxicity in vivo 18/06/2018 02/08/2018
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen 701-207-5 1950616-36-0
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Ethylene dibenzoate 202-338-6 94-49-5
Reproductive toxicity (pre-natal developmental toxicity 
Developmental neurotoxicity
21/05/2018
21/05/2018
05/07/2018
05/07/2018
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine 447-920-2 - Reproductive toxicity (pre-natal developmental toxicity) 21/05/2018 05/07/2018
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Dihexadecyl peroxodicarbonate 247-611-0 26322-14-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
N-methylaniline 202-870-9 100-61-8
Sub-chronic toxicity (90 day): dermal
Reproductive toxicity (extended one-generation reproductive toxicity study)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Triethoxy(vinyl)silane 201-081-7 78-08-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Alcohols, C18-22, distn. residues 641-136-6 1160164-88-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) 931-276-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Reproductive toxicity (extended one-generation reproductive toxicity study 23/04/2018 07/06/2018
Hexadecyldimethylamine 695-101-5 1275611-65-8 Reproductive toxicity (pre-natal developmental toxicity) 23/04/2018 07/06/2018
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs 931-371-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) 23/04/2018 07/06/2018
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
2,4,4-trimethylpentene 246-690-9 25167-70-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
26/03/2018
26/03/2018
11/05/2018
11/05/2018
2-methylpentane-2,4-diol 203-489-0 107-41-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
4,4'-methylenebis[2,6-diethylaniline] 237-185-4 13680-35-8
Long-term toxicity to fish
Genetic toxicity in vivo
26/03/2018
26/03/2018
11/05/2018
11/05/2018
alkyl amine and alkylbenzenesulphonate - -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018
Barium chloride 233-788-1 10361-37-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Dimethoxymethane 203-714-2 109-87-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Dipotassium hexachloroplatinate 240-979-3 16921-30-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018
Hexachloroplatinic acid 241-010-7 16941-12-1 Genetic toxicity in vivo || Note: testing proposed with Diammonium hexachloroplatinate (EC 241-010-7). Testing proposal is based on concern identified by the registrant. 26/03/2018 11/05/2018
inorganic phosphorus salt 428-310-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Phenol, isopropylated, phosphate (3:1) 273-066-3 68937-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018
Slags, ferromanganese-manufg. 273-728-1 69012-28-8 Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018
C16-(branched), C20-(branched) and C24-(branched)-alkanes 700-992-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
28/02/2018
16/04/2018
16/04/2018
16/04/2018
4-tert-butylpyrocatechol 202-653-9 98-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
ethyl methyl carbonate 433-480-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine 500-191-5 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 701-120-2 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated 614-503-3 68441-62-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Aluminium oxide 215-691-6 1344-28-1 Genetic toxicity in vivo || Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material. 28/02/2018 16/04/2018
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Dimethylamine 204-697-4 124-40-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018
Tetraammineplatinum dichloride 237-706-5 13933-32-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018



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