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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
1-Dodecene, dimers 814-509-8 62132-67-6
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 1-decene, homopolymer, hydrogenated (EC 500-183-1), 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-decene, dimer, unhydrogenated (EC 917-709-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the Substance, 1-decene, homopolymer, hydrogenated (EC 500-183-1), and 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9)
18/03/2021
18/03/2021
18/03/2021
03/05/2021
03/05/2021
03/05/2021
3-aminopropyltriethoxysilane 213-048-4 919-30-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
N,N'-bis(3-aminopropyl)ethylenediamine 234-147-9 10563-26-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Phthalic anhydride 201-607-5 85-44-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Reaction products of n-octanol and acrylic acid, first distillation pitch 938-925-5 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
S-(3-(triethoxysilyl)propyl)octanethioate 436-690-9 220727-26-4
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
(E)-N-(pentan-2-ylidene)hydroxylamine 484-470-6 623-40-5 Reproductive toxicity (pre-natal developmental toxicity) 18/03/2021 03/05/2021
1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether 282-199-6 84144-79-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 18/03/2021 03/05/2021
1,3-diphenyl-2-thiourea 203-004-2 102-08-9 Genetic toxicity in vivo 18/03/2021 03/05/2021
1-imino-1H-isoindol-3-amine 222-426-8 3468-11-9 Genetic toxicity in vivo 18/03/2021 03/05/2021
2-tert-butyl-1,4-dimethoxybenzene 244-216-5 21112-37-8 Genetic toxicity in vivo 18/03/2021 03/05/2021
[3-(2,3-epoxypropoxy)propyl]triethoxysilane 220-011-6 2602-34-8 Genetic toxicity in vivo 18/03/2021 03/05/2021
Bis(2,4,4-trimethylpentyl)phosphinic acid 280-445-7 83411-71-6 Sub-chronic toxicity (90-day): oral 18/03/2021 03/05/2021
Disodium 1-amino-4-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate 274-397-6 70209-99-3 Genetic toxicity in vivo 18/03/2021 03/05/2021
N-(2-nitrophenyl)phosphoric triamide 477-690-9 - Long-term toxicity to fish 18/03/2021 03/05/2021
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/03/2021 03/05/2021
Propanamide, 2-hydroxy-N,N-dimethyl- 609-066-0 35123-06-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/03/2021 03/05/2021
Reaction products of anilinohydroxypolycyclicsulphonic acid coupled twice with diazotised aminonitrophenol, complexes with [3-hydroxy-4-[(2-hydroxy-1-polycyclic)azo]-7-nitropolycyclic-1-sulphonato(3-)]chromium, sodium salts - - Genetic toxicity in vivo 18/03/2021 03/05/2021
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallized with Basic Chromium (III) Sulphate, sodium salts 947-395-4 - Genetic toxicity in vivo 18/03/2021 03/05/2021
Reaction products of diazotised Sodium Picramate coupled with Resorcinol, subsequently coupled with diazotised 4'-Amino-4-Nitrodiphenylamin-2-Sulfonic Acid, at the end metallized with Iron (II) sulphate heptahydrate, sodium salts 946-788-8 - Genetic toxicity in vivo 18/03/2021 03/05/2021
Sodium 1-amino-4-[[3,5-bis[[(chloroacetyl)amino]methyl]-2,4,6-trimethylphenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate 279-365-5 80010-51-1 Genetic toxicity in vivo 18/03/2021 03/05/2021
Soybean oil, epoxidized, Me ester, reaction products with propylene glycol 306-246-8 96690-51-6 Genetic toxicity in vivo 18/03/2021 03/05/2021
Terpenic base 947-968-9 - Genetic toxicity in vivo 18/03/2021 03/05/2021
Triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo 18/03/2021 03/05/2021
3,3'-oxybis(ethyleneoxy)bis(propylamine) 224-207-2 4246-51-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Dimethyl(propyl)amine 213-139-9 926-63-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethyldimethylamine (EC 209-940-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethyldimethylamine (EC 209-940-8)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Hexyl salicylate 228-408-6 6259-76-3
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 - Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021
1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. 600-033-6 1001416-18-7 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine 601-101-8 111497-86-0 Sub-chronic toxicity (90-day): oral 18/02/2021 05/04/2021
4-hydroxybenzophenone 214-507-1 1137-42-4 Genetic toxicity in vivo 18/02/2021 05/04/2021
Adipic acid 204-673-3 124-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
Disodium 4-[4-[[5-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-2,5-dichlorobenzenesulphonate 274-499-0 70247-70-0 Genetic toxicity in vivo 18/02/2021 05/04/2021
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-[(4-methyl-3-sulphonatophenyl)sulphonyl]phenyl]azo]naphthalene-2-sulphonate 286-122-7 85187-33-3 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 18/02/2021 05/04/2021
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxynaphthalene-2-sulphonate 274-437-2 70210-40-1 Genetic toxicity in vivo 18/02/2021 05/04/2021
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-215-4 68475-94-5 Genetic toxicity in vivo 18/02/2021 05/04/2021
m-xylene 203-576-3 108-38-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) 18/02/2021 05/04/2021
p-xylene 203-396-5 106-42-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol 904-153-2 - Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 Genetic toxicity in vivo 18/02/2021 05/04/2021
Hexadecane 208-878-9 544-76-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C10-C13, aromatics, 922-153-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C7-C9, isoalkanes 921-728-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C9-C10, aromatics, >1% naphthalene 946-365-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C9-C11, isoalkanes, cyclics 920-134-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021



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