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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Ethane- 1,2-diol, propoxylated 500-078-0 31923-84-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Link
Propylidynetrimethanol, propoxylated 500-041-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Link
2,2'-azobis[2-methylpropionamidine] dihydrochloride 221-070-0 2997-92-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Link
Nonane-1,9-diol 223-517-5 3937-56-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
05/07/2018
05/07/2018
20/08/2018
20/08/2018
Link
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018 Link
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
Link
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Link
Tetra(isobutyl)thioperoxydicarbamic acid 221-312-5 3064-73-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Link
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018 Link
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018 Link
Bumetrizole 223-445-4 3896-11-5 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018 Link
Dipotassium tetrachloroplatinate 233-050-9 10025-99-7 Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." 18/06/2018 02/08/2018 Link
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/06/2018 02/08/2018 Link
Zinc, bis[O,O-bis(1-methylethyl) phosphorodithioato-.kappa.S]bis(cyclohexanamine)-, (T-4)- 809-986-4 52585-16-7 Genetic toxicity in vivo 18/06/2018 02/08/2018 Link
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Link
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen 701-207-5 1950616-36-0
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
21/05/2018
05/07/2018
05/07/2018
05/07/2018
Link
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Link
Ethylene dibenzoate 202-338-6 94-49-5
Reproductive toxicity (pre-natal developmental toxicity 
Developmental neurotoxicity
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Link
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018 Link
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine 447-920-2 - Reproductive toxicity (pre-natal developmental toxicity) 21/05/2018 05/07/2018 Link
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
Link
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Link
Dihexadecyl peroxodicarbonate 247-611-0 26322-14-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Link
N-methylaniline 202-870-9 100-61-8
Sub-chronic toxicity (90 day): dermal
Reproductive toxicity (extended one-generation reproductive toxicity study)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Link
Triethoxy(vinyl)silane 201-081-7 78-08-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8)
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Link
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018 Link
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Alcohols, C18-22, distn. residues 641-136-6 1160164-88-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) 931-276-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Diammonium hexachloroplatinate 240-973-0 16919-58-7 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018 Link
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Reproductive toxicity (extended one-generation reproductive toxicity study 23/04/2018 07/06/2018 Link
Hexadecyldimethylamine 695-101-5 1275611-65-8 Reproductive toxicity (pre-natal developmental toxicity) 23/04/2018 07/06/2018 Link
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs 931-371-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Link
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018 Link
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) 23/04/2018 07/06/2018 Link
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018 Link
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione 401-540-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
26/03/2018
11/05/2018
11/05/2018
11/05/2018
Link
2,4,4-trimethylpentene 246-690-9 25167-70-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Link
2-methylpentane-2,4-diol 203-489-0 107-41-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Link
4,4'-methylenebis[2,6-diethylaniline] 237-185-4 13680-35-8
Long-term toxicity to fish
Genetic toxicity in vivo
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Link
alkyl amine and alkylbenzenesulphonate - -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Link
Tris(2-butoxyethyl) phosphate 201-122-9 78-51-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Link
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Link
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Link
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Link



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