Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

1 601 - 1 800 / 2 011 tétel megjelenítése.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide	939-581-9	-	Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018	11/05/2018	Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide	931-324-9	-	Sub-chronic toxicity (90-day): oral	02/09/2011	17/10/2011	Details
3-aminopropyltriethoxysilane	213-048-4	919-30-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
3-aminopropyldiethylamine	203-236-4	104-78-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014	05/05/2014 05/05/2014	Details
3-amino-4-octanol	482-070-6	1001354-72-8	Reproductive toxicity (developmental toxicity)	19/11/2010	03/01/2011	Details
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	213-485-0	957-68-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/08/2018 10/08/2018 10/08/2018	24/09/2018 24/09/2018 24/09/2018	Details
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile	300-496-1	93940-97-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid	-	-	Developmental toxicity (pre-natal developmental toxicity)	15/03/2011	29/04/2011	Details
3-[(5-cyano-6-hydroxy-1,4-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]phenyl benzoate	953-951-7	-	7.6.2 Genetic toxicity in vivo	08/03/2024	22/04/2024	Details
3-[(3-{[(3-acetoxy-2,2-dimethylpropylidene)amino]methyl}-3,5,5-trimethylcyclohexyl)imino]-2,2-dimethylpropyl acetate	805-722-7	1064082-81-0	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	17/12/2019	31/01/2020	Details
3-(trimethoxysilyl)propylamine	237-511-5	13822-56-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
3-(trimethoxysilyl)propyl isocyanate	239-415-9	15396-00-6	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate	642-902-2	163802-53-7	Genetic toxicity in vivo	10/03/2017	25/04/2017	Details
3-(trimethoxysilyl)propiononitrile	219-764-3	2526-62-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014	05/05/2014 05/05/2014	Details
3-(triethoxysilyl)propanethiol	238-883-1	14814-09-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
3-(isodecyloxy)propylammonium acetate	249-166-8	28701-67-9	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
3-(dimethylamino)propylurea	401-950-2	31506-43-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	06/06/2023 06/06/2023	21/07/2023 21/07/2023	Details
3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid	434-070-2	-	Sub-chronic toxicity (90-day): oral	18/02/2013	04/04/2013	Details
3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile	257-884-8	52372-36-8	Genetic toxicity in vivo	26/10/2022	12/12/2022	Details
3-(benzothiazol-2-yl)-7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carbonitrile	274-668-9	70546-25-7	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1)	939-448-5	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine	939-485-7	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride	427-370-1	164288-56-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	03/04/2023	22/05/2023	Details
3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate	700-071-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2012 16/05/2012	02/07/2012 02/07/2012	Details
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide	221-088-9	3001-98-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane	229-542-8	6600-31-3	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
3,7-dimethyloctan-1-ol	203-374-5	106-21-8	Reproductive toxicity (pre-natal developmental toxicity)	31/01/2014	17/03/2014	Details
3,7-dimethyloct-6-enenitrile	257-288-8	51566-62-2	Reproductive toxicity (pre-natal developmental toxicity)	03/03/2014	17/04/2014	Details
3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione	413-920-6	-	Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012	12/11/2012	Details
3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione	416-250-2	-	Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012	12/11/2012	Details
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione	401-540-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/03/2018 26/03/2018 26/03/2018	11/05/2018 11/05/2018 11/05/2018	Details
3,6,9,12-tetraoxotridecanol	245-883-5	23783-42-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity)	22/11/2017 22/11/2017	08/01/2018 08/01/2018	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	28/02/2011 28/02/2011	14/04/2011 14/04/2011	Details
3,5-dimethyl-1,2-dioxolane-3,5-diol	237-438-9	13784-51-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt	480-890-9	906532-68-1	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	18/11/2014	02/01/2015	Details
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle	-	-	Genetic toxicity in vivo	16/03/2015	30/04/2015	Details
3,5,5-trimethylhexyl acetate	261-245-9	58430-94-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate	261-665-2	59219-71-5	Sub-chronic toxicity (90-day): oral	24/02/2020	09/04/2020	Details
3,5,5-trimethylhexanoic acid	221-975-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011	15/07/2011 15/07/2011	Details
3,4-dihydroxybenzonitrile	241-367-9	17345-61-8	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
3,4-dihydroxy-1-[(Z)-octadec-9-enyl]pyrrolidine-2,5-dione	700-233-4	-	Bioaccumulation aquatic / sediment Long-term toxicity to fish Sub-chronic toxicity (90-day): oral	04/09/2023 04/09/2023 04/09/2023	19/10/2023 19/10/2023 19/10/2023	Details
3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran	251-090-5	32539-83-6	Genetic toxicity in vivo	14/02/2011	31/03/2011	Details
3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane	262-061-1	60111-54-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
3,3,5-trimethylcyclohexan-1-one	212-855-9	873-94-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
3,3,4,4,5,5,6,6,6-nonafluorohexene	243-053-7	19430-93-4	Sub-chronic toxicity (90 day): inhalation	14/08/2014	28/09/2014	Details
3,3'-oxybis(ethyleneoxy)bis(propylamine)	224-207-2	4246-51-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
3,3'-iminodi(propylamine)	200-261-2	56-18-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid	700-002-8	-	Reproductive toxicity (pre-natal developmental toxicity)	16/07/2012	30/08/2012	Details
2-tert-butylphenol	201-807-2	88-18-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
2-tert-butyl-1,4-dimethoxybenzene	244-216-5	21112-37-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane	941-793-1	-	Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019	10/06/2019	Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane	941-793-1	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7)	17/04/2015	04/06/2015	Details
2-Propyn-1-ol, compd. with methyloxirane	609-530-2	38172-91-7	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
2-propenoic acid, butyl ester, reaction products with butadiene and sulfur	947-895-2	-	Bioaccumulation aquatic / sediment Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/01/2024 15/01/2024 15/01/2024 15/01/2024	29/02/2024 29/02/2024 29/02/2024 29/02/2024	Details
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate	258-053-2	52628-03-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2014 29/04/2014	13/06/2014 13/06/2014	Details
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine	601-101-8	111497-86-0	Sub-chronic toxicity (90-day): oral	18/02/2021	05/04/2021	Details
2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine	601-101-8	111497-86-0	Reproductive toxicity (pre-natal developmental toxicity)	02/06/2014	17/07/2014	Details
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs	307-276-4	97592-79-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Sub-chronic toxicity (90-day): oral	21/10/2011	05/12/2011	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017	16/10/2017	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Chronic toxicity/carcinogenicity Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	14/02/2011 14/02/2011 14/02/2011	31/03/2011 31/03/2011 31/03/2011	Details
2-phosphonobutane-1,2,4-tricarboxylic acid	253-733-5	37971-36-1	Long-term toxicity to fish\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
2-phenylethanol	200-456-2	60-12-8	Reproductive toxicity (two-generation reproductive toxicity)	15/04/2014	30/05/2014	Details
2-phenoxyethyl acrylate	256-360-6	48145-04-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.	308-760-8	98246-87-8	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)-	939-401-9	1469983-41-2	Long-term toxicity to fish \|\|Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8)	15/07/2022	29/08/2022	Details
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol	500-099-5	37625-56-2	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2011	29/08/2011	Details
2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
2-Oxepanone, polymer with 1,4-butanediol	608-670-1	31831-53-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
2-Octyldodecan-1-ol	226-242-9	5333-42-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs.	296-120-8	92257-31-3	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
2-methylpropene	204-066-3	115-11-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation \|\| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
2-methylpropene	204-066-3	115-11-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
2-methylpropane-2-thiol	200-890-2	75-66-1	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1 ) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
2-methylpropan-1-ol	201-148-0	78-83-1	Long-term toxicity to fish \|\|Note: testing proposed with Propan-1-ol (EC no. 200-746-9) \|\|Note: testing proposed with Pentan-1-ol (EC no. 200-752-1)	26/10/2022	12/12/2022	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (two-generation reproductive toxicity)	16/06/2011	01/08/2011	Details
2-methylbut-3-yn-2-ol	204-070-5	115-19-5	Sub-chronic toxicity (90-day): oral	20/04/2015	08/06/2015	Details
2-methyl-1,3-propanediol	412-350-5	2163-42-0	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
2-methoxyethyl acrylate	221-499-3	3121-61-7	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
2-mercaptoethanol	200-464-6	60-24-2	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2011	30/05/2011	Details
2-isocyanatoethyl methacrylate	250-284-7	30674-80-7	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
2-imidazolidone	204-436-4	120-93-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime	605-717-8	174333-80-3	Long-term toxicity to fish	22/06/2017	07/08/2017	Details
2-hydroxy-3-propyl-2H-furan-5-one	821-451-7	78920-10-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant. \|\|	25/11/2019	09/01/2020	Details
2-hydroxy-2-methylpropiophenone	231-272-0	7473-98-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day)	21/10/2019 15/03/2011 15/03/2011 15/03/2011	05/12/2019 29/04/2011 29/04/2011 29/04/2011	Details
2-Hexyldecan-1-ol	219-370-1	2425-77-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
2-ethylhexyl nitrate	248-363-6	27247-96-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	29/04/2011 29/04/2011 29/04/2011	14/06/2011 14/06/2011 14/06/2011	Details
2-ethylhexyl benzoate	226-641-8	5444-75-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
2-ethylhexyl acrylate	203-080-7	103-11-7	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2011 16/05/2011 16/05/2011	30/06/2011 30/06/2011 30/06/2011	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo	30/11/2015	14/01/2016	Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	260-829-0	57583-35-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020 27/01/2020	12/03/2020 12/03/2020 12/03/2020	Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	260-829-0	57583-35-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2016 01/09/2016 01/09/2016	17/10/2016 17/10/2016 17/10/2016	Details
2-ethylhexanoic acid, monoester with propane-1,2-diol	285-503-5	85114-00-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
2-ethylanthraquinone	201-535-4	84-51-5	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
2-ethylaminoethanol	203-797-5	110-73-6	Sub-chronic toxicity (90-day): oral	18/02/2014	04/04/2014	Details
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine	217-461-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012	01/03/2012 01/03/2012	Details
2-ethyl-4-methylimidazole	213-234-5	931-36-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate	204-793-6	126-57-8	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	17/04/2015	04/06/2015	Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate	239-701-3	15625-89-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate	239-701-3	15625-89-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/10/2022	12/12/2022	Details
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate	403-960-2	-	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
2-dibutylaminoethanol	203-057-1	102-81-8	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
2-chloropropane	200-858-8	75-29-6	Reproductive toxicity (two-generation reproductive toxicity)	16/05/2011	30/06/2011	Details
2-chloropropane	200-858-8	75-29-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated	614-503-3	68441-62-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated	614-503-3	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation	15/04/2011 15/04/2011 15/04/2011	30/05/2011 30/05/2011 30/05/2011	Details
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated	614-503-3	68441-62-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed on rabbit. Reproductive toxicity (two-generation reproductive toxicity)	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
2-butyl-2-ethylpropanediol	204-111-7	115-84-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/02/2011 14/02/2011	31/03/2011 31/03/2011	Details
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched	283-219-6	84583-68-6	Sub-chronic toxicity (90-day): oral	12/04/2017	29/05/2017	Details
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol	286-304-6	85204-10-0	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014 17/07/2014	Details
2-butene	203-452-9	107-01-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation \|\| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
2-butene	203-452-9	107-01-7	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation\|\|Note: testing proposed with 2-methylpropene (EC no. 204-066-3)	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone	404-360-3	-	Reproductive toxicity (pre-natal developmental toxicity)	24/05/2013	08/07/2013	Details
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol	608-744-3	32472-85-8	Reproductive toxicity (pre-natal developmental toxicity)	16/03/2015	30/04/2015	Details
2-aminopropane-1,3-diol	208-584-0	534-03-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	17/06/2014 17/06/2014	01/08/2014 01/08/2014	Details
2-aminoethanol, monoester with boric acid	233-829-3	10377-81-8	Sub-chronic toxicity (90-day): oral	17/11/2011	02/01/2012	Details
2-aminoethanol, monoester with boric acid	233-829-3	10377-81-8	Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	01/07/2011 01/07/2011 01/07/2011	15/08/2011 15/08/2011 15/08/2011	Details
2-amino-2-ethylpropanediol	204-101-2	115-70-8	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-amino-1,3-propanediol Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-amino-1,3-propanediol	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate	266-733-5	67584-55-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014 16/05/2014	30/06/2014 30/06/2014 30/06/2014	Details
2-[[(butylamino)carbonyl]oxy]ethyl acrylate	264-036-0	63225-53-6	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	23/03/2020	07/05/2020	Details
2-[2-(2-hydroxyethoxy)ethoxy]ethanol,methanesulfonic acid	817-828-0	80322-82-3	Genetic toxicity in vivo	30/06/2023	14/08/2023	Details
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate	254-588-0	39670-09-2	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate	701-363-4	-	Sub-chronic toxicity (90-day): oral	26/08/2021	11/10/2021	Details
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate	244-311-1	21282-97-3	Genetic toxicity in vivo	29/04/2014	13/06/2014	Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	228-768-4	6358-31-2	7.5.2 Repeated dose toxicity: inhalation	08/03/2024	22/04/2024	Details
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate	248-882-8	28173-59-3	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate	254-959-7	40530-60-7	Genetic toxicity in vivo \|\| Note: testing proposed with Disperse Red 302:1 (EC 248-882-8)	23/11/2020	07/01/2021	Details
2-(dimethylamino)-2-methylpropan-1-ol	230-279-6	7005-47-2	Reproductive toxicity (pre-natal developmental toxicity)	31/01/2014	17/03/2014	Details
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene	618-312-6	898566-17-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
2-(2H-benzotriazol-2-yl)-p-cresol	219-470-5	2440-22-4	Bioaccumulation aquatic / sediment	18/06/2018	02/08/2018	Details
2-(2H-Benzotriazol-2-yl)-6-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)phenol	422-600-5	73936-91-1	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol	221-573-5	3147-75-9	Bioaccumulation aquatic / sediment	15/07/2014	29/08/2014	Details
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol	274-570-6	70321-86-7	Bioaccumulation aquatic / sediment	15/07/2014	29/08/2014	Details
2-(2-Vinyloxyethoxy)ethyl acrylate	451-690-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/12/2017 20/12/2017	05/02/2018 05/02/2018	Details
2-(2-thienyl)ethyl toluene-p-sulphonate	254-911-5	40412-06-4	Genetic toxicity in vivo	06/09/2018	22/10/2018	Details
2-(2-naphthyloxy)ethanol	202-228-8	93-20-9	Genetic toxicity in vivo	16/05/2014	30/06/2014	Details
2-(2-methoxyethoxy)ethanol	203-906-6	111-77-3	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2019	05/12/2019	Details
2-(2-Ethoxyethoxy)-2-methylpropanee	257-196-8	51422-54-9	Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity)	03/02/2016	21/03/2016	Details
2-(2-(2-methoxyethoxy)ethoxy)ethanol	203-962-1	112-35-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2019	05/12/2019	Details
2-(2-(2-ethoxyethoxy)ethoxy)ethanol	203-978-9	112-50-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol	205-592-6	143-22-6	Reproductive toxicity (pre-natal developmental toxicity)	10/08/2018	24/09/2018	Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol	205-592-6	143-22-6	Reproductive toxicity (pre-natal developmental toxicity): 1st PNDT on the registered substance 2nd PNDT with the registered substance // Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6)	27/01/2020	12/03/2020	Details
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate	224-116-8	4203-89-8	Genetic toxicity in vivo	23/03/2020	07/05/2020	Details
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts	232-380-0	8011-86-7	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017	16/10/2017	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (two-generation reproductive toxicity)	14/02/2011	31/03/2011	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2,6-di-tert-butylphenol	204-884-0	128-39-2	Bioaccumulation aquatic / sediment	04/12/2023	18/01/2024	Details
2,6-di-tert-butylphenol	204-884-0	128-39-2	Reproductive toxicity (pre-natal developmental toxicity)	17/06/2020	03/08/2020	Details
2,6-di-tert-butylphenol	204-884-0	128-39-2	Sub-chronic toxicity (90-day): oral	16/05/2011	30/06/2011	Details
2,6,10-trimethyldodecane	622-542-2	3891-98-3	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014 18/02/2014	04/04/2014 04/04/2014 04/04/2014	Details
2,6,10,15,19,23-hexamethyltetracosane	203-825-6	111-01-3	Bioaccumulation aquatic / sediment	14/08/2014	28/09/2014	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (two-generation reproductive toxicity)	02/02/2012	19/03/2012	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (pre-natal developmental toxicity)	29/07/2011	12/09/2011	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	6.1.2 Long-term toxicity to fish	08/03/2024	22/04/2024	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2,5-di-tert-pentylhydroquinone	201-222-2	79-74-3	Sub-chronic toxicity (90-day): oral	31/05/2011	15/07/2011	Details
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone	212-990-3	903-19-5	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
2,4-Pentanedione, peroxide	253-384-9	37187-22-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol	411-220-5	-	Reproductive toxicity (pre-natal developmental toxicity)	25/09/2012	12/11/2012	Details
2,4-dihydroxybenzophenone	205-029-4	131-56-6	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
2,4-di-tert-butylphenol	202-532-0	96-76-4	Sub-chronic toxicity (90-day): oral	16/05/2011	30/06/2011	Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl-	485-230-3	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt	286-344-4	85209-91-2	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated	500-022-5	9014-85-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) \|\|	25/11/2019	09/01/2020	Details
2,4,7,9-tetramethyl-4,7-decanediol	451-160-7	17913-76-7	Long-term toxicity to fish "\|\| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019 17/09/2019	01/11/2019 01/11/2019	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine	426-040-2	25713-60-4	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/06/2011 16/06/2011 16/06/2011 16/06/2011	01/08/2011 01/08/2011 01/08/2011 01/08/2011	Details
2,4,6-trinitrotoluene	204-289-6	118-96-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	04/04/2014 04/04/2014 04/04/2014	19/05/2014 19/05/2014 19/05/2014	Details
2,4,6-triallyloxy-1,3,5-triazine	202-936-7	101-37-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	15/04/2011 15/04/2011	30/05/2011 30/05/2011	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Sub-chronic toxicity (90-day): oral -	22/11/2017 22/11/2017	08/01/2018 08/01/2017	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/05/2020	09/07/2020	Details
2,4,6,8-tetramethylcyclotetrasiloxane	219-137-4	2370-88-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane	219-863-1	2554-06-5	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014 03/03/2014 03/03/2014	17/04/2014 17/04/2014 17/04/2014 17/04/2014	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) Sub-chronic toxicity (90 day): inhalation \|\| Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)	04/10/2013 04/10/2013	18/11/2013 18/11/2013	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4)	25/05/2020	09/07/2020	Details
2,4,4-trimethylpentene	246-690-9	25167-70-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	15/07/2022	29/08/2022	Details
2,4,4-trimethylpentene	246-690-9	25167-70-8	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: There are two testing proposals for this endpoint. Sub-chronic toxicity (90-day): oral	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014 16/05/2014	30/06/2014 30/06/2014 30/06/2014	Details
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid	500-281-4	98362-33-5	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): dermal	15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day)	26/05/2010 26/05/2010 26/05/2010	12/07/2010 12/07/2010 12/07/2010	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2,3-epoxypropyl isopropyl ether	223-672-9	4016-14-2	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide	686-241-8	81058-27-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
2,2`-iminodi(ethylamine),N-(2-aminoethyl)ethane-1,2-diamine	203-865-4	111-40-0	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011 05/04/2011 05/04/2011	20/05/2011 20/05/2011 20/05/2011	Details
2,2`-(octadec-9-enylimino)bisethanol	246-807-3	25307-17-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011 15/07/2011	29/08/2011 29/08/2011 29/08/2011	Details
2,2-dimethylpropane-1,3-diyl dibenzoate	224-081-9	4196-89-8	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate	255-180-5	41026-17-9	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2016 16/12/2016 16/12/2016	30/01/2017 30/01/2017 30/01/2017	Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate	255-180-5	41026-17-9	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014 16/05/2014 16/05/2014	30/06/2014 30/06/2014 30/06/2014 30/06/2014	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details

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