Korábbi/eredmények

Korábbi/eredmények

Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
3,3,5-trimethylcyclohexan-1-one 212-855-9 873-94-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Vinylene carbonate 212-825-5 872-36-6
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/05/2021
20/05/2021
20/05/2021
05/07/2021
05/07/2021
05/07/2021
Details
Vinylene carbonate 212-825-5 872-36-6 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Dec-1-ene 212-819-2 872-05-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Triethyl phosphonoacetate 212-757-6 867-13-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Details
Cobalt oxalate 212-409-3 814-89-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Cobalt oxalate 212-409-3 814-89-1
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Details
bismuth citrate 212-390-1 813-93-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
triethoxy(phenyl)silane 212-305-8 780-69-8 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1)
25/06/2015 10/08/2015 Details
1,1'-[oxybis(ethyleneoxy)]diethylene 212-133-3 764-99-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/03/2023
01/03/2023
17/04/2023
17/04/2023
Details
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017 Details
2,4,6-tri-tert-butylphenol 211-989-5 732-26-3 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2021 16/08/2021 Details
Isopropylcyclohexane 211-792-4 696-29-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Cyclohex-1,2-ylenediamine 211-776-7 694-83-7 Genetic toxicity in vivo 22/09/2022 07/11/2022 Details
Dioctadecyl 3,3'-thiodipropionate 211-750-5 693-36-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 03/04/2023 22/05/2023 Details
Trimethylolpropane Diallyl Ether / 2,2-bis(allyloxymethyl)butan-1-ol / 2,2-bis[(allyloxy)methyl]butan-1-ol 211-661-1 682-09-7
Reproductive toxicity (pre-natal developmental toxicity)
subchronic toxicity (90-day)
26/01/2011
26/01/2011
14/03/2011
14/03/2011
Details
Docosan-1-ol 211-546-6 661-19-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/06/2023
30/06/2023
14/08/2023
14/08/2023
Details
Sodium toluene-4-sulphonate 211-522-5 657-84-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate 
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate 
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2015 16/11/2015 Details
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Decamethylenediamine 211-471-9 646-25-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
Hexadec-1-ene 211-105-8 629-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Tetradecane 211-096-0 629-59-4 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Tridecane 211-093-4 629-50-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hexane-1,6-diol 211-074-0 629-11-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
30/06/2011
30/06/2011
Details
1-methylimidazole 210-484-7 616-47-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
tert-butyl perbenzoate 210-382-2 614-45-9 Long-term toxicity to fish 23/03/2020 07/05/2020 Details
tert-butyl perbenzoate 210-382-2 614-45-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
Triphenylphosphine 210-036-0 603-35-0 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Manganese carbonate 209-942-9 598-62-9 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: Testing proposal is based on concern identified by the registrant.” 03/02/2016 21/03/2016 Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017 Details
Hex-1-ene 209-753-1 592-41-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011 Details
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
4-methylcyclohexanone 209-665-3 589-92-4
6.1.2 Long-term toxicity to fish
7.5.1 Repeated dose toxicity: oral
7.8.2 Developmental toxicity / teratogenicity
08/03/2024
08/03/2024
08/03/2024
22/04/2024
22/04/2024
22/04/2024
Details
3-methylbutanone 209-264-3 563-80-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
Methyl isothiocyanate 209-132-5 556-61-6 Genetic toxicity in vivo 17/11/2011 02/01/2012 Details
Lithium carbonate 209-062-5 554-13-2 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Hexadecane 208-878-9 544-76-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Diisopentyl ether 208-857-4 544-01-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
Details
δ-valerolactone 208-807-1 542-28-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
6-methyl-1,3,5-triazine-2,4-diyldiamine 208-796-3 542-02-9 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014 Details
5-methylheptan-3-one 208-793-7 541-85-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
Hexamethylcyclotrisiloxane 208-765-4 541-05-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
Decamethylcyclopentasiloxane 208-764-9 541-02-6 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017 Details
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Sub-chronic toxicity (90 day): inhalation 31/05/2011 15/07/2011 Details
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Reproductive toxicity (extended one-generation reproductive toxicity study 23/04/2018 07/06/2018 Details
Ethyl 4-oxovalerate 208-728-2 539-88-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with levulinic acid (EC 204-649-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with levulinic acid (EC 204-649-2)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Details
2-aminopropane-1,3-diol 208-584-0 534-03-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Details
cobalt carbonate 208-169-4 513-79-1
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
Cobalt(II) carbonate 208-169-4 513-79-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Barium carbonate 208-167-3 513-77-9 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium carbonate 208-167-3 513-77-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Details
Guanidinium nitrate 208-060-1 506-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/09/2012
25/09/2012
12/11/2012
12/11/2012
Details
Potassium dicyanoargentate 208-047-0 506-61-6 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
1,3-dioxepane 208-015-6 505-65-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
Hexan-6-olide 207-938-1 502-44-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/11/2015
01/11/2015
16/12/2015
16/12/2015
Details
arbonohydrazide 207-837-2 497-18-7
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Quinazolin-4(1H)-one 207-735-8 491-36-1 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Fluoren-9-one 207-630-7 486-25-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
1,8-naphthylenediamine 207-529-8 479-27-6 Genetic toxicity in vivo 22/04/2021 07/06/2021 Details
Calcium carbonate 207-439-9 471-34-1 Sub-chronic toxicity (90 day): inhalation 15/07/2011 29/08/2011 Details
Fluorobenzene 207-321-7 462-06-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
Perfluamine 206-420-2 338-83-0
Genetic toxicity in vivo (In vivo Mammalian Alkaline Comet Assay)
Genetic toxicity in vivo (Mammalian Erythrocyte Micronucleus Test)
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/03/2019
29/03/2019
29/03/2019
29/03/2019
13/05/2019
13/05/2019
13/05/2019
13/05/2019
Details
Perfluamine 206-420-2 338-83-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
Hydrazine 206-114-9 302-01-2 Sub-chronic toxicity (28 day): inhalation 15/07/2011 29/08/2011 Details
1,4-diazabicyclooctane 205-999-9 280-57-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
1,4-diazabicyclooctane 205-999-9 280-57-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
26/10/2022
12/12/2022
12/12/2022
12/12/2022
Details
calcium cyanamide 205-861-8 156-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011 Details
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2017
17/05/2017
03/07/2017
03/07/2017
Details
Mequinol 205-769-8 150-76-5 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2011 14/06/2011 Details
Dichloro(methyl)(phenyl)silane 205-746-2 149-74-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) 04/04/2014 19/05/2014 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
Details
2,2,4-trimethylpentane-1,3-diol 205-619-1 144-19-4 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
Bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity):
1st PNDT on the registered substance
2nd PNDT with the registered substance
// Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6)
27/01/2020 12/03/2020 Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018 Details
Dodecyl methacrylate 205-570-6 142-90-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
O-isopropyl ethylthiocarbamate 205-517-7 141-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Details
dodecamethylpentasiloxane 205-492-2 141-63-9 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7).
25/06/2015 10/08/2015 Details
dodecamethylpentasiloxane 205-492-2 141-63-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Details
decamethyltetrasiloxane 205-491-7 141-62-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014 Details
Trichloro(propyl)silane 205-489-6 141-57-1 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Triethoxy(propyl)silane (EC 219-842-7, CAS 2550-02-9) 04/04/2014 19/05/2014 Details
Bis(2-butoxyethyl) adipate 205-466-0 141-18-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Bis(2-ethylhexyl) fumarate 205-448-2 141-02-6
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Sub-chronic toxicity (90-day): oral 21/10/2011 05/12/2011 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8
Chronic toxicity/carcinogenicity
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Details
Disodium dihydrogen 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate 205-358-3 139-33-3 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Sodium N-lauroylsarcosinate 205-281-5 137-16-6 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Note: testing proposed with N-methyl-N-[C18-(unsaturated)alkanoyl]glycine (EC no. 701-177-3) 30/06/2023 14/08/2023 Details
Sodium N-lauroylsarcosinate 205-281-5 137-16-6 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
Sodium N-lauroylsarcosinate 205-281-5 137-16-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Details
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
bis(2,4-dichlorobenzoyl) peroxide 205-094-9 133-14-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
Details
2,4-dihydroxybenzophenone 205-029-4 131-56-6 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Bioaccumulation aquatic / sediment 04/12/2023 18/01/2024 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020 Details
Diphenyl sulphone 204-853-1 127-63-9 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
2,2,2',2'-Tetrakis(hydroxymethyl)-3,3'-oxydipropan-1-ol 204-794-1 126-58-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/04/2022 16/05/2022 Details
2,2,2`,2`-Tetrakis(hydroxymethyl)-3,3`-oxydipropan-1-ol 204-794-1 126-58-9 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate 204-793-6 126-57-8 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 17/04/2015 04/06/2015 Details
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant. 23/04/2018 07/06/2018 Details
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Dimethylpropane-1,3-diol 204-781-0 126-30-7
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day)
26/01/2011
26/01/2011
14/03/2011
14/03/2011
Details
Pleuromulin 204-747-5 125-65-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
06/09/2018
22/10/2018
22/10/2018
22/10/2018
Details
Dimethylamine 204-697-4 124-40-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Decane 204-686-4 124-18-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Adipic acid 204-673-3 124-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021 Details
C,C'-azodi(formamide) 204-650-8 123-77-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/11/2021 10/01/2022 Details
4-oxovaleric acid 204-649-2 123-76-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/12/2018
10/12/2018
24/01/2019
24/01/2019
Details
Pentane-2,4-dione 204-634-0 123-54-6
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
3-methylbutan-1-ol 204-633-5 123-51-3 Long-term toxicity to fish||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) 22/09/2022 07/11/2022 Details
4-hydroxy-4-methylpentan-2-one 204-626-7 123-42-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2016
01/09/2016
17/10/2016
17/10/2016
Details
Choline hydroxide 204-625-1 123-41-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) 25/05/2020 09/07/2020 Details
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) 204-613-6 123-26-2
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0
Sub-chronic toxicity (90 day): oral
30/09/2015
30/09/2015
30/09/2015
16/11/2015
16/11/2015
16/11/2015
Details
4-phenylbutenone 204-555-1 122-57-6 Genetic toxicity in vivo 23/03/2020 07/05/2020 Details
Trimethyl borate 204-468-9 121-43-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with boric acid.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with boric acid.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with boric acid.
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
Details
4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
2-imidazolidone 204-436-4 120-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
1,2-dihydroxybenzene,pyrocatechol 204-427-5 120-80-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
1,3-diphenylpropane-1,3-dione 204-398-9 120-46-7
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
6,6`-di-tert-butyl-2,2`-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
2,4,6-trinitrotoluene 204-289-6 118-96-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
04/04/2014
04/04/2014
04/04/2014
19/05/2014
19/05/2014
19/05/2014
Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (pre-natal developmental toxicity) 31/07/2015 14/09/2015 Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Details
Hydroxyacetone 204-124-8 116-09-6 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Linalyl acetate 204-116-4 115-95-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/06/2020 03/08/2020 Details
2-butyl-2-ethylpropanediol 204-111-7 115-84-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
31/03/2011
31/03/2011
Details
2,2-Bis(hydroxymethyl)-1,3-propanediol (pentaerythritol) 204-104-9 115-77-5 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Details
Pentaerythritol 204-104-9 115-77-5 Long-term toxicity to fish 03/05/2023 19/06/2023 Details
2-amino-2-ethylpropanediol 204-101-2 115-70-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
2-methylbut-3-yn-2-ol 204-070-5 115-19-5 Sub-chronic toxicity (90-day): oral 20/04/2015 08/06/2015 Details
2-methylpropene 204-066-3 115-11-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Sub-chronic toxicity (90 day): inhalation || Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
Details
2-methylpropene 204-066-3 115-11-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Propene 204-062-1 115-07-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with ethylene (EC no. 200-815-3)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
2'-phenylacetohydrazide 204-055-3 114-83-0 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
Icosane 204-018-1 112-95-8 Reproductive toxicity (two-generation reproductive toxicity)// Note: Testing proposed with Hydrocarbon, C9-C12, normal, isoalkane, cyclics, 2-25% aromatics; Hydrocarbon, C16-C20, normal, isoalkane cyclics, 2-30% aromatics 02/07/2013 16/08/2013 Details
Octadec-1-ene 204-012-9 112-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Tridecan-1-ol 203-998-8 112-70-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 10/05/2022 27/06/2022 Details
2-(2-(2-ethoxyethoxy)ethoxy)ethanol 203-978-9 112-50-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) 21/10/2021 07/12/2021 Details
Dodec-1-ene 203-968-4 112-41-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Dodecane 203-967-9 112-40-3 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
undec-10-enoic acid 203-965-8 112-38-9 Long-term toxicity to fish 16/10/2014 01/12/2014 Details
undec-10-enoic acid 203-965-8 112-38-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/05/2021
20/05/2021
05/07/2021
05/07/2021
Details
2-(2-(2-methoxyethoxy)ethoxy)ethanol 203-962-1 112-35-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
Decanal 203-957-4 112-31-2 Reproductive toxicity (pre-natal developmental toxicity) 21/10/2021 07/12/2021 Details
Bis(2-chloroethoxy)methane 203-920-2 111-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
31/03/2011
31/03/2011
Details
2-(2-methoxyethoxy)ethanol 203-906-6 111-77-3 Reproductive toxicity (pre-natal developmental toxicity) 21/10/2019 05/12/2019 Details
Heptanal 203-898-4 111-71-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
Heptanal 203-898-4 111-71-7 Reproductive toxicity (extended one-generation reproductive toxicity study)

|| Note: testing proposed with Heptanoic acid (CAS No. 111-14-8)
25/11/2019 09/01/2020 Details
Heptan-1-ol 203-897-9 111-70-6
Long-term toxicity to fish
Long-term toxicity to fish
Sub-chronic toxicity (90 day): Oral
04/09/2012
18/02/2014
04/09/2012
19/10/2012
04/04/2014
19/10/2012
Details
Oct-1-ene 203-893-7 111-66-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
2,2'-iminodi(ethylamine) 203-865-4 111-40-0
Reproductive toxicity (extended one-generation reproductive toxicity study
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
2,2`-iminodi(ethylamine),N-(2-aminoethyl)ethane-1,2-diamine 203-865-4 111-40-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
05/04/2011
05/04/2011
05/04/2011
20/05/2011
20/05/2011
20/05/2011
Details
N,N,N',N'-tetramethylhexamethylenediamine 203-842-9 111-18-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
Heptanoic acid 203-838-7 111-14-8 Long-term toxicity to fish 31/01/2023 17/03/2023 Details
Heptanoic acid 203-838-7 111-14-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 24/07/2019 09/09/2019 Details
Heptanoic acid 203-838-7 111-14-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Details
N-(2-hydroxypropyl)oleamide 203-828-2 111-05-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Details
2,6,10,15,19,23-hexamethyltetracosane 203-825-6 111-01-3 Bioaccumulation aquatic / sediment 14/08/2014 28/09/2014 Details
2-ethylaminoethanol 203-797-5 110-73-6 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
Butane-1,4-diol 203-786-5 110-63-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/04/2021 07/06/2021 Details
Heptan-2-one 203-767-1 110-43-0 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
Maleic acid 203-742-5 110-16-7 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020 Details
5-methylhexan-2-one 203-737-8 110-12-3 Reproductive toxicity (pre-natal developmental toxicity) 14/02/2011 31/03/2011 Details
Di-tert-butyl peroxide 203-733-6 110-05-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Details
Diethylamine 203-716-3 109-89-7 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dimethylamine (CAS 124-40-3) 21/09/2020 05/11/2020 Details
Dimethoxymethane 203-714-2 109-87-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Butyronitrile 203-700-6 109-74-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
tert-butyl peroxyisobutyrate 203-650-5 109-13-7 Genetic toxicity in vivo 15/07/2014 29/08/2014 Details
4-methylmorpholine 203-640-0 109-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
Melamine 203-615-4 108-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/05/2016 01/07/2016 Details
Hexahydro-1,3,5-trimethyl-1,3,5-triazine 203-612-8 108-74-7 Genetic toxicity - EU Method B.12 11/01/2011 25/02/2011 Details
m-phenylene di(acetate) 203-596-2 108-58-7 Genetic toxicity in vivo 27/01/2020 12/03/2020 Details
m-cresol 203-577-9 108-39-4 Long-term toxicity to fish|| Note: testing proposed with p-cresol (EC no. 203-398-6) 10/05/2022 27/06/2022 Details
m-xylene 203-576-3 108-38-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) 18/02/2021 05/04/2021 Details
Diisopropyl ether 203-560-6 108-20-3 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
4-methylpentan-2-one 203-550-1 108-10-1 Long-term toxicity to fish 06/06/2023 21/07/2023 Details
3-mercaptopropionic acid 203-537-0 107-96-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/09/2023
04/09/2023
19/10/2023
19/10/2023
Details
3-Sulfanylpropanoic acid 203-537-0 107-96-0
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
05/04/2011
05/04/2011
05/04/2011
20/05/2011
20/05/2011
20/05/2011
Details
Pentan-2-one 203-528-1 107-87-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
7-hydroxycitronellal 203-518-7 107-75-5
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2023
31/01/2023
31/01/2023
17/03/2023
17/03/2023
17/03/2023
Details
tert-butyl peracetate 203-514-5 107-71-1 Genetic toxicity in vivo 03/04/2023 22/05/2023 Details