Tidigare/resultat
Tidigare/resultat
Tidigare/resultat
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate | 234-204-8 | 10595-49-0 | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2020 | 01/02/2021 | Details | |
| methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Sub-chronic toxicity (90-day): oral | 16/12/2020 | 01/02/2021 | Details | |
| methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate | 16/12/2016 | 30/01/2017 | Details | |
| Methylamine | 200-820-0 | 74-89-5 | Genetic toxicity in vivo | 14/02/2011 | 31/03/2011 | Details | |
| Methylphosphonic acid | 213-607-2 | 993-13-5 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
| methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) | 16/03/2015 | 30/04/2015 | Details | |
| methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) | 03/10/2023 | 17/11/2023 | Details | |
| Middle distillate from refinery proces cofeeding vegetable oil | 938-793-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2013 | 18/10/2013 | Details | |
| Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol | 700-427-9 | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
01/12/2010 01/12/2010 01/12/2010 |
17/01/2011 17/01/2011 17/01/2011 |
Details | |
| Morpholine, 4-C12-14-alkyl derivs. | 800-906-3 | 1402434-48-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
| Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape | 231-955-3 | 7782-42-5 | Long-term toxicity to fish | 03/11/2011 | 19/12/2011 | Details | |
| N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2012 17/04/2012 |
01/06/2012 01/06/2012 |
Details | |
| N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide | 435-860-1 | 214417-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
| N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine | 229-761-9 | 6711-48-4 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) | 22/09/2022 | 07/11/2022 | Details | |
| N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] | 241-523-6 | 17526-94-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
| N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] | 258-981-8 | 54112-23-1 |
Long-term toxicity to fish Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. |
31/08/2015 | 15/10/2015 | Details | |
| N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] | 258-981-8 | 54112-23-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
| N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide | 419-710-0 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
12/12/2014 12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 26/01/2015 |
Details | |
| N,N'-bis(3-aminopropyl)ethylenediamine | 234-147-9 | 10563-26-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
| N,N'-diphenyl-p-phenylenediamine | 200-806-4 | 74-31-7 |
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
| N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) | 204-613-6 | 123-26-2 |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0 Sub-chronic toxicity (90 day): oral |
30/09/2015 30/09/2015 30/09/2015 |
16/11/2015 16/11/2015 16/11/2015 |
Details | |
| N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide) | 227-563-7 | 5888-87-9 | Genetic toxicity in vivo | 18/09/2014 | 03/11/2014 | Details | |
| N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine | 695-748-3 | 65286-55-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
| N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine | 264-438-6 | 63738-22-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
| N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) | 221-220-5 | 3033-62-3 |
7.8.1 Toxicity to reproduction 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
| N,N,N',N'-tetramethylhexamethylenediamine | 203-842-9 | 111-18-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
| N,N,N`,N`,N``-Pentamethyl-N-C16-18 (even numbered) C18 unsat.-alkyl-1,3-propanediammonium chloride | 629-716-7 | 1211950-04-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
| N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine | 251-459-0 | 33329-35-0 | Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound | 29/04/2014 | 13/06/2014 | Details | |
| N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
| N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine | 278-817-9 | 78014-16-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
| N,N-dimethyldecan-1-amide | 238-405-1 | 14433-76-2 | Long-term toxicity to fish | 15/07/2011 | 29/08/2011 | Details | |
| N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea | 876-151-9 | 2292123-68-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 |
Details | |
| N-(1,1-dimethyl-3-oxobutyl)acrylamide | 220-713-2 | 2873-97-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
| N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-hydroxy-4-[[2-methoxy-5-[(phenylamino)carbonyl]phenyl]azo]naphthalene-2-carboxamide | 235-425-2 | 12225-06-8 |
7.5.2 Repeated dose toxicity: inhalation 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
| N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate | 247-161-5 | 25646-71-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
| N-(2-ethylhexyl)isononan-1-amide | 810-288-7 | 1700656-13-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
| N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant | 21/01/2021 | 08/03/2021 | Details | |
| N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
| N-(2-hydroxypropyl)oleamide | 203-828-2 | 111-05-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
| N-(2-nitrophenyl)phosphoric triamide | 477-690-9 | - | Long-term toxicity to fish | 18/03/2021 | 03/05/2021 | Details | |
| N-(3-(trimethoxysilyl)propyl)ethylenediamine | 217-164-6 | 1760-24-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
| N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine | 628-863-4 | 1219458-14-6 | Reproductive toxicity (pre-natal developmental toxicity) | 24/01/2019 | 11/03/2019 | Details | |
| N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine | 628-863-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| N-(3-aminopropyl)-N`-[3-(C16-18 (evennumbered), C18 unsaturated alkyl amino)propyl]propane-1,3-diamine | 628-862-9 | 1219458-11-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
| N-(3-aminopropyl)iminodiethanol | 225-642-0 | 4985-85-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
| N-(4-amino-9,10-dihydro-3-methoxy-9,10-dioxo-1-anthryl)-4-methylbenzenesulphonamide | 201-369-2 | 81-68-5 | Genetic toxicity in vivo | 20/05/2021 | 05/07/2021 | Details | |
| N-(C16-C18)alkyl(C16-C18)alkane-1-amine | 629-721-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 |
Details | |
| N-(cyclohexylthio)phthalimide | 241-774-1 | 17796-82-6 |
Bioaccumulation: aquatic / sediment Long-term or reproductive toxicity to birds Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 01/07/2011 01/07/2011 17/12/2012 |
15/08/2011 15/08/2011 15/08/2011 15/08/2011 31/01/2013 |
Details | |
| N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine | 231-701-1 | 7691-02-3 |
Reproductive toxicity (pre-natal developmental toxicity)
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” Sub-chronic toxicity (90 day): inhalation
“|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)” |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
| N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide | 700-208-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2018 | 19/11/2018 | Details | |