Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate | 253-981-4 | 38517-37-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) || Note: Testing proposal is based on concern identified by the registrant. | 17/12/2019 | 31/01/2020 | Details | |
bis(3,5,5-trimethylhexanoyl) peroxide | 223-356-0 | 3851-87-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts | 609-542-8 | 383178-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine | 500-101-4 | 38294-64-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
2-Propyn-1-ol, compd. with methyloxirane | 609-530-2 | 38172-91-7 | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride | 253-781-7 | 38103-06-9 | Sub-chronic toxicity (90-day): oral | 27/01/2020 | 12/03/2020 | Details | |
2-phosphonobutane-1,2,4-tricarboxylic acid | 253-733-5 | 37971-36-1 |
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol | 500-099-5 | 37625-56-2 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2011 | 29/08/2011 | Details | |
2,4-Pentanedione, peroxide | 253-384-9 | 37187-22-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
Octa-1,7-diene | 223-054-9 | 3710-30-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene | 807-113-1 | 3709-71-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
2-Oxepanone, polymer with 1,6-hexanediol | 609-271-5 | 36609-29-7 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol |
16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 |
Details | |
2,2-dimethylpropan-1-ol, tribromo derivative | 253-057-0 | 36483-57-5 | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Diundecyl phthalate | 222-884-9 | 3648-20-2 | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
Dioctyltin dilaurate | 222-883-3 | 3648-18-8 | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid | 500-090-6 | 36425-16-8 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a structurally related substance (small vinyl ester) Sub-chronic toxicity (90-day): oral || Note: testing proposed with a structurally related substance (small vinyl ester) |
31/05/2016 31/05/2016 |
15/07/2016 15/07/2016 |
Details | |
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid | 500-089-0 | 36425-15-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
1,3-bis(isocyanatomethyl)benzene | 222-852-4 | 3634-83-1 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/02/2011 | 31/03/2011 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine | 252-899-6 | 36177-92-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): ora |
07/10/2016 07/10/2016 |
21/11/2016 21/11/2016 |
Details | |
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea | 436-230-7 | 359406-89-6 | Sub-chronic toxicity (90-day): oral | 06/03/2012 | 20/04/2012 | Details | |
N,N''-propane-1,3-diylbis[N'-octadecylurea | 252-667-4 | 35674-65-8 | Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) | 29/03/2016 | 13/05/2016 | Details | |
Triethoxy(2,4,4-trimethylpentyl)silane | 252-558-1 | 35435-21-3 |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 |
Details | |
Triethoxy(2,4,4-trimethylpentyl)silane | 252-558-1 | 35435-21-3 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
Trinonyl benzene-1,2,4-tricarboxylate | 252-552-9 | 35415-27-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
11/11/2016 11/11/2016 |
03/01/2017 03/01/2017 |
Details | |
Propanamide, 2-hydroxy-N,N-dimethyl- | 609-066-0 | 35123-06-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/03/2021 | 03/05/2021 | Details | |
Propanamide, 2-hydroxy-N,N-dimethyl- | 609-066-0 | 35123-06-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2021 | 07/12/2021 | Details | |
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate | 252-173-9 | 34730-59-1 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2014 | 13/06/2014 | Details | |
triethoxy(3-thiocyanatopropyl)silane | 252-161-3 | 34708-08-2 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
1-butylpyrrolidin-2-one | 222-437-8 | 3470-98-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/01/2022 | 11/03/2022 | Details | |
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant. |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 27/01/2020 | 12/03/2020 | Details | |
tert-butyl α,α-dimethylbenzyl peroxide | 222-389-8 | 3457-61-2 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/03/2015 | 30/04/2015 | Details | |
tert-butyl α,α-dimethylbenzyl peroxide | 222-389-8 | 3457-61-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Tris(nitrato-O)nitrosylruthenium | 252-068-8 | 34513-98-9 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate | 252-029-5 | 34443-12-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate | 252-029-5 | 34443-12-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 05/05/2014 |
Details | |
trimethoxy(2,4,4-trimethylpentyl)silane | 251-995-5 | 34396-03-7 | Long-term toxicity to fish | 26/10/2022 | 12/12/2022 | Details | |
trimethoxy(2,4,4-trimethylpentyl)silane | 251-995-5 | 34396-03-7 |
Sub-chronic toxicity (90-day): oral
Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) " |
25/06/2015 | 10/08/2015 | Details | |
Bisisobutyryl peroxide | 222-340-0 | 3437-84-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 19/05/2014 |
Details | |
tert-pentyl hydroperoxide | 222-321-7 | 3425-61-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
07/10/2016 07/10/2016 |
21/11/2016 21/11/2016 |
Details | |
tert-pentyl hydroperoxide | 222-321-7 | 3425-61-4 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1) | 251-846-4 | 34140-91-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
3-Ethenyl-5-methyl-2-oxazolidinone | 809-852-5 | 3395-98-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
Sodium hexahydroxoantimonate | 251-735-0 | 33908-66-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
Perfluamine | 206-420-2 | 338-83-0 |
Genetic toxicity in vivo (In vivo Mammalian Alkaline Comet Assay) Genetic toxicity in vivo (Mammalian Erythrocyte Micronucleus Test) Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
29/03/2019 29/03/2019 29/03/2019 29/03/2019 |
13/05/2019 13/05/2019 13/05/2019 13/05/2019 |
Details | |
Perfluamine | 206-420-2 | 338-83-0 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one | 251-649-3 | 33704-61-9 | Reproductive toxicity (pre-natal developmental toxicity) | 30/06/2023 | 14/08/2023 | Details | |
Diisononyl adipate | 251-646-7 | 33703-08-1 |
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) |
03/05/2023 03/05/2023 |
19/06/2023 19/06/2023 |
Details | |
sodium O,O-diethyl dithiophosphate || Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5) | 222-079-2 | 3338-24-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine | 251-459-0 | 33329-35-0 | Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound | 29/04/2014 | 13/06/2014 | Details | |
Propylidynetrimethyl trimethacrylate | 221-950-4 | 3290-92-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/04/2019 | 10/06/2019 | Details | |
Propylidynetrimethyl trimethacrylate | 221-950-4 | 3290-92-4 | Reproductive toxicity (pre-natal developmental toxicity) | 31/05/2016 | 15/07/2016 | Details | |
1,1,3,3-tetramethyldisiloxane | 221-906-4 | 3277-26-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran | 251-090-5 | 32539-83-6 | Genetic toxicity in vivo | 14/02/2011 | 31/03/2011 | Details | |
Ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate] | 251-073-2 | 32509-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
4,4'-Isopropylidenediphenol, ethoxylated | 500-082-2 | 32492-61-8 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol | 608-744-3 | 32472-85-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/03/2015 | 30/04/2015 | Details | |
Furan-2,5-dicarboxylic acid | 221-800-8 | 3238-40-2 | Reproductive toxicity (pre-natal developmental toxicity) | 27/05/2019 | 11/07/2019 | Details | |
4-tert-butylcyclohexyl acetate | 250-954-9 | 32210-23-4 |
Sub-chronic toxicity (90-day): oral || Note: testing proposed with cis-4-tert-butylcyclohexyl acetate |
24/02/2020 | 09/04/2020 | Details | |
Hydroxyethylated 2-butyne-1,4-diol | 608-711-3 | 32167-31-0 | Sub-chronic toxicity (90-day): oral | 17/06/2014 | 01/08/2014 | Details | |
Formaldehyde, oligomeric reaction products with aniline and phosgene | 500-079-6 | 32055-14-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate | 915-277-1 | 32052-51-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Ethane- 1,2-diol, propoxylated | 500-078-0 | 31923-84-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
2-Oxepanone, polymer with 1,4-butanediol | 608-670-1 | 31831-53-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
Tris(2,4-ditert-butylphenyl) phosphite | 250-709-6 | 31570-04-4 | Reproductive toxicity (pre-natal developmental toxicity) | 28/11/2022 | 12/01/2023 | Details | |
3-(dimethylamino)propylurea | 401-950-2 | 31506-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 |
Details | |
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol | 221-573-5 | 3147-75-9 | Bioaccumulation aquatic / sediment | 15/07/2014 | 29/08/2014 | Details | |
2-methoxyethyl acrylate | 221-499-3 | 3121-61-7 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
Potassium 3-sulphonatopropyl acrylate | 250-465-0 | 31098-20-1 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6) | 250-437-8 | 31024-56-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether | 221-453-2 | 3101-60-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2014 17/06/2014 17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 01/08/2014 01/08/2014 |
Details | |
A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate | 250-418-4 | 30989-05-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2011 28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 14/04/2011 |
Details | |
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate | 250-418-4 | 30989-05-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
Fatty acids, C12-14 (even numbered), methyl ester | 629-776-4 | 308065-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 15/11/2021 |
Details | |
trimethoxyoctylsilane | 221-338-7 | 3069-40-7 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) | 07/08/2015 | 22/09/2015 | Details | |
Trimethoxyoctylsilane | 221-338-7 | 3069-40-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine | 221-336-6 | 3069-29-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
2-isocyanatoethyl methacrylate | 250-284-7 | 30674-80-7 | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
Tetra(isobutyl)thioperoxydicarbamic acid | 221-312-5 | 3064-73-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 |
Details | |
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-070-7 | 30583-72-3 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane | 608-489-8 | 30499-70-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 10/08/2015 |
Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) | 221-220-5 | 3033-62-3 |
7.8.1 Toxicity to reproduction 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
hex-3-yne-2,5-diol | 221-209-5 | 3031-66-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
bis(2-dimethylaminoethyl)(methyl)amine | 221-201-1 | 3030-47-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate | 443-860-6 | 302776-68-7 | Long-term toxicity to fish | 16/08/2011 | 30/09/2011 | Details | |
Hydrazine | 206-114-9 | 302-01-2 | Sub-chronic toxicity (28 day): inhalation | 15/07/2011 | 29/08/2011 | Details | |
Cyclohexylidenebis[tert-butyl] peroxide | 221-111-2 | 3006-86-8 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
tert-butyl 2-ethylperoxyhexanoate | 221-110-7 | 3006-82-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 30/05/2011 |
Details | |
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide | 221-088-9 | 3001-98-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |