Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate 253-981-4 38517-37-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) || Note: Testing proposal is based on concern identified by the registrant. 17/12/2019 31/01/2020 Details
bis(3,5,5-trimethylhexanoyl) peroxide 223-356-0 3851-87-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Details
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts 609-542-8 383178-66-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine 500-101-4 38294-64-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
2-Propyn-1-ol, compd. with methyloxirane 609-530-2 38172-91-7 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
2-phosphonobutane-1,2,4-tricarboxylic acid 253-733-5 37971-36-1
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol 500-099-5 37625-56-2 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2011 29/08/2011 Details
2,4-Pentanedione, peroxide 253-384-9 37187-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Details
Octa-1,7-diene 223-054-9 3710-30-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene 807-113-1 3709-71-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Details
2-Oxepanone, polymer with 1,6-hexanediol 609-271-5 36609-29-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
16/10/2014
16/10/2014
01/12/2014
01/12/2014
Details
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
Diundecyl phthalate 222-884-9 3648-20-2 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022 Details
Dioctyltin dilaurate 222-883-3 3648-18-8 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid 500-090-6 36425-16-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a structurally related substance (small vinyl ester)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with a structurally related substance (small vinyl ester)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
Details
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid 500-089-0 36425-15-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Details
1,3-bis(isocyanatomethyl)benzene 222-852-4 3634-83-1 6.1.2 Long-term toxicity to fish 08/03/2024 22/04/2024 Details
N-butylbenzenesulphonamide 222-823-6 3622-84-2 Reproductive toxicity (pre-natal developmental toxicity) 14/02/2011 31/03/2011 Details
N-butylbenzenesulphonamide 222-823-6 3622-84-2 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016 Details
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): ora
07/10/2016
07/10/2016
21/11/2016
21/11/2016
Details
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea 436-230-7 359406-89-6 Sub-chronic toxicity (90-day): oral 06/03/2012 20/04/2012 Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
Details
Trinonyl benzene-1,2,4-tricarboxylate 252-552-9 35415-27-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
03/01/2017
03/01/2017
Details
Propanamide, 2-hydroxy-N,N-dimethyl- 609-066-0 35123-06-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/03/2021 03/05/2021 Details
Propanamide, 2-hydroxy-N,N-dimethyl- 609-066-0 35123-06-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2021 07/12/2021 Details
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate 252-173-9 34730-59-1 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014 Details
triethoxy(3-thiocyanatopropyl)silane 252-161-3 34708-08-2
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
Details
1-butylpyrrolidin-2-one 222-437-8 3470-98-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/01/2022 11/03/2022 Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant.
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
1-imino-1H-isoindol-3-amine 222-426-8 3468-11-9 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
1-imino-1H-isoindol-3-amine 222-426-8 3468-11-9 Genetic toxicity in vivo 27/01/2020 12/03/2020 Details
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/03/2015 30/04/2015 Details
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Details
Tris(nitrato-O)nitrosylruthenium 252-068-8 34513-98-9 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
Details
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Sub-chronic toxicity (90-day): oral
Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) "
25/06/2015 10/08/2015 Details
Bisisobutyryl peroxide 222-340-0 3437-84-1
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/04/2014
04/04/2014
04/04/2014
19/05/2014
19/05/2014
19/05/2014
Details
tert-pentyl hydroperoxide 222-321-7 3425-61-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
07/10/2016
07/10/2016
21/11/2016
21/11/2016
Details
tert-pentyl hydroperoxide 222-321-7 3425-61-4 Genetic toxicity in vivo 21/03/2014 05/05/2014 Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1) 251-846-4 34140-91-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
3-Ethenyl-5-methyl-2-oxazolidinone 809-852-5 3395-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Details
Sodium hexahydroxoantimonate 251-735-0 33908-66-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
Perfluamine 206-420-2 338-83-0
Genetic toxicity in vivo (In vivo Mammalian Alkaline Comet Assay)
Genetic toxicity in vivo (Mammalian Erythrocyte Micronucleus Test)
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/03/2019
29/03/2019
29/03/2019
29/03/2019
13/05/2019
13/05/2019
13/05/2019
13/05/2019
Details
Perfluamine 206-420-2 338-83-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
Details
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one 251-649-3 33704-61-9 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2023 14/08/2023 Details
Diisononyl adipate 251-646-7 33703-08-1
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
03/05/2023
03/05/2023
19/06/2023
19/06/2023
Details
sodium O,O-diethyl dithiophosphate || Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5) 222-079-2 3338-24-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine 251-459-0 33329-35-0 Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound 29/04/2014 13/06/2014 Details
Propylidynetrimethyl trimethacrylate 221-950-4 3290-92-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/04/2019 10/06/2019 Details
Propylidynetrimethyl trimethacrylate 221-950-4 3290-92-4 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016 Details
1,1,3,3-tetramethyldisiloxane 221-906-4 3277-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran 251-090-5 32539-83-6 Genetic toxicity in vivo 14/02/2011 31/03/2011 Details
Ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate] 251-073-2 32509-66-3 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014 Details
4,4'-Isopropylidenediphenol, ethoxylated 500-082-2 32492-61-8
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol 608-744-3 32472-85-8 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015 Details
Furan-2,5-dicarboxylic acid 221-800-8 3238-40-2 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate
24/02/2020 09/04/2020 Details
Hydroxyethylated 2-butyne-1,4-diol 608-711-3 32167-31-0 Sub-chronic toxicity (90-day): oral 17/06/2014 01/08/2014 Details
Formaldehyde, oligomeric reaction products with aniline and phosgene 500-079-6 32055-14-4 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) 01/04/2022 16/05/2022 Details
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate 915-277-1 32052-51-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
Ethane- 1,2-diol, propoxylated 500-078-0 31923-84-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
05/07/2018
05/07/2018
05/07/2018
20/08/2018
20/08/2018
20/08/2018
Details
2-Oxepanone, polymer with 1,4-butanediol 608-670-1 31831-53-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Details
Tris(2,4-ditert-butylphenyl) phosphite 250-709-6 31570-04-4 Reproductive toxicity (pre-natal developmental toxicity) 28/11/2022 12/01/2023 Details
3-(dimethylamino)propylurea 401-950-2 31506-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/06/2023
06/06/2023
21/07/2023
21/07/2023
Details
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol 221-573-5 3147-75-9 Bioaccumulation aquatic / sediment 15/07/2014 29/08/2014 Details
2-methoxyethyl acrylate 221-499-3 3121-61-7 Genetic toxicity in vivo 21/03/2014 05/05/2014 Details
Potassium 3-sulphonatopropyl acrylate 250-465-0 31098-20-1 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6) 250-437-8 31024-56-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether 221-453-2 3101-60-8
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2014
17/06/2014
17/06/2014
17/06/2014
01/08/2014
01/08/2014
01/08/2014
01/08/2014
Details
A mixture of cis- and trans-cyclohexadec-8-en-1-one 401-700-2 3100-36-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
28/11/2022
12/01/2023
12/01/2023
12/01/2023
Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
28/02/2011
14/04/2011
14/04/2011
14/04/2011
Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
Fatty acids, C12-14 (even numbered), methyl ester 629-776-4 308065-15-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
Details
trimethoxyoctylsilane 221-338-7 3069-40-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) 07/08/2015 22/09/2015 Details
Trimethoxyoctylsilane 221-338-7 3069-40-7
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
27/09/2017
27/09/2017
13/11/2017
13/11/2017
Details
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine 221-336-6 3069-29-2
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Details
2-isocyanatoethyl methacrylate 250-284-7 30674-80-7 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020 Details
Tetra(isobutyl)thioperoxydicarbamic acid 221-312-5 3064-73-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Details
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-070-7 30583-72-3
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
Details
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane 608-489-8 30499-70-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
25/06/2015
10/08/2015
10/08/2015
10/08/2015
Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
Details
N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) 221-220-5 3033-62-3
7.8.1 Toxicity to reproduction
7.8.2 Developmental toxicity / teratogenicity
08/03/2024
08/03/2024
22/04/2024
22/04/2024
Details
hex-3-yne-2,5-diol 221-209-5 3031-66-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
bis(2-dimethylaminoethyl)(methyl)amine 221-201-1 3030-47-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate 443-860-6 302776-68-7 Long-term toxicity to fish 16/08/2011 30/09/2011 Details
Hydrazine 206-114-9 302-01-2 Sub-chronic toxicity (28 day): inhalation 15/07/2011 29/08/2011 Details
Cyclohexylidenebis[tert-butyl] peroxide 221-111-2 3006-86-8 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
Details
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide 221-088-9 3001-98-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details