Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 229-861-2 6790-58-5 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Fatty acids, tall-oil, reaction products with triethanolamine 267-053-1 67784-78-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
Details
Linseed oil, polymerized 614-114-9 67746-08-1 Reproductive toxicity (pre-natal developmental toxicity) 18/09/2014 03/11/2014 Details
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate 266-733-5 67584-55-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Bioaccumulation aquatic / sediment 01/04/2022 16/05/2022 Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Bioaccumulation aquatic / sediment 25/06/2019 09/08/2019 Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2011 15/08/2011 Details
1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol 266-587-2 67151-63-7 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine 229-761-9 6711-48-4 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) 22/09/2022 07/11/2022 Details
Dimethyl sulfoxide 200-664-3 67-68-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 31/01/2023 17/03/2023 Details
1,8-diazabicyclo[5.4.0]undec-7-ene 229-713-7 6674-22-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate 266-442-3 66669-53-2 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014 Details
4-methylthiosemicarbazide 229-563-2 6610-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
Docosan-1-ol 211-546-6 661-19-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/06/2023
30/06/2023
14/08/2023
14/08/2023
Details
Diphosphoric acid, compd. with piperazine (1:1) 457-330-7 66034-17-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
10/05/2022
27/06/2022
27/06/2022
27/06/2022
Details
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane 229-542-8 6600-31-3 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
Hexanal 200-624-5 66-25-1 Genetic toxicity in vivo “|| Note: Testing proposal is based on concern identified by the registrant.” 27/05/2019 11/07/2019 Details
Resin acids and Rosin acids, hydrogenated, esters with glycerol 266-042-9 65997-13-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, hydrogenated, esters with glycerol 266-042-9 65997-13-9
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
Resin acids and Rosin acids, polymd., esters with pentaerythritol 613-868-6 65997-12-8
Reproductive toxicity (pre-natal developmental toxicity), || Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details
Rosin, hydrogenated 266-041-3 65997-06-0
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
Rosin, hydrogenated 266-041-3 65997-06-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Rosin, oligomers 500-163-2 65997-05-9 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Rosin, fumarated 266-040-8 65997-04-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with the registered substance (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
06/03/2012
02/07/2013
02/07/2013
02/07/2013
20/04/2012
16/08/2013
16/08/2013
16/08/2013
Details
Slimes and Sludges, blast furnace and steelmaking 266-006-2 65996-73-8
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Slimes and Sludges, blast furnace and steelmaking 266-006-2 65996-73-8 Genetic toxicity in vivo||Note: testing proposed with Iron (EC no. 231-096-4), Calcium oxide (EC no. 215-138-9), Magnesium oxide (EC no. 215-171-9), Zinc (EC no. 231-175-3) and Manganese (EC no. 231-105-1) 30/06/2023 14/08/2023 Details
Dust, steelmaking 266-005-7 65996-72-7 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2011 15/08/2011 Details
Sodium toluene-4-sulphonate 211-522-5 657-84-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate 
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate 
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Details
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2015 16/11/2015 Details
sodium toluene-4-sulphonate 211-522-5 657-84-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) 16/12/2016 30/01/2017 Details
N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine 695-748-3 65286-55-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
[4-[p,p'-bis(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium m-[[p-anilinophenyl]azo]benzenesulphonate 265-449-9 65113-55-5
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
04/04/2014
Details
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt 229-390-2 6505-30-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Paraffins (petroleum), normal C>10 265-232-9 64771-71-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Solvent naphtha (petroleum), heavy arom. 265-198-5 64742-94-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Sub-chronic toxicity (90-day): oral || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
22/04/2021
22/04/2021
22/04/2021
07/06/2021
07/06/2021
07/06/2021
Details
Asphalt, oxidized 265-196-4 64742-93-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019 Details
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/02/2013
18/02/2013
04/04/2013
04/04/2013
Details
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Gas oils (petroleum), hydrodesulfurized light vacuum 265-190-1 64742-87-6
Genetic toxicity in vivo || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) 1st (Rat) and 2nd species (Rabbit) (Dermal route) || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with category members - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Gas oils (petroleum), hydrodesulfurized light vacuum 265-190-1 64742-87-6 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Residues (petroleum), hydrodesulfurized vacuum 265-188-0 64742-85-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
Reproductive toxicity (two-generation reproductive toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
04/04/2014
04/04/2014
19/05/2014
19/05/2014
Details
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9 Genetic toxicity in vivo 14/05/2020 29/06/2020 Details
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6 Genetic toxicity in vivo 14/05/2020 29/06/2020 Details
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7 Genetic toxicity in vivo 14/05/2020 29/06/2020 Details
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), residual oil solvent 265-110-5 64742-10-5 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
Extracts (petroleum), residual oil solvent 265-110-5 64742-10-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), residual oil solvent 265-110-5 64742-10-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 06/06/2023 21/07/2023 Details
Extracts (petroleum), heavy naphtha solvent 265-099-7 64741-98-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Reproductive toxicity (pre-natal developmental toxicity) || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
Sub-chronic toxicity (90-day): oral || Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)
22/04/2021
22/04/2021
22/04/2021
07/06/2021
07/06/2021
07/06/2021
Details
Distillates (petroleum), sweetened middle 265-088-7 64741-86-2 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), light hydrocracked 265-078-2 64741-77-1
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Distillates (petroleum), light hydrocracked 265-078-2 64741-77-1 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), light vacuum 265-059-9 64741-58-8
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
Sub-chronic toxicity (90-day): oral
07/07/2020
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Gas oils (petroleum), light vacuum 265-059-9 64741-58-8 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Residues (petroleum), vacuum 265-057-8 64741-56-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019 Details
Residues (petroleum), vacuum 265-057-8 64741-56-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Residues (petroleum), vacuum 265-057-8 64741-56-6
Genetic toxicity in vivo||Note: testing proposed with Asphalt (EC no. 232-490-9)
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Asphalt (EC no. 232-490-9)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Asphalt (EC no. 232-490-9)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Asphalt (EC no. 232-490-9)
04/12/2023
04/12/2023
04/12/2023
04/12/2023
18/01/2024
18/01/2024
18/01/2024
18/01/2024
Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Distillates (petroleum), straight-run middle 265-044-7 64741-44-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) 23/11/2020 07/01/2021 Details
Distillates (petroleum), straight-run middle 265-044-7 64741-44-2 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), straight-run 265-043-1 64741-43-1 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017 Details
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Tolyltriazole (EC 249-596-6) 16/12/2020 01/02/2021 Details
Poly [oxy(methyl-1,2-ethanediyl)] , a -hydro-w -hydroxy-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1), 3-[[3-dimethylamino) propyl]imino]butanoate 613-645-3 646505-36-4 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
Decamethylenediamine 211-471-9 646-25-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
Yttrium zirconium oxide 264-885-7 64417-98-7 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014 Details
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid. 613-584-2 64401-02-1 Genetic toxicity in vivo 03/02/2016 21/03/2016 Details
Esterification products of 4,4'-isopropylidenediphenol, ethoxylated and prop-2-enoic acid. 613-584-2 64401-02-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/11/2014
18/09/2014
02/01/2015
03/11/2014
Details
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol 264-848-5 64365-17-9
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol 264-848-5 64365-17-9 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate 229-208-1 6428-31-5 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine 264-761-2 64265-45-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant 21/01/2021 08/03/2021 Details
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine 264-761-2 64265-45-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. 25/05/2020 09/07/2020 Details
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate 264-513-3 63843-89-0 Genetic toxicity in vivo 29/04/2014 13/06/2014 Details
N,N,N',N'-tetrakis(2,3-epoxypropyl)-m-xylene-α,α'-diamine 264-438-6 63738-22-7 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020 12/03/2020 Details
1,1`-(1,1-dimethyl-3-methylene-1,3-propanediyl)bisbenzene 228-846-8 6362-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Sodium hydrogen-5-sulphoisophthalate 228-845-2 6362-79-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
22/04/2021
22/04/2021
07/06/2021
07/06/2021
Details
Sodium hydrogen-5-sulphoisophthalate 228-845-2 6362-79-4 Genetic toxicity in vivo 29/04/2014 13/06/2014 Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide 228-768-4 6358-31-2 7.5.2 Repeated dose toxicity: inhalation 08/03/2024 22/04/2024 Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2015 10/08/2015 Details
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0
(90-day): oral
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity
20/10/2010
20/10/2010
20/10/2010
06/12/2010
06/12/2010
06/12/2010
Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
2-[[(butylamino)carbonyl]oxy]ethyl acrylate 264-036-0 63225-53-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020 Details
Tris[4-(diethylamino)phenyl]methylium acetate 263-974-8 63157-72-2 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2011 29/08/2011 Details
Androst-4-ene-3,17-dione 200-554-5 63-05-8 Long-term toxicity to fish 21/01/2021 08/03/2021 Details
Hexadec-1-ene 211-105-8 629-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Details
Tetradecane 211-096-0 629-59-4 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Tridecane 211-093-4 629-50-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hexane-1,6-diol 211-074-0 629-11-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
30/06/2011
30/06/2011
Details