Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
2,2,4,4,6,8,8-heptamethylnonane 224-506-8 4390-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2) 02/11/2018 17/12/2018 Details
2,2,4-trimethylpentane-1,3-diol 205-619-1 144-19-4 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
2,2-Bis(hydroxymethyl)-1,3-propanediol (pentaerythritol) 204-104-9 115-77-5 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011 Details
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid 225-306-3 -
Reproductive toxicity (pre-natal developmental toxicity study)
Sub-chronic oral toxicity (90-day): oral
05/04/2011
05/04/2011
20/05/2011
20/05/2011
Details
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate 239-937-7 15834-04-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Details
2,2-dimethyl-3-oxopropyl acetate 811-188-6 16184-79-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 01/09/2017 16/10/2017 Details
2,2-dimethyl-3-oxopropyl dodecanoate 468-880-2 102985-93-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate 255-180-5 41026-17-9
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
30/06/2014
Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate  255-180-5 41026-17-9
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2016
16/12/2016
16/12/2016
30/01/2017
30/01/2017
30/01/2017
Details
2,2-dimethylpropane-1,3-diyl dibenzoate 224-081-9 4196-89-8 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016 Details
2,2`-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
2,2`-iminodi(ethylamine),N-(2-aminoethyl)ethane-1,2-diamine 203-865-4 111-40-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
05/04/2011
05/04/2011
05/04/2011
20/05/2011
20/05/2011
20/05/2011
Details
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide 686-241-8 81058-27-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
2,3-epoxypropyl isopropyl ether 223-672-9 4016-14-2 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
26/05/2010
26/05/2010
26/05/2010
12/07/2010
12/07/2010
12/07/2010
Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): dermal
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid 500-281-4 98362-33-5
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Details
2,3-epoxypropyl o-tolyl ether 218-645-3 2210-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
Details
2,4,4-trimethylpentene 246-690-9 25167-70-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018
Details
2,4,4-trimethylpentene 246-690-9 25167-70-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 15/07/2022 29/08/2022 Details
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
31/01/2018
31/01/2018
19/03/2018
19/03/2018


Details
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)
04/10/2013
04/10/2013
18/11/2013
18/11/2013
Details
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) 25/05/2020 09/07/2020 Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 219-863-1 2554-06-5
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
03/03/2014
03/03/2014
17/04/2014
17/04/2014
17/04/2014
17/04/2014
Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
2,4,6-tri-tert-butylphenol 211-989-5 732-26-3 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2021 16/08/2021 Details
2,4,6-triallyloxy-1,3,5-triazine 202-936-7 101-37-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
2,4,6-trinitrotoluene 204-289-6 118-96-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
04/04/2014
04/04/2014
04/04/2014
19/05/2014
19/05/2014
19/05/2014
Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 25713-60-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
Details
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated 500-022-5 9014-85-1 Reproductive toxicity (pre-natal developmental toxicity)

|| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) ||
25/11/2019 09/01/2020 Details
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt 286-344-4 85209-91-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- 485-230-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
Details
2,4-di-tert-butylphenol 202-532-0 96-76-4 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2,4-dihydroxybenzophenone 205-029-4 131-56-6 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol 411-220-5 - Reproductive toxicity (pre-natal developmental toxicity) 25/09/2012 12/11/2012 Details
2,4-Pentanedione, peroxide 253-384-9 37187-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Details
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone 212-990-3 903-19-5 Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
2,5-di-tert-pentylhydroquinone 201-222-2 79-74-3 Sub-chronic toxicity (90-day): oral 31/05/2011 15/07/2011 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details