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Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
chlorodimethylvinylsilane 217-007-1 1719-58-0 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) 12/12/2014 26/01/2015
Dichloro(methyl)(phenyl)silane 205-746-2 149-74-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) 04/04/2014 19/05/2014
dimethoxymethylsilane 240-914-9 16881-77-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014
triethoxy(methyl)silane 217-983-9 2031-67-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. 16/10/2014 01/12/2014
Benzenamine, N-phenyl-, reaction products with styrene and 2,4,4-trimethylpentene 272-940-1 68921-45-9
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the smallest aryl- and alkyl-substituted materials
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Resin acids and Rosin acids, calcium zinc salts 269-825-3 68334-35-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Resin acids and Rosin acids, sodium salts 263-144-5 61790-51-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts 273-527-9 68988-45-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
19/11/2018
19/11/2018
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) 247-810-2 26566-95-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"
04/10/2018
04/10/2018
19/11/2018
19/11/2018
Zinc bis[bis(dodecylphenyl)] bis(dithiophosphate) 259-048-8 54261-67-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
19/11/2018
19/11/2018


Phosphoric acid, mixed esters with Bu alc. and ethylene glycol 284-716-0 84962-20-9
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Nitroethane 201-188-9 79-24-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with nitromethane (EC 200-876-6) 10/03/2017 25/04/2017
Alkane-alpha,omega-diyl bis{[(trimethoxysilyl)propyl]carbamate}_M2 700-904-1 1350725-68-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl [3-(trimethoxysilyl) propyl]carbamate CAS 23432-62-4 02/11/2018 17/12/2018
orthoboric acid, compound with 2,2'-iminodiethanol 267-886-0 67952-33-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with MEA Polyborate
Sub-chronic toxicity (90-day): oral || Note: testing proposed with MEA Polyborate
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Octene 246-920-8 25377-83-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with hex-1-ene
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 701-120-2 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 614-339-2 68154-62-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (EC 500-191-5, CAS 68082-29-1)
16/10/2014
16/10/2014
01/12/2014
01/12/2014
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate
12/12/2014
12/12/2014
26/01/2015
26/01/2015
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
methyl-1h-benzotriazole 249-596-6 29385-43-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate 16/12/2016 30/01/2017
dichloro(diphenyl)silane 201-251-0 80-10-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
Sub-chronic toxicity (90-day): oral
Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane 241-867-7 17928-28-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with decamethyltetrasiloxane (EC no. 205-491-7, CAS no. 141-62-8) 12/12/2014 26/01/2015
diammonium hexanitratocerate 240-827-6 16774-21-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) 20/05/2015 06/07/2015
1,4-diisopropylbenzene 202-826-9 100-18-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS no. 99-62-7
Sub-chronic toxicity (90-day): oral || Note: testing proposed with CAS no. 99-62-7
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Sodium hydrogen N-(1-oxododecyl)-L-glutamate 249-958-3 29923-31-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS 68187-30-4 16/05/2014 30/06/2014
Trimethyl borate 204-468-9 121-43-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with boric acid.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with boric acid.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with boric acid.
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
bismuth citrate 212-390-1 813-93-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Bismuth trinitrate 233-791-8 10361-44-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
20/09/2013
20/09/2013
04/11/2013
04/11/2013
ethyl methyl carbonate 433-480-9 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
(octadecanoato-O)oxoaluminium 236-521-7 13419-15-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Aluminum, benzoate C16-18 fatty acid complexes (CAS 94166-87-7) 30/11/2015 14/01/2016
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid 500-090-6 36425-16-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a structurally related substance (small vinyl ester)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with a structurally related substance (small vinyl ester)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018
Pyridine, alkyl derivs. 269-929-9 68391-11-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 5-ethyl-2-methylpyridine 04/04/2014 19/05/2014
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
2-Oxepanone, polymer with 1,6-hexanediol 609-271-5 36609-29-7
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol
16/10/2014
16/10/2014
01/12/2014
01/12/2014
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 10/08/2018 24/09/2018
Nonanoic acid (branched), 2-oxiranylmethyl ester 940-029-4 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
20/09/2013
20/09/2013
20/09/2013
04/11/2013
04/11/2013
04/11/2013
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017
(3-chloropropyl)diethoxymethylsilane 236-828-6 13501-76-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with (3-chloropropyl)triethoxysilane (CAS 5089-70-3) 17/04/2015 04/06/2015
Resin acids and Rosin acids, Me esters 269-035-9 68186-14-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed on rabbits 14/08/2014 28/09/2014
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated 614-503-3 68441-62-3
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed on rabbit.
Reproductive toxicity (two-generation reproductive toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt 939-513-8 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
Sub-chronic toxicity (90-day): oral
Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
25/06/2015
25/06/2015
10/08/2015
10/08/2015
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant.
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate 908-996-7 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).
Sub-chronic toxicity (90-day): oral || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).
20/05/2015
20/05/2015
06/07/2015
06/07/2015
Residues (petroleum), hydrodesulfurized vacuum 265-188-0 64742-85-4
Reproductive toxicity (pre-natal developmental toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
Reproductive toxicity (two-generation reproductive toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
04/04/2014
04/04/2014
19/05/2014
19/05/2014
Dihexadecyl peroxodicarbonate 247-611-0 26322-14-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
07/06/2018
07/06/2018
Reaction products of acrylic acid with 2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] 830-217-3 1393932-71-2
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated
24/01/2019
24/01/2019
11/03/2019
11/03/2019
1,4-Cyclohexanedimethanol, reaction products with epichlorohydrin 600-447-7 1035218-79-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated
Sub-chronic toxicity (90 day): inhalation || Note: Link to registration dossier not given as the dossier not yet disseminated
23/12/2015
23/12/2015
03/02/2016
03/02/2016
Hexamethyldisiloxane 203-492-7 107-46-0 Reproductive toxicity (pre-natal developmental toxicity) with the rabbit via inhalation 25/06/2019 09/08/2019
Sodium diisobutyldithiophosphinate 236-419-2 13360-78-6
Reproductive toxicity (pre-natal developmental toxicity) with Rat
Sub-chronic toxicity (90-day): oral
24/07/2019
24/07/2019
09/09/2019
09/09/2019
1,3,5-tris[[4-tert-butyl-3-hydroxy-2,6-xylyl]methyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 254-996-9 40601-76-1 Reproductive toxicity (pre-natal developmental toxicity) with Rat 24/07/2019 09/09/2019
Strontium neodecanoate 812-724-1 106705-37-7 Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Strontium oxide] (EC 215-219-9) 26/04/2019 10/06/2019
triethoxy(phenyl)silane 212-305-8 780-69-8 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1)
25/06/2015 10/08/2015
trichloro(hexadecyl)silane 227-575-2 5894-60-0
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)
Sub-chronic toxicity (90-day): oral
Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
dodecamethylpentasiloxane 205-492-2 141-63-9 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7).
25/06/2015 10/08/2015
butan-2-one O,O',O''-(vinylsilylidyne)trioxime 218-747-8 2224-33-1 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).
25/06/2015 10/08/2015
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine 245-642-4 23410-40-4
Reproductive toxicity (pre-natal developmental toxicity)
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
Sub-chronic toxicity (90-day): oral
Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with triethylenetetramine 500-290-3 103758-99-2
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Fatty acids, tall oil and rosin reacted with maleic anhydride 940-281-5 -
Reproductive toxicity (pre-natal developmental toxicity) //Note:testing to be done with rosin maleated (CAS 8050-28-0)
Sub-chronic toxicity (90-day): oral. //Note:testing to be done with rosin maleated (CAS 8050-28-0)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Rosin, fumarated, reaction products with formaldehyde 305-795-0 95009-65-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0).
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Resin acids and Rosin acids, maleated, calcium salts 294-402-5 91722-01-9
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Rosin, maleated 232-480-4 8050-28-0
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and the registered substance
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Fatty acids, tall oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts, consisting of mainly calcium, magnesium, zinc salts of maleated rosin, fatty acids and rosin 500-451-8 160901-14-4
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Resin acids and Rosin acids, esters with triethylene glycol 232-478-3 8050-25-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Resin acids and Rosin acids, maleated, sodium salts 269-228-8 68201-60-5
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Rosin, reaction products with formaldehyde 293-659-0 91081-53-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Rosin (CAS RN 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with _ Rosin (CAS RN 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)
19/07/2013
02/07/2013
02/07/2013
02/09/2013
16/08/2013
16/08/2013
Rosin, hydrogenated 266-041-3 65997-06-0
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Resin acids and Rosin acids, maleated, esters with pentaerythritol 305-516-2 94581-17-6
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Rosin, fumarated, reaction products with glycerol and pentaerythritol 296-047-1 92202-14-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS 97489-11-7); Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4); and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS 94581-17-6)
19/07/2013
19/07/2013
02/07/2013
19/07/2013
02/07/2013
02/09/2013
02/09/2013
16/08/2013
02/09/2013
16/08/2013
Resin acids and Rosin acids, fumarated, esters with pentaerythritol 305-514-1 94581-15-4
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7)
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
02/07/2013
02/07/2013
19/07/2013
19/07/2013
02/07/2013
02/09/2013
16/08/2013
16/08/2013
02/09/2013
02/09/2013
16/08/2013
Alkenes, C20-24 alpha 700-962-8 -
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)
22/10/2013
22/10/2013
05/12/2013
05/12/2013
Resin acids and Rosin acids, hydrogenated, esters with glycerol 266-042-9 65997-13-9
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Trichloro(propyl)silane 205-489-6 141-57-1 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Triethoxy(propyl)silane (EC 219-842-7, CAS 2550-02-9) 04/04/2014 19/05/2014
Decene, hydroformylation products, high boiling 935-454-7 -
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane 915-748-1 -
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6)
Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6)
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 16/05/2014 30/06/2014
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 21/03/2014 05/05/2014
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters 701-257-8 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5) 10/08/2018 24/09/2018
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid 806-510-7 1393571-43-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
N-(dimethylvinylsilyl)-1,1-dimethyl-1-vinylsilylamine 231-701-1 7691-02-3
Reproductive toxicity (pre-natal developmental toxicity) “|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)”
Sub-chronic toxicity (90 day): inhalation “|| Note: Testing proposed with hexamethyldisilazane (CAS 999-97-3)”
12/12/2014
12/12/2014
26/01/2015
26/01/2015
Methylphosphonic acid 213-607-2 993-13-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1)
30/11/2015
30/11/2015
14/01/2016
14/01/2016
methylsilanetriyl triacetate 224-221-9 4253-34-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) 16/03/2015 30/04/2015
dichlorocyclohexylmethylsilane 226-956-0 5578-42-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) 16/03/2015 30/04/2015
2-amino-2-ethylpropanediol 204-101-2 115-70-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Trometamol 201-064-4 77-86-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-amino-1,3-propanediol
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-amino-1,3-propanediol
17/06/2014
17/06/2014
01/08/2014
01/08/2014
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) 939-448-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
02/06/2014
02/06/2014
17/07/2014
17/07/2014
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” 17/04/2015 04/06/2015
Reaction mass of trans-Cyclohexadecen-8-one, cis-Cyclohexadecen-8-one, trans-Cyclohexadecen-7-one, cis-Cyclohexadecen-7-one 448-300-4 88642-03-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
tripotassium propylsilanetriolate 299-135-8 93857-00-2
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
16/03/2015
16/03/2015
30/04/2015
30/04/2015
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione 258-904-8 53988-10-6
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine 221-336-6 3069-29-2
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.
25/06/2015
25/06/2015
10/08/2015
10/08/2015
1,1,1,3,5,5,5-heptamethyltrisiloxane 217-496-1 1873-88-7
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7
Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7.
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 27/05/2019 11/07/2019
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed 941-809-7 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
(-)-pin-2(3)-ene 232-077-3 7785-26-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014
(ethoxymethoxy)cyclododecane 261-332-1 58567-11-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
(no public substance name available) 916-916-7 - Reproductive toxicity (pre-natal developmental toxicity) 12/12/2014 26/01/2015
(phenylethyl)benzene 254-179-7 38888-98-1 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated 926-000-9 - Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014
(Z)-N-octadec-9-enylhexadecan-1-amide 240-367-6 16260-09-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1,1'-dithiobis[hexahydro-2H-azepin-2-one] 245-910-0 23847-08-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol 204-137-9 116-37-0 Reproductive toxicity (pre-natal developmental toxicity) 31/07/2015 14/09/2015
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate 244-894-2 22288-43-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014
1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 213-834-7 1025-15-6 Reproductive toxicity (pre-natal developmental toxicity) 25/09/2012 12/11/2012
1,3- and 1,4-cyclohexandicarboxyaldehyde 482-020-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone 255-460-7 41611-76-1 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014
1,4-diazabicyclooctane 205-999-9 280-57-9 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
1-aminopropan-2-ol 201-162-7 78-96-6 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
1-chloro-2,3-dimethylbenzene 480-880-4 608-23-1 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
1-Dodecene, dimers 814-509-8 62132-67-6 Reproductive toxicity (pre-natal developmental toxicity) 02/11/2018 17/12/2018
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate 229-934-9 6846-50-0 Reproductive toxicity (pre-natal developmental toxicity) 14/03/2016 28/04/2016
2,2'-(cyclohexylimino)bisethanol 224-809-5 4500-29-2 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1 Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016
2,2,2`,2`-Tetrakis(hydroxymethyl)-3,3`-oxydipropan-1-ol 204-794-1 126-58-9 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011
2,2,4-trimethylpentane-1,3-diol 205-619-1 144-19-4 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014
2,2-Bis(hydroxymethyl)-1,3-propanediol (pentaerythritol) 204-104-9 115-77-5 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
2,2-dimethylpropane-1,3-diyl dibenzoate 224-081-9 4196-89-8 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol 411-220-5 - Reproductive toxicity (pre-natal developmental toxicity) 25/09/2012 12/11/2012
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018
2-(2-methoxyethoxy)ethanol 203-906-6 111-77-3 Reproductive toxicity (pre-natal developmental toxicity) 21/10/2019 05/12/2019
2-(dimethylamino)-2-methylpropan-1-ol 230-279-6 7005-47-2 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol 608-744-3 32472-85-8 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 - Reproductive toxicity (pre-natal developmental toxicity) 24/05/2013 08/07/2013
2-mercaptoethanol 200-464-6 60-24-2 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol 500-099-5 37625-56-2 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2011 29/08/2011
2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine 601-101-8 111497-86-0 Reproductive toxicity (pre-natal developmental toxicity) 02/06/2014 17/07/2014
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019
2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid 700-002-8 - Reproductive toxicity (pre-natal developmental toxicity) 16/07/2012 30/08/2012
3,7-dimethyloct-6-enenitrile 257-288-8 51566-62-2 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014
3,7-dimethyloctan-1-ol 203-374-5 106-21-8 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane 229-542-8 6600-31-3 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one 241-753-7 17772-51-9 Reproductive toxicity (pre-natal developmental toxicity) 31/08/2015 15/10/2015
3-Pentanone, 1,1,1,2,2,4,5,5-nonafluoro-4-(trifluoromethyl )- 436-710-6 756-13-8 Reproductive toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0 Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019
3a,4,7,7a-tetrahydro-4,7-methanoindene 201-052-9 77-73-6 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2019 15/04/2019
4'-hydroxyacetophenone 202-802-8 99-93-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Reproductive toxicity (pre-natal developmental toxicity) 06/09/2018 22/10/2018
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, esters with acrylic acid 500-130-2 55818-57-0 Reproductive toxicity (pre-natal developmental toxicity) 31/05/2016 15/07/2016
5-methylhexan-2-one 203-737-8 110-12-3 Reproductive toxicity (pre-natal developmental toxicity) 14/02/2011 31/03/2011
6,15-dihydroanthrazine-5,9,14,18-tetrone 201-375-5 81-77-6 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) 701-138-0 242482-67-3 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
6-[(1-oxomethyloctyl)amino]hexanoic acid 276-173-3 71902-23-3 Reproductive toxicity (pre-natal developmental toxicity) 10/03/2017 25/04/2017
6-methyl-1,3,5-triazine-2,4-diyldiamine 208-796-3 542-02-9 Reproductive toxicity (pre-natal developmental toxicity) 21/03/2014 05/05/2014
8,9,10,11-tetrachloro-12H-phthaloperin-12-one 244-007-9 20749-68-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) 400-830-7 - Reproductive toxicity (pre-natal developmental toxicity) 16/12/2011 30/01/2012
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019
Aluminum, benzoate C16-18-fatty acids complexes 303-385-6 94166-87-7 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015
Amines, C16-22-alkyl 268-215-4 68037-92-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Anisole 202-876-1 100-66-3 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014
Aromatic hydrocarbons, C10-13, reaction products with branched nonene, sulfonated, sodium salts 800-660-7 1258274-08-6 Reproductive toxicity (pre-natal developmental toxicity) 23/01/2015 09/03/2015
Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests) 931-257-5 - Reproductive toxicity (pre-natal developmental toxicity) 05/04/2011 20/05/2011
Benzotriazole 202-394-1 95-14-7 Reproductive toxicity (pre-natal developmental toxicity) 22/10/2013 05/12/2013
Benzyldimethylamine 203-149-1 103-83-3 Reproductive toxicity (pre-natal developmental toxicity) 15/09/2011 31/10/2011
Benzyltoluene 248-654-8 27776-01-8 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014
benzyltrimethylammonium chloride 200-300-3 56-93-9 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018
Bis(2-ethylhexyl) tetrabromophthalate 247-426-5 26040-51-7 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts 939-691-7 - Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
cerium trinitrate 233-297-2 10108-73-3 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011
Copolymer of benzenamine and formaldehyde, hydrogenated 603-894-6 135108-88-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014
Copper hydroxide nitrate 439-590-3 12158-75-7 Reproductive toxicity (pre-natal developmental toxicity) 03/11/2011 19/12/2011
Cyclohexane-1,4-dicarboxylic acid 214-068-6 1076-97-7 Reproductive toxicity (pre-natal developmental toxicity) 27/11/2013 10/01/2014
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts 609-542-8 383178-66-3 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016
d-Glucose, ether with glycerol 309-496-6 100402-60-6 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014
Decamethylcyclopentasiloxane 208-764-9 541-02-6 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017
Decamethylenediamine 211-471-9 646-25-3 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014
decamethyltetrasiloxane 205-491-7 141-62-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2011 15/08/2011
Dibenzoyl peroxide 202-327-6 94-36-0 Reproductive toxicity (pre-natal developmental toxicity) 16/06/2011 01/08/2011
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 15/09/2011 31/10/2011
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
Diethylmethylbenzenediamine 270-877-4 68479-98-1 Reproductive toxicity (pre-natal developmental toxicity) 29/07/2011 12/09/2011
dihydro-3-(tripropenyl)furan-2,5-dione 295-556-6 92077-08-2 Reproductive toxicity (pre-natal developmental toxicity) 30/09/2015 16/11/2015
Dimethyl cyclohexane-1,4-dicarboxylate 202-347-5 94-60-0 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014
Diphenyl sulphone 204-853-1 127-63-9 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide 278-355-8 75980-60-8 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014
Disodium oxybis[methylbenzenesulphonate] 277-242-0 73037-34-0 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2014 01/08/2014
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017
Dust, steelmaking 266-005-7 65996-72-7 Reproductive toxicity (pre-natal developmental toxicity) 01/07/2011 15/08/2011
Ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate] 251-073-2 32509-66-3 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2014 17/03/2014
Fatty acids, C16-18 and C18-unsatd., branched and linear, reaction products with diethylenetriamine and tall-oil fatty acids, Me maleates 806-509-1 1393571-42-0 Reproductive toxicity (pre-natal developmental toxicity) 05/06/2014 21/07/2014
Fatty acids, C16-18, reaction products with diethanolamine 293-014-3 91032-08-5 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized 605-143-8 158318-67-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized, reaction products with ethylen glycol 606-712-3 211450-54-3 Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018
Fatty acids, tall-oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts 500-451-8 160901-14-4 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012



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