Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Ethane- 1,2-diol, propoxylated | 500-078-0 | 31923-84-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-070-7 | 30583-72-3 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
Tetrakis(hydroxymethyl)phosphonium chloride, oligomeric reaction products with urea | 500-057-6 | 27104-30-9 | Sub-chronic toxicity (90-day): oral | 02/09/2011 | 17/10/2011 | Details | |
Propylidynetrimethanol, propoxylated | 500-041-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
4,4'-Methylenediphenyl diisocyanate, oligomers | 500-040-3 | 25686-28-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated | 500-022-5 | 9014-85-1 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) || |
25/11/2019 | 09/01/2020 | Details | |
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- | 500-012-0 | 9004-77-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1). Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) | 500-004-7 | 9003-29-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- | 485-230-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
(E)-N-(pentan-2-ylidene)hydroxylamine | 484-470-6 | 623-40-5 | Reproductive toxicity (pre-natal developmental toxicity) | 18/03/2021 | 03/05/2021 | Details | |
N-pentan-2-ylidenehydroxylamine | 484-470-6 | 623-40-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/05/2021 20/05/2021 |
05/07/2021 05/07/2021 |
Details | |
Pentaerythritol, reaction product with fatty acids, C8 to 18 (even numbered) and/or branched and/or unsaturated | 484-420-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/04/2012 | 14/06/2012 | Details | |
Reaction products of Fatty acids, C16-18 and C18-unsatd. and reaction mass of 1,3-alkanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-heteromonocycle-5,5-dimethanol | 484-360-8 | 98859-60-0 | Reproductive toxicity (pre-natal developmental toxicity) | 17/08/2012 | 01/10/2012 | Details | |
Everzol Red CDN Crude | 483-940-8 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 31/01/2018 | 19/03/2018 | Details | |
4-fluoro-1,3-dioxolan-2-one | 483-360-5 | 114435-02-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |
3-amino-4-octanol | 482-070-6 | 1001354-72-8 | Reproductive toxicity (developmental toxicity) | 19/11/2010 | 03/01/2011 | Details | |
1,3- and 1,4-cyclohexandicarboxyaldehyde | 482-020-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
C8-C26 branched and linear hydrocarbons - Distillates | 481-740-5 | 848301-67-7 | Bioaccumulation aquatic / sediment | 11/05/2010 | 25/06/2010 | Details | |
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt | 480-890-9 | 906532-68-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 18/11/2014 | 02/01/2015 | Details | |
1-chloro-2,3-dimethylbenzene | 480-880-4 | 608-23-1 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
4-((Triethoxysilyl)methyl) morpholine | 480-370-1 | 21743-27-1 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
27/11/2009 27/11/2009 27/11/2009 |
11/01/2010 11/01/2010 11/01/2010 |
Details | |
1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane | 479-930-8 | 613222-52-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
N-(2-nitrophenyl)phosphoric triamide | 477-690-9 | - | Long-term toxicity to fish | 18/03/2021 | 03/05/2021 | Details | |
LiFePO4 | 476-700-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 22/10/2013 | 05/12/2013 | Details | |
Reaction product Formaldehyde, amine and phenol | 476-290-1 | - | Genetic toxicity in vivo | 15/08/2013 | 30/09/2013 | Details | |
tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate | 474-870-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
Reaction mass of 1-(1-Methyl-2-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-2-ol and 1-(2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)propoxy)-propan-2-ol and 2-(2-(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yloxy]-propoxy)-propan-1-ol and 2-(1-Methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-1-ol | 470-680-5 | 958872-63-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-days): oral |
21/01/2011 21/01/2011 |
07/03/2011 07/03/2011 |
Details | |
2,2-dimethyl-3-oxopropyl dodecanoate | 468-880-2 | 102985-93-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester | 468-880-2 | 102985-93-3 | Long-term toxicity to fish | 30/09/2021 | 15/11/2021 | Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
Diphosphoric acid, compd. with piperazine (1:1) | 457-330-7 | 66034-17-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
Tetraammineplatinum (II) diacetate | 457-310-8 | - | Genetic toxicity in vivo (COMET, OECD TG 489) || Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9). | 22/06/2017 | 07/08/2017 | Details | |
5-Methoxy-2-tetralone | 457-080-9 | - | Genetic toxicity in vivo | 06/09/2018 | 22/10/2018 | Details | |
Lithium bis(oxalato)borate | 456-990-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
2-(2-Vinyloxyethoxy)ethyl acrylate | 451-690-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 |
Details | |
2,4,7,9-tetramethyl-4,7-decanediol | 451-160-7 | 17913-76-7 |
Long-term toxicity to fish "|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity) |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
Poly-(1,4-diisopropylbenzol) | 449-400-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Ureidopropyltrialkoxysilane | 449-160-7 | 116912-64-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction mass of trans-Cyclohexadecen-8-one, cis-Cyclohexadecen-8-one, trans-Cyclohexadecen-7-one, cis-Cyclohexadecen-7-one | 448-300-4 | 88642-03-9 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine | 447-920-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/05/2018 | 05/07/2018 | Details | |
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol | 446-990-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/01/2015 23/01/2015 |
09/03/2015 09/03/2015 |
Details | |
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs. | 445-790-1 | - | Sub-chronic toxicity (90 day): inhalation | 04/04/2014 | 19/05/2014 | Details | |
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl | 445-760-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/07/2015 31/07/2015 |
14/09/2015 14/09/2015 |
Details | |
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt | 445-040-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate | 443-860-6 | 302776-68-7 | Long-term toxicity to fish | 16/08/2011 | 30/09/2011 | Details | |