Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol | 939-071-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
Reaction mass of 4-tert-butylphenyl diphenyl phosphate and bis(4-tert-butylphenyl) phenyl phosphate and triphenyl phosphate | 700-990-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt | 445-040-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate | 946-378-9 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- | 911-811-2 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt | 939-513-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction mass of Alkenes C20-24 and Alkenes C24-28 | 931-746-3 | 93924-10-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/11/2011 03/11/2011 16/07/2012 |
19/12/2011 19/12/2011 30/08/2012 |
Details | |
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated | 932-164-2 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs. | 915-790-0 | - | Sub-chronic toxicity (90-day): oral | 12/12/2014 | 26/01/2015 | Details | |
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form | 939-559-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
Reaction mass of Benzeneacetic acid, alpha-oxo-, 1,1'-(oxydi-2,1-ethanediyl) ester and Benzeneacetic acid, alpha-oxo-, 2-(2-hydroxyethoxy)ethyl ester | 442-300-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2013 | 18/11/2013 | Details | |
Reaction Mass of Benzyl (1R,1S) 2,2,4-trimethyl-1-[(2-methylpropanoyl)oxy]pentan-3-yl benzene-1,2-dicarboxylate and Benzyl (3R,3S) 2,2,4-trimethyl-3-[(2-methylpropanoyl)oxy]pentyl benzene-1,2-dicarboxylate | 701-008-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate | 905-983-8 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Reaction mass of Bis(1,2,2,6,6-pentamethyl-4-piperidyl) sebacate and Methyl 1,2,2,6,6-pentamethyl-4-piperidyl sebacate | 915-687-0 | - | Genetic toxicity in vivo | 15/09/2011 | 31/10/2011 | Details | |
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane | 406-750-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
04/06/2012 04/06/2012 |
19/07/2012 19/07/2012 |
Details | |
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate | 940-592-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate | 931-536-1 | - | Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
Reaction mass of butane-2,2-diyl dihydroperoxide and di-sec-butylhexaoxidane | 700-954-4 | 1338-23-4 | Sub-chronic toxicity (90-day): oral | 19/12/2013 | 03/02/2014 | Details | |
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) | 943-172-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/05/2016 17/05/2016 17/05/2016 |
01/07/2016 01/07/2016 01/07/2016 |
Details | |
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol | 939-719-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction mass of cobalt and copper and iron | 912-664-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Reaction mass of cobalt sulphide and nickel sulphide and trinickel disulphide | 910-663-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Reaction mass of dibutyl adipate and dibutyl glutarate | 936-196-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate | 907-870-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) ||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate | 911-351-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate | 950-225-1 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) |
17/12/2019 17/12/2019 |
31/01/2020 31/01/2020 |
Details | |
Reaction mass of dipotassium 3,3'-sulphonylbis(benzenesulphonate) and potassium 3-(phenylsulphonyl)benzenesulphonate | 915-932-1 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride | 947-115-0 | - | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Reaction mass of Disodium dihydroxy[3-(hydroxy-kO)-4-{[5-(hydroxy-kO)-3-methyl-1-phenyl-1Hpyrazol-4-yl]diazenyl-kN1}naphthalene-1-sulfonato(3-)]chromate(2-) and sodium [4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxynaphthalene-1-sulphonato(3-)]hydroxychromate(1-) | 944-272-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate | - | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity study (90-day): oral |
13/12/2010 13/12/2010 |
27/01/2011 27/01/2011 |
Details | |
Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride | 951-974-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) | 23/11/2020 | 07/01/2021 | Details | |
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - | Long-term toxicity to fish | 25/11/2019 | 09/01/2020 | Details | |
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
Reaction mass of hydrogenated and dehydrogenated rosin | 911-238-8 | - |
Reproductive toxicity (pre-natal developmental toxicity)|| Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Reproductive toxicity (two-generation reproductive toxicity) || Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate | 908-996-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). Sub-chronic toxicity (90-day): oral || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
Reaction mass of N,N,N',N'-tetrabutylmethylenediamine and dibutylamine | 948-040-6 | - | Genetic toxicity in vivo || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: Testing proposal is based on concern identified by the registrant. | 24/01/2019 | 11/03/2019 | Details | |
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid | 934-058-1 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide | 943-947-3 | - | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- | 907-495-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit Sub-chronic toxicity (90 day): inhalation |
27/05/2019 27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 11/07/2019 |
Details | |
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene | 931-893-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Reaction mass of Poly(oxy-1,2-ethanediyl), ?-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-?-hydroxy-, mono-C13-15-alkyl ethers (odd numbered, branched and linear)-alkylethers, Acetamide, 2-(C13-15 (odd numbered, branched and linear)-alkyloxy)-N-(2-hydroxyethyl)- and Alcohols, C13-15-branched and linear | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/08/2011 | 30/09/2011 | Details | |
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate | 939-595-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol | 904-153-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-657-7 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-568-3 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/08/2013 |
Details | |
Reaction mass of Rosin, hydrogenated and [1R-(1a,4ß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid | 911-238-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate | 911-616-2 | - | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid | 939-201-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
Reaction mass of Sodiumbis[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodium [1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)][1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodiumbis[1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) | 915-756-5 | - | Genetic toxicity in vivo | 21/12/2021 | 04/02/2022 | Details | |
Reaction mass of trans-Cyclohexadecen-8-one, cis-Cyclohexadecen-8-one, trans-Cyclohexadecen-7-one, cis-Cyclohexadecen-7-one | 448-300-4 | 88642-03-9 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |