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Predchádzajúce/výsledok

Predchádzajúce/výsledok

Predchádzajúce/výsledok

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

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Strana 2 z 11
200 Položiek na stránku
Zobrazuje sa 201 - 400 z 2 011 výsledkov.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Decane 204-686-4 124-18-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
diethyl ether 200-467-2 60-29-7 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Diisopropyl ether 203-560-6 108-20-3 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Distillates (petroleum), full-range straight-run middle 272-341-5 68814-87-9 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), heavy straight-run 272-817-2 68915-96-8 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), light hydrocracked 265-078-2 64741-77-1 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), straight-run middle 265-044-7 64741-44-2 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Distillates (petroleum), sweetened middle 265-088-7 64741-86-2 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Dodecane 203-967-9 112-40-3 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18 unsatd. fatty acids, chlorides - 1079184-43-2 Reproductive toxicity (two-generation reproductive toxicity) 26/04/2010 10/06/2010 Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Extracts (petroleum), residual oil solvent 265-110-5 64742-10-5 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
Fuel oil, no. 2 270-671-4 68476-30-2 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Fuel oil, no. 4 270-673-5 68476-31-3 Reproductive toxicity (two-generation reproductive toxicity) 16/08/2011 30/09/2011 Details
Fuels, diesel 269-822-7 68334-30-5 Reproductive toxicity (two-generation reproductive toxicity) 16/08/2011 30/09/2011 Details
Fuels, diesel, no. 2 270-676-1 68476-34-6 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), hydrodesulfurized light vacuum 265-190-1 64742-87-6 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), hydrotreated light vacuum 295-407-5 92045-24-4 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Gas oils (petroleum), light vacuum 265-059-9 64741-58-8 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), straight-run 265-043-1 64741-43-1 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils (petroleum), straight-run, high-boiling 272-818-8 68915-97-9 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Gas oils, paraffinic 300-227-8 93924-33-5 Reproductive toxicity (two-generation reproductive toxicity) 02/09/2011 17/10/2011 Details
Geraniol 203-377-1 106-24-1 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011 Details
Hydrocarbons, C10-C12, isoalkanes, < 2% aromatics 923-037-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, isoalkanes, cyclics, <2% aromatics 918-317-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, <2% aromatics 929-018-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, < 2% aromatics 918-481-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C14, n-alkanes, isoalkanes, <2% aromatics 920-274-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C12, isoalkanes, < 2% aromatics 918-167-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C12, isoalkanes, cyclics, <2% aromatics 931-121-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C13, isoalkanes, <2% aromatics 920-901-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, isoalkanes, cyclics, <2% aromatics 927-285-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, n-alkanes, <2% aromatics 924-803-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics 926-141-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 925-653-7 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics 920-107-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics 927-676-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics 917-488-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics 918-973-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, < 2% aromatics 921-050-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics 928-253-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics 917-828-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics 927-632-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 920-360-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C20, n-alkanes, isoalkanes, <2% aromatics 931-265-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, <2% aromatics 919-029-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C17-C19, n-alkanes, <2% aromatics 937-158-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., tetraisobutylene fraction, hydrogenated 297-628-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated 297-629-8 93685-81-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C8-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 928-136-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, <2% aromatics 927-241-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 927-344-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, cyclics, <2% aromatics 925-894-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, isoalkanes, cyclics, <2% aromatics 920-134-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics 919-857-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-446-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Itaconic acid 202-599-6 - Reproductive toxicity (two-generation reproductive toxicity) 16/01/2012 01/03/2012 Details
Lithium carbonate 209-062-5 554-13-2 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Lithium chloride 231-212-3 7447-41-8 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Lithium hydroxide 215-183-4 1310-65-2 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Middle distillate from refinery proces cofeeding vegetable oil 938-793-9 - Reproductive toxicity (two-generation reproductive toxicity) 02/09/2013 18/10/2013 Details
Nonylphenol, branched, ethoxylated 500-209-1 68412-54-4 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Paraffins (petroleum), normal C>10 265-232-9 64771-71-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Pentan-3-one 202-490-3 96-22-0 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Potassium cyanate 209-676-3 590-28-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011 Details
Potassium permanganate 231-760-3 7722-64-7 Reproductive toxicity (two-generation reproductive toxicity) 14/02/2011 31/03/2011 Details
Raffinates (Fischer-Tropsch), C10-25-branched - 1345668-40-7 Reproductive toxicity (two-generation reproductive toxicity) 17/08/2012 01/10/2012 Details
Sodium chloroacetate 223-498-3 3926-62-3 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Sodium trichloroacetate, TCA 211-479-2 650-51-1 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Sodium xylenesulphonate 215-090-9 1300-72-7 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2014 29/08/2014 Details
Tetradecane 211-096-0 629-59-4 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Tetrahydrothiophene 1,1-dioxide 204-783-1 126-33-0 Reproductive toxicity (two-generation reproductive toxicity) 29/04/2011 14/06/2011 Details
Trichloroacetic acid 200-927-2 76-03-9 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Tridecane 211-093-4 629-50-5 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
tris(2-butoxyethyl) phosphate 201-122-9 78-51-3 Reproductive toxicity (two-generation reproductive toxicity) 01/07/2011 15/08/2011 Details
Undecane 214-300-6 1120-21-4 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Vinyl 2-ethylhexanoate 202-297-4 94-04-2 Reproductive toxicity (two-generation reproductive toxicity) 14/10/2011 28/11/2011 Details
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes 700-497-0 -
Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/11/2010
25/06/2012
03/01/2011
09/08/2012
 Details
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
 Details
[No public or meaningful name is available] 944-258-0 1850357-57-1 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) 03/05/2023 19/06/2023 Details
Neodecanoic acid, cobalt salt 248-373-0 27253-31-2 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) 28/11/2022 12/01/2023 Details
Resin acids and Rosin acids, cobalt salts 273-321-9 68956-82-1 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) 28/11/2022 12/01/2023 Details
Stearic acid, cobalt salt 237-016-4 13586-84-0 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) 28/11/2022 12/01/2023 Details
Reaction mass of 3-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde and 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde 915-650-9 -
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8)
04/09/2023
04/09/2023
19/10/2023
19/10/2023
 Details
Slags, silicomanganese-manufg. 273-733-9 69012-33-5 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Slags, ferromanganese-manufg. CAS No 69012-28-8 (EC No 273-728-1) 25/10/2017 11/12/2017 Details
Resin acids and Rosin acids, magnesium salts 270-461-2 68440-56-2
Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
dichloro(3-chloropropyl)methylsilane 232-136-3 7787-93-1 Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3) 16/10/2014 01/12/2014 Details
Resin acids and Rosin acids, potassium salts 263-142-4 61790-50-9
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed with Rosin (CAS 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin (CAS 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS 8050-09-7); Rosin, hydrogenated (CAS 65997-06-0); and Rosin, reaction products with formaldehyde (CAS 91081-53-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, esters with glycerol 232-482-5 8050-31-5
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7), Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, hydrogenated, esters with triethylene glycol 271-996-4 68648-53-3
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol 264-848-5 64365-17-9
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Reaction mass of hydrogenated and dehydrogenated rosin 911-238-8 -
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
 Details
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide 919-846-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with an analogous substance
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
 Details
Saccharomyces cerevisiae cell wall, extracted 949-711-6 -
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
 Details
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) 947-369-2 -
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
 Details
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity)
1st and 2nd PNDTs: || Note: testing proposed with 2-92-92-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 		27/01/2020 12/03/2020 Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity):
1st PNDT on the registered substance
2nd PNDT with the registered substance
// Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6) 		27/01/2020 12/03/2020 Details
Resin acids and Rosin acids, esters with diethylene glycol 268-884-2 68153-38-8
Reproductive toxicity (pre-natal developmental toxicity), || Note: testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, polymd., esters with glycerol 614-523-2 68475-37-6
Reproductive toxicity (pre-natal developmental toxicity), || Note: testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, polymd., esters with pentaerythritol 613-868-6 65997-12-8
Reproductive toxicity (pre-natal developmental toxicity), || Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
 Details
Trimethylolpropane Diallyl Ether / 2,2-bis(allyloxymethyl)butan-1-ol / 2,2-bis[(allyloxy)methyl]butan-1-ol 211-661-1 682-09-7
Reproductive toxicity (pre-natal developmental toxicity)
subchronic toxicity (90-day)
26/01/2011
26/01/2011
14/03/2011
14/03/2011
 Details
Reaction mass of 1-(1-Methyl-2-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-2-ol and 1-(2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)propoxy)-propan-2-ol and 2-(2-(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yloxy]-propoxy)-propan-1-ol and 2-(1-Methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-1-ol 470-680-5 958872-63-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-days): oral
21/01/2011
21/01/2011
07/03/2011
07/03/2011
 Details
Resin acids and Rosin acids, fumarated, esters with glycerol 307-051-0 97489-11-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
 Details
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and maleic anhydride 806-508-6 1419212-77-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral Note: testing proposed with substance Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS: 1419212-76-2)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
 Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/10/2016
20/10/2016
05/12/2016
05/12/2016
 Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2016
31/05/2016
15/07/2016
15/07/2016
 Details
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol 692-731-2 76950-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
 Details
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol 695-878-0 1283129-18-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
 Details
(3-chloropropyl)triethoxysilane 225-805-6 5089-70-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
12/12/2022
12/12/2022
 Details
1,1'-(1,1,2,2-tetramethylethylene)dibenzene 217-568-2 1889-67-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
1,1'-(p-tolylimino)dipropan-2-ol 254-075-1 38668-48-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/03/2016
17/04/2015
28/04/2016
04/06/2015
 Details
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol 264-261-4 63469-23-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
 Details
1,1'-[oxybis(ethyleneoxy)]diethylene 212-133-3 764-99-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/03/2023
01/03/2023
17/04/2023
17/04/2023
 Details
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 241-881-3 17955-88-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane 220-099-6 2627-95-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
 Details
1,1,3,3-tetramethylbutyl hydroperoxide 227-369-2 5809-08-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
 Details
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
1,1`-(1,1-dimethyl-3-methylene-1,3-propanediyl)bisbenzene 228-846-8 6362-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
1,2-dimethylimidazole 217-101-2 1739-84-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
03/12/2020
03/12/2020
 Details
1,3,5-triazine-2,4,6(1H,3H,5H)-trithione, trisodium salt 241-749-5 17766-26-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
1,3,5-tris[3-(trimethoxysilyl)propyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 247-465-8 26115-70-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
 Details
1,3-diisopropylbenzene 202-773-1 99-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester 701-012-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/12/2018
10/12/2018
24/01/2019
24/01/2019
 Details
1,4-dimethylpiperazine 203-412-0 106-58-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether 291-813-1 90480-76-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
03/12/2020
03/12/2020
 Details
1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane 479-930-8 613222-52-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
1,8-diazabicyclo[5.4.0]undec-7-ene 229-713-7 6674-22-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
1-(vinyloxy)octadecane 213-208-3 930-02-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine 411-930-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
 Details
1-isopropyl-4-methylcyclohexane 202-790-4 99-82-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
1-methylimidazole 210-484-7 616-47-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether 926-564-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2019
21/10/2019
05/12/2019
05/12/2019
 Details
2,2'-(octylimino)bisethanol 239-555-0 15520-05-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/11/2019
25/11/2019
09/01/2020
09/01/2020
 Details
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] 245-509-0 23235-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2016
29/04/2016
13/06/2016
13/06/2016
 Details
2,2'-azobis[2-methylpropionamidine] dihydrochloride 221-070-0 2997-92-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
05/07/2018
05/07/2018
20/08/2018
20/08/2018
 Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
 Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
 Details
2,2-dimethyl-3-oxopropyl dodecanoate 468-880-2 102985-93-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide 686-241-8 81058-27-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
 Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- 485-230-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
 Details
2,4-Pentanedione, peroxide 253-384-9 37187-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
 Details
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
 Details
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
 Details
2-butyl-2-ethylpropanediol 204-111-7 115-84-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
31/03/2011
31/03/2011
 Details
2-ethyl-4-methylimidazole 213-234-5 931-36-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine 217-461-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
01/03/2012
01/03/2012
 Details
2-ethylhexanoic acid, monoester with propane-1,2-diol 285-503-5 85114-00-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
 Details
2-imidazolidone 204-436-4 120-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
2-Oxepanone, polymer with 1,4-butanediol 608-670-1 31831-53-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
2-phenoxyethyl acrylate 256-360-6 48145-04-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs 307-276-4 97592-79-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
 Details
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate 258-053-2 52628-03-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
 Details
2-tert-butylphenol 201-807-2 88-18-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
3,3'-iminodi(propylamine) 200-261-2 56-18-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
 Details
3,3'-oxybis(ethyleneoxy)bis(propylamine) 224-207-2 4246-51-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2021
18/02/2021
05/04/2021
05/04/2021
 Details
3,3,5-trimethylcyclohexan-1-one 212-855-9 873-94-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
 Details
3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane 262-061-1 60111-54-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
01/12/2014
01/12/2014
 Details
3,5,5-trimethylhexanoic acid 221-975-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
15/07/2011
15/07/2011
 Details
3,5,5-trimethylhexyl acetate 261-245-9 58430-94-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
3,5-dimethyl-1,2-dioxolane-3,5-diol 237-438-9 13784-51-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
16/10/2017
16/10/2017
 Details
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide 221-088-9 3001-98-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
 Details
3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate 700-071-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
02/07/2012
02/07/2012
 Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine 939-485-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
3-(dimethylamino)propylurea 401-950-2 31506-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/06/2023
06/06/2023
21/07/2023
21/07/2023
 Details
3-(trimethoxysilyl)propiononitrile 219-764-3 2526-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
 Details
3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile 300-496-1 93940-97-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
 Details
3-aminopropyldiethylamine 203-236-4 104-78-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
 Details
3-Ethenyl-5-methyl-2-oxazolidinone 809-852-5 3395-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
13/11/2017
13/11/2017
 Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
 Details
3-mercaptopropionic acid 203-537-0 107-96-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/09/2023
04/09/2023
19/10/2023
19/10/2023
 Details
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 2-methylimidazole 500-181-0 68002-42-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
 Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine 500-101-4 38294-64-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
4,4'-sulfonyldiphenol 201-250-5 80-09-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
4-(1,1-dimethylethyl)cyclohexyl acrylate 282-104-8 84100-23-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/03/2020
23/03/2020
07/05/2020
07/05/2020
 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
4-methylthiosemicarbazide 229-563-2 6610-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
 Details
4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
4-oxovaleric acid 204-649-2 123-76-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/12/2018
10/12/2018
24/01/2019
24/01/2019
 Details
4-trans-Propyl-4-trans-vinyl-[1,1-bicylohexyl] 601-409-2 116020-44-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
 Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
 Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
 Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene) 807-130-4 53716-82-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/08/2021
26/08/2021
11/10/2021
11/10/2021
 Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
 Details
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
 Details
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt 254-135-7 38820-59-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate 410-800-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
20/04/2012
20/04/2012
 Details
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2017
17/05/2017
03/07/2017
03/07/2017
 Details
Adipohydrazide 213-999-5 1071-93-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
 Details
Alcohols, C6-8, ethoxylated 800-182-9 1426148-68-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
 Details
alkyl amine and alkylbenzenesulphonate - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018
 Details
Allyl (cyclohexyloxy)acetate 272-657-3 68901-15-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/08/2018
10/08/2018
24/09/2018
24/09/2018
 Details
Amides, C16-C18 (even numbered) 931-695-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
 Details
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