Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) | 218-679-9 | 2215-35-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
butan-2-one O,O',O''-(vinylsilylidyne)trioxime | 218-747-8 | 2224-33-1 |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9). |
25/06/2015 | 10/08/2015 | Details | |
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl | 218-760-9 | 2226-96-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl | 218-760-9 | 2226-96-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 |
Details | |
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide | 218-915-0 | 2280-49-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Octyl octanoate | 218-980-5 | 2306-88-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Sub-chronic toxicity (90-day): oral - |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2017 |
Details | |
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride | 219-348-1 | 2421-28-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
2-Hexyldecan-1-ol | 219-370-1 | 2425-77-6 | Reproductive toxicity (two-generation reproductive toxicity) | 05/04/2011 | 20/05/2011 | Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): most appropriate route |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) | 23/03/2020 | 07/05/2020 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Reproductive toxicity (developmental toxicity) | 08/04/2010 | 24/05/2010 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
2-(2H-benzotriazol-2-yl)-p-cresol | 219-470-5 | 2440-22-4 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) | 219-514-3 | 2451-62-9 | Reproductive toxicity (two-generation reproductive toxicity) | 19/11/2010 | 03/01/2011 | Details | |
Strontium bis(2-ethylhexanoate) | 219-536-3 | 2457-02-5 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) | 23/11/2020 | 07/01/2021 | Details | |
3-(trimethoxysilyl)propiononitrile | 219-764-3 | 2526-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 16/02/2015 | 02/04/2015 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 01/08/2012 | 17/09/2012 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 |
6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 | Reproductive toxicity (pre-natal developmental toxicity) | 26/04/2019 | 10/06/2019 | Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
3-chloropropyltrimethoxysilane | 219-787-9 | 2530-87-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
2,2'-methylenediphenyl diisocyanate | 219-799-4 | 2536-05-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
Triethoxypropylsilane | 219-842-7 | 2550-02-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
4-phenylbutan-2-one | 219-847-4 | 2550-26-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons | 22/11/2017 | 08/01/2018 | Details | |
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 219-863-1 | 2554-06-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 17/04/2014 17/04/2014 |
Details | |
Dimethyl 2,2'-azobis(2-methylpropionate) | 219-976-6 | 2589-57-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]triethoxysilane | 220-011-6 | 2602-34-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
1,1,3,3-tetramethyl-1,3-divinyldisiloxane | 220-099-6 | 2627-95-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
N-ethyl-2-pyrrolidone (NEP) | 220-250-6 | 2687-91-4 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
Allyl 3-cyclohexylpropionate | 220-292-5 | 2705-87-5 | Reproductive toxicity (pre-natal developmental toxicity) | 26/10/2022 | 12/12/2022 | Details | |
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate | 220-482-8 | 2781-11-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form | 220-509-3 | 2786-76-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) | 03/10/2023 | 17/11/2023 | Details | |
N-(1,1-dimethyl-3-oxobutyl)acrylamide | 220-713-2 | 2873-97-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane | 220-780-8 | 2897-60-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 16/12/2016 | 30/01/2017 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 | Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) | 17/04/2015 | 04/06/2015 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
Trimethoxyphenylsilane | 221-066-9 | 2996-92-1 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
2,2'-azobis[2-methylpropionamidine] dihydrochloride | 221-070-0 | 2997-92-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide | 221-088-9 | 3001-98-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
tert-butyl 2-ethylperoxyhexanoate | 221-110-7 | 3006-82-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 30/05/2011 |
Details | |
Cyclohexylidenebis[tert-butyl] peroxide | 221-111-2 | 3006-86-8 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
bis(2-dimethylaminoethyl)(methyl)amine | 221-201-1 | 3030-47-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
hex-3-yne-2,5-diol | 221-209-5 | 3031-66-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) | 221-220-5 | 3033-62-3 |
7.8.1 Toxicity to reproduction 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
Tetra(isobutyl)thioperoxydicarbamic acid | 221-312-5 | 3064-73-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 |
Details | |
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine | 221-336-6 | 3069-29-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Trimethoxyoctylsilane | 221-338-7 | 3069-40-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
trimethoxyoctylsilane | 221-338-7 | 3069-40-7 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) | 07/08/2015 | 22/09/2015 | Details | |
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether | 221-453-2 | 3101-60-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2014 17/06/2014 17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 01/08/2014 01/08/2014 |
Details | |
2-methoxyethyl acrylate | 221-499-3 | 3121-61-7 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol | 221-573-5 | 3147-75-9 | Bioaccumulation aquatic / sediment | 15/07/2014 | 29/08/2014 | Details | |
Furan-2,5-dicarboxylic acid | 221-800-8 | 3238-40-2 | Reproductive toxicity (pre-natal developmental toxicity) | 27/05/2019 | 11/07/2019 | Details | |
1,1,3,3-tetramethyldisiloxane | 221-906-4 | 3277-26-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
Propylidynetrimethyl trimethacrylate | 221-950-4 | 3290-92-4 | Reproductive toxicity (pre-natal developmental toxicity) | 31/05/2016 | 15/07/2016 | Details | |
Propylidynetrimethyl trimethacrylate | 221-950-4 | 3290-92-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/04/2019 | 10/06/2019 | Details | |
3,5,5-trimethylhexanoic acid | 221-975-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
sodium O,O-diethyl dithiophosphate || Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5) | 222-079-2 | 3338-24-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
tert-pentyl hydroperoxide | 222-321-7 | 3425-61-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
07/10/2016 07/10/2016 |
21/11/2016 21/11/2016 |
Details | |
tert-pentyl hydroperoxide | 222-321-7 | 3425-61-4 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
Bisisobutyryl peroxide | 222-340-0 | 3437-84-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 19/05/2014 |
Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
Icos-1-ene | 222-374-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
tert-butyl α,α-dimethylbenzyl peroxide | 222-389-8 | 3457-61-2 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/03/2015 | 30/04/2015 | Details | |
tert-butyl α,α-dimethylbenzyl peroxide | 222-389-8 | 3457-61-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 27/01/2020 | 12/03/2020 | Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
1-butylpyrrolidin-2-one | 222-437-8 | 3470-98-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/01/2022 | 11/03/2022 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/02/2011 | 31/03/2011 | Details | |
N-butylbenzenesulphonamide | 222-823-6 | 3622-84-2 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
1,3-bis(isocyanatomethyl)benzene | 222-852-4 | 3634-83-1 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
Dioctyltin dilaurate | 222-883-3 | 3648-18-8 | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
Diundecyl phthalate | 222-884-9 | 3648-20-2 | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
Octa-1,7-diene | 223-054-9 | 3710-30-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
bis(3,5,5-trimethylhexanoyl) peroxide | 223-356-0 | 3851-87-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Bumetrizole | 223-445-4 | 3896-11-5 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
Sodium chloroacetate | 223-498-3 | 3926-62-3 | Reproductive toxicity (pre-natal developmental toxicity) | 14/10/2011 | 28/11/2011 | Details | |
Sodium chloroacetate | 223-498-3 | 3926-62-3 | Reproductive toxicity (two-generation reproductive toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
2,3-epoxypropyl isopropyl ether | 223-672-9 | 4016-14-2 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 |
Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide | 223-829-1 | 4090-51-1 | Sub-chronic toxicity (90-day): oral | 16/06/2022 | 01/08/2022 | Details | |
Tris(p-isocyanatophenyl) thiophosphate | 223-981-9 | 4151-51-3 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate | 223-989-2 | 4156-21-2 | Reproductive toxicity (pre-natal developmental toxicity) | 03/04/2023 | 22/05/2023 | Details | |
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate | 223-989-2 | 4156-21-2 | Sub-chronic toxicity (90-day): oral | 29/04/2014 | 13/06/2014 | Details | |
2,2-dimethylpropane-1,3-diyl dibenzoate | 224-081-9 | 4196-89-8 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate | 224-116-8 | 4203-89-8 | Genetic toxicity in vivo | 23/03/2020 | 07/05/2020 | Details | |
3,3'-oxybis(ethyleneoxy)bis(propylamine) | 224-207-2 | 4246-51-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |