Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| 3,3,4,4,5,5,6,6,6-nonafluorohexene | 243-053-7 | 19430-93-4 | Sub-chronic toxicity (90 day): inhalation | 14/08/2014 | 28/09/2014 | Details | |
| 3,3,5-trimethylcyclohexan-1-one | 212-855-9 | 873-94-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| 3,3-bis[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-1,5-divinyltrisiloxane | 262-061-1 | 60111-54-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 |
Details | |
| 3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran | 251-090-5 | 32539-83-6 | Genetic toxicity in vivo | 14/02/2011 | 31/03/2011 | Details | |
| 3,4-dihydroxy-1-[(Z)-octadec-9-enyl]pyrrolidine-2,5-dione | 700-233-4 | - |
Bioaccumulation aquatic / sediment Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
04/09/2023 04/09/2023 04/09/2023 |
19/10/2023 19/10/2023 19/10/2023 |
Details | |
| 3,4-dihydroxybenzonitrile | 241-367-9 | 17345-61-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
| 3,5,5-trimethylhexanoic acid | 221-975-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
| 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate | 261-665-2 | 59219-71-5 | Sub-chronic toxicity (90-day): oral | 24/02/2020 | 09/04/2020 | Details | |
| 3,5,5-trimethylhexyl acetate | 261-245-9 | 58430-94-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
| 3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle | - | - | Genetic toxicity in vivo | 16/03/2015 | 30/04/2015 | Details | |
| 3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt | 480-890-9 | 906532-68-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 18/11/2014 | 02/01/2015 | Details | |
| 3,5-dimethyl-1,2-dioxolane-3,5-diol | 237-438-9 | 13784-51-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
| 3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 |
Details | |
| 3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
| 3,6,9,12-tetraoxotridecanol | 245-883-5 | 23783-42-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
| 3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione | 401-540-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 11/05/2018 |
Details | |
| 3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | 416-250-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/09/2012 | 12/11/2012 | Details | |
| 3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione | 413-920-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/09/2012 | 12/11/2012 | Details | |
| 3,7-dimethyloct-6-enenitrile | 257-288-8 | 51566-62-2 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
| 3,7-dimethyloctan-1-ol | 203-374-5 | 106-21-8 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
| 3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane | 229-542-8 | 6600-31-3 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| 3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide | 221-088-9 | 3001-98-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
| 3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate | 700-071-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 |
Details | |
| 3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride | 427-370-1 | 164288-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine | 939-485-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) | 939-448-5 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-(benzothiazol-2-yl)-7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carbonitrile | 274-668-9 | 70546-25-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
| 3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile | 257-884-8 | 52372-36-8 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
| 3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid | 434-070-2 | - | Sub-chronic toxicity (90-day): oral | 18/02/2013 | 04/04/2013 | Details | |
| 3-(dimethylamino)propylurea | 401-950-2 | 31506-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 |
Details | |
| 3-(isodecyloxy)propylammonium acetate | 249-166-8 | 28701-67-9 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
| 3-(triethoxysilyl)propanethiol | 238-883-1 | 14814-09-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
| 3-(trimethoxysilyl)propiononitrile | 219-764-3 | 2526-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
| 3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate | 642-902-2 | 163802-53-7 | Genetic toxicity in vivo | 10/03/2017 | 25/04/2017 | Details | |
| 3-(trimethoxysilyl)propyl isocyanate | 239-415-9 | 15396-00-6 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5) |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
| 3-(trimethoxysilyl)propylamine | 237-511-5 | 13822-56-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
| 3-[(3-{[(3-acetoxy-2,2-dimethylpropylidene)amino]methyl}-3,5,5-trimethylcyclohexyl)imino]-2,2-dimethylpropyl acetate | 805-722-7 | 1064082-81-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 17/12/2019 | 31/01/2020 | Details | |
| 3-[(5-cyano-6-hydroxy-1,4-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]phenyl benzoate | 953-951-7 | - | 7.6.2 Genetic toxicity in vivo | 08/03/2024 | 22/04/2024 | Details | |
| 3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid | - | - | Developmental toxicity (pre-natal developmental toxicity) | 15/03/2011 | 29/04/2011 | Details | |
| 3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile | 300-496-1 | 93940-97-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
| 3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 213-485-0 | 957-68-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/08/2018 10/08/2018 10/08/2018 |
24/09/2018 24/09/2018 24/09/2018 |
Details | |
| 3-amino-4-octanol | 482-070-6 | 1001354-72-8 | Reproductive toxicity (developmental toxicity) | 19/11/2010 | 03/01/2011 | Details | |
| 3-aminopropyldiethylamine | 203-236-4 | 104-78-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
| 3-aminopropyltriethoxysilane | 213-048-4 | 919-30-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
| 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide | 931-324-9 | - | Sub-chronic toxicity (90-day): oral | 02/09/2011 | 17/10/2011 | Details | |
| 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide | 939-581-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/03/2018 | 11/05/2018 | Details | |
| 3-chloropropyltrimethoxysilane | 219-787-9 | 2530-87-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
| 3-Ethenyl-5-methyl-2-oxazolidinone | 809-852-5 | 3395-98-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
| 3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
| 3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |