Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) | 500-004-7 | 9003-29-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Butyl glycollate | 230-991-7 | 7397-62-8 | Sub-chronic toxicity (90-day): oral | 15/04/2011 | 30/05/2011 | Details | |
Butyronitrile | 203-700-6 | 109-74-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
C,C'-azodi(formamide) | 204-650-8 | 123-77-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/11/2021 | 10/01/2022 | Details | |
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons | 700-762-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
25/09/2012 25/09/2012 |
12/11/2012 12/11/2012 |
Details | |
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons | 700-762-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance. |
01/10/2018 01/10/2018 01/10/2018 |
15/11/2018 15/11/2018 15/11/2018 |
Details | |
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters | 701-257-8 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5) | 10/08/2018 | 24/09/2018 | Details | |
C16-(branched), C20-(branched) and C24-(branched)-alkanes | 700-992-1 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2018 28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 16/04/2018 |
Details | |
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite | 947-655-7 | - | Long-term toxicity to fish||Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6) | 15/01/2024 | 29/02/2024 | Details | |
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes | 700-497-0 | - |
Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/11/2010 25/06/2012 |
03/01/2011 09/08/2012 |
Details | |
C26-28 (even numbered) α-alkenes | 934-268-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2012 18/06/2012 18/06/2012 |
02/08/2012 02/08/2012 02/08/2012 |
Details | |
C8-C26 branched and linear hydrocarbons - Distillates | 481-740-5 | 848301-67-7 | Bioaccumulation aquatic / sediment | 11/05/2010 | 25/06/2010 | Details | |
Calcium 4-chloro-2-(5-hydroxy-3-methyl-1-(3-sulfonatophenyl)pyrazol-4-ylazo)-5-methylbenzenesulfonate | 403-530-4 | 129423-54-7 | 7.8.2 Developmental toxicity / teratogenicity | 08/03/2024 | 22/04/2024 | Details | |
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) | 939-717-7 | - | Sub-chronic toxicity (90-day): oral | 02/06/2014 | 17/07/2014 | Details | |
Calcium carbonate | 207-439-9 | 471-34-1 | Sub-chronic toxicity (90 day): inhalation | 15/07/2011 | 29/08/2011 | Details | |
calcium cyanamide | 205-861-8 | 156-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
Calcium cyanamide | 205-861-8 | 156-62-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification | 932-124-4 | - | Sub-chronic toxicity (90 day): inhalation | 01/07/2011 | 15/08/2011 | Details | |
Camphene | 201-234-8 | 79-92-5 | Sub-chronic toxicity (90-day): oral | 24/02/2020 | 09/04/2020 | Details | |
Carboxylic acids, di-, C4-6 | 271-678-5 | 68603-87-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with adipic acid (EC 204-673-3) | 21/10/2021 | 07/12/2021 | Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated | 941-216-3 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue | 941-212-1 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled | - | - |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Cashew, nutshell liq. | 232-355-4 | 8007-24-7 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 31/10/2011 |
Details | |
Cashew, nutshell liq., oligomeric reaction products with 1-chloro-2,3-epoxypropane | - | 68413-24-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
cerium trinitrate | 233-297-2 | 10108-73-3 | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Cesium fluoroaluminate | 604-086-6 | 138577-01-2 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
Chloroacetic acid | 201-178-4 | 79-11-8 | Reproductive toxicity (two-generation reproductive toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Chloroacetic acid | 201-178-4 | 79-11-8 | Reproductive toxicity (pre-natal developmental toxicity) | 14/10/2011 | 28/11/2011 | Details | |
chlorodimethylvinylsilane | 217-007-1 | 1719-58-0 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) | 12/12/2014 | 26/01/2015 | Details | |
Chloroethane | 200-830-5 | 75-00-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 |
Details | |
Choline hydroxide | 204-625-1 | 123-41-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) | 25/05/2020 | 09/07/2020 | Details | |
Citral | 226-394-6 | 5392-40-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Citronellyl formate | 203-338-9 | 105-85-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
Cobalt | 231-158-0 | 7440-48-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt | 231-158-0 | 7440-48-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt (II) dinitrate | 233-402-1 | 10141-05-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt (II) sulphate | 233-334-2 | 10124-43-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) ; after obtaining results of the 90-day subchronic toxicity study Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt bis(2-ethylhexanoate) | 205-250-6 | 136-52-7 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt bis(2-ethylhexanoate) | 205-250-6 | 136-52-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
cobalt carbonate | 208-169-4 | 513-79-1 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
cobalt di(acetate) | 200-755-8 | 71-48-7 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt dichloride | 231-589-4 | 7646-79-9 |
Carcinogenicity
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt dichloride | 231-589-4 | 7646-79-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt dihydroxide | 244-166-4 | 21041-93-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt dihydroxide | 244-166-4 | 21041-93-0 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
cobalt dinitrate | 233-402-1 | 10141-05-6 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Cobalt hydroxide oxide | 234-614-7 | 12016-80-7 |
Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Cobalt sulphide (EC 215-273-3)
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90 day): inhalation
|| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2)
|| Note: Testing proposal is based on concern identified by the registrant |
21/09/2020 21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 05/11/2020 |
Details | |
Cobalt hydroxide oxide | 234-614-7 | 12016-80-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt lithium dioxide | 235-362-0 | 12190-79-3 |
Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90 day): inhalation
|| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt oxide | 215-154-6 | 1307-96-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt oxide | 215-154-6 | 1307-96-6 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
cobalt sulphate | 233-334-2 | 10124-43-3 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Cobalt sulphide | 215-273-3 | 1317-42-6 |
Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): inhalation
|| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2)
|| Note: Testing proposal is based on concern identified by the registrant |
21/09/2020 21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 05/11/2020 |
Details | |
Cobalt sulphide | 215-273-3 | 1317-42-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(2+) propionate | 216-333-1 | 1560-69-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) 4-oxopent-2-en-2-olate | 237-855-6 | 14024-48-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) 4-oxopent-2-en-2-olate | 237-855-6 | 14024-48-7 |
"Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant.
" Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt(II) carbonate | 208-169-4 | 513-79-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) diacetate | 200-755-8 | 71-48-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt, borate 2-ethylhexanoate complexes | 295-032-7 | 91782-60-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
Cobalt, borate neodecanoate complexes | 270-601-2 | 68457-13-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt, borate neodecanoate complexes | 270-601-2 | 68457-13-6 | Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) | 21/01/2021 | 08/03/2021 | Details | |
Cobalt, borate propionate complexes | 295-033-2 | 91782-61-5 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane | 640-964-5 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 |
Genetic toxicity in vivo
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuels, diesel (EC 269-822-7)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2)
- Fuels, diesel (EC 269-822-7) Sub-chronic toxicity (90 day): dermal
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid | 641-088-6 | - |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 30/09/2011 |
Details | |
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine | 605-296-0 | 162627-17-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
Condensation products of phenol and salicylaldehyde | 947-320-5 | - | Genetic toxicity in vivo | 20/05/2021 | 05/07/2021 | Details | |
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride | - | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/03/2017 10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 25/04/2017 |
Details | |
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate | 600-028-9 | 1001254-87-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): dermal |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Copolymer of benzenamine and formaldehyde, hydrogenated | 603-894-6 | 135108-88-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2) | 800-038-5 | 1071838-81-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/01/2015 | 09/03/2015 | Details | |
Copper hydroxide nitrate | 439-590-3 | 12158-75-7 | Reproductive toxicity (pre-natal developmental toxicity) | 03/11/2011 | 19/12/2011 | Details | |
Copper(I, II) sulfite | 884-197-6 | 15293-86-4 | 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) | 08/03/2024 | 22/04/2024 | Details | |
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts | - | - | 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 | 03/12/2010 | 17/01/2011 | Details | |
Cyclohex-1,2-ylenediamine | 211-776-7 | 694-83-7 | Genetic toxicity in vivo | 22/09/2022 | 07/11/2022 | Details | |
Cyclohexane-1,4-dicarboxylic acid | 214-068-6 | 1076-97-7 | Reproductive toxicity (pre-natal developmental toxicity) | 27/11/2013 | 10/01/2014 | Details | |
Cyclohexane-1,4-diyldimethanol | 203-268-9 | 105-08-8 | OECD Guideline 414 (Prenatal Developmental Toxicity Study) | 19/11/2010 | 03/01/2011 | Details | |
Cyclohexanone, peroxide | 235-527-7 | 12262-58-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Cyclohexyldimethoxymethylsilane | 402-140-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
Cyclohexyldimethylamine | 202-715-5 | 98-94-2 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
Cyclohexylidenebis[tert-butyl] peroxide | 221-111-2 | 3006-86-8 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts | 609-542-8 | 383178-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol | 446-990-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/01/2015 23/01/2015 |
09/03/2015 09/03/2015 |
Details | |
d-Glucose, ether with glycerol | 309-496-6 | 100402-60-6 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
Dec-1-ene | 212-819-2 | 872-05-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
decahydronaphthalene | 202-046-9 | 91-17-8 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
Decahydronaphthalene | 202-046-9 | 91-17-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Decamethylcyclopentasiloxane | 208-764-9 | 541-02-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
Decamethylenediamine | 211-471-9 | 646-25-3 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
decamethyltetrasiloxane | 205-491-7 | 141-62-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/10/2014 | 01/12/2014 | Details | |
Decanal | 203-957-4 | 112-31-2 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
Decane | 204-686-4 | 124-18-5 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Decene | 246-870-7 | 25339-53-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Decene, hydroformylation products, high boiling | 935-454-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Destillation fraction of chlorosilanes | 700-717-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 |
Details | |
di(morpholin-4-yl) disulphide | 203-103-0 | 103-34-4 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
Di(tetraethylammonium)hexahydroxoplatinate(IV) | 848-537-7 | 1912392-88-1 | Genetic toxicity in vivo | 21/09/2020 | 05/11/2020 | Details | |
Di-''isononyl'' phthalate | 249-079-5 | 28553-12-0 | Reproductive toxicity (pre-natal developmental toxicity) | 22/09/2022 | 07/11/2022 | Details | |
di-p-tolyl(2,4,6-trimethylbenzoyl)phosphine oxide | 884-585-5 | 270586-78-2 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/06/2023 30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 14/08/2023 |
Details | |
di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide | 201-128-1 | 78-63-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/10/2011 14/10/2011 |
28/11/2011 28/11/2011 |
Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Bioaccumulation aquatic / sediment | 01/04/2022 | 16/05/2022 | Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Bioaccumulation aquatic / sediment | 25/06/2019 | 09/08/2019 | Details | |
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide | 229-782-3 | 6731-36-8 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2011 | 15/08/2011 | Details | |
Di-tert-butyl peroxide | 203-733-6 | 110-05-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/03/2023 01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 17/04/2023 |
Details | |
Dialkyl-methyl-dihydro-heteropolycyle | 815-131-6 | 913171-06-9 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/03/2020 | 07/05/2020 | Details | |
Diamminediisocyanatozinc | 401-610-3 | 122012-52-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Diammonium dihydrogen ethylenediaminetetraacetate | 244-063-4 | 20824-56-0 | Sub-chronic toxicity (90 day): inhalation | 29/07/2011 | 12/09/2011 | Details | |
Diammonium hexachloroplatinate | 240-973-0 | 16919-58-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/04/2018 | 07/06/2018 | Details | |
diammonium hexanitratocerate | 240-827-6 | 16774-21-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4) | 20/05/2015 | 06/07/2015 | Details | |
Dibenzoyl peroxide | 202-327-6 | 94-36-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
Dibenzoyl peroxide | 202-327-6 | 94-36-0 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Dibismuth trioxide | 215-134-7 | 1304-76-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
Dibutyl fumarate | 203-327-9 | 105-75-9 | Long-term toxicity to fish | 16/05/2011 | 30/06/2011 | Details | |
Dibutyl hydrogen phosphate | 203-509-8 | 107-66-4 | Long-term toxicity to fish | 10/05/2022 | 27/06/2022 | Details | |
Dibutyl itaconate | 218-451-9 | 2155-60-4 |
Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
dichloro(3-chloropropyl)methylsilane | 232-136-3 | 7787-93-1 | Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3) | 16/10/2014 | 01/12/2014 | Details | |
dichloro(diphenyl)silane | 201-251-0 | 80-10-4 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9) Sub-chronic toxicity (90-day): oral Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9) |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Dichloro(methyl)(phenyl)silane | 205-746-2 | 149-74-6 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) | 04/04/2014 | 19/05/2014 | Details | |
Dichlorobis(η-cyclopentadienyl)titanium | 215-035-9 | 1271-19-8 | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
dichlorocyclohexylmethylsilane | 226-956-0 | 5578-42-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) | 16/03/2015 | 30/04/2015 | Details | |
Dichloromethylbenzene | 249-854-8 | 29797-40-8 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
Dichloromethylbenzene | 249-854-8 | 29797-40-8 | Reproductive toxicity (pre-natal developmental toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Dicyclohexylamine | 202-980-7 | 101-83-7 |
Genetic toxicity in vivo (mammalian bone marrow chromosome aberration test) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/03/2011 15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 29/04/2011 |
Details | |
Dicyclopentyldimethoxysilane | 404-370-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2011 16/12/2011 16/12/2011 |
30/01/2012 30/01/2012 30/01/2012 |
Details | |
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate | 220-482-8 | 2781-11-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
Diethyl carbonate | 203-311-1 | 105-58-8 | Genetic toxicity in vivo | 18/02/2014 | 04/04/2014 | Details | |
Diethyl ether | 200-467-2 | 60-29-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
diethyl ether | 200-467-2 | 60-29-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
Diethyl ethylphosphonate | 201-111-9 | 78-38-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Diethylamine | 203-716-3 | 109-89-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dimethylamine (CAS 124-40-3) | 21/09/2020 | 05/11/2020 | Details | |
Diethylmethylbenzenediamine | 270-877-4 | 68479-98-1 | Long-term toxicity to fish | 04/12/2023 | 18/01/2024 | Details | |
Diethylmethylbenzenediamine | 270-877-4 | 68479-98-1 | Reproductive toxicity (pre-natal developmental toxicity) | 29/07/2011 | 12/09/2011 | Details | |
Dihexadecyl peroxodicarbonate | 247-611-0 | 26322-14-5 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4) Sub-chronic toxicity (90-day): oral |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
dihydro-3-(tripropenyl)furan-2,5-dione | 295-556-6 | 92077-08-2 | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2015 | 16/11/2015 | Details | |
Dihydrogen hexahydroxyplatinate | 257-471-2 | 51850-20-5 | Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. | 28/02/2018 | 16/04/2018 | Details | |
Dihydrogen hexahydroxyplatinate | 257-471-2 | 51850-20-5 | Genetic toxicity in vivo || Note: testing proposed with dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) (EC 268-717-3) | 21/12/2021 | 04/02/2022 | Details | |
Dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) | 268-717-3 | 68133-90-4 | Genetic toxicity in vivo | 21/12/2021 | 04/02/2022 | Details | |
Dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) | 268-717-3 | 68133-90-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 04/10/2018 | 19/11/2018 | Details | |
Diisodecyl sebacate | 249-047-0 | 28473-19-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Diisononyl adipate | 251-646-7 | 33703-08-1 |
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) |
03/05/2023 03/05/2023 |
19/06/2023 19/06/2023 |
Details | |
Diisopentyl ether | 208-857-4 | 544-01-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
Diisopropyl ether | 203-560-6 | 108-20-3 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
Diisopropylbenzene hydroperoxide | 247-988-1 | 26762-93-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Dilauroyl peroxide | 203-326-3 | 105-74-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
dimethoxydimethylsilane | 214-189-4 | 1112-39-6 | Sub-chronic toxicity (90 day): inhalation | 16/10/2014 | 01/12/2014 | Details | |
dimethoxydimethylsilane | 214-189-4 | 1112-39-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
dimethoxydiphenylsilane | 229-929-1 | 6843-66-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Dimethoxymethane | 203-714-2 | 109-87-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
dimethoxymethylsilane | 240-914-9 | 16881-77-9 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(methyl)silane. | 16/10/2014 | 01/12/2014 | Details | |
Dimethoxymethylsilane | 240-914-9 | 16881-77-9 | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
Dimethyl (p-methoxybenzylidene)malonate | 231-185-8 | 7443-25-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 23/03/2020 | 07/05/2020 | Details | |
Dimethyl 2,2'-azobis(2-methylpropionate) | 219-976-6 | 2589-57-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Dimethyl cyclohexane-1,4-dicarboxylate | 202-347-5 | 94-60-0 | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
Dimethyl sebacate | 203-431-4 | 106-79-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 17/03/2014 |
Details | |
Dimethyl sulfoxide | 200-664-3 | 67-68-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
Dimethyl(propyl)amine | 213-139-9 | 926-63-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
Dimethylamine | 204-697-4 | 124-40-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Dimethylpropane-1,3-diol | 204-781-0 | 126-30-7 |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day) |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
Dioctadecyl 3,3'-thiodipropionate | 211-750-5 | 693-36-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
Dioctyltin dilaurate | 222-883-3 | 3648-18-8 | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
Dioxydibutane-2,2-diyl dihydroperoxide | 215-661-2 | 1338-23-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
Diphenyl sulphone | 204-853-1 | 127-63-9 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2014 | 04/04/2014 | Details | |
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide | 278-355-8 | 75980-60-8 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2014 | 04/04/2014 | Details | |
Diphosphoric acid, compd. with piperazine (1:1) | 457-330-7 | 66034-17-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine | 239-590-1 | 15541-60-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer | 234-293-3 | 11071-15-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
dipotassium heptafluorotantalate | 240-986-1 | 16924-00-8 | Genetic toxicity in vivo | 16/03/2015 | 30/04/2015 | Details | |
Dipotassium hexachloroplatinate | 240-979-3 | 16921-30-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 26/03/2018 | 11/05/2018 | Details | |
Dipotassium tetrachloroplatinate | 233-050-9 | 10025-99-7 | Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." | 18/06/2018 | 02/08/2018 | Details | |
Dirhodium trisulphate | 234-014-5 | 10489-46-0 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Disilver oxide | 243-957-1 | 20667-12-3 | Sub-chronic toxicity (90-day): oral | 15/04/2011 | 30/05/2011 | Details | |
Disodium 1-amino-4-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate | 274-397-6 | 70209-99-3 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Disodium 4-[4-[[5-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-2,5-dichlorobenzenesulphonate | 274-499-0 | 70247-70-0 | Genetic toxicity in vivo | 18/02/2021 | 05/04/2021 | Details | |
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate | 229-208-1 | 6428-31-5 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
Disodium 5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxy-6-(methylamino)naphthalene-2-sulphonate | 274-436-7 | 70210-39-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-[(4-methyl-3-sulphonatophenyl)sulphonyl]phenyl]azo]naphthalene-2-sulphonate | 286-122-7 | 85187-33-3 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 18/02/2021 | 05/04/2021 | Details | |
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxynaphthalene-2-sulphonate | 274-437-2 | 70210-40-1 | Genetic toxicity in vivo | 18/02/2021 | 05/04/2021 | Details | |
Disodium dihydrogen 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate | 205-358-3 | 139-33-3 | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
Disodium hydroxy-substituted alkanoate | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Disodium oxybis[methylbenzenesulphonate] | 277-242-0 | 73037-34-0 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2014 | 01/08/2014 | Details | |
Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction | 270-728-3 | 68477-39-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Sub-chronic toxicity (90-day): oral
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
Distillates (petroleum), full-range straight-run middle | 272-341-5 | 68814-87-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) (CAS 68915-96-8) | 21/01/2021 | 08/03/2021 | Details | |
Distillates (petroleum), full-range straight-run middle | 272-341-5 | 68814-87-9 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), heavy straight-run | 272-817-2 | 68915-96-8 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 | Genetic toxicity in vivo | 14/05/2020 | 29/06/2020 | Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 | Genetic toxicity in vivo | 14/05/2020 | 29/06/2020 | Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), light hydrocracked | 265-078-2 | 64741-77-1 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |