Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate) | 298-577-9 | 93819-94-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
Silver | 231-131-3 | 7440-22-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) | 27/09/2017 | 13/11/2017 | Details | |
Sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
Sodium toluene-4-sulphonate | 211-522-5 | 657-84-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate | 24/04/2015 | 12/06/2015 | Details | |
potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) | 16/12/2016 | 30/01/2017 | Details | |
sodium toluene-4-sulphonate | 211-522-5 | 657-84-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) | 16/12/2016 | 30/01/2017 | Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7) Reproductive toxicity (pre-natal developmental toxicity ) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Triethoxy(vinyl)silane | 201-081-7 | 78-08-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8) |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics | 917-828-1 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a group: Icosane (EC 204-018-1) and Hydrocarbons, C14-C19, isoalkanes, cyclics, < 2% aromatics (920-114-2) | 02/11/2018 | 17/12/2018 | Details | |
2,2,4,4,6,8,8-heptamethylnonane | 224-506-8 | 4390-04-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2) | 02/11/2018 | 17/12/2018 | Details | |
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate | 907-870-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) ||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Zinc, O,O-mixed (iso-Bu), (iso-Pr), (pentyl) phosphorodithioate | 820-225-5 | 101747-77-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) |
26/04/2019 26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 10/06/2019 |
Details | |
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate | 940-272-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 16/10/2017 |
Details | |
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate | 425-220-8 | 5945-33-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol | 701-122-3 | 106185-75-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] | 306-832-3 | 97416-84-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 |
Details | |
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol | 264-261-4 | 63469-23-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl )-3-pentanone | 436-710-6 | 756-13-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 |
Details | |
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride | 246-644-8 | 25134-21-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/11/2023 03/11/2023 |
18/12/2023 18/12/2023 |
Details | |
1,2-dimethylimidazole | 217-101-2 | 1739-84-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters | 946-149-3 | 1571954-81-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 |
Details | |
2,2-dimethyl-1,3-dioxolan-4-ylmethanol | 202-888-7 | 100-79-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2-methylpentane-2,4-diol | 203-489-0 | 107-41-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 |
Details | |
3-(trimethoxysilyl)propylamine | 237-511-5 | 13822-56-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
3-aminopropyltriethoxysilane | 213-048-4 | 919-30-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
3-chloropropyltrimethoxysilane | 219-787-9 | 2530-87-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane | 260-350-7 | 56706-10-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
4-hydroxy-4-methylpentan-2-one | 204-626-7 | 123-42-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2016 01/09/2016 |
17/10/2016 17/10/2016 |
Details | |
4-morpholinecarbaldehyde | 224-518-3 | 4394-85-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
8,9,10-trinorborn-2-ene | 207-866-0 | 498-66-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/11/2015 01/11/2015 |
16/12/2015 16/12/2015 |
Details | |
Amides, C16-C18 (even) , N,N'-ethylenebis | 931-299-4 | 68390-94-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
Amines, polyethylenepoly-, triethylenetetramine fraction | 292-588-2 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
|
Details |
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched | 292-588-2 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
ASPHALT | 232-490-9 | 8052-42-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/05/2016 31/05/2016 |
15/07/2016 15/07/2016 |
Details | |
barium titanium trioxide | 234-975-0 | 12047-27-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 |
Details | |
Benzene, diethenyl- and Benzene, ethenylethyl- | 910-757-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/08/2019 16/08/2019 |
30/09/2019 30/09/2019 |
Details | |
Biphenyl-4,4'-diol | 202-200-5 | 92-88-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
Chloroethane | 200-830-5 | 75-00-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 |
Details | |
cobalt dichloride | 231-589-4 | 7646-79-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/07/2016 18/07/2016 |
01/09/2016 01/09/2016 |
|
Details |
Ditolyl ether | 248-948-6 | 28299-41-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/10/2021 21/10/2021 |
07/12/2021 07/12/2021 |
Details | |
Docosan-1-ol | 211-546-6 | 661-19-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 |
Details | |
dodecamethylpentasiloxane | 205-492-2 | 141-63-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
Ethylene | 200-815-3 | 74-85-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
Hexamethylcyclotrisiloxane | 208-765-4 | 541-05-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
Hexan-6-olide | 207-938-1 | 502-44-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate | 252-029-5 | 34443-12-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
pentaerythritol | 204-104-9 | 115-77-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 |
Details | |
Peracetic acid | 201-186-8 | 79-21-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
Phthalic anhydride | 201-607-5 | 85-44-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
Polysulfides, bis[3-(triethoxysilyl)propyl] | 915-673-4 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 |
Details | |
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol | 911-819-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/08/2019 16/08/2019 |
30/09/2019 30/09/2019 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid | 931-291-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
Sodium metavanadate | 237-272-7 | 13718-26-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/01/2022 25/01/2022 |
11/03/2022 11/03/2022 |
Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
tetrahydro-2-methylfuran | 202-507-4 | 96-47-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Tris(2-butoxyethyl) phosphate | 201-122-9 | 78-51-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 |
Details | |
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate | 250-418-4 | 30989-05-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
undec-10-enoic acid | 203-965-8 | 112-38-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
20/05/2021 20/05/2021 |
05/07/2021 05/07/2021 |
Details | |
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts | 270-608-0 | 68457-79-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance, with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Benzene, 1,1'-oxybis-, tetrapropylene derivatives, sulfonated, sodium salts | 601-601-6 | 119345-04-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) with the Rabbit |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
2-hydroxy-2-methylpropiophenone | 231-272-0 | 7473-98-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day) |
21/10/2019 15/03/2011 15/03/2011 15/03/2011 |
05/12/2019 29/04/2011 29/04/2011 29/04/2011 |
Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Extracts (petroleum), residual oil solvent | 265-110-5 | 64742-10-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Gas oils (petroleum), hydrodesulfurized | 265-182-8 | 64742-79-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol | 701-041-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
2-methylpropene | 204-066-3 | 115-11-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Hydrocarbons, C4, 1,3-butadiene- and isobutene-free | 306-004-1 | 95465-89-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-107-7 | 40039-93-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
3,6-bis(4-chlorophenyl)-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione | 401-540-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 11/05/2018 |
Details | |
4,4'-Isopropylidenediphenol, ethoxylated | 500-082-2 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/05/2018 21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 05/07/2018 |
Details | |
Benzyldimethylamine | 203-149-1 | 103-83-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/03/2020 23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 07/05/2020 |
Details | |
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) | 500-004-7 | 9003-29-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
C16-(branched), C20-(branched) and C24-(branched)-alkanes | 700-992-1 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2018 28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 16/04/2018 |
Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/03/2023 01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 17/04/2023 |
Details | |
Dibenzoyl peroxide | 202-327-6 | 94-36-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
Ethane- 1,2-diol, propoxylated | 500-078-0 | 31923-84-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
Fatty acids, C12-14 (even numbered), methyl ester | 629-776-4 | 308065-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 15/11/2021 |
Details | |
Hexadecane | 208-878-9 | 544-76-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C10-C13, aromatics, | 922-153-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 919-164-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics | 920-114-2 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) | 919-006-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C7-C9, isoalkanes | 921-728-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C9-C10, aromatics, >1% naphthalene | 946-365-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C9-C11, isoalkanes, cyclics | 920-134-1 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/04/2019 26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 10/06/2019 |
Details | |
Lithium bis(fluorosulfonyl)imide | 686-526-7 | 171611-11-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/10/2021 21/10/2021 21/10/2021 |
07/12/2021 07/12/2021 07/12/2021 |
Details | |
Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts | 270-608-0 | 68457-79-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2016 01/09/2016 01/09/2016 |
17/10/2016 17/10/2016 17/10/2016 |
Details | |
Pivalic acid | 200-922-5 | 75-98-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/12/2017 20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 05/02/2018 |
Details | |
Pleuromulin | 204-747-5 | 125-65-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2018 06/09/2018 06/09/2018 |
22/10/2018 22/10/2018 22/10/2018 |
Details | |
Polysulfides, di-tert-dodecyl | 270-335-7 | 68425-15-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2018 31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 19/03/2018 |
Details | |
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane | 608-489-8 | 30499-70-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 10/08/2015 |
Details | |
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) | 943-172-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/05/2016 17/05/2016 17/05/2016 |
01/07/2016 01/07/2016 01/07/2016 |
Details | |
Reaction products of monoethanolamine and boric acid (1:3) | 701-024-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) | 230-257-6 | 6990-43-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- | 907-495-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit Sub-chronic toxicity (90 day): inhalation |
27/05/2019 27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 11/07/2019 |
Details | |
Propene | 204-062-1 | 115-07-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with ethylene (EC no. 200-815-3) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
N-methylaniline | 202-870-9 | 100-61-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): dermal |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
1,3-dimethylimidazolidin-2-one | 201-304-8 | 80-73-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- | 500-012-0 | 9004-77-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1). Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
Reaction products of monoethanolamine and boric acid (1:1) | 701-025-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
COBALT DICHLORIDE | 231-589-4 | 7646-79-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
4,4'-Methylenediphenyl diisocyanate, oligomers | 500-040-3 | 25686-28-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol | 701-393-8 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate | 905-806-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol | 701-072-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
1,1,1,3,3,3-hexamethyldisilazane | 213-668-5 | 999-97-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) |
16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 |
Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) | 23/03/2020 | 07/05/2020 | Details | |
Divanadium pentaoxide | 215-239-8 | 1314-62-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with sodium metavanadate (EC no. 237-272-7) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Vanadium dioxide | 234-841-1 | 12036-21-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: : testing proposed with Sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7) |
16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 |
Details | |
Sodium N-lauroylsarcosinate | 205-281-5 | 137-16-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Note: testing proposed with N-methyl-N-[C18-(unsaturated)alkanoyl]glycine (EC no. 701-177-3) | 30/06/2023 | 14/08/2023 | Details | |
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine | 229-761-9 | 6711-48-4 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4) | 22/09/2022 | 07/11/2022 | Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
2-butene | 203-452-9 | 107-01-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
But-1-ene | 203-449-2 | 106-98-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Butene | 246-689-3 | 25167-67-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 2,4'-diisocyanatodiphenylmethane | 500-297-1 | 109331-54-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 31/01/2023 | 17/03/2023 | Details | |
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form | 220-509-3 | 2786-76-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) | 03/10/2023 | 17/11/2023 | Details | |
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction | 293-263-8 | 91053-01-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Dodecene, branched | 306-479-5 | 97280-83-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5) | 06/06/2023 | 21/07/2023 | Details | |
Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics | 941-803-4 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
||Note: testing proposed with Fuels, diesel (EC no. 269-822-7)
||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5)
||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
Hydrocarbons, C4, steam-cracker distillate | 295-405-4 | 92045-23-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Xylene | 215-535-7 | 1330-20-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC No 905-588-0) | 01/03/2023 | 17/04/2023 | Details | |
Xylene | 215-535-7 | 1330-20-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC no. 905-588-0) | 31/01/2023 | 17/03/2023 | Details | |
Divanadium tris(sulphate) | 237-226-6 | 13701-70-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7) |
30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 |
Details | |
[[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt | 274-798-6 | 70714-66-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) | 01/03/2023 | 17/04/2023 | Details | |
2-methylpropane-2-thiol | 200-890-2 | 75-66-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1 ) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (pre-natal developmental toxicity | 20/10/2016 | 05/12/2016 | Details | |
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid | 225-306-3 | - |
Reproductive toxicity (pre-natal developmental toxicity study) Sub-chronic oral toxicity (90-day): oral |
05/04/2011 05/04/2011 |
20/05/2011 20/05/2011 |
Details | |
Resin acids and Rosin acids, calcium salts | 232-694-8 | 9007-13-0 |
Reproductive toxicity (pre-natal developmental toxicity || Note: Testing proposed with Rosin CAS 8050-09-7 Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin CAS 8050-09-7 Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin CAS 8050-09-7, Rosin hydrogenated CAS 65997-06-0, and Rosin reaction products with formaldehyde CAS 91081-53-7 |
02/07/2013 02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 16/08/2013 |
Details | |
Bis(trimethoxysilylpropyl)amine | 280-084-5 | 82985-35-1 |
Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
Ditetradecyl peroxydicarbonate | 258-436-4 | 53220-22-7 |
Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, monosodium sal | 616-248-3 | 75627-31-5 |
Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
23/12/2015 23/12/2015 |
03/02/2016 03/02/2016 |
Details | |
(-)-pin-2(3)-ene | 232-077-3 | 7785-26-4 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate | 266-380-7 | 66492-51-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
(E)-N-(pentan-2-ylidene)hydroxylamine | 484-470-6 | 623-40-5 | Reproductive toxicity (pre-natal developmental toxicity) | 18/03/2021 | 03/05/2021 | Details | |
(ethoxymethoxy)cyclododecane | 261-332-1 | 58567-11-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
(phenylethyl)benzene | 254-179-7 | 38888-98-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated | 926-000-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid | 701-116-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
(Z)-N-octadec-9-enylhexadecan-1-amide | 240-367-6 | 16260-09-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1,1'-(methylenedi-p-phenylene)bismaleimide | 237-163-4 | 13676-54-5 | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
1,1'-dithiobis[hexahydro-2H-azepin-2-one] | 245-910-0 | 23847-08-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol | 204-137-9 | 116-37-0 | Reproductive toxicity (pre-natal developmental toxicity) | 31/07/2015 | 14/09/2015 | Details | |
1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate | 244-894-2 | 22288-43-3 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one | 251-649-3 | 33704-61-9 | Reproductive toxicity (pre-natal developmental toxicity) | 30/06/2023 | 14/08/2023 | Details | |
1,2,4-trimethylbenzene | 202-436-9 | 95-63-6 | Reproductive toxicity (pre-natal developmental toxicity) | 03/10/2023 | 17/11/2023 | Details | |
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters | 701-339-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/05/2020 | 09/07/2020 | Details | |
1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 213-834-7 | 1025-15-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/09/2012 | 12/11/2012 | Details | |
1,3- and 1,4-cyclohexandicarboxyaldehyde | 482-020-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone | 255-460-7 | 41611-76-1 | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol | 412-300-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
1-aminopropan-2-ol | 201-162-7 | 78-96-6 | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
1-chloro-2,3-dimethylbenzene | 480-880-4 | 608-23-1 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
1-Dodecene, dimers | 814-509-8 | 62132-67-6 | Reproductive toxicity (pre-natal developmental toxicity) | 02/11/2018 | 17/12/2018 | Details | |
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate | 229-934-9 | 6846-50-0 | Reproductive toxicity (pre-natal developmental toxicity) | 14/03/2016 | 28/04/2016 | Details | |
1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. | 600-033-6 | 1001416-18-7 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
2,2'-(cyclohexylimino)bisethanol | 224-809-5 | 4500-29-2 | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
2,2'-dimethyl-2,2'-azodipropiononitrile | 201-132-3 | 78-67-1 | Reproductive toxicity (pre-natal developmental toxicity) | 03/02/2016 | 21/03/2016 | Details | |
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) | 202-319-2 | 94-28-0 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
2,2,2`,2`-Tetrakis(hydroxymethyl)-3,3`-oxydipropan-1-ol | 204-794-1 | 126-58-9 | Reproductive toxicity (pre-natal developmental toxicity) | 15/03/2011 | 29/04/2011 | Details | |
2,2,4-trimethylpentane-1,3-diol | 205-619-1 | 144-19-4 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2014 | 04/04/2014 | Details | |
2,2-Bis(hydroxymethyl)-1,3-propanediol (pentaerythritol) | 204-104-9 | 115-77-5 | Reproductive toxicity (pre-natal developmental toxicity) | 15/03/2011 | 29/04/2011 | Details | |
2,2-dimethylpropan-1-ol, tribromo derivative | 253-057-0 | 36483-57-5 | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
2,2-dimethylpropane-1,3-diyl dibenzoate | 224-081-9 | 4196-89-8 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
2,4,6-tri-tert-butylphenol | 211-989-5 | 732-26-3 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol | 411-220-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/09/2012 | 12/11/2012 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/07/2011 | 12/09/2011 | Details | |
2,6-di-tert-butylphenol | 204-884-0 | 128-39-2 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2020 | 03/08/2020 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
2-(2-(2-butoxyethoxy)ethoxy)ethanol | 205-592-6 | 143-22-6 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
2-(2-methoxyethoxy)ethanol | 203-906-6 | 111-77-3 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2019 | 05/12/2019 | Details | |
2-(dimethylamino)-2-methylpropan-1-ol | 230-279-6 | 7005-47-2 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol | 608-744-3 | 32472-85-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/03/2015 | 30/04/2015 | Details | |
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | 404-360-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
2-isocyanatoethyl methacrylate | 250-284-7 | 30674-80-7 | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
2-mercaptoethanol | 200-464-6 | 60-24-2 | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2011 | 30/05/2011 | Details | |
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol | 500-099-5 | 37625-56-2 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2011 | 29/08/2011 | Details | |