Predchádzajúce/výsledok
Predchádzajúce/výsledok
Predchádzajúce/výsledok
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
triethoxy(3-isocyanatopropyl)silane | 246-467-6 | 24801-88-5 | Genetic toxicity in vivo Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9) | 03/02/2016 | 21/03/2016 | Details | |
Triethoxy(3-isocyanatopropyl)silane | 246-467-6 | 24801-88-5 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 | Long-term toxicity to fish | 16/06/2022 | 01/08/2022 | Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 | Sub-chronic toxicity (90 day): inhalation | 14/11/2013 | 30/12/2013 | Details | |
1,2,3,6-tetrahydromethyl-3,6-methanophthalic anhydride | 246-644-8 | 25134-21-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/11/2023 03/11/2023 |
18/12/2023 18/12/2023 |
Details | |
Trixylyl phosphate | 246-677-8 | 25155-23-1 | Bioaccumulation aquatic / sediment | 02/09/2011 | 17/10/2011 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 20/04/2012 |
Details | |
Butene | 246-689-3 | 25167-67-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
2,4,4-trimethylpentene | 246-690-9 | 25167-70-8 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint. Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 |
Details | |
2,4,4-trimethylpentene | 246-690-9 | 25167-70-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 15/07/2022 | 29/08/2022 | Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Ethylenediamine, propoxylated | 500-035-6 | 25214-63-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 |
Details | |
3-(trimethoxysilyl)propiononitrile | 219-764-3 | 2526-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
Hexene | 246-768-2 | 25264-93-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Hex-1-ene (EC 209-753-1)
|| Note: testing proposed with Octadec-1-ene (EC 112-88-9)
|| Note: testing proposed with Hexadecene (EC 248-131-4)
|| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0)
|| Note: testing proposed with Nonene, branched (EC 306-492-6) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hex-1-ene (EC 209-753-1)
|| Note: testing proposed with Octadec-1-ene (EC 112-88-9)
|| Note: testing proposed with Octadecene (EC 248-205-6)
|| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0)
|| Note: testing proposed with Nonene, branched (EC 306-492-6) |
23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 |
Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/04/2019 26/04/2019 26/04/2019 |
10/06/2019 10/06/2019 10/06/2019 |
Details | |
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
Tetrapropylenebenzene | 246-772-4 | 25265-78-5 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 16/02/2015 | 02/04/2015 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 |
6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 01/08/2012 | 17/09/2012 | Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 | Reproductive toxicity (pre-natal developmental toxicity) | 26/04/2019 | 10/06/2019 | Details | |
3-chloropropyltrimethoxysilane | 219-787-9 | 2530-87-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
2,2'-(octadec-9-enylimino)bisethanol | 246-807-3 | 25307-17-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
2,2`-(octadec-9-enylimino)bisethanol | 246-807-3 | 25307-17-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 29/08/2011 |
Details | |
Decene | 246-870-7 | 25339-53-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
2,2'-methylenediphenyl diisocyanate | 219-799-4 | 2536-05-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
Tridecene | 246-919-2 | 25377-82-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Octene | 246-920-8 | 25377-83-7 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with hex-1-ene Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Dodecene | 246-922-9 | 25378-22-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Triethoxypropylsilane | 219-842-7 | 2550-02-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
4-phenylbutan-2-one | 219-847-4 | 2550-26-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons | 22/11/2017 | 08/01/2018 | Details | |
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 219-863-1 | 2554-06-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 17/04/2014 17/04/2014 |
Details | |
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate | 247-161-5 | 25646-71-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
4,4'-Methylenediphenyl diisocyanate, oligomers | 500-040-3 | 25686-28-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine | 426-040-2 | 25713-60-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 01/08/2011 |
Details | |
Dimethyl 2,2'-azobis(2-methylpropionate) | 219-976-6 | 2589-57-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]triethoxysilane | 220-011-6 | 2602-34-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Orthoboric acid, compound with 2-aminoethanol | 247-421-8 | 26038-87-9 | Repeated dose toxicity (90-day): oral | 17/11/2011 | 02/01/2012 | Details | |
Orthoboric acid, compound with 2-aminoethanol | 247-421-8 | 26038-87-9 |
Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Bis(2-ethylhexyl) tetrabromophthalate | 247-426-5 | 26040-51-7 | Reproductive toxicity (pre-natal developmental toxicity) | 16/05/2014 | 30/06/2014 | Details | |
1,3,5-tris[3-(trimethoxysilyl)propyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 247-465-8 | 26115-70-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
1,1,3,3-tetramethyl-1,3-divinyldisiloxane | 220-099-6 | 2627-95-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Dihexadecyl peroxodicarbonate | 247-611-0 | 26322-14-5 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4) Sub-chronic toxicity (90-day): oral |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
Octanoic acid, monoester with glycerol | 247-668-1 | 26402-26-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) | 247-810-2 | 26566-95-0 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 |
Details | |
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) | 247-810-2 | 26566-95-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with another ZDDP category member to be determined based on outcome of other testing proposals Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
tert-butyl peroxyneodecanoate | 247-955-1 | 26748-41-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): dermal |
15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
26/05/2010 26/05/2010 26/05/2010 |
12/07/2010 12/07/2010 12/07/2010 |
Details | |
Diisopropylbenzene hydroperoxide | 247-988-1 | 26762-93-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
N-ethyl-2-pyrrolidone (NEP) | 220-250-6 | 2687-91-4 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
Tricyclodecanedimethanol | 248-096-5 | 26896-48-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Tetradecene | 248-130-9 | 26952-13-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Hexadecene | 248-131-4 | 26952-14-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Allyl 3-cyclohexylpropionate | 220-292-5 | 2705-87-5 | Reproductive toxicity (pre-natal developmental toxicity) | 26/10/2022 | 12/12/2022 | Details | |
di-p-tolyl(2,4,6-trimethylbenzoyl)phosphine oxide | 884-585-5 | 270586-78-2 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/06/2023 30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 14/08/2023 |
Details | |
Octadecene | 248-205-6 | 27070-58-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
Tetrakis(hydroxymethyl)phosphonium chloride, oligomeric reaction products with urea | 500-057-6 | 27104-30-9 | Sub-chronic toxicity (90-day): oral | 02/09/2011 | 17/10/2011 | Details | |
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate | 248-227-6 | 27107-89-7 | Genetic toxicity in vivo | 30/11/2015 | 14/01/2016 | Details | |
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate | 248-227-6 | 27107-89-7 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2011 16/05/2011 16/05/2011 |
30/06/2011 30/06/2011 30/06/2011 |
Details | |
α,α,α',α'-tetramethylxylene-α,α-diol | 248-256-4 | 27138-01-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
Oxydipropyl dibenzoate | 248-258-5 | 27138-31-4 | Long-term toxicity to fish | 10/08/2018 | 24/09/2018 | Details | |
Nonene | 248-339-5 | 27215-95-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
2-ethylhexyl nitrate | 248-363-6 | 27247-96-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
29/04/2011 29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 14/06/2011 |
Details | |
Neodecanoic acid, cobalt salt | 248-373-0 | 27253-31-2 | Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant | 21/01/2021 | 08/03/2021 | Details | |
Neodecanoic acid, cobalt salt | 248-373-0 | 27253-31-2 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) | 28/11/2022 | 12/01/2023 | Details | |
Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (pre-natal developmental toxicity) | 20/12/2017 | 05/02/2018 | Details | |
Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2020 | 01/02/2021 | Details | |
Vanadium oxide sulphate | 248-652-7 | 27774-13-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with sodium metavanadate (EC 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with sodium metavanadate (EC 237-272-7) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
Benzyltoluene | 248-654-8 | 27776-01-8 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2014 | 04/04/2014 | Details | |
Benzyltoluene | 248-654-8 | 27776-01-8 | Long-term toxicity to fish (OECD 210) | 25/06/2019 | 09/08/2019 | Details | |
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate | 220-482-8 | 2781-11-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form | 220-509-3 | 2786-76-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) | 03/10/2023 | 17/11/2023 | Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate | 248-882-8 | 28173-59-3 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
Ditolyl ether | 248-948-6 | 28299-41-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/10/2021 21/10/2021 |
07/12/2021 07/12/2021 |
Details | |
Diisodecyl sebacate | 249-047-0 | 28473-19-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Di-''isononyl'' phthalate | 249-079-5 | 28553-12-0 | Reproductive toxicity (pre-natal developmental toxicity) | 22/09/2022 | 07/11/2022 | Details | |
Zinc bis(O,O-diisooctyl) bis(dithiophosphate) | 249-109-7 | 28629-66-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Zinc bis(O,O-diisooctyl) bis(dithiophosphate) | 249-109-7 | 28629-66-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
3-(isodecyloxy)propylammonium acetate | 249-166-8 | 28701-67-9 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
Tetrasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(6-sulphonato-2-naphthyl)azo]naphthalene-2-sulphonate] | 249-171-5 | 28706-25-4 | Reproductive toxicity (pre-natal developmental toxicity) | 10/05/2022 | 27/06/2022 | Details | |
N-(1,1-dimethyl-3-oxobutyl)acrylamide | 220-713-2 | 2873-97-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] | 249-204-3 | 28768-32-3 |
Reproduction toxicity (two generation reproductive toxicity) Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): dermal |
26/01/2011 26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 14/03/2011 |
Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane | 220-780-8 | 2897-60-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 16/12/2016 | 30/01/2017 | Details | |
methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Sub-chronic toxicity (90-day): oral | 16/12/2020 | 01/02/2021 | Details | |
methyl-1h-benzotriazole | 249-596-6 | 29385-43-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate | 16/12/2016 | 30/01/2017 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 | Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) | 17/04/2015 | 04/06/2015 | Details | |