Anterioare/Rezultat
Anterioare/Rezultat
Anterioare/Rezultat
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
6,15-dihydroanthrazine-5,9,14,18-tetrone | 201-375-5 | 81-77-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol | 204-327-1 | 119-47-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
6,6`-di-tert-butyl-2,2`-methylenedi-p-cresol | 204-327-1 | 119-47-1 | Reproductive toxicity (two-generation reproductive toxicity) | 16/05/2011 | 30/06/2011 | Details | |
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene) | 807-130-4 | 53716-82-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione | 244-320-0 | 21295-57-8 | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1) | 701-138-0 | 242482-67-3 | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
6-[(1-oxomethyloctyl)amino]hexanoic acid | 276-173-3 | 71902-23-3 | Reproductive toxicity (pre-natal developmental toxicity) | 10/03/2017 | 25/04/2017 | Details | |
6-methyl-1,3,5-triazine-2,4-diyldiamine | 208-796-3 | 542-02-9 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
6-phenyl-1,3,5-triazine-2,4-diamine | 202-095-6 | 91-76-9 | Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) | 12/06/2013 | 29/07/2013 | Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 | Long-term toxicity to fish | 15/07/2014 | 29/08/2014 | Details | |
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate | 276-957-5 | 72869-86-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt | 429-070-4 | - | Sub-chronic toxicity (90-day): oral | 22/04/2021 | 07/06/2021 | Details | |
7-hydroxycitronellal | 203-518-7 | 107-75-5 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
8,9,10,11-tetrachloro-12H-phthaloperin-12-one | 244-007-9 | 20749-68-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
8,9,10-trinorborn-2-ene | 207-866-0 | 498-66-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/11/2015 01/11/2015 |
16/12/2015 16/12/2015 |
Details | |
8,9,10-trinorborn-2-ene | 207-866-0 | 498-66-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 |
Details | |
9-Octadecenoic acid (Z)-, sulfonated, potassium salts | 271-843-1 | 68609-93-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 20/04/2012 |
Details | |
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant |
20/10/2016 20/10/2016 |
05/12/2016 05/12/2016 |
Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” | 25/05/2020 | 09/07/2020 | Details | |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2012 16/05/2012 16/05/2012 |
02/07/2012 02/07/2012 02/07/2012 |
Details | |
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane | 216-365-6 | 1565-76-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
[1α(E),2β]-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one | 275-156-8 | 71048-82-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/10/2022 | 12/12/2022 | Details | |
[3-(2,3-epoxypropoxy)propyl]triethoxysilane | 220-011-6 | 2602-34-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 01/08/2012 | 17/09/2012 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 |
6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 16/02/2015 | 02/04/2015 | Details | |
[3-(triethoxysilyl)propyl]urea | 245-876-7 | 23779-32-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 |
Details | |
[3-(trimethoxysilyl)propyl]urea | 245-904-8 | 23843-64-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant | 07/07/2020 | 21/08/2020 | Details | |
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan | 229-861-2 | 6790-58-5 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
[4-[p,p'-bis(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium m-[[p-anilinophenyl]azo]benzenesulphonate | 265-449-9 | 65113-55-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 04/04/2014 |
Details | |
[[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt | 274-798-6 | 70714-66-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) | 01/03/2023 | 17/04/2023 | Details | |
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant. |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt | 254-135-7 | 38820-59-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
[No public or meaningful name is available] | 944-258-0 | 1850357-57-1 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) | 03/05/2023 | 19/06/2023 | Details | |
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. | 943-834-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
A mixture of isomers of branched tetracosane | 417-060-2 | 151006-61-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
01/07/2021 01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 16/08/2021 |
Details | |
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate | 403-500-0 | 159120-95-3 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 |
(90-day): oral Reproductive toxicity (developmental toxicity) Sub-chronic toxicity |
20/10/2010 20/10/2010 20/10/2010 |
06/12/2010 06/12/2010 06/12/2010 |
Details | |
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate | 413-750-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate | 410-800-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 |
Details | |
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) | 04/12/2023 | 18/01/2024 | Details | |
A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) | 400-830-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2011 | 30/01/2012 | Details | |