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EC number: 203-458-1
CAS number: 107-06-2
In an acute oral toxicity study, groups of fasted (18
hours), 6 -week-old CD-1 mice were given a single oral dose of 1,2
-dichloroethane and observed for 14 days.
The mice died over a 48 -hour period. Those surviving 48
hours recovered and appeared normal at the end of the 14 -days
observation period. Macroscopically, target organs appeared to be liver
and lungs. The calculated LD50 values using log probit analysis were 489
mg/kg bw (95% C.I. 424 -552 mg/kg bw) and 413 mg/kg bw (95% C.I. 337-499
mg/kg bw) for male and female mice, respectively.
1,2 -dichloroethane is of low acute oral toxicity based
on the LD50 in male and female CD-1 mice.
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