Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-458-1
CAS number: 107-06-2
Based on a statistically significant reduction of fish weight the MATC (maximum acceptable toxicant concentration) of 1,2-dichloroethane in a fathead minnow early life stage test was 29 - 59 mg/L based on measured concentrations.
The key study was selected as the study
shows the lowest toxicity endpoint.
The effects of 1,2-dichloroethane on the
early life stages of fathead minnow (Pimephales promelas) were
determined under continuous-flow conditions for 32 days. A dilution
water control and nominal test item concentrations of 4.0, 7.0, 14.0,
29.0, and 59.0 mg/L were used during the study.
Based on a statistically significant
reduction of fish weight the MATC (maximum acceptable toxicant
concentration) of 1,2-dichloroethane in a fathead minnow early life
stage test was 29 - 59 mg/L on measured concentrations.
Further on, the following additional
information on long-term toxicity to fish is available, but is not
considered as reliable:
56 mg/L (LOEC) after 21 d
Reid, B.J.et al.(1982)
0.2 mg/L after 27 d
Black, J.Aet al.(1982)
The effect values found by Black et al. for
several substances are usually very low compared to effect values by
other authors. No explanation for these large discrepancies could be
found. A careful examination of the entire information provided by Black
et al. gave no plausible reason for the inconsistency of the data.
However, as it was not possible to reproduce the effect values found by
Black and his co-workers, it is proposed not to use these data for a
derivation of a PNECaqua if other valid fish early life stage tests are
Black, J.A. et al. (1982): NTIS/PB
Reid, B.J. Morgan J.D., Whelen, M.A. (1982):
A preliminary examination of the effects of ethylene dichloride on the
hatchability of coho salmon eggs (oncorhynchus kisutch); Can. Techn.
Rep. Fish. Aquat. Sci. 1163, 145-153.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Deze website maakt gebruik van cookies om het surfen zo aangenaam mogelijk te maken.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again