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EC number: 203-458-1
CAS number: 107-06-2
Based on a statistically significant reduction of fish weight the MATC (maximum acceptable toxicant concentration) of 1,2-dichloroethane in a fathead minnow early life stage test was 29 - 59 mg/L based on measured concentrations.
The key study was selected as the study
shows the lowest toxicity endpoint.
The effects of 1,2-dichloroethane on the
early life stages of fathead minnow (Pimephales promelas) were
determined under continuous-flow conditions for 32 days. A dilution
water control and nominal test item concentrations of 4.0, 7.0, 14.0,
29.0, and 59.0 mg/L were used during the study.
Based on a statistically significant
reduction of fish weight the MATC (maximum acceptable toxicant
concentration) of 1,2-dichloroethane in a fathead minnow early life
stage test was 29 - 59 mg/L on measured concentrations.
Further on, the following additional
information on long-term toxicity to fish is available, but is not
considered as reliable:
56 mg/L (LOEC) after 21 d
Reid, B.J.et al.(1982)
0.2 mg/L after 27 d
Black, J.Aet al.(1982)
The effect values found by Black et al. for
several substances are usually very low compared to effect values by
other authors. No explanation for these large discrepancies could be
found. A careful examination of the entire information provided by Black
et al. gave no plausible reason for the inconsistency of the data.
However, as it was not possible to reproduce the effect values found by
Black and his co-workers, it is proposed not to use these data for a
derivation of a PNECaqua if other valid fish early life stage tests are
Black, J.A. et al. (1982): NTIS/PB
Reid, B.J. Morgan J.D., Whelen, M.A. (1982):
A preliminary examination of the effects of ethylene dichloride on the
hatchability of coho salmon eggs (oncorhynchus kisutch); Can. Techn.
Rep. Fish. Aquat. Sci. 1163, 145-153.
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