Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1,001 - 1,050 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
2-phenoxyethyl acrylate	256-360-6	48145-04-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate	255-901-3	42594-17-2	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate	255-901-3	42594-17-2	Bioaccumulation test (Bioconcentration: Flow-through Fish Test) Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020 23/03/2020	07/05/2020 07/05/2020	Details
1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone	255-460-7	41611-76-1	Reproductive toxicity (pre-natal developmental toxicity)	04/04/2014	19/05/2014	Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate	255-180-5	41026-17-9	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014 16/05/2014 16/05/2014	30/06/2014 30/06/2014 30/06/2014 30/06/2014	Details
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate	255-180-5	41026-17-9	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2016 16/12/2016 16/12/2016	30/01/2017 30/01/2017 30/01/2017	Details
1,3,5-tris[[4-tert-butyl-3-hydroxy-2,6-xylyl]methyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione	254-996-9	40601-76-1	Reproductive toxicity (pre-natal developmental toxicity) with Rat	24/07/2019	09/09/2019	Details
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate	254-959-7	40530-60-7	Genetic toxicity in vivo \|\| Note: testing proposed with Disperse Red 302:1 (EC 248-882-8)	23/11/2020	07/01/2021	Details
2-(2-thienyl)ethyl toluene-p-sulphonate	254-911-5	40412-06-4	Genetic toxicity in vivo	06/09/2018	22/10/2018	Details
(2,4,6-trioxo-1,3,5-triazine-1,3,5(2H,4H,6H)-triyl)tri-2,1-ethanediyl triacrylate	254-843-6	40220-08-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate	254-588-0	39670-09-2	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
Phosphoric acid, octadecyl ester	254-466-7	39471-52-8	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/04/2015 17/04/2015 17/04/2015 17/04/2015	04/06/2015 04/06/2015 04/06/2015 04/06/2015	Details
Phosphoric acid, dodecyl ester, potassium salt	254-414-3	39322-78-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
(phenylethyl)benzene	254-179-7	38888-98-1	Reproductive toxicity (pre-natal developmental toxicity)	21/03/2014	05/05/2014	Details
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt	254-135-7	38820-59-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
1,1'-(p-tolylimino)dipropan-2-ol	254-075-1	38668-48-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/03/2016 17/04/2015	28/04/2016 04/06/2015	Details
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate	253-981-4	38517-37-2	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) \|\| Note: Testing proposal is based on concern identified by the registrant.	17/12/2019	31/01/2020	Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride	253-781-7	38103-06-9	Sub-chronic toxicity (90-day): oral	27/01/2020	12/03/2020	Details
2-phosphonobutane-1,2,4-tricarboxylic acid	253-733-5	37971-36-1	Long-term toxicity to fish\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
2,4-Pentanedione, peroxide	253-384-9	37187-22-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine	252-899-6	36177-92-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): ora	07/10/2016 07/10/2016	21/11/2016 21/11/2016	Details
N,N''-propane-1,3-diylbis[N'-octadecylurea	252-667-4	35674-65-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	29/03/2016	13/05/2016	Details
Triethoxy(2,4,4-trimethylpentyl)silane	252-558-1	35435-21-3	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Triethoxy(2,4,4-trimethylpentyl)silane	252-558-1	35435-21-3	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Trinonyl benzene-1,2,4-tricarboxylate	252-552-9	35415-27-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	11/11/2016 11/11/2016	03/01/2017 03/01/2017	Details
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate	252-173-9	34730-59-1	Reproductive toxicity (pre-natal developmental toxicity)	29/04/2014	13/06/2014	Details
triethoxy(3-thiocyanatopropyl)silane	252-161-3	34708-08-2	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid	252-156-6	34690-00-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposal is based on concern identified by the registrant.	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid	252-156-6	34690-00-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
Tris(nitrato-O)nitrosylruthenium	252-068-8	34513-98-9	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide	252-046-8	34455-29-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide	252-046-8	34455-29-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate	252-029-5	34443-12-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014 21/03/2014	05/05/2014 05/05/2014 05/05/2014	Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate	252-029-5	34443-12-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/01/2021 21/01/2021	08/03/2021 08/03/2021	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Sub-chronic toxicity (90-day): oral Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) "	25/06/2015	10/08/2015	Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1)	251-846-4	34140-91-5	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Sodium hexahydroxoantimonate	251-735-0	33908-66-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011	29/08/2011 29/08/2011	Details
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one	251-649-3	33704-61-9	Reproductive toxicity (pre-natal developmental toxicity)	30/06/2023	14/08/2023	Details
Diisononyl adipate	251-646-7	33703-08-1	Long-term toxicity to fish\|\|Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)	03/05/2023 03/05/2023	19/06/2023 19/06/2023	Details
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine	251-459-0	33329-35-0	Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound	29/04/2014	13/06/2014	Details
3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-cyclododeca[b]pyran	251-090-5	32539-83-6	Genetic toxicity in vivo	14/02/2011	31/03/2011	Details
Ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate]	251-073-2	32509-66-3	Reproductive toxicity (pre-natal developmental toxicity)	31/01/2014	17/03/2014	Details
4-tert-butylcyclohexyl acetate	250-954-9	32210-23-4	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate	24/02/2020	09/04/2020	Details
Tris(2,4-ditert-butylphenyl) phosphite	250-709-6	31570-04-4	Reproductive toxicity (pre-natal developmental toxicity)	28/11/2022	12/01/2023	Details
Potassium 3-sulphonatopropyl acrylate	250-465-0	31098-20-1	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
N-[3-(trimethoxysilyl)propyl]butylamine // Note: testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC No. 217-164-6)	250-437-8	31024-56-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate	250-418-4	30989-05-0	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	28/02/2011 28/02/2011 28/02/2011	14/04/2011 14/04/2011 14/04/2011	Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate	250-418-4	30989-05-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details

Showing 1,001 - 1,050 of 2,011 results.

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