Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Resin acids and Rosin acids, hydrogenated, esters with glycerol | 266-042-9 | 65997-13-9 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
Rosin, hydrogenated | 266-041-3 | 65997-06-0 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
Rosin, hydrogenated | 266-041-3 | 65997-06-0 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7) Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin (CAS RN 8050-09-7) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) |
02/07/2013 02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 16/08/2013 |
Details | |
Rosin, fumarated | 266-040-8 | 65997-04-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with the registered substance (CAS RN 65997-04-7) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
06/03/2012 02/07/2013 02/07/2013 02/07/2013 |
20/04/2012 16/08/2013 16/08/2013 16/08/2013 |
Details | |
Slimes and Sludges, blast furnace and steelmaking | 266-006-2 | 65996-73-8 | Genetic toxicity in vivo||Note: testing proposed with Iron (EC no. 231-096-4), Calcium oxide (EC no. 215-138-9), Magnesium oxide (EC no. 215-171-9), Zinc (EC no. 231-175-3) and Manganese (EC no. 231-105-1) | 30/06/2023 | 14/08/2023 | Details | |
Slimes and Sludges, blast furnace and steelmaking | 266-006-2 | 65996-73-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Dust, steelmaking | 266-005-7 | 65996-72-7 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2011 | 15/08/2011 | Details | |
[4-[p,p'-bis(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium m-[[p-anilinophenyl]azo]benzenesulphonate | 265-449-9 | 65113-55-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 04/04/2014 |
Details | |
Paraffins (petroleum), normal C>10 | 265-232-9 | 64771-71-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Solvent naphtha (petroleum), heavy arom. | 265-198-5 | 64742-94-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
Asphalt, oxidized | 265-196-4 | 64742-93-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Asphalt, oxidized | 265-196-4 | 64742-93-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2019 | 09/08/2019 | Details | |
Asphalt, oxidized | 265-196-4 | 64742-93-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
18/02/2013 18/02/2013 |
04/04/2013 04/04/2013 |
Details | |
Gas oils (petroleum), hydrodesulfurized light vacuum | 265-190-1 | 64742-87-6 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Gas oils (petroleum), hydrodesulfurized light vacuum | 265-190-1 | 64742-87-6 |
Genetic toxicity in vivo
|| Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2) Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity) 1st (Rat) and 2nd species (Rabbit) (Dermal route)
|| Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2) Sub-chronic toxicity (90 day): dermal
|| Note: testing proposed with category members
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Residues (petroleum), hydrodesulfurized vacuum | 265-188-0 | 64742-85-4 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0) Reproductive toxicity (two-generation reproductive toxicity) || Note: test proposed with a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0) |
04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 |
Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 | Genetic toxicity in vivo | 14/05/2020 | 29/06/2020 | Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrodesulfurized middle | 265-183-3 | 64742-80-9 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Gas oils (petroleum), hydrodesulfurized | 265-182-8 | 64742-79-6 | Genetic toxicity in vivo | 14/05/2020 | 29/06/2020 | Details | |
Gas oils (petroleum), hydrodesulfurized | 265-182-8 | 64742-79-6 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Gas oils (petroleum), hydrodesulfurized | 265-182-8 | 64742-79-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), hydrotreated middle | 265-148-2 | 64742-46-7 | Genetic toxicity in vivo | 14/05/2020 | 29/06/2020 | Details | |
Extracts (petroleum), residual oil solvent | 265-110-5 | 64742-10-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 06/06/2023 | 21/07/2023 | Details | |
Extracts (petroleum), residual oil solvent | 265-110-5 | 64742-10-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
Extracts (petroleum), residual oil solvent | 265-110-5 | 64742-10-5 | Reproductive toxicity (two-generation reproductive toxicity) | 16/05/2011 | 30/06/2011 | Details | |
Extracts (petroleum), heavy naphtha solvent | 265-099-7 | 64741-98-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
Distillates (petroleum), sweetened middle | 265-088-7 | 64741-86-2 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), light hydrocracked | 265-078-2 | 64741-77-1 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), light hydrocracked | 265-078-2 | 64741-77-1 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Gas oils (petroleum), light vacuum | 265-059-9 | 64741-58-8 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal Sub-chronic toxicity (90-day): oral |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Gas oils (petroleum), light vacuum | 265-059-9 | 64741-58-8 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Residues (petroleum), vacuum | 265-057-8 | 64741-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2019 | 09/08/2019 | Details | |
Residues (petroleum), vacuum | 265-057-8 | 64741-56-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Residues (petroleum), vacuum | 265-057-8 | 64741-56-6 |
Genetic toxicity in vivo||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Asphalt (EC no. 232-490-9) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Asphalt (EC no. 232-490-9) |
04/12/2023 04/12/2023 04/12/2023 04/12/2023 |
18/01/2024 18/01/2024 18/01/2024 18/01/2024 |
Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 |
Genetic toxicity in vivo
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuels, diesel (EC 269-822-7)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2)
- Fuels, diesel (EC 269-822-7) Sub-chronic toxicity (90 day): dermal
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Distillates (petroleum), straight-run middle | 265-044-7 | 64741-44-2 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Distillates (petroleum), straight-run middle | 265-044-7 | 64741-44-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) | 23/11/2020 | 07/01/2021 | Details | |
Gas oils (petroleum), straight-run | 265-043-1 | 64741-43-1 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
Sodium 4(or 5)-methyl-1H-benzotriazolide | 265-004-9 | 64665-57-2 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with Tolyltriazole (EC 249-596-6) | 16/12/2020 | 01/02/2021 | Details | |
Sodium 4(or 5)-methyl-1H-benzotriazolide | 265-004-9 | 64665-57-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either Benzotriazole, Tolyltriazole, Sodium Benzotriazolate, or Sodium Tolyltriazolate | 16/12/2016 | 30/01/2017 | Details | |
Yttrium zirconium oxide | 264-885-7 | 64417-98-7 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2014 | 13/06/2014 | Details | |
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol | 264-848-5 | 64365-17-9 |
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9) Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7) |
02/07/2013 02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 16/08/2013 |
Details | |
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol | 264-848-5 | 64365-17-9 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant | 21/01/2021 | 08/03/2021 | Details | |
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine | 264-761-2 | 64265-45-8 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate | 264-513-3 | 63843-89-0 | Genetic toxicity in vivo | 29/04/2014 | 13/06/2014 | Details | |