Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 901 - 950 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Dichlorobis(η-cyclopentadienyl)titanium	215-035-9	1271-19-8	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
dichlorocyclohexylmethylsilane	226-956-0	5578-42-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0)	16/03/2015	30/04/2015	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/06/2017	07/08/2017	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (pre-natal developmental toxicity)	31/01/2014	17/03/2014	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (pre-natal developmental toxicity)	15/09/2011	31/10/2011	Details
Dicyclohexylamine	202-980-7	101-83-7	Genetic toxicity in vivo (mammalian bone marrow chromosome aberration test) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/03/2011 15/03/2011 15/03/2011 15/03/2011	29/04/2011 29/04/2011 29/04/2011 29/04/2011	Details
Dicyclopentyldimethoxysilane	404-370-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/12/2011 16/12/2011 16/12/2011	30/01/2012 30/01/2012 30/01/2012	Details
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate	220-482-8	2781-11-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	27/01/2020	12/03/2020	Details
Diethyl carbonate	203-311-1	105-58-8	Genetic toxicity in vivo	18/02/2014	04/04/2014	Details
Diethyl ether	200-467-2	60-29-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	02/11/2018	17/12/2018	Details
diethyl ether	200-467-2	60-29-7	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011	29/08/2011	Details
Diethyl ethylphosphonate	201-111-9	78-38-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
Diethylamine	203-716-3	109-89-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dimethylamine (CAS 124-40-3)	21/09/2020	05/11/2020	Details
Diethylmethylbenzenediamine	270-877-4	68479-98-1	Long-term toxicity to fish	04/12/2023	18/01/2024	Details
Diethylmethylbenzenediamine	270-877-4	68479-98-1	Reproductive toxicity (pre-natal developmental toxicity)	29/07/2011	12/09/2011	Details
Dihexadecyl peroxodicarbonate	247-611-0	26322-14-5	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4) Sub-chronic toxicity (90-day): oral	23/04/2018 23/04/2018	07/06/2018 07/06/2018	Details
dihydro-3-(tripropenyl)furan-2,5-dione	295-556-6	92077-08-2	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015	16/11/2015	Details
Dihydrogen hexahydroxyplatinate	257-471-2	51850-20-5	Genetic toxicity in vivo \|\| Note: testing proposed with dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) (EC 268-717-3)	21/12/2021	04/02/2022	Details
Dihydrogen hexahydroxyplatinate	257-471-2	51850-20-5	Genetic toxicity in vivo \|\| Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant.	28/02/2018	16/04/2018	Details
Dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2)	268-717-3	68133-90-4	Genetic toxicity in vivo	21/12/2021	04/02/2022	Details
Dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2)	268-717-3	68133-90-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	04/10/2018	19/11/2018	Details
Diisodecyl sebacate	249-047-0	28473-19-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Diisononyl adipate	251-646-7	33703-08-1	Long-term toxicity to fish\|\|Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)	03/05/2023 03/05/2023	19/06/2023 19/06/2023	Details
Diisopentyl ether	208-857-4	544-01-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	18/02/2014 18/02/2014 18/02/2014	04/04/2014 04/04/2014 04/04/2014	Details
Diisopropyl ether	203-560-6	108-20-3	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011	29/08/2011	Details
Diisopropylbenzene hydroperoxide	247-988-1	26762-93-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Dilauroyl peroxide	203-326-3	105-74-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
dimethoxydimethylsilane	214-189-4	1112-39-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
dimethoxydimethylsilane	214-189-4	1112-39-6	Sub-chronic toxicity (90 day): inhalation	16/10/2014	01/12/2014	Details
dimethoxydiphenylsilane	229-929-1	6843-66-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Dimethoxymethane	203-714-2	109-87-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
dimethoxymethylsilane	240-914-9	16881-77-9	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with trimethoxy(methyl)silane.	16/10/2014	01/12/2014	Details
Dimethoxymethylsilane	240-914-9	16881-77-9	Sub-chronic toxicity (90-day): oral	25/05/2020	09/07/2020	Details
Dimethyl (p-methoxybenzylidene)malonate	231-185-8	7443-25-6	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	23/03/2020	07/05/2020	Details
Dimethyl 2,2'-azobis(2-methylpropionate)	219-976-6	2589-57-3	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
Dimethyl cyclohexane-1,4-dicarboxylate	202-347-5	94-60-0	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2014	30/05/2014	Details
Dimethyl sebacate	203-431-4	106-79-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2014 31/01/2014 31/01/2014	17/03/2014 17/03/2014 17/03/2014	Details
Dimethyl sulfoxide	200-664-3	67-68-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	31/01/2023	17/03/2023	Details
Dimethyl(propyl)amine	213-139-9	926-63-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Ethyldimethylamine (EC 209-940-8)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
Dimethylamine	204-697-4	124-40-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
Dimethylpropane-1,3-diol	204-781-0	126-30-7	Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day)	26/01/2011 26/01/2011	14/03/2011 14/03/2011	Details
Dioctadecyl 3,3'-thiodipropionate	211-750-5	693-36-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	03/04/2023	22/05/2023	Details
Dioctyltin dilaurate	222-883-3	3648-18-8	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
Dioxydibutane-2,2-diyl dihydroperoxide	215-661-2	1338-23-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Diphenyl sulphone	204-853-1	127-63-9	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014	04/04/2014	Details
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide	278-355-8	75980-60-8	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014	04/04/2014	Details
Diphosphoric acid, compd. with piperazine (1:1)	457-330-7	66034-17-1	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022 10/05/2022	27/06/2022 27/06/2022 27/06/2022	Details
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine	239-590-1	15541-60-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer	234-293-3	11071-15-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
dipotassium heptafluorotantalate	240-986-1	16924-00-8	Genetic toxicity in vivo	16/03/2015	30/04/2015	Details

Showing 901 - 950 of 2,011 results.

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