Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |
| Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
| Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide | 939-459-5 | - | Sub-chronic toxicity (90-day): oral | 30/11/2015 | 14/01/2016 | Details | |
| Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction | 949-141-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
| Saccharomyces cerevisiae cell wall, extracted | 949-711-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
| Shale oils, heavy | 930-690-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 14/03/2016 14/03/2016 |
02/01/2012 28/04/2016 28/04/2016 |
Details | |
| Shale oils, light | 923-592-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” | 14/03/2016 | 28/04/2016 | Details | |
| Shale oils, light | 923-592-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 17/11/2011 17/11/2011 |
02/01/2012 02/01/2012 02/01/2012 |
Details | |
| Slags, steelmaking, elec. furnace (stainless/high alloy steel production) | 932-476-9 | - | Sub-chronic toxicity (90 day): inhalation | 06/03/2012 | 20/04/2012 | Details | |
| Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) | 947-369-2 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
| Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed | 941-809-7 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |
| Soybean oil, oligomerized | 701-252-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/09/2018 | 22/10/2018 | Details | |
| SUMILIZER GP | 442-450-4 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |
| Terpenic base | 947-968-9 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
| terpenic oligomers | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/10/2022 | 12/12/2022 | Details | |
| Tetraammineplatinum (II) diacetate | 457-310-8 | - | Genetic toxicity in vivo (COMET, OECD TG 489) || Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9). | 22/06/2017 | 07/08/2017 | Details | |
| tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate | 474-870-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
| Trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide | 700-597-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
18/06/2012 18/06/2012 |
02/08/2012 02/08/2012 |
Details | |
| Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate | 700-316-5 | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-days): oral |
11/01/2011 11/01/2011 |
25/02/2011 25/02/2011 |
Details | |
| Trimethylolpropane and its reaction products with methyloxirane | 957-630-2 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
| Tris({[(hydroxyalkyl)amino]oxy}-oxoalkyl)-triazaalkanoic acid and water | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 12/06/2013 | 29/07/2013 | Details | |
| trisodium 2-(2-sulfoethoxy)ethane-1-sulfonate ethenesulfonate | 700-978-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) Note: testing proposed with Sodium ethylenesulphonate (EC No. 221-242-5) | 03/05/2023 | 19/06/2023 | Details | |
| tri{[(2s)-1-ethoxy-1-oxopropan-2-yl]oxy}(vinyl)silane | 701-301-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
| Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl | 445-760-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/07/2015 31/07/2015 |
14/09/2015 14/09/2015 |
Details | |
| Residues (petroleum), thermal cracked vacuum | 295-518-9 | 062-05-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) | 25/06/2019 | 09/08/2019 | Details | |
| 1,4-diisopropylbenzene | 202-826-9 | 100-18-5 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS no. 99-62-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with CAS no. 99-62-7 |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
| Terephthalic acid | 202-830-0 | 100-21-0 | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2020 | 01/02/2021 | Details | |
| Ethylbenzene | 202-849-4 | 100-41-4 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
| Styrene | 202-851-5 | 100-42-5 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
| Styrene | 202-851-5 | 100-42-5 | Long-term toxicity to fish | 04/09/2023 | 19/10/2023 | Details | |
| N-methylaniline | 202-870-9 | 100-61-8 |
Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
01/07/2011 01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 15/08/2011 |
Details | |
| N-methylaniline | 202-870-9 | 100-61-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): dermal |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
| Anisole | 202-876-1 | 100-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
| 2,2-dimethyl-1,3-dioxolan-4-ylmethanol | 202-888-7 | 100-79-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 |
Details | |
| 2,2-dimethyl-1,3-dioxolan-4-ylmethanol | 202-888-7 | 100-79-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
| Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate | 600-028-9 | 1001254-87-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): dermal |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-amino-4-octanol | 482-070-6 | 1001354-72-8 | Reproductive toxicity (developmental toxicity) | 19/11/2010 | 03/01/2011 | Details | |
| 1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. | 600-033-6 | 1001416-18-7 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
| 1-ethoxy-2-(2-methoxyethoxy)ethane | 213-690-5 | 1002-67-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 09/07/2020 |
Details | |
| Dipotassium tetrachloroplatinate | 233-050-9 | 10025-99-7 | Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." | 18/06/2018 | 02/08/2018 | Details | |
| d-Glucose, ether with glycerol | 309-496-6 | 100402-60-6 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| Strontium nitrate | 233-131-9 | 10042-76-9 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 15/07/2011 |
Details | |
| Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine | 309-629-8 | 100545-48-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
| Residues (petroleum), distn. residue hydrogenation | 309-712-9 | 100684-39-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Residues (petroleum), vacuum distn. residue hydrogenation | 309-713-4 | 100684-40-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| 4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline | 233-215-5 | 10081-67-1 | Sub-chronic toxicity (90-day): oral | 18/02/2014 | 04/04/2014 | Details | |
| a,a-dimethylphenethyl butyrate | 233-221-8 | 10094-34-5 |
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
| 2,4,6-triallyloxy-1,3,5-triazine | 202-936-7 | 101-37-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
| 4,4'-methylenediphenyl diisocyanate | 202-966-0 | 101-68-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/11/2021 | 10/01/2022 | Details | |
| Dicyclohexylamine | 202-980-7 | 101-83-7 |
Genetic toxicity in vivo (mammalian bone marrow chromosome aberration test) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/03/2011 15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 29/04/2011 |
Details | |