Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1,101 - 1,150 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
diethyl ether	200-467-2	60-29-7	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011	29/08/2011	Details
Diethyl ether	200-467-2	60-29-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	02/11/2018	17/12/2018	Details
Diethyl carbonate	203-311-1	105-58-8	Genetic toxicity in vivo	18/02/2014	04/04/2014	Details
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate	220-482-8	2781-11-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	27/01/2020	12/03/2020	Details
Dicyclopentyldimethoxysilane	404-370-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/12/2011 16/12/2011 16/12/2011	30/01/2012 30/01/2012 30/01/2012	Details
Dicyclohexylamine	202-980-7	101-83-7	Genetic toxicity in vivo (mammalian bone marrow chromosome aberration test) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/03/2011 15/03/2011 15/03/2011 15/03/2011	29/04/2011 29/04/2011 29/04/2011 29/04/2011	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/06/2017	07/08/2017	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (pre-natal developmental toxicity)	31/01/2014	17/03/2014	Details
Dichloromethylbenzene	249-854-8	29797-40-8	Reproductive toxicity (pre-natal developmental toxicity)	15/09/2011	31/10/2011	Details
dichlorocyclohexylmethylsilane	226-956-0	5578-42-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0)	16/03/2015	30/04/2015	Details
Dichlorobis(η-cyclopentadienyl)titanium	215-035-9	1271-19-8	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
Dichloro(methyl)(phenyl)silane	205-746-2	149-74-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1)	04/04/2014	19/05/2014	Details
dichloro(diphenyl)silane	201-251-0	80-10-4	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9) Sub-chronic toxicity (90-day): oral Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
dichloro(3-chloropropyl)methylsilane	232-136-3	7787-93-1	Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6, CAS 5089-70-3)	16/10/2014	01/12/2014	Details
Dibutyl itaconate	218-451-9	2155-60-4	Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
Dibutyl hydrogen phosphate	203-509-8	107-66-4	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Dibutyl fumarate	203-327-9	105-75-9	Long-term toxicity to fish	16/05/2011	30/06/2011	Details
Dibismuth trioxide	215-134-7	1304-76-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Dibenzoyl peroxide	202-327-6	94-36-0	Reproductive toxicity (pre-natal developmental toxicity)	16/06/2011	01/08/2011	Details
Dibenzoyl peroxide	202-327-6	94-36-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
diammonium hexanitratocerate	240-827-6	16774-21-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cerium (III) nitrate (CAS 10294-41-4)	20/05/2015	06/07/2015	Details
Diammonium hexachloroplatinate	240-973-0	16919-58-7	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/04/2018	07/06/2018	Details
Diammonium dihydrogen ethylenediaminetetraacetate	244-063-4	20824-56-0	Sub-chronic toxicity (90 day): inhalation	29/07/2011	12/09/2011	Details
Diamminediisocyanatozinc	401-610-3	122012-52-6	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Dialkyl-methyl-dihydro-heteropolycyle	815-131-6	913171-06-9	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/03/2020	07/05/2020	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/03/2023 01/03/2023 01/03/2023	17/04/2023 17/04/2023 17/04/2023	Details
Di-tert-butyl peroxide	203-733-6	110-05-4	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/07/2011 01/07/2011 01/07/2011	15/08/2011 15/08/2011 15/08/2011	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2011	15/08/2011	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Bioaccumulation aquatic / sediment	25/06/2019	09/08/2019	Details
di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide	201-128-1	78-63-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/10/2011 14/10/2011	28/11/2011 28/11/2011	Details
di-p-tolyl(2,4,6-trimethylbenzoyl)phosphine oxide	884-585-5	270586-78-2	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/06/2023 30/06/2023 30/06/2023	14/08/2023 14/08/2023 14/08/2023	Details
Di-''isononyl'' phthalate	249-079-5	28553-12-0	Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022	07/11/2022	Details
Di(tetraethylammonium)hexahydroxoplatinate(IV)	848-537-7	1912392-88-1	Genetic toxicity in vivo	21/09/2020	05/11/2020	Details
di(morpholin-4-yl) disulphide	203-103-0	103-34-4	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Destillation fraction of chlorosilanes	700-717-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/05/2012 16/05/2012	02/07/2012 02/07/2012	Details
Decene, hydroformylation products, high boiling	935-454-7	-	Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Decene	246-870-7	25339-53-1	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
Decane	204-686-4	124-18-5	Reproductive toxicity (two-generation reproductive toxicity)	25/06/2012	09/08/2012	Details
Decanal	203-957-4	112-31-2	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
decamethyltetrasiloxane	205-491-7	141-62-8	Reproductive toxicity (pre-natal developmental toxicity)	16/10/2014	01/12/2014	Details
Decamethylenediamine	211-471-9	646-25-3	Reproductive toxicity (pre-natal developmental toxicity)	03/03/2014	17/04/2014	Details
Decamethylcyclopentasiloxane	208-764-9	541-02-6	Reproductive toxicity (pre-natal developmental toxicity)	25/10/2017	11/12/2017	Details
Decahydronaphthalene	202-046-9	91-17-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
decahydronaphthalene	202-046-9	91-17-8	Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011	29/08/2011	Details
Dec-1-ene	212-819-2	872-05-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
d-Glucose, ether with glycerol	309-496-6	100402-60-6	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol	446-990-1	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/01/2015 23/01/2015	09/03/2015 09/03/2015	Details
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts	609-542-8	383178-66-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details

Showing 1,101 - 1,150 of 2,011 results.

Export in: