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Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
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There are currently no ongoing consultations.
Page 17 of 41
50 Items per Page
Showing 801 - 850 of 2,011 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (pre-natal developmental toxicity) 14/10/2011 28/11/2011 Details
chlorodimethylvinylsilane 217-007-1 1719-58-0 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethylsilanol (CAS 1066-40-6) 12/12/2014 26/01/2015 Details
Chloroethane 200-830-5 75-00-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
10/03/2017
10/03/2017
25/04/2017
25/04/2017
 Details
Choline hydroxide 204-625-1 123-41-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) 25/05/2020 09/07/2020 Details
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Citronellyl formate 203-338-9 105-85-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Cobalt 231-158-0 7440-48-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt 231-158-0 7440-48-4
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt (II) dinitrate 233-402-1 10141-05-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt (II) sulphate 233-334-2 10124-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) ; after obtaining results of the 90-day subchronic toxicity study
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
cobalt carbonate 208-169-4 513-79-1
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
cobalt di(acetate) 200-755-8 71-48-7
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
COBALT DICHLORIDE 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)

Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
 Details
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016

Details
Cobalt dichloride 231-589-4 7646-79-9
Carcinogenicity || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt dihydroxide 244-166-4 21041-93-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt dihydroxide 244-166-4 21041-93-0
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
cobalt dinitrate 233-402-1 10141-05-6
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
Cobalt hydroxide oxide 234-614-7 12016-80-7
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Cobalt sulphide (EC 215-273-3) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
 Details
Cobalt hydroxide oxide 234-614-7 12016-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt lithium dioxide 235-362-0 12190-79-3
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt oxalate 212-409-3 814-89-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt oxalate 212-409-3 814-89-1
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt oxide 215-154-6 1307-96-6
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
Cobalt oxide 215-154-6 1307-96-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
cobalt sulphate 233-334-2 10124-43-3
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
Cobalt sulphide 215-273-3 1317-42-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt sulphide 215-273-3 1317-42-6
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
 Details
Cobalt(2+) propionate 216-333-1 1560-69-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
"Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant. "
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt(II) carbonate 208-169-4 513-79-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt(II) diacetate 200-755-8 71-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt, borate 2-ethylhexanoate complexes 295-032-7 91782-60-4
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
 Details
Cobalt, borate neodecanoate complexes 270-601-2 68457-13-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt, borate neodecanoate complexes 270-601-2 68457-13-6 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) 21/01/2021 08/03/2021 Details
Cobalt, borate propionate complexes 295-033-2 91782-61-5
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane 640-964-5 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
 Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid 641-088-6 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
 Details
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine 605-296-0 162627-17-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
 Details
Condensation products of phenol and salicylaldehyde 947-320-5 - Genetic toxicity in vivo 20/05/2021 05/07/2021 Details
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
 Details
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate 600-028-9 1001254-87-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): dermal
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
Copolymer of benzenamine and formaldehyde, hydrogenated 603-894-6 135108-88-2 Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Page 17 of 41
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Showing 801 - 850 of 2,011 results.