Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1,651 - 1,700 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate	-	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: Testing proposal is based on potential concern identified by the registrant. Sub-chronic toxicity (90 day): oral	15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014	Details
Alcohols, C18-22, distn. residues	641-136-6	-	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011	29/08/2011 29/08/2011	Details
Alkane 6	438-390-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
Alkanoic acid and polyoxomolybdate borate alkanoate clusters	944-813-7	-	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	24/08/2020	08/10/2020	Details
Alkenes C20+	931-467-7	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Alkenes, C11-12	931-515-7	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	03/11/2011 03/11/2011 25/06/2012	19/12/2011 19/12/2011 09/08/2012	Details
Alkenes, C11-12, hydroformylation products, low boiling	932-235-8	-	Reproductive toxicity (two-generation reproductive toxicity)	16/06/2011	01/08/2011	Details
Alkenes, C13-14	-	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
Alkenes, C13-14	931-071-4	-	Sub-chronic toxicity (90-day): oral	25/06/2012	09/08/2012	Details
Alkenes, C13-14, hydroformylation products, low boiling	-	-	Reproductive toxicity (two-generation reproductive toxicity)	29/07/2011	12/09/2011	Details
Alkenes, C16-18	900-050-1	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011 25/06/2012	30/09/2011 30/09/2011 09/08/2012	Details
Alkenes, C20-24 alpha	700-962-8	-	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)	22/10/2013 22/10/2013	05/12/2013 05/12/2013	Details
Alkenes, C21-32 linear and branched	931-505-2	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 25/06/2012	31/10/2011 31/10/2011 09/08/2012	Details
Alkenes, C6-11 (branched), hydroformylation products, distn. residues, heavy cracked fraction	701-314-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	31/01/2023	17/03/2023	Details
Alkenes, C6-8, even and odd, linear and branched	-	-	Sub-chronic toxicity (90-day): oral	25/06/2012	09/08/2012	Details
Alkenes, C6-8, even and odd, linear and branched	-	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
alkoxy substituted aryl diazo heterocyclic aryl nitrile	-	-	Genetic toxicity in vivo	31/01/2023	17/03/2023	Details
alkyl amine and alkylbenzenesulphonate	-	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
Aluminium tris(dialkylphosphinate)	-	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	23/06/2011 23/06/2011	08/08/2011 08/08/2011	Details
Amides, C16-18 (even numbered), N-C16-18 (even numbered) alkyl	955-212-4	-	Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral	04/12/2023 04/12/2023	18/01/2024 18/01/2024	Details
Amides, C16-C18 (even numbered)	931-695-7	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Amides, C16-C18 (even) , N,N'-ethylenebis	931-299-4	-	Sub-chronic toxicity (90-day): oral	16/08/2011	30/09/2011	Details
Amides, C18 (unsaturated)	-	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Amides, C22 (unsaturated)	-	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Amides, C8-18(even-numbered) and C18(unsatd.), N-(2-hydroxypropyl)	-	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Amines, N-tallow alkyltrimethylenedi-, propoxylated	614-637-2	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
Amino functional alkoxysilanes	701-408-8	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
Amino functional alkoxysilanes	701-410-9	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane	931-219-8	-	Sub-chronic toxicity (90 day): inhalation	24/05/2013	08/07/2013	Details
Ashes (residues), nonhazardous municipal solid waste	937-417-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
Ashes (residues), nonhazardous municipal solid waste	937-417-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/08/2012 17/08/2012	01/10/2012 01/10/2012	Details
Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests)	931-257-5	-	Reproductive toxicity (pre-natal developmental toxicity)	05/04/2011	20/05/2011	Details
Benzene, diethenyl- and Benzene, ethenylethyl-	910-757-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/08/2019 16/08/2019	30/09/2019 30/09/2019	Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl	953-378-2	-	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50	701-356-6	-	Long-term toxicity to fish	22/04/2021	07/06/2021	Details
Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, magnesium salts, magnesium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50	701-469-0	-	Long-term toxicity to fish\|\|Note: testing proposed with Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 (EC no. 701-356-6)	04/09/2023	19/10/2023	Details
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1)	931-276-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE	608-613-0	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane	940-783-4	-	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched)	-	-	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	28/02/2011 28/02/2011	14/04/2011 14/04/2011	Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate	940-272-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017 01/09/2017	16/10/2017 16/10/2017 16/10/2017	Details
Boric acid (H3BO3), reaction products with ethanolamine	302-207-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
Boron trifluoride	231-569-5	-	Genetic toxicity in vivo	01/07/2011	15/08/2011	Details
Branched hexatriacontane	417-070-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
branched-nonyl 3,5,5 trimethylhexanoate	701-133-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: previous EC no 609-993-0	21/05/2018	05/07/2018	Details
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts	939-691-7	-	Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019	01/11/2019	Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate	401-100-0	-	Sub-chronic toxicity (90-day): oral	27/05/2019	11/07/2019	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance.	01/10/2018 01/10/2018 01/10/2018	15/11/2018 15/11/2018 15/11/2018	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012 25/09/2012	12/11/2012 12/11/2012	Details
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters	701-257-8	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5)	10/08/2018	24/09/2018	Details

Showing 1,651 - 1,700 of 2,011 results.

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