Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 101 - 150 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE	608-613-0	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane	940-783-4	-	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched)	-	-	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	28/02/2011 28/02/2011	14/04/2011 14/04/2011	Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate	940-272-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017 01/09/2017	16/10/2017 16/10/2017 16/10/2017	Details
Boric acid (H3BO3), reaction products with ethanolamine	302-207-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
Boron trifluoride	231-569-5	-	Genetic toxicity in vivo	01/07/2011	15/08/2011	Details
Branched hexatriacontane	417-070-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
branched-nonyl 3,5,5 trimethylhexanoate	701-133-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: previous EC no 609-993-0	21/05/2018	05/07/2018	Details
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts	939-691-7	-	Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019	01/11/2019	Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate	401-100-0	-	Sub-chronic toxicity (90-day): oral	27/05/2019	11/07/2019	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance.	01/10/2018 01/10/2018 01/10/2018	15/11/2018 15/11/2018 15/11/2018	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012 25/09/2012	12/11/2012 12/11/2012	Details
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters	701-257-8	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5)	10/08/2018	24/09/2018	Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes	700-992-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/02/2018 28/02/2018 28/02/2018	16/04/2018 16/04/2018 16/04/2018	Details
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite	947-655-7	-	Long-term toxicity to fish\|\|Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6)	15/01/2024	29/02/2024	Details
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes	700-497-0	-	Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity) Sub-chronic toxicity (90-day): oral	19/11/2010 25/06/2012	03/01/2011 09/08/2012	Details
C26-28 (even numbered) α-alkenes	934-268-3	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	18/06/2012 18/06/2012 18/06/2012	02/08/2012 02/08/2012 02/08/2012	Details
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate)	939-717-7	-	Sub-chronic toxicity (90-day): oral	02/06/2014	17/07/2014	Details
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification	932-124-4	-	Sub-chronic toxicity (90 day): inhalation	01/07/2011	15/08/2011	Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated	941-216-3	-	Bioaccumulation aquatic / sediment \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue	941-212-1	-	Bioaccumulation aquatic / sediment \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled	-	-	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane	640-964-5	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid	641-088-6	-	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011 16/08/2011	30/09/2011 30/09/2011 30/09/2011	Details
Condensation products of phenol and salicylaldehyde	947-320-5	-	Genetic toxicity in vivo	20/05/2021	05/07/2021	Details
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride	-	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/03/2017 10/03/2017 10/03/2017	25/04/2017 25/04/2017 25/04/2017	Details
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts	-	-	7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474	03/12/2010	17/01/2011	Details
Cyclohexyldimethoxymethylsilane	402-140-1	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol	446-990-1	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/01/2015 23/01/2015	09/03/2015 09/03/2015	Details
Decene, hydroformylation products, high boiling	935-454-7	-	Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Destillation fraction of chlorosilanes	700-717-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/05/2012 16/05/2012	02/07/2012 02/07/2012	Details
Dicyclopentyldimethoxysilane	404-370-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/12/2011 16/12/2011 16/12/2011	30/01/2012 30/01/2012 30/01/2012	Details
Disodium hydroxy-substituted alkanoate	-	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
Distilled tall oil, magnesium salts	939-629-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Essential oil of Spearmint obtained from the aerial part of Mentha spicata and/or Mentha cardiaca (Lamiaceae) obtained by distillation	946-253-9	-	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide	919-846-5	-	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with an analogous substance Sub-chronic toxicity (90-day): oral	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol	952-795-7	-	Long-term toxicity to fish	03/11/2023	18/12/2023	Details
Ethoxypropyl-hydroxy-hexanamide	-	-	Reproductive/developmental toxicity	04/12/2009	18/01/2010	Details
ethyl methyl carbonate	433-480-9	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance.	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Everzol Red CDN Crude	483-940-8	-	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	31/01/2018	19/03/2018	Details
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products	800-253-4	-	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Link to registration dossier not given as the dossier not yet disseminated.	30/11/2015	14/01/2016	Details
Fatty acid chlorides, C18 unsatd., reaction products with sodium N-methyltaurinate	939-538-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014	19/05/2014 19/05/2014	Details
Fatty acids C18 unsat, reaction products with Pentaethylenehexamine	629-732-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids C18 unsat, reaction products with polyethylene amines	629-742-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids, C12-14, α-sulfo, disodium salts	942-523-5	-	Long-term toxicity to fish (OECD 212 – Registrant’s preference) Reproductive toxicity (pre-natal developmental toxicity) on rodents Sub-chronic toxicity (90-day): oral on rodents	25/06/2019 25/06/2019 25/06/2019	09/08/2019 09/08/2019 09/08/2019	Details
Fatty acids, C12-14, α-sulfo, disodium salts	942-523-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/11/2018 02/11/2018	17/12/2018 17/12/2018	Details
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts	947-394-9	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	19/10/2020 19/10/2020 19/10/2020	03/12/2020 03/12/2020 03/12/2020	Details
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol	948-052-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/01/2021	08/03/2021	Details
Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized	931-203-0	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/03/2011 15/03/2011	29/04/2011 29/04/2011	Details
Fatty acids, C16-18 (even numbered), reaction products with triethanolamine, di-Me sulfate-quaternized	931-209-3	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/03/2011 15/03/2011	29/04/2011 29/04/2011	Details

Showing 101 - 150 of 2,011 results.

Export in: