Prethodne/rezultati
Prethodne/rezultati
Prethodne/rezultati
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene | 807-113-1 | 3709-71-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
Octa-1,7-diene | 223-054-9 | 3710-30-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
2,4-Pentanedione, peroxide | 253-384-9 | 37187-22-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol | 500-099-5 | 37625-56-2 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2011 | 29/08/2011 | Details | |
2-phosphonobutane-1,2,4-tricarboxylic acid | 253-733-5 | 37971-36-1 |
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride | 253-781-7 | 38103-06-9 | Sub-chronic toxicity (90-day): oral | 27/01/2020 | 12/03/2020 | Details | |
2-Propyn-1-ol, compd. with methyloxirane | 609-530-2 | 38172-91-7 | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine | 500-101-4 | 38294-64-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts | 609-542-8 | 383178-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
bis(3,5,5-trimethylhexanoyl) peroxide | 223-356-0 | 3851-87-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate | 253-981-4 | 38517-37-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) || Note: Testing proposal is based on concern identified by the registrant. | 17/12/2019 | 31/01/2020 | Details | |
1,1'-(p-tolylimino)dipropan-2-ol | 254-075-1 | 38668-48-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/03/2016 17/04/2015 |
28/04/2016 04/06/2015 |
Details | |
[hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt | 254-135-7 | 38820-59-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
(phenylethyl)benzene | 254-179-7 | 38888-98-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
2,6,10-trimethyldodecane | 622-542-2 | 3891-98-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
Bumetrizole | 223-445-4 | 3896-11-5 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
Sodium chloroacetate | 223-498-3 | 3926-62-3 | Reproductive toxicity (two-generation reproductive toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Sodium chloroacetate | 223-498-3 | 3926-62-3 | Reproductive toxicity (pre-natal developmental toxicity) | 14/10/2011 | 28/11/2011 | Details | |
Phosphoric acid, dodecyl ester, potassium salt | 254-414-3 | 39322-78-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
Nonane-1,9-diol | 223-517-5 | 3937-56-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Phosphoric acid, octadecyl ester | 254-466-7 | 39471-52-8 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 04/06/2015 |
Details | |
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate | 254-588-0 | 39670-09-2 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-107-7 | 40039-93-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
2,3-epoxypropyl isopropyl ether | 223-672-9 | 4016-14-2 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
(2,4,6-trioxo-1,3,5-triazine-1,3,5(2H,4H,6H)-triyl)tri-2,1-ethanediyl triacrylate | 254-843-6 | 40220-08-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
2-(2-thienyl)ethyl toluene-p-sulphonate | 254-911-5 | 40412-06-4 | Genetic toxicity in vivo | 06/09/2018 | 22/10/2018 | Details | |
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate | 254-959-7 | 40530-60-7 | Genetic toxicity in vivo || Note: testing proposed with Disperse Red 302:1 (EC 248-882-8) | 23/11/2020 | 07/01/2021 | Details | |
1,3,5-tris[[4-tert-butyl-3-hydroxy-2,6-xylyl]methyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 254-996-9 | 40601-76-1 | Reproductive toxicity (pre-natal developmental toxicity) with Rat | 24/07/2019 | 09/09/2019 | Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 |
Details | |
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide | 223-829-1 | 4090-51-1 | Sub-chronic toxicity (90-day): oral | 16/06/2022 | 01/08/2022 | Details | |
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate | 255-180-5 | 41026-17-9 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate | 255-180-5 | 41026-17-9 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2016 16/12/2016 16/12/2016 |
30/01/2017 30/01/2017 30/01/2017 |
Details | |
Tris(p-isocyanatophenyl) thiophosphate | 223-981-9 | 4151-51-3 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate | 223-989-2 | 4156-21-2 | Sub-chronic toxicity (90-day): oral | 29/04/2014 | 13/06/2014 | Details | |
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate | 223-989-2 | 4156-21-2 | Reproductive toxicity (pre-natal developmental toxicity) | 03/04/2023 | 22/05/2023 | Details | |
1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone | 255-460-7 | 41611-76-1 | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
2,2-dimethylpropane-1,3-diyl dibenzoate | 224-081-9 | 4196-89-8 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate | 224-116-8 | 4203-89-8 | Genetic toxicity in vivo | 23/03/2020 | 07/05/2020 | Details | |
Isononyl isononanoate | 609-993-0 | 42131-25-9 | Sub-chronic toxicity (90-day): oral | 18/09/2014 | 03/11/2014 | Details | |
3,3'-oxybis(ethyleneoxy)bis(propylamine) | 224-207-2 | 4246-51-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) | 16/03/2015 | 30/04/2015 | Details | |
methylsilanetriyl triacetate | 224-221-9 | 4253-34-3 | Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) | 03/10/2023 | 17/11/2023 | Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/03/2023 01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 17/04/2023 |
Details | |
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate | 255-901-3 | 42594-17-2 |
Bioaccumulation test (Bioconcentration: Flow-through Fish Test) Reproductive toxicity (pre-natal developmental toxicity) |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate | 255-901-3 | 42594-17-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |