Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| 4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid | 929-209-3 | - | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
| 4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
| 4,4'-Isopropylidenediphenol, ethoxylated | 500-082-2 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/05/2018 21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 05/07/2018 |
Details | |
| 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol | 701-072-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
| 5-Methoxy-2-tetralone | 457-080-9 | - | Genetic toxicity in vivo | 06/09/2018 | 22/10/2018 | Details | |
| 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt | 429-070-4 | - | Sub-chronic toxicity (90-day): oral | 22/04/2021 | 07/06/2021 | Details | |
| A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. | 943-834-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
| A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate | 413-750-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
| A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate | 410-800-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 |
Details | |
| A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) | 400-830-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2011 | 30/01/2012 | Details | |
| Acetalization products between glucose and C16-18(even numbered)- alcohol | 927-870-2 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
| Acetalization products between glucose and C20-22(even numbered)- alcohol | 923-835-0 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
| Activated Carbon - High Density Skeleton | 931-328-0 | - | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
| Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant. Sub-chronic toxicity (90 day): oral |
15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 |
Details | |
| Alcohols, C18-22, distn. residues | 641-136-6 | - |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
| Alkane 6 | 438-390-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
| Alkanoic acid and polyoxomolybdate borate alkanoate clusters | 944-813-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
| Alkenes C20+ | 931-467-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
| Alkenes, C11-12 | 931-515-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/11/2011 03/11/2011 25/06/2012 |
19/12/2011 19/12/2011 09/08/2012 |
Details | |
| Alkenes, C11-12, hydroformylation products, low boiling | 932-235-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 16/06/2011 | 01/08/2011 | Details | |
| Alkenes, C13-14 | 931-071-4 | - | Sub-chronic toxicity (90-day): oral | 25/06/2012 | 09/08/2012 | Details | |
| Alkenes, C13-14 | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| Alkenes, C13-14, hydroformylation products, low boiling | - | - | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
| Alkenes, C16-18 | 900-050-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 25/06/2012 |
30/09/2011 30/09/2011 09/08/2012 |
Details | |
| Alkenes, C20-24 alpha | 700-962-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0) |
22/10/2013 22/10/2013 |
05/12/2013 05/12/2013 |
Details | |
| Alkenes, C21-32 linear and branched | 931-505-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 25/06/2012 |
31/10/2011 31/10/2011 09/08/2012 |
Details | |
| Alkenes, C6-11 (branched), hydroformylation products, distn. residues, heavy cracked fraction | 701-314-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| Alkenes, C6-8, even and odd, linear and branched | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
| Alkenes, C6-8, even and odd, linear and branched | - | - | Sub-chronic toxicity (90-day): oral | 25/06/2012 | 09/08/2012 | Details | |
| alkoxy substituted aryl diazo heterocyclic aryl nitrile | - | - | Genetic toxicity in vivo | 31/01/2023 | 17/03/2023 | Details | |
| alkyl amine and alkylbenzenesulphonate | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 |
Details | |
| Aluminium tris(dialkylphosphinate) | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
23/06/2011 23/06/2011 |
08/08/2011 08/08/2011 |
Details | |
| Amides, C16-18 (even numbered), N-C16-18 (even numbered) alkyl | 955-212-4 | - |
Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral |
04/12/2023 04/12/2023 |
18/01/2024 18/01/2024 |
Details | |
| Amides, C16-C18 (even numbered) | 931-695-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Amides, C16-C18 (even) , N,N'-ethylenebis | 931-299-4 | - | Sub-chronic toxicity (90-day): oral | 16/08/2011 | 30/09/2011 | Details | |
| Amides, C18 (unsaturated) | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Amides, C22 (unsaturated) | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Amides, C8-18(even-numbered) and C18(unsatd.), N-(2-hydroxypropyl) | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Amines, N-tallow alkyltrimethylenedi-, propoxylated | 614-637-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| Amino functional alkoxysilanes | 701-410-9 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
| Amino functional alkoxysilanes | 701-408-8 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
| Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane | 931-219-8 | - | Sub-chronic toxicity (90 day): inhalation | 24/05/2013 | 08/07/2013 | Details | |
| Ashes (residues), nonhazardous municipal solid waste | 937-417-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
| Ashes (residues), nonhazardous municipal solid waste | 937-417-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/08/2012 17/08/2012 |
01/10/2012 01/10/2012 |
Details | |
| Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests) | 931-257-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 05/04/2011 | 20/05/2011 | Details | |
| Benzene, diethenyl- and Benzene, ethenylethyl- | 910-757-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/08/2019 16/08/2019 |
30/09/2019 30/09/2019 |
Details | |
| benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl | 953-378-2 | - | Long-term toxicity to fish | 30/09/2021 | 15/11/2021 | Details | |
| benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50 | 701-356-6 | - | Long-term toxicity to fish | 22/04/2021 | 07/06/2021 | Details | |
| Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, magnesium salts, magnesium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 | 701-469-0 | - | Long-term toxicity to fish||Note: testing proposed with Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 (EC no. 701-356-6) | 04/09/2023 | 19/10/2023 | Details | |
| Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) | 931-276-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |