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Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
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There are currently no ongoing consultations.
Page 17 of 41
50 Items per Page
Showing 801 - 850 of 2,011 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
bismuth oxide salicylate 238-953-1 14882-18-9 Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) 18/09/2014 03/11/2014 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
Dichloro(methyl)(phenyl)silane 205-746-2 149-74-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) 04/04/2014 19/05/2014 Details
Mequinol 205-769-8 150-76-5 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2011 14/06/2011 Details
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2017
17/05/2017
03/07/2017
03/07/2017
 Details
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011 Details
1-Dodecene, dimer with 1-decene, hydrogenated 604-766-2 151006-58-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
01/07/2021
01/07/2021
01/07/2021
16/08/2021
16/08/2021
16/08/2021
 Details
A mixture of isomers of branched tetracosane 417-060-2 151006-61-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
01/07/2021
01/07/2021
01/07/2021
16/08/2021
16/08/2021
16/08/2021
 Details
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane 429-280-6 151900-44-6 Reproductive toxicity (developmental toxicity) 01/09/2010 15/10/2010 Details
Methyl benzoylformate 239-263-3 15206-55-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
12/12/2022
12/12/2022
 Details
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017 Details
(chloromethyl)triethoxysilane 239-311-3 15267-95-5 Genetic toxicity in vivo 16/10/2014 01/12/2014 Details
Copper(I, II) sulfite 884-197-6 15293-86-4 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) 08/03/2024 22/04/2024 Details
3-(trimethoxysilyl)propyl isocyanate 239-415-9 15396-00-6
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
 Details
2,2'-(octylimino)bisethanol 239-555-0 15520-05-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/11/2019
25/11/2019
09/01/2020
09/01/2020
 Details
bis(4-tert-butylcyclohexyl) peroxydicarbonate 239-557-1 15520-11-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
 Details
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine 239-590-1 15541-60-3 Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-8 15545-97-8 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
calcium cyanamide 205-861-8 156-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
Cobalt(2+) propionate 216-333-1 1560-69-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/10/2022 12/12/2022 Details
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane 216-365-6 1565-76-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
 Details
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine 239-816-9 15721-78-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
 Details
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate 605-104-5 157577-99-6 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts 500-345-1 157627-95-7 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2023 14/08/2023 Details
sodium cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2016 30/01/2017 Details
Sodium p-cumenesulphonate 239-854-6 15763-76-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate
22/06/2017
22/06/2017
07/08/2017
07/08/2017
 Details
sodium p-cumenesulphonate 239-854-6 15763-76-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate 24/04/2015 12/06/2015 Details
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
 Details
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
 Details
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized 605-143-8 158318-67-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014 Details
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate 239-937-7 15834-04-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine 500-425-6 159034-91-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/08/2021
26/08/2021
11/10/2021
11/10/2021
 Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine 500-425-6 159034-91-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021 Details
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate 403-500-0 159120-95-3 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
Triammonium hydrogen ethylenediaminetetraacetate 240-073-8 15934-01-7 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone 216-475-4 1594-08-7 Genetic toxicity in vivo 01/07/2021 16/08/2021 Details
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
 Details
Fatty acids, tall oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts, consisting of mainly calcium, magnesium, zinc salts of maleated rosin, fatty acids and rosin 500-451-8 160901-14-4
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Fatty acids, tall-oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts 500-451-8 160901-14-4 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
 Details
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated 500-537-5 161075-00-9 Bioaccumulation aquatic / sediment 16/10/2014 01/12/2014 Details
Bis(2-ethylhexyl) peroxydicarbonate 240-282-4 16111-62-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
 Details
2,2-dimethyl-3-oxopropyl acetate 811-188-6 16184-79-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 01/09/2017 16/10/2017 Details
Tris(2,5,8,11-tetraoxatridecyl) orthoborate 310-290-3 161907-80-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
Page 17 of 41
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