Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| Diethylamine | 203-716-3 | 109-89-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dimethylamine (CAS 124-40-3) | 21/09/2020 | 05/11/2020 | Details | |
| 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 2,4'-diisocyanatodiphenylmethane | 500-297-1 | 109331-54-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 31/01/2023 | 17/03/2023 | Details | |
| Di-tert-butyl peroxide | 203-733-6 | 110-05-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
| 5-methylhexan-2-one | 203-737-8 | 110-12-3 | Reproductive toxicity (pre-natal developmental toxicity) | 14/02/2011 | 31/03/2011 | Details | |
| Maleic acid | 203-742-5 | 110-16-7 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2020 | 03/08/2020 | Details | |
| Heptan-2-one | 203-767-1 | 110-43-0 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
| Butane-1,4-diol | 203-786-5 | 110-63-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/04/2021 | 07/06/2021 | Details | |
| 2-ethylaminoethanol | 203-797-5 | 110-73-6 | Sub-chronic toxicity (90-day): oral | 18/02/2014 | 04/04/2014 | Details | |
| Zinc bis[bis(tetrapropylenephenyl)] bis(hydrogen dithiophosphate) | 234-277-6 | 11059-65-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer | 234-293-3 | 11071-15-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
| 2,6,10,15,19,23-hexamethyltetracosane | 203-825-6 | 111-01-3 | Bioaccumulation aquatic / sediment | 14/08/2014 | 28/09/2014 | Details | |
| N-(2-hydroxypropyl)oleamide | 203-828-2 | 111-05-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
| Heptanoic acid | 203-838-7 | 111-14-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 |
Details | |
| Heptanoic acid | 203-838-7 | 111-14-8 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
| Heptanoic acid | 203-838-7 | 111-14-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 24/07/2019 | 09/09/2019 | Details | |
| N,N,N',N'-tetramethylhexamethylenediamine | 203-842-9 | 111-18-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
| 2,2'-iminodi(ethylamine) | 203-865-4 | 111-40-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
| 2,2`-iminodi(ethylamine),N-(2-aminoethyl)ethane-1,2-diamine | 203-865-4 | 111-40-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
05/04/2011 05/04/2011 05/04/2011 |
20/05/2011 20/05/2011 20/05/2011 |
Details | |
| Oct-1-ene | 203-893-7 | 111-66-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| Heptan-1-ol | 203-897-9 | 111-70-6 |
Long-term toxicity to fish Long-term toxicity to fish Sub-chronic toxicity (90 day): Oral |
04/09/2012 18/02/2014 04/09/2012 |
19/10/2012 04/04/2014 19/10/2012 |
Details | |
| Heptanal | 203-898-4 | 111-71-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Heptanoic acid (CAS No. 111-14-8) |
25/11/2019 | 09/01/2020 | Details | |
| Heptanal | 203-898-4 | 111-71-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
| 2-(2-methoxyethoxy)ethanol | 203-906-6 | 111-77-3 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2019 | 05/12/2019 | Details | |
| Bis(2-chloroethoxy)methane | 203-920-2 | 111-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 |
Details | |
| dimethoxydimethylsilane | 214-189-4 | 1112-39-6 | Sub-chronic toxicity (90 day): inhalation | 16/10/2014 | 01/12/2014 | Details | |
| dimethoxydimethylsilane | 214-189-4 | 1112-39-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| 2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
| 2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 | Sub-chronic toxicity (90-day): oral | 18/02/2021 | 05/04/2021 | Details | |
| 3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropionate | 214-222-2 | 1115-20-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 15/07/2011 |
Details | |
| n-butyltin trichloride | 214-263-6 | 1118-46-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
| Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/06/2018 | 02/08/2018 | Details | |
| Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Long-term toxicity to fish | 01/04/2022 | 16/05/2022 | Details | |
| Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Sub-chronic toxicity (90-day): oral | 18/09/2014 | 03/11/2014 | Details | |
| Decanal | 203-957-4 | 112-31-2 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
| 2-(2-(2-methoxyethoxy)ethoxy)ethanol | 203-962-1 | 112-35-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
| undec-10-enoic acid | 203-965-8 | 112-38-9 | Long-term toxicity to fish | 16/10/2014 | 01/12/2014 | Details | |
| undec-10-enoic acid | 203-965-8 | 112-38-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
20/05/2021 20/05/2021 |
05/07/2021 05/07/2021 |
Details | |
| Dodecane | 203-967-9 | 112-40-3 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
| Dodec-1-ene | 203-968-4 | 112-41-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| 2-(2-(2-ethoxyethoxy)ethoxy)ethanol | 203-978-9 | 112-50-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
| Tridecan-1-ol | 203-998-8 | 112-70-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 10/05/2022 | 27/06/2022 | Details | |
| Octadec-1-ene | 204-012-9 | 112-88-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| Icosane | 204-018-1 | 112-95-8 | Reproductive toxicity (two-generation reproductive toxicity)// Note: Testing proposed with Hydrocarbon, C9-C12, normal, isoalkane, cyclics, 2-25% aromatics; Hydrocarbon, C16-C20, normal, isoalkane cyclics, 2-30% aromatics | 02/07/2013 | 16/08/2013 | Details | |
| Undecane | 214-300-6 | 1120-21-4 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
| Tetradec-1-ene | 214-306-9 | 1120-36-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| N-butyl phenyl ether | 214-426-1 | 1126-79-0 | Long-term toxicity to fish | 03/04/2023 | 22/05/2023 | Details | |
| 4-hydroxybenzophenone | 214-507-1 | 1137-42-4 | Genetic toxicity in vivo | 18/02/2021 | 05/04/2021 | Details | |
| Phenol, 4,4'-(1-methylethylidene)bis-, oligomeric reaction products with 2-(chloromethyl)oxirane, reaction products with 1,3-benzenedimethanamine | 500-302-7 | 113930-69-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
| 2'-phenylacetohydrazide | 204-055-3 | 114-83-0 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
| Naphthalene-2,6-dicarboxylic acid | 214-527-0 | 1141-38-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2022 | 01/08/2022 | Details | |