Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
inorganic phosphorus salt | 428-310-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
isliFe | - | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 17/12/2019 | 31/01/2020 | Details | |
Itaconic acid | 202-599-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 16/01/2012 | 01/03/2012 | Details | |
LiFePO4 | 476-700-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 22/10/2013 | 05/12/2013 | Details | |
Lithium bis(oxalato)borate | 456-990-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs | 931-371-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Methylene-bis-4,1-(N-phenylene-N'-butylurea) | 416-600-4 | - | Bioaccumulation aquatic / sediment | 17/05/2016 | 01/07/2016 | Details | |
Middle distillate from refinery proces cofeeding vegetable oil | 938-793-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2013 | 18/10/2013 | Details | |
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol | 700-427-9 | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
01/12/2010 01/12/2010 01/12/2010 |
17/01/2011 17/01/2011 17/01/2011 |
Details | |
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide | 419-710-0 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
12/12/2014 12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 26/01/2015 |
Details | |
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) | 939-700-4 | - | Sub-chronic toxicity (90-day): oral | 21/10/2019 | 05/12/2019 | Details | |
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
N-(2-nitrophenyl)phosphoric triamide | 477-690-9 | - | Long-term toxicity to fish | 18/03/2021 | 03/05/2021 | Details | |
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine | 628-863-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
N-(C16-C18)alkyl(C16-C18)alkane-1-amine | 629-721-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 |
Details | |
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide | 700-208-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2018 | 19/11/2018 | Details | |
N-[2-(piperazin-1-yl)ethyl]C18-unsatured-alkylamide | 629-767-5 | - |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 29/08/2011 |
Details | |
N-benzyl-N-C16-18 (even numbered)-alkyl-N-methyl-C16-18 (even numbered)-alkyl-1-aminium chloride | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine | 701-177-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2021 | 07/12/2021 | Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine | 701-437-6 | - | Sub-chronic toxicity (90-day): oral|| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2) | 15/07/2022 | 29/08/2022 | Details | |
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine | 939-379-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Nonanoic acid (branched), 2-oxiranylmethyl ester | 940-029-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) |
20/09/2013 20/09/2013 20/09/2013 |
04/11/2013 04/11/2013 04/11/2013 |
Details | |
O,O-di(1-methylethyl)trithio-bis-thioformate,O,O-di(1-methylethyl)tetrathio-bis-thioformate,O,O-di(1-methylethyl)pentathio-bis-thioformate | 403-030-6 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine | 907-495-0 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
Octadecanoic acid, sulfonated, potassium salt | 701-179-4 | - | Sub-chronic toxicity (90-day): oral || Note: The List number has changed. | 31/01/2018 | 19/03/2018 | Details | |
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate | 928-226-3 | - | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Pentaerythritol, reaction product with fatty acids, C8 to 18 (even numbered) and/or branched and/or unsaturated | 484-420-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/04/2012 | 14/06/2012 | Details | |
pentasodium 4-amino-3-[{4-[(2,4-disulfonatophenyl)diazenyl]-3-methylphenyl}diazenyl]-5-hydroxy-6-[(4-nitro-2-sulfonatophenyl)diazenyl]naphthalene-1,7-disulfonate | 948-569-2 | - | Genetic toxicity in vivo | 01/04/2022 | 16/05/2022 | Details | |
Pentyl 2-cyano-(3-(6-methoxybenzothiazol-2-ylimino)-2,3-dihydro-1H-isoindol-1-ylidene)acetate | 436-060-3 | - | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics | 941-803-4 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
||Note: testing proposed with Fuels, diesel (EC no. 269-822-7)
||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5)
||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
Phosphoric acid, C11-14 (C13-rich)-isoalkyl mono- and di-esters, partially salted with 1-Propanamine, 3-(tridecyloxy)-, branched | 947-480-6 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
plastic, waste, pyrolized, fractionation bottoms (raw diesel) | 942-177-5 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
Platinum(IV) aqua hydroxo nitrato complexes | 701-319-4 | - | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
platinum(IV) nitrate/nitric acid solution | 432-400-1 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
Platinum, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane complexes | 701-315-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
Polar modified Rice Bran Wax | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 03/05/2023 | 19/06/2023 | Details | |
Poly(alkan-2-yl)heteropolycycle | - | - | Genetic toxicity in vivo | 31/01/2013 | 18/03/2013 | Details | |
Poly-(1,4-diisopropylbenzol) | 449-400-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Poly[oxy(methyl-1,2-ethanediyl)], .alapha.,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-[(1-oxo-2-propenyl)oxy | 701-440-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
Polyamide wax | 434-430-9 | - | Long-term toxicity to fish | 07/07/2020 | 21/08/2020 | Details | |
Polysulfides, bis[3-(triethoxysilyl)propyl] | 915-673-4 | - | Sub-chronic toxicity (90-day): oral | 21/10/2021 | 07/12/2021 | Details | |
Polysulfides, bis[3-(triethoxysilyl)propyl] | 915-673-4 | - | Reproductive/developmental toxicity | 22/12/2010 | 07/02/2011 | Details | |
Polysulfides, bis[3-(triethoxysilyl)propyl] | 915-673-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
Polysulfides, bis[3-(triethoxysilyl)propyl] | 915-673-4 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 |
Details | |
Polysulfo {5-hydroxy-1-naphthalen-2-yl-[4-[4-(2-sulfatoethyl-sulfonyl)-phenyl]diazenyl]-1H-pyrazole-3-carboxylic acid}, alkali metal salt | - | - | Genetic toxicity in vivo | 09/11/2009 | 24/12/2009 | Details | |
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1) | 701-184-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Product of Semi-Dry Absorption method of Flue Gas Desulphurization (SDA Product) | 931-259-6 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 |
Details | |
Propionaldehyde, reaction product with formaldehyde | 701-281-9 | - | Genetic toxicity in vivo || Note: the EC/list number of the substance has been changed. | 10/12/2018 | 24/01/2019 | Details | |
Propylidynetrimethanol, propoxylated | 500-041-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride | 700-961-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Reaction mass of (4R)-isopropenyl-1-methylcyclohexene and (4S)-isopropenyl-1-methylcyclohexene and 1-isopropyl-4-methylcyclohexa-1,3-diene and 1-isopropyl-4-methylcyclohexa-1,4-diene and 4-isopropylidene-1-methylcyclohexene | 905-474-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- | 911-819-6 | - | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
Reaction mass of 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched and 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched acetate | 931-295-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol | 911-819-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
16/08/2019 16/08/2019 |
30/09/2019 30/09/2019 |
Details | |
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol | 911-819-6 | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 |
Details | |
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane | 608-489-8 | - | Genetic toxicity in vivo | 03/02/2016 | 21/03/2016 | Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Sub-chronic toxicity (90-day): oral | 10/05/2022 | 27/06/2022 | Details | |
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine | 447-920-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/05/2018 | 05/07/2018 | Details | |
Reaction mass of 1-chlorobut-2-ene and 3-chlorobut-1-ene | 908-820-9 | - | Genetic toxicity in vivo | 16/07/2012 | 30/08/2012 | Details | |
Reaction mass of 1-methyl-4-(1-methylethylidene)cyclohexyl acetate and p-menth-1-en-8-yl acetate | 904-693-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 04/09/2023 | 19/10/2023 | Details | |
Reaction mass of 1-phenyloctadecane-1,3-dione and phenylicosane-1,3-dione | 915-316-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
Reaction mass of 2,2',2''-nitrilotriethanol and disodium succinate and sodium acetate and sodium bromide | 905-908-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- | 911-490-9 | - | Sub-chronic toxicity (90-day): oral | 27/05/2019 | 11/07/2019 | Details | |
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- | 911-490-9 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
18/11/2014 18/11/2014 |
02/01/2015 02/01/2015 |
Details | |
Reaction mass of 2,2'-oxydibutane and 2-methylpropan-2-ol and butan-2-ol and 2,2'-oxydipropane | 903-919-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
29/07/2011 29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 12/09/2011 |
Details | |
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) | 941-357-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 911-381-6 | - | Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
Reaction mass of 2,5,8,11-tetraoxatridecan-13-ol and 2,5,8,11,14-pentaoxahexadecan-16-ol | 915-389-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC no. 203-962-1) | 01/04/2022 | 16/05/2022 | Details | |
Reaction mass of 2,5-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane and 2,6-bis(isocyanatomethyl)-bicyclo[2.2.1]heptane | 411-280-2 | - | Genetic toxicity in vivo | 16/07/2012 | 30/08/2012 | Details | |
Reaction mass of 2,6-Octadien-1-ol, 3,7-dimethyl-, (E) and 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)- | 906-125-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 |
Details | |
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) | 916-899-6 | - | Sub-chronic toxicity (90-day): oral | 10/08/2018 | 24/09/2018 | Details | |
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone | 915-623-1 | - |
Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone | 915-623-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone | 915-623-1 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 10/08/2018 | 24/09/2018 | Details | |
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 27/05/2019 | 11/07/2019 | Details | |
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol | 907-996-4 | - | Reproductive toxicity (pre-natal developmental toxicity) 1st and 2nd PNDTs: || Note: testing proposed with 2-92-92-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) | 27/01/2020 | 12/03/2020 | Details | |
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid | 940-877-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/03/2019 29/03/2019 |
13/05/2019 13/05/2019 |
Details | |
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol | 941-357-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
08/02/2017 08/02/2017 |
27/03/2017 27/03/2017 |
Details | |
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2018 06/09/2018 |
22/10/2018 22/10/2018 |
Details | |
Reaction mass of 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol and propylidynetrimethanol | 904-153-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Reaction mass of 2-methylpent-2-ene and diisopropyl ether | 906-484-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
29/07/2011 29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 12/09/2011 |
Details | |
Reaction mass of 2-tert-butyl-4,6-dimethylphenol and 4-tert-butyl-2,5-dimethylphenol | 911-254-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Reaction mass of 3,5,6,6-tetramethyl-4-methyleneheptan-2-one and (E)-3,4,5,6,6-pentamethylhept-3-en-2-one | 946-245-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/06/2023 | 21/07/2023 | Details | |
Reaction mass of 3-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde and 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde | 915-650-9 | - |
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8) Sub-chronic toxicity (90-day): oral||Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8) |
04/09/2023 04/09/2023 |
19/10/2023 19/10/2023 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - | Sub-chronic toxicity (90-day): oral | 21/12/2021 | 04/02/2022 | Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl | 905-837-3 | - | Long-term toxicity to fish || Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4) | 26/08/2021 | 11/10/2021 | Details | |
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate | 905-806-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6) Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6) |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) | 25/05/2020 | 09/07/2020 | Details | |
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol | 939-071-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
Reaction mass of 4-tert-butylphenyl diphenyl phosphate and bis(4-tert-butylphenyl) phenyl phosphate and triphenyl phosphate | 700-990-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt | 445-040-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate | 946-378-9 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- | 911-811-2 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt | 939-513-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated | 932-164-2 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs. | 915-790-0 | - | Sub-chronic toxicity (90-day): oral | 12/12/2014 | 26/01/2015 | Details | |
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form | 939-559-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
Reaction mass of Benzeneacetic acid, alpha-oxo-, 1,1'-(oxydi-2,1-ethanediyl) ester and Benzeneacetic acid, alpha-oxo-, 2-(2-hydroxyethoxy)ethyl ester | 442-300-8 | - | Sub-chronic toxicity (90-day): oral | 04/10/2013 | 18/11/2013 | Details | |
Reaction Mass of Benzyl (1R,1S) 2,2,4-trimethyl-1-[(2-methylpropanoyl)oxy]pentan-3-yl benzene-1,2-dicarboxylate and Benzyl (3R,3S) 2,2,4-trimethyl-3-[(2-methylpropanoyl)oxy]pentyl benzene-1,2-dicarboxylate | 701-008-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate | 905-983-8 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Reaction mass of Bis(1,2,2,6,6-pentamethyl-4-piperidyl) sebacate and Methyl 1,2,2,6,6-pentamethyl-4-piperidyl sebacate | 915-687-0 | - | Genetic toxicity in vivo | 15/09/2011 | 31/10/2011 | Details | |
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane | 406-750-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
04/06/2012 04/06/2012 |
19/07/2012 19/07/2012 |
Details | |
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate | 940-592-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate | 931-536-1 | - | Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) | 943-172-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/05/2016 17/05/2016 17/05/2016 |
01/07/2016 01/07/2016 01/07/2016 |
Details | |
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol | 939-719-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction mass of cobalt and copper and iron | 912-664-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Reaction mass of cobalt sulphide and nickel sulphide and trinickel disulphide | 910-663-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Reaction mass of dibutyl adipate and dibutyl glutarate | 936-196-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate | 907-870-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) ||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate | 911-351-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate | 950-225-1 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) |
17/12/2019 17/12/2019 |
31/01/2020 31/01/2020 |
Details | |
Reaction mass of dipotassium 3,3'-sulphonylbis(benzenesulphonate) and potassium 3-(phenylsulphonyl)benzenesulphonate | 915-932-1 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride | 947-115-0 | - | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Reaction mass of Disodium dihydroxy[3-(hydroxy-kO)-4-{[5-(hydroxy-kO)-3-methyl-1-phenyl-1Hpyrazol-4-yl]diazenyl-kN1}naphthalene-1-sulfonato(3-)]chromate(2-) and sodium [4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxynaphthalene-1-sulphonato(3-)]hydroxychromate(1-) | 944-272-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate | - | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity study (90-day): oral |
13/12/2010 13/12/2010 |
27/01/2011 27/01/2011 |
Details | |
Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride | 951-974-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) | 23/11/2020 | 07/01/2021 | Details | |
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - | Long-term toxicity to fish | 25/11/2019 | 09/01/2020 | Details | |
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
Reaction mass of hydrogenated and dehydrogenated rosin | 911-238-8 | - |
Reproductive toxicity (pre-natal developmental toxicity)|| Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Reproductive toxicity (two-generation reproductive toxicity) || Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate | 908-996-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). Sub-chronic toxicity (90-day): oral || Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
Reaction mass of N,N,N',N'-tetrabutylmethylenediamine and dibutylamine | 948-040-6 | - | Genetic toxicity in vivo || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: Testing proposal is based on concern identified by the registrant. | 24/01/2019 | 11/03/2019 | Details | |
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid | 934-058-1 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide | 943-947-3 | - | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- | 907-495-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit Sub-chronic toxicity (90 day): inhalation |
27/05/2019 27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 11/07/2019 |
Details | |
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene | 931-893-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Reaction mass of Poly(oxy-1,2-ethanediyl), ?-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-?-hydroxy-, mono-C13-15-alkyl ethers (odd numbered, branched and linear)-alkylethers, Acetamide, 2-(C13-15 (odd numbered, branched and linear)-alkyloxy)-N-(2-hydroxyethyl)- and Alcohols, C13-15-branched and linear | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/08/2011 | 30/09/2011 | Details | |
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate | 939-595-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol | 904-153-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-657-7 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-568-3 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/08/2013 |
Details | |
Reaction mass of Rosin, hydrogenated and [1R-(1a,4ß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid | 911-238-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate | 911-616-2 | - | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid | 939-201-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
Reaction mass of Sodiumbis[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodium [1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)][1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodiumbis[1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) | 915-756-5 | - | Genetic toxicity in vivo | 21/12/2021 | 04/02/2022 | Details | |
Reaction mass of trientine and trientine, mono- and di-propoxylated | 942-835-1 | - | Genetic toxicity in vivo||Note: testing proposed with [Amines, polyethylenepoly-, triethylenetetramine fraction] (EC no. 292-588-2) | 03/10/2023 | 17/11/2023 | Details | |
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) | 945-577-8 | - | Sub-chronic toxicity (90-day): oral | 01/07/2021 | 16/08/2021 | Details | |
reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate | 442-300-8 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/01/2013 | 01/03/2013 | Details | |
Reaction product Formaldehyde, amine and phenol | 476-290-1 | - | Genetic toxicity in vivo | 15/08/2013 | 30/09/2013 | Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) | 926-119-6 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) | 30/09/2021 | 15/11/2021 | Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine | 924-670-7 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) | 16/06/2022 | 01/08/2022 | Details | |
Reaction product of Crude sludge and Calcium oxide. Crude sludge is the mixture of by-products of petroleum hydrocarbons refining (especially Total petroleum hydrocarbons, Polycyclic aromatic hydrocarbons, acid-refined heavy petroleum distillates). The Crude sludge is neutralised by calcium oxide in the ratio 80:20. The maturing process proceeds under ambient conditions and takes for at least 3 days. Subsequently, the reaction product is processed mechanically | 930-592-4 | - | Reproductive toxicity (pre-natal developmental toxicity) | 20/09/2013 | 04/11/2013 | Details | |
Reaction product of Distillates (petroleum), acid-treated heavy naphthenic and calcium oxide | - | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/08/2011 | 30/09/2011 | Details | |
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda | 939-368-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
Reaction product of: polyethylene-polyamine-(C16-C18)-alkylamides with monothio-(C2)-alkyl phosphonates | 417-450-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 |
Details | |
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid | 701-230-0 | - | Long-term toxicity to fish | 10/05/2022 | 27/06/2022 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid | 946-533-0 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) | 23/04/2018 | 07/06/2018 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid | 946-533-0 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) | 16/12/2020 | 01/02/2021 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid | 938-645-3 | - |
Long-term toxicity to fish
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6) Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) Sub-chronic toxicity (90-day): oral
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) |
16/03/2015 16/03/2015 16/03/2015 |
30/04/2015 30/04/2015 30/04/2015 |
Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid | 931-291-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid | - | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 30/09/2011 30/09/2011 |
Details | |
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane | 410-560-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 |
Details | |
Reaction products of 5,5-dimethylhydantoin and ethylene oxide | 701-388-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
Reaction products of [3-(2,3-epoxypropoxy)propyl]trimethoxysilane and triacetoxyvinylsilane | 701-409-3 | - | Genetic toxicity in vivo | 25/01/2022 | 11/03/2022 | Details | |
Reaction products of adipic acid and 2,3-epoxypropyl C10-(branched) alkanoate | 825-846-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 |
Details | |
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl | 939-591-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) | 701-400-4 | - | Genetic toxicity in vivo | 25/11/2021 | 10/01/2022 | Details | |
Reaction products of amines, polyethylenepoly-, triethylenetetramine fraction and copper sulphate (1:1) | 701-399-0 | - | "Genetic toxicity in vivo || Note: testing proposed with Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) (EC 701-400-4)" | 25/11/2021 | 10/01/2022 | Details | |
Reaction products of anilinohydroxypolycyclicsulphonic acid coupled twice with diazotised aminonitrophenol, complexes with [3-hydroxy-4-[(2-hydroxy-1-polycyclic)azo]-7-nitropolycyclic-1-sulphonato(3-)]chromium, sodium salts | - | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Reaction products of boric acid and calcium dihydroxide and lithium hydroxide | 701-453-3 | - | Genetic toxicity in vivo||Note: testing proposed with diboron calcium tetraoxide (EC no. 237-224-5) | 22/09/2022 | 07/11/2022 | Details | |
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine | 931-216-1 | - | Long-term toxicity to fish || Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2) | 22/04/2021 | 07/06/2021 | Details | |
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia | 618-561-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallized with Basic Chromium (III) Sulphate, sodium salts | 947-395-4 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts | 939-382-7 | - | Genetic toxicity in vivo | 25/11/2021 | 10/01/2022 | Details | |
Reaction products of diazotised Sodium Picramate coupled with Resorcinol, subsequently coupled with diazotised 4'-Amino-4-Nitrodiphenylamin-2-Sulfonic Acid, at the end metallized with Iron (II) sulphate heptahydrate, sodium salts | 946-788-8 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Reaction products of diphenylamine with nonene, branched | 701-385-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/04/2022 | 16/05/2022 | Details | |
Reaction products of Isophorone diamine, Butyl glycidyl ether, and Bisphenol A diglicydyl ether | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
Reaction products of monoethanolamine and boric acid (1:1) | 701-025-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
Reaction products of monoethanolamine and boric acid (1:3) | 701-024-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 12/03/2020 |
Details | |
Reaction products of n-octanol and acrylic acid, first distillation pitch | 938-925-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
Reaction products of n-octanol and acrylic acid, first distillation pitch | 938-925-5 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Reaction products of orthoboric acid with 2,2'-iminodiethanol (1:1) | 701-083-2 | - |
"Reproductive toxicity (pre-natal developmental toxicity)
“||Note: testing proposed with MEA Polyborate (EC 701-025-6)” Sub-chronic toxicity (90-day): oral “||Note: testing proposed with MEA Polyborate (EC 701-025-6)” |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide | 701-196-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Reaction products of polyaminoalkane and substituted octadecanoic acid | 434-430-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2016 16/12/2016 |
30/01/2017 30/01/2016 |
Details | |
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide | 939-459-5 | - | Sub-chronic toxicity (90-day): oral | 30/11/2015 | 14/01/2016 | Details | |
Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction | 949-141-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Saccharomyces cerevisiae cell wall, extracted | 949-711-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
Shale oils, heavy | 930-690-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 14/03/2016 14/03/2016 |
02/01/2012 28/04/2016 28/04/2016 |
Details | |
Shale oils, light | 923-592-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” | 14/03/2016 | 28/04/2016 | Details | |
Shale oils, light | 923-592-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 17/11/2011 17/11/2011 |
02/01/2012 02/01/2012 02/01/2012 |
Details | |
Slags, steelmaking, elec. furnace (stainless/high alloy steel production) | 932-476-9 | - | Sub-chronic toxicity (90 day): inhalation | 06/03/2012 | 20/04/2012 | Details | |
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) | 947-369-2 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed | 941-809-7 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |
Soybean oil, oligomerized | 701-252-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/09/2018 | 22/10/2018 | Details | |
SUMILIZER GP | 442-450-4 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |