Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine | 217-461-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 |
Details | |
2-ethyl-4-methylimidazole | 213-234-5 | 931-36-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate | 204-793-6 | 126-57-8 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 17/04/2015 | 04/06/2015 | Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate | 403-960-2 | - | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
2-dibutylaminoethanol | 203-057-1 | 102-81-8 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
2-chloropropane | 200-858-8 | 75-29-6 | Reproductive toxicity (two-generation reproductive toxicity) | 16/05/2011 | 30/06/2011 | Details | |
2-chloropropane | 200-858-8 | 75-29-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated | 614-503-3 | 68441-62-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated | 614-503-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation |
15/04/2011 15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 30/05/2011 |
Details | |
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated | 614-503-3 | 68441-62-3 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed on rabbit. Reproductive toxicity (two-generation reproductive toxicity) |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
2-butyl-2-ethylpropanediol | 204-111-7 | 115-84-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 |
Details | |
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched | 283-219-6 | 84583-68-6 | Sub-chronic toxicity (90-day): oral | 12/04/2017 | 29/05/2017 | Details | |
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol | 286-304-6 | 85204-10-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
2-butene | 203-452-9 | 107-01-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation
|| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
2-butene | 203-452-9 | 107-01-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | 404-360-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 24/05/2013 | 08/07/2013 | Details | |
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol | 608-744-3 | 32472-85-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/03/2015 | 30/04/2015 | Details | |
2-aminopropane-1,3-diol | 208-584-0 | 534-03-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
2-aminoethanol, monoester with boric acid | 233-829-3 | 10377-81-8 | Sub-chronic toxicity (90-day): oral | 17/11/2011 | 02/01/2012 | Details | |
2-aminoethanol, monoester with boric acid | 233-829-3 | 10377-81-8 |
Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
2-amino-2-ethylpropanediol | 204-101-2 | 115-70-8 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 2-amino-1,3-propanediol Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 2-amino-1,3-propanediol |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate | 266-733-5 | 67584-55-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
2-[[(butylamino)carbonyl]oxy]ethyl acrylate | 264-036-0 | 63225-53-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 23/03/2020 | 07/05/2020 | Details | |
2-[2-(2-hydroxyethoxy)ethoxy]ethanol,methanesulfonic acid | 817-828-0 | 80322-82-3 | Genetic toxicity in vivo | 30/06/2023 | 14/08/2023 | Details | |
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate | 254-588-0 | 39670-09-2 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate | 701-363-4 | - | Sub-chronic toxicity (90-day): oral | 26/08/2021 | 11/10/2021 | Details | |
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate | 244-311-1 | 21282-97-3 | Genetic toxicity in vivo | 29/04/2014 | 13/06/2014 | Details | |
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide | 228-768-4 | 6358-31-2 | 7.5.2 Repeated dose toxicity: inhalation | 08/03/2024 | 22/04/2024 | Details | |
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate | 248-882-8 | 28173-59-3 | Genetic toxicity in vivo | 23/11/2020 | 07/01/2021 | Details | |
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate | 254-959-7 | 40530-60-7 | Genetic toxicity in vivo || Note: testing proposed with Disperse Red 302:1 (EC 248-882-8) | 23/11/2020 | 07/01/2021 | Details | |
2-(dimethylamino)-2-methylpropan-1-ol | 230-279-6 | 7005-47-2 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2014 | 17/03/2014 | Details | |
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene | 618-312-6 | 898566-17-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
2-(2H-benzotriazol-2-yl)-p-cresol | 219-470-5 | 2440-22-4 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
2-(2H-Benzotriazol-2-yl)-6-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)phenol | 422-600-5 | 73936-91-1 | Bioaccumulation aquatic / sediment | 01/04/2022 | 16/05/2022 | Details | |
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol | 221-573-5 | 3147-75-9 | Bioaccumulation aquatic / sediment | 15/07/2014 | 29/08/2014 | Details | |
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol | 274-570-6 | 70321-86-7 | Bioaccumulation aquatic / sediment | 15/07/2014 | 29/08/2014 | Details | |
2-(2-Vinyloxyethoxy)ethyl acrylate | 451-690-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 |
Details | |
2-(2-thienyl)ethyl toluene-p-sulphonate | 254-911-5 | 40412-06-4 | Genetic toxicity in vivo | 06/09/2018 | 22/10/2018 | Details | |
2-(2-naphthyloxy)ethanol | 202-228-8 | 93-20-9 | Genetic toxicity in vivo | 16/05/2014 | 30/06/2014 | Details | |
2-(2-methoxyethoxy)ethanol | 203-906-6 | 111-77-3 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2019 | 05/12/2019 | Details | |
2-(2-Ethoxyethoxy)-2-methylpropanee | 257-196-8 | 51422-54-9 | Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) | 03/02/2016 | 21/03/2016 | Details | |
2-(2-(2-methoxyethoxy)ethoxy)ethanol | 203-962-1 | 112-35-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
2-(2-(2-ethoxyethoxy)ethoxy)ethanol | 203-978-9 | 112-50-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
2-(2-(2-butoxyethoxy)ethoxy)ethanol | 205-592-6 | 143-22-6 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
2-(2-(2-butoxyethoxy)ethoxy)ethanol | 205-592-6 | 143-22-6 | Reproductive toxicity (pre-natal developmental toxicity): 1st PNDT on the registered substance 2nd PNDT with the registered substance // Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6) | 27/01/2020 | 12/03/2020 | Details | |
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate | 224-116-8 | 4203-89-8 | Genetic toxicity in vivo | 23/03/2020 | 07/05/2020 | Details | |
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts | 232-380-0 | 8011-86-7 | Genetic toxicity in vivo | 21/10/2021 | 07/12/2021 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (two-generation reproductive toxicity) | 14/02/2011 | 31/03/2011 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
2,6-di-tert-butylphenol | 204-884-0 | 128-39-2 | Bioaccumulation aquatic / sediment | 04/12/2023 | 18/01/2024 | Details | |
2,6-di-tert-butylphenol | 204-884-0 | 128-39-2 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2020 | 03/08/2020 | Details | |
2,6-di-tert-butylphenol | 204-884-0 | 128-39-2 | Sub-chronic toxicity (90-day): oral | 16/05/2011 | 30/06/2011 | Details | |
2,6,10-trimethyldodecane | 622-542-2 | 3891-98-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
2,6,10,15,19,23-hexamethyltetracosane | 203-825-6 | 111-01-3 | Bioaccumulation aquatic / sediment | 14/08/2014 | 28/09/2014 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (two-generation reproductive toxicity) | 02/02/2012 | 19/03/2012 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/07/2011 | 12/09/2011 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | 6.1.2 Long-term toxicity to fish | 08/03/2024 | 22/04/2024 | Details | |
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
2,5-di-tert-pentylhydroquinone | 201-222-2 | 79-74-3 | Sub-chronic toxicity (90-day): oral | 31/05/2011 | 15/07/2011 | Details | |
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone | 212-990-3 | 903-19-5 | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
2,4-Pentanedione, peroxide | 253-384-9 | 37187-22-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol | 411-220-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/09/2012 | 12/11/2012 | Details | |
2,4-dihydroxybenzophenone | 205-029-4 | 131-56-6 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
2,4-di-tert-butylphenol | 202-532-0 | 96-76-4 | Sub-chronic toxicity (90-day): oral | 16/05/2011 | 30/06/2011 | Details | |
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- | 485-230-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt | 286-344-4 | 85209-91-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated | 500-022-5 | 9014-85-1 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) || |
25/11/2019 | 09/01/2020 | Details | |
2,4,7,9-tetramethyl-4,7-decanediol | 451-160-7 | 17913-76-7 |
Long-term toxicity to fish "|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity) |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine | 426-040-2 | 25713-60-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 01/08/2011 |
Details | |
2,4,6-trinitrotoluene | 204-289-6 | 118-96-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
04/04/2014 04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 19/05/2014 |
Details | |
2,4,6-triallyloxy-1,3,5-triazine | 202-936-7 | 101-37-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
2,4,6-tri-tert-butylphenol | 211-989-5 | 732-26-3 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Sub-chronic toxicity (90-day): oral - |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2017 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 219-863-1 | 2554-06-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 17/04/2014 17/04/2014 |
Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) |
04/10/2013 04/10/2013 |
18/11/2013 18/11/2013 |
Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
|
Details |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) | 25/05/2020 | 09/07/2020 | Details | |
2,4,4-trimethylpentene | 246-690-9 | 25167-70-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 15/07/2022 | 29/08/2022 | Details | |
2,4,4-trimethylpentene | 246-690-9 | 25167-70-8 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint. Sub-chronic toxicity (90-day): oral |
26/03/2018 26/03/2018 |
11/05/2018 11/05/2018 |
Details | |
2,3-epoxypropyl o-tolyl ether | 218-645-3 | 2210-79-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid | 500-281-4 | 98362-33-5 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): dermal |
15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
26/05/2010 26/05/2010 26/05/2010 |
12/07/2010 12/07/2010 12/07/2010 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2,3-epoxypropyl isopropyl ether | 223-672-9 | 4016-14-2 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide | 686-241-8 | 81058-27-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
2,2`-iminodi(ethylamine),N-(2-aminoethyl)ethane-1,2-diamine | 203-865-4 | 111-40-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
05/04/2011 05/04/2011 05/04/2011 |
20/05/2011 20/05/2011 20/05/2011 |
Details | |
2,2`-(octadec-9-enylimino)bisethanol | 246-807-3 | 25307-17-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 29/08/2011 |
Details | |
2,2-dimethylpropane-1,3-diyl dibenzoate | 224-081-9 | 4196-89-8 | Reproductive toxicity (pre-natal developmental toxicity) | 29/02/2016 | 14/04/2016 | Details | |
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate | 255-180-5 | 41026-17-9 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2016 16/12/2016 16/12/2016 |
30/01/2017 30/01/2017 30/01/2017 |
Details | |
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate | 255-180-5 | 41026-17-9 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
2,2-dimethylpropan-1-ol, tribromo derivative | 253-057-0 | 36483-57-5 | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |