Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1 - 25 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
(E)-2-benzylideneoctanal	639-566-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/04/2011 15/04/2011	30/05/2011 30/05/2011	Details
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated	926-000-9	-	Reproductive toxicity (pre-natal developmental toxicity)	04/04/2014	19/05/2014	Details
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid	701-116-0	-	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol	204-137-9	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012 16/01/2012	01/03/2012 01/03/2012 01/03/2012	Details
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol	701-393-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol	701-124-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol	701-173-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol	701-041-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives	-	-	Sub-chronic toxicity (90-day): oral	30/06/2016	15/08/2016	Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters	701-339-3	-	Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020	09/07/2020	Details
1,3- and 1,4-cyclohexandicarboxyaldehyde	482-020-3	-	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs.	445-790-1	-	Sub-chronic toxicity (90 day): inhalation	04/04/2014	19/05/2014	Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate	931-295-2	-	Sub-chronic toxicity (90-day): oral	25/05/2020	09/07/2020	Details
1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester	701-012-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/12/2018 10/12/2018	24/01/2019 24/01/2019	Details
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE	921-042-4	-	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol	412-300-2	-	Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021	05/04/2021	Details
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine	411-930-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol	701-029-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts	939-457-4	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts	939-455-3	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether	926-564-6	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/10/2019 21/10/2019	05/12/2019 05/12/2019	Details
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid	225-306-3	-	Reproductive toxicity (pre-natal developmental toxicity study) Sub-chronic oral toxicity (90-day): oral	05/04/2011 05/04/2011	20/05/2011 20/05/2011	Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl-	485-230-3	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
2,4-dimethyl-6-(1-methyl-pentadecyl)phenol	411-220-5	-	Reproductive toxicity (pre-natal developmental toxicity)	25/09/2012	12/11/2012	Details
2-(2-Vinyloxyethoxy)ethyl acrylate	451-690-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/12/2017 20/12/2017	05/02/2018 05/02/2018	Details

Showing 1 - 25 of 2,011 results.

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