Ugrás a tartalomhoz
Ugrás a tartalomhoz

Korábbi/eredmények

Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Phosphoric acid, butyl ester 235-826-2 12788-93-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
Phosphoric acid, dodecyl ester, potassium salt 254-414-3 39322-78-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Poly-(1,4-diisopropylbenzol) 449-400-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-omega-hydroxy-, ether with 2,6 bis{[(2-hydroxyethyl)amino]methyl}-4-nonylphenol 614-668-1 68610-97-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2015
30/09/2015
16/11/2015
16/11/2015
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)  701-184-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Quaternary ammonium compounds, C12-18-alkylbis(hydroxyethyl)methyl, chlorides 276-038-9 71808-53-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 700-961-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran 939-429-1 16409-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Reaction mass of 2,2',2''-nitrilotriethanol and disodium succinate and sodium acetate and sodium bromide 905-908-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid 940-877-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/03/2019
29/03/2019
13/05/2019
13/05/2019
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol 941-357-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
08/02/2017
08/02/2017
27/03/2017
27/03/2017
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol 938-572-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
22/10/2018
22/10/2018
Reaction mass of 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol and propylidynetrimethanol 904-153-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol 939-071-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt 445-040-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol 939-719-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Reaction products of Isophorone diamine, Butyl  glycidyl ether, and Bisphenol A diglicydyl ether - -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
22/06/2017
22/06/2017
07/08/2017
07/08/2017
Reaction products of polyaminoalkane and substituted octadecanoic acid 434-430-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2016
16/12/2016
30/01/2017
30/01/2016
Sodium 3-(allyloxy)-2-hydroxypropanesulphonate 258-004-5 52556-42-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Sodium 4-oxovalerate 243-378-4 19856-23-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
Sodium hexahydroxoantimonate 251-735-0 33908-66-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
sodium O,O-diethyl dithiophosphate || Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5) 222-079-2 3338-24-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Sodium O,O-diisobutyl dithiophosphate 258-508-5 53378-51-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
tert-butyl peroxyneodecanoate 247-955-1 26748-41-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/06/2014
17/06/2014
01/08/2014
01/08/2014
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
tert-pentyl hydroperoxide 222-321-7 3425-61-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
07/10/2016
07/10/2016
21/11/2016
21/11/2016
Tetra(isobutyl)thioperoxydicarbamic acid 221-312-5 3064-73-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2018
18/06/2018
02/08/2018
02/08/2018
tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate 474-870-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Tri(isopropyl)silyl acrylate 457-670-6 157859-20-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Tricyclodecanedimethanol 248-096-5 26896-48-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Triethyl phosphonoacetate 212-757-6 867-13-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
29/08/2014
29/08/2014
Trinonyl benzene-1,2,4-tricarboxylate 252-552-9 35415-27-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
03/01/2017
03/01/2017
tri{[(2s)-1-ethoxy-1-oxopropan-2-yl]oxy}(vinyl)silane 701-301-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl 445-760-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/07/2015
31/07/2015
14/09/2015
14/09/2015
Ureidopropyltrialkoxysilane 449-160-7 116912-64-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
α,α,α',α'-tetramethylxylene-α,α-diol 248-256-4 27138-01-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): ora
07/10/2016
07/10/2016
21/11/2016
21/11/2016
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate 915-277-1 32052-51-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
5-methylheptan-3-one 208-793-7 541-85-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Isopropylcyclohexane 211-792-4 696-29-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda 939-368-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Triethoxypropylsilane 219-842-7 2550-02-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate 600-028-9 1001254-87-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): dermal
02/06/2014
02/06/2014
17/07/2014
17/07/2014
2,2'-p-phenylenedioxydiethanol 203-197-3 104-38-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
2,4,6-triallyloxy-1,3,5-triazine 202-936-7 101-37-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
15/04/2011
15/04/2011
30/05/2011
30/05/2011
2-aminopropane-1,3-diol 208-584-0 534-03-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
17/06/2014
17/06/2014
01/08/2014
01/08/2014
O-isopropyl ethylthiocarbamate 205-517-7 141-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Destillation fraction of chlorosilanes 700-717-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation 
16/05/2012
16/05/2012
02/07/2012
02/07/2012
1,1,3,3-tetramethyldisiloxane 221-906-4 3277-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine 309-629-8 100545-48-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Pentan-2-one 203-528-1 107-87-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/02/2014
18/02/2014
04/04/2014
04/04/2014
potassium tetrafluoroborate 237-928-2 14075-53-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
tetrahydro-2-methylfuran 202-507-4 96-47-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
23/01/2015
23/01/2015
09/03/2015
09/03/2015
Trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide 700-597-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
18/06/2012
18/06/2012
02/08/2012
02/08/2012
(1-hydroxycyclohexyl) (phenyl)methanone (hydroxycyclohexyl phenyl ketone) 213-426-9 947-19-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
28/02/2011
14/04/2011
14/04/2011
14/04/2011
(no public substance name available) 434-430-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues 271-832-1 68609-68-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
2,2'-azobis[2-methylbutyronitrile] 236-740-8 13472-08-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
03/03/2014
17/04/2014
17/04/2014
17/04/2014
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
2,2`-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
2,3-epoxypropyl o-tolyl ether 218-645-3 2210-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
2,6,10-trimethyldodecane 622-542-2 3891-98-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate 266-733-5 67584-55-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
2-ethylhexyl benzoate 226-641-8 5444-75-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
4-methylmorpholine 4-oxide, monohydrate 231-391-8 7529-22-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
9-Octadecenoic acid (Z)-, sulfonated, potassium salts 271-843-1 68609-93-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Alkenes, C10-14 288-213-7 85681-75-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
25/06/2012
31/10/2011
31/10/2011
09/08/2012
Alkenes, C11-12 931-515-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/11/2011
03/11/2011
25/06/2012
19/12/2011
19/12/2011
09/08/2012
Alkenes, C11-12, hydroformylation products, distn. residues 292-427-6 90622-27-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Alkenes, C13-14, hydroformylation products, distn. Residues 292-429-7 90622-29-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Alkenes, C15-18 297-797-2 93762-80-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
25/06/2012
30/09/2011
30/09/2011
09/08/2012
Alkenes, C16-18 900-050-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
25/06/2012
30/09/2011
30/09/2011
09/08/2012
Alkenes, C20-24 α- 300-202-1 93924-10-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Alkenes, C21-32 linear and branched 931-505-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
25/06/2012
31/10/2011
31/10/2011
09/08/2012
Alkenes, C24-28 α- 300-203-7 93924-11-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Alkenes, C8-10, C9-rich 271-212-0 68526-55-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
25/06/2012
12/09/2011
12/09/2011
09/08/2012
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2011
16/05/2011
16/05/2011
30/06/2011
30/06/2011
30/06/2011
Benzene-1,2,4-tricarboxylic acid 1,2-anhydride, oligomeric reaction products with ethane-1,2-diol and glycerol 500-199-9 68183-39-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Bis(2,3-epoxypropyl) terephthalate 230-565-0 7195-44-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
16/05/2012
02/07/2012
02/07/2012
02/07/2012
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine 239-816-9 15721-78-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
Boric acid (H3BO3), reaction products with ethanolamine 302-207-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
C26-28 (even numbered) α-alkenes 934-268-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2012
18/06/2012
18/06/2012
02/08/2012
02/08/2012
02/08/2012
Cobalt 231-158-0 7440-48-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt (II) dinitrate 233-402-1 10141-05-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt dihydroxide 244-166-4 21041-93-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt hydroxide oxide 234-614-7 12016-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt oxalate 212-409-3 814-89-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt oxide 215-154-6 1307-96-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt sulphide 215-273-3 1317-42-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(2+) propionate 216-333-1 1560-69-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) carbonate 208-169-4 513-79-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt(II) diacetate 200-755-8 71-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cobalt, borate neodecanoate complexes 270-601-2 68457-13-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Cyclohexyldimethoxymethylsilane 402-140-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/01/2012
16/01/2012
16/01/2012
01/03/2012
01/03/2012
01/03/2012
Dec-1-ene 212-819-2 872-05-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Decene 246-870-7 25339-53-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Dicyclopentyldimethoxysilane 404-370-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2011
16/12/2011
16/12/2011
30/01/2012
30/01/2012
30/01/2012
Dodec-1-ene 203-968-4 112-41-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Dodecene, hydroformylation products, high boiling 271-239-8 68526-91-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Hex-1-ene 209-753-1 592-41-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Hexadec-1-ene 211-105-8 629-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Hexadecene 248-131-4 26952-14-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Hydrocarbons, C12-30, olefin-rich, ethylene polymn. by-product 272-762-4 68911-05-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
25/06/2012
30/09/2011
30/09/2011
09/08/2012
N-(C16-C18)alkyl(C16-C18)alkane-1-amine 629-721-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
Nonene 248-339-5 27215-95-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Oct-1-ene 203-893-7 111-66-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Octadec-1-ene 204-012-9 112-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Octene, hydroformylation products, high-boiling 271-237-7 68526-89-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Pentaerythritol tetrakis(3-mercaptopropionate) 231-472-8 7575-23-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide 423-340-5 162881-26-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
22/12/2010
22/12/2010
22/12/2010
07/02/2011
07/02/2011
07/02/2011
Reaction mass of 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched and 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched acetate 931-295-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Reaction mass of Alkenes C20-24 and Alkenes C24-28 931-746-3 93924-10-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/11/2011
03/11/2011
16/07/2012
19/12/2011
19/12/2011
30/08/2012
Reaction mass of cobalt and copper and iron 912-664-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Reaction mass of cobalt sulphide and nickel sulphide and trinickel disulphide 910-663-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
S-(3-(triethoxysilyl)propyl)octanethioate 436-690-9 220727-26-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
25/09/2012
25/09/2012
25/09/2012
12/11/2012
12/11/2012
12/11/2012
Shale oils 269-646-0 68308-34-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
17/11/2011
17/11/2011
02/01/2012
02/01/2012
02/01/2012
Shale oils, heavy 930-690-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
14/03/2016
14/03/2016
02/01/2012
28/04/2016
28/04/2016
Shale oils, light 923-592-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
17/11/2011
17/11/2011
02/01/2012
02/01/2012
02/01/2012
Tetradec-1-ene 214-306-9 1120-36-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2011
31/05/2011
25/06/2012
15/07/2011
15/07/2011
09/08/2012
Tricobalt tetraoxide 215-157-2 1308-06-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Tris(2,5,8,11-tetraoxatridecyl) orthoborate 310-290-3 161907-80-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
28/02/2011
14/04/2011
14/04/2011
14/04/2011
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): most appropriate route
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylated 614-503-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): inhalation
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/03/2011
15/03/2011
15/03/2011
29/04/2011
29/04/2011
29/04/2011
1,6-bis(2,3-epoxypropoxy)hexane 240-260-4 16096-31-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): dermal
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine 605-296-0 162627-17-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs. 276-014-8 71786-60-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
1,3-dioxepane 208-015-6 505-65-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
2,4,6-trinitrotoluene 204-289-6 118-96-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
04/04/2014
04/04/2014
04/04/2014
19/05/2014
19/05/2014
19/05/2014
2-ethylhexyl nitrate 248-363-6 27247-96-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Perfluoroethane 200-939-8 76-16-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Reaction mass of 2,2'-oxydibutane and 2-methylpropan-2-ol and butan-2-ol and 2,2'-oxydipropane 903-919-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
Reaction mass of 2-methylpent-2-ene and diisopropyl ether 906-484-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
Slags, phosphorus-manufg. 273-732-3 69012-32-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): dermal
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane 618-939-5 933999-84-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): dermal
18/11/2014
18/11/2014
18/11/2014
02/01/2015
02/01/2015
02/01/2015
Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant.
Sub-chronic toxicity (90 day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate 940-592-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Cobalt (II) sulphate 233-334-2 10124-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) ; after obtaining results of the 90-day subchronic toxicity study
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
(E)-2-benzylideneoctanal 639-566-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] 244-617-5 21850-44-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/09/2014
18/09/2014
03/11/2014
03/11/2014
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 271-082-5 68515-40-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt 262-872-0 61617-00-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
3,6,9,12-tetraazatetradecamethylenediamine 223-775-9 4067-16-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
28/02/2011
28/02/2011
14/04/2011
14/04/2011
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane 260-350-7 56706-10-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Alkenes C20+ 931-467-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Alkenes, C10-13 287-479-1 85535-87-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Alkenes, C13-14 - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Alkenes, C6-8, even and odd, linear and branched - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction 308-482-7 98072-31-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/08/2011
01/08/2011
15/09/2011
15/09/2011
Aluminium tris(dialkylphosphinate) - -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
23/06/2011
23/06/2011
08/08/2011
08/08/2011
Amines, polyethylenepoly- 268-626-9 68131-73-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
28/02/2011
28/02/2011
14/04/2011
14/04/2011
Aminoiminomethanesulphinic acid 217-157-8 1758-73-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
18/02/2013
18/02/2013
04/04/2013
04/04/2013
Asphalt, oxidized 265-196-4 64742-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Barium carbonate 208-167-3 513-77-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Barium hydroxide 241-234-5 17194-00-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
benzyl 3-isobutyryloxy-1-isopropyl-2,2-dimethylpropyl phthalate 240-920-1 16883-83-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Bis(2-chloroethoxy)methane 203-920-2 111-91-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
31/03/2011
31/03/2011
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons 700-762-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
25/09/2012
25/09/2012
12/11/2012
12/11/2012
calcium cyanamide 205-861-8 156-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Dodecene 246-922-9 25378-22-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized 931-203-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Fatty acids, C16-18 (even numbered), reaction products with triethanolamine, di-Me sulfate-quaternized 931-209-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Fatty acids, C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized 931-216-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Hexacos-1-ene 242-615-9 18835-33-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Hydrocarbons, C9-unsaturated, polymerized 615-276-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Icos-1-ene 222-374-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
N-vinylformamide 236-102-9 13162-05-5
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
15/08/2011
15/08/2011
Octacos-1-ene 242-616-4 18835-34-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Octadecene 248-205-6 27070-58-2
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Phenol, methylstyrenated 270-966-8 68512-30-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Reaction mass of 2,6-Octadien-1-ol, 3,7-dimethyl-, (E) and 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)- 906-125-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
15/08/2011
15/08/2011
Reaction mass of bis(2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-1,10-decanedioate and 1,8-bis[(2,2,6,6-tetramethyl-4-((2,2,6,6-tetramethyl-1-octyloxypiperidin-4-yl)-decan-1,10-dioyl)piperidin-1-yl)oxy]octane 406-750-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
04/06/2012
04/06/2012
19/07/2012
19/07/2012
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene 931-893-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Reaction mass of Rosin, hydrogenated and [1R-(1a,4ß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid 911-238-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Reaction products of 2-(4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-hydroxy phenol with ((C10-16, rich in C12-13 alkyloxy)methyl)oxyrane 410-560-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/01/2012
16/01/2012
01/03/2012
01/03/2012
Residues (petroleum), distn. residue hydrogenation 309-712-9 100684-39-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Residues (petroleum), thermal cracked vacuum 295-518-9 92062-05-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Residues (petroleum), vacuum 265-057-8 64741-56-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Residues (petroleum), vacuum distn. residue hydrogenation 309-713-4 100684-40-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Sodium N-lauroylsarcosinate 205-281-5 137-16-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Terpineol 232-268-1 8000-41-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
15/08/2011
15/08/2011
Tetradecene 248-130-9 26952-13-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Tridecene 246-919-2 25377-82-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
15/07/2011
15/07/2011
Resin acids and Rosin acids, esters with pentaerythritol 232-479-9 8050-26-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
06/03/2012
02/07/2013
02/07/2013
02/07/2013
20/04/2012
16/08/2013
16/08/2013
16/08/2013
Rosin 232-475-7 8050-09-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with rosin CAS 8050-09-7; Rosin, hydrogenated (CAS RN 65997-06-0), Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)
06/03/2012
02/07/2013
02/07/2013
02/07/2013
20/04/2012
16/08/2013
16/08/2013
16/08/2013
Rosin, fumarated 266-040-8 65997-04-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with the registered substance (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
06/03/2012
02/07/2013
02/07/2013
02/07/2013
20/04/2012
16/08/2013
16/08/2013
16/08/2013
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and tetraethylenepentamine 500-289-8 103758-98-1
Reproductive toxicity (pre-natal developmental toxicity) ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
Sub-chronic toxicity (90-day): oral ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
16/03/2015
16/03/2015
30/04/2015
30/04/2015
2,4,4-trimethylpentene 246-690-9 25167-70-8
Reproductive toxicity (pre-natal developmental toxicity) || Note: There are two testing proposals for this endpoint.
Sub-chronic toxicity (90-day): oral
26/03/2018
26/03/2018
11/05/2018
11/05/2018



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