Korábbi/eredmények
Korábbi/eredmények
Korábbi/eredmények
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol | 941-496-7 | 1689576-89-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
Fatty acids, tall-oil, di- and triesters with trimethylolpropane | 941-376-4 | - |
Long-term toxicity to aquatic invertebrates Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Testing proposed with EC No 931-531-4. |
31/05/2016 31/05/2016 31/05/2016 |
15/07/2016 15/07/2016 15/07/2016 |
Details | |
3-methyldecane; benzene; cyclooctane; nonane | 941-364-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 05/07/2018 | 20/08/2018 | Details | |
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) | 941-357-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol | 941-357-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
08/02/2017 08/02/2017 |
27/03/2017 27/03/2017 |
Details | |
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester | 941-267-1 | 1445870-18-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated | 941-216-3 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue | 941-212-1 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate | 941-152-6 | - | Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) | 15/07/2022 | 29/08/2022 | Details | |
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid | 940-877-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/03/2019 29/03/2019 |
13/05/2019 13/05/2019 |
Details | |
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane | 940-783-4 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 ) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate | 940-592-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
Fatty acids, tall oil and rosin reacted with maleic anhydride | 940-281-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) //Note:testing to be done with rosin maleated (CAS 8050-28-0) Sub-chronic toxicity (90-day): oral. //Note:testing to be done with rosin maleated (CAS 8050-28-0) |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate | 940-272-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 16/10/2017 |
Details | |
Nonanoic acid (branched), 2-oxiranylmethyl ester | 940-029-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) |
20/09/2013 20/09/2013 20/09/2013 |
04/11/2013 04/11/2013 04/11/2013 |
Details | |
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol | 939-719-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) | 939-717-7 | - | Sub-chronic toxicity (90-day): oral | 02/06/2014 | 17/07/2014 | Details | |
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - | Long-term toxicity to fish | 25/11/2019 | 09/01/2020 | Details | |
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) | 939-700-4 | - | Sub-chronic toxicity (90-day): oral | 21/10/2019 | 05/12/2019 | Details | |
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts | 939-691-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Sub-chronic toxicity (90-day): oral | 10/05/2022 | 27/06/2022 | Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Distilled tall oil, magnesium salts | 939-629-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics | 939-601-6 | - | Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics | 02/06/2014 | 17/07/2014 | Details | |
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate | 939-595-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl | 939-591-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide | 939-581-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/03/2018 | 11/05/2018 | Details | |
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form | 939-559-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
Fatty acid chlorides, C18 unsatd., reaction products with sodium N-methyltaurinate | 939-538-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 |
Details | |
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt | 939-513-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine | 939-485-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide | 939-459-5 | - | Sub-chronic toxicity (90-day): oral | 30/11/2015 | 14/01/2016 | Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-457-4 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-455-3 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) | 939-448-5 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran | 939-429-1 | 16409-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
Fatty acids, tall-oil, reaction products with acrylic acid | 939-424-4 | - | Long-term toxicity to fish | 04/04/2014 | 19/05/2014 | Details | |
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- | 939-401-9 | 1469983-41-2 | Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) | 15/07/2022 | 29/08/2022 | Details | |
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts | 939-382-7 | - | Genetic toxicity in vivo | 25/11/2021 | 10/01/2022 | Details | |
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine | 939-379-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda | 939-368-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid | 939-201-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol | 939-071-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - | Sub-chronic toxicity (90-day): oral | 21/12/2021 | 04/02/2022 | Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |