Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

2 011 eredményből 201 - 400 megmutatása.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Genetic toxicity in vivo	23/11/2020	07/01/2021	Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Reaction mass of dipotassium 3,3'-sulphonylbis(benzenesulphonate) and potassium 3-(phenylsulphonyl)benzenesulphonate	915-932-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Fatty acids, C18 (linear and branched, unsaturated) and fatty acids C18 (linear and branched, unsaturated) -N,N-dibutylamide, monosulphated, sodium salts	915-926-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/11/2020 23/11/2020	07/01/2021 07/01/2021	Details
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs.	915-790-0	-	Sub-chronic toxicity (90-day): oral	12/12/2014	26/01/2015	Details
Reaction mass of Sodiumbis[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodium [1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)][1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-) and Sodiumbis[1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphtholato(2-)]chromate(1-)	915-756-5	-	Genetic toxicity in vivo	21/12/2021	04/02/2022	Details
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane	915-748-1	-	Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6) Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6)	17/06/2014 17/06/2014	01/08/2014 01/08/2014	Details
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane	915-748-1	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6)	25/05/2020	09/07/2020	Details
Reaction mass of Bis(1,2,2,6,6-pentamethyl-4-piperidyl) sebacate and Methyl 1,2,2,6,6-pentamethyl-4-piperidyl sebacate	915-687-0	-	Genetic toxicity in vivo	15/09/2011	31/10/2011	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Sub-chronic toxicity (90-day): oral	21/10/2021	07/12/2021	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/07/2011 15/07/2011	29/08/2011 29/08/2011	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Reproductive/developmental toxicity	22/12/2010	07/02/2011	Details
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate	915-657-7	-	Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)	19/07/2013 19/07/2013	02/09/2013 02/09/2013	Details
Reaction mass of 3-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde and 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde	915-650-9	-	Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8) Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with 3-CYCLOHEXENE-1-CARBOXALDEHYDE MULTICONSTITUENT (EC no. 253-617-4) (EC no. 257-943-8)	04/09/2023 04/09/2023	19/10/2023 19/10/2023	Details
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone	915-623-1	-	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2014	30/05/2014	Details
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinone	915-623-1	-	Genetic toxicity in vivo Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone	915-623-1	-	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	27/09/2017 27/09/2017 27/09/2017	13/11/2017 13/11/2017 13/11/2017	Details
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate	915-568-3	-	Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)	19/07/2013 19/07/2013	02/09/2013 02/08/2013	Details
Reaction mass of 2,5,8,11-tetraoxatridecan-13-ol and 2,5,8,11,14-pentaoxahexadecan-16-ol	915-389-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC no. 203-962-1)	01/04/2022	16/05/2022	Details
Reaction mass of 1-phenyloctadecane-1,3-dione and phenylicosane-1,3-dione	915-316-2	-	Reproductive toxicity (pre-natal developmental toxicity)	06/03/2012	20/04/2012	Details
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate	915-277-1	32052-51-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Reaction mass of cobalt and copper and iron	912-664-7	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]-	911-819-6	-	Long-term toxicity to fish	31/01/2023	17/03/2023	Details
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol	911-819-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/08/2019 16/08/2019	30/09/2019 30/09/2019	Details
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol	911-819-6	-	Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral	14/02/2011 14/02/2011	31/03/2011 31/03/2011	Details
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]-	911-811-2	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/04/2015 17/04/2015 17/04/2015	04/06/2015 04/06/2015 04/06/2015	Details
Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate	911-616-2	-	Sub-chronic toxicity (90-day): oral	25/05/2020	09/07/2020	Details
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]-	911-490-9	-	Sub-chronic toxicity (90-day): oral	27/05/2019	11/07/2019	Details
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]-	911-490-9	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	18/11/2014 18/11/2014	02/01/2015 02/01/2015	Details
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane	911-381-6	-	Long-term toxicity to fish \|\| Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
Reaction mass of diisobutyl hydrogen phosphate and isobutyl dihydrogen phosphate	911-351-2	-	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
Reaction mass of 2-tert-butyl-4,6-dimethylphenol and 4-tert-butyl-2,5-dimethylphenol	911-254-5	-	Reproductive toxicity (pre-natal developmental toxicity)	16/06/2011	01/08/2011	Details
Reaction mass of hydrogenated and dehydrogenated rosin	911-238-8	-	Reproductive toxicity (pre-natal developmental toxicity)\|\| Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)	19/07/2013 19/07/2013	02/09/2013 02/09/2013	Details
Reaction mass of Rosin, hydrogenated and [1R-(1a,4ß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid	911-238-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/03/2011 15/03/2011	29/04/2011 29/04/2011	Details
Benzene, diethenyl- and Benzene, ethenylethyl-	910-757-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/08/2019 16/08/2019	30/09/2019 30/09/2019	Details
Reaction mass of cobalt sulphide and nickel sulphide and trinickel disulphide	910-663-6	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/09/2011 02/09/2011 02/09/2011	17/10/2011 17/10/2011 17/10/2011	Details
Reaction mass of methyl dihydrogen phosphate and orthophosphoric acid and dimethyl hydrogen phosphate	908-996-7	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1). Sub-chronic toxicity (90-day): oral \|\| Note: Testing is proposed with Phosphoric acid, butyl ester (CAS 12788-93-1).	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
Reaction mass of 1-chlorobut-2-ene and 3-chlorobut-1-ene	908-820-9	-	Genetic toxicity in vivo	16/07/2012	30/08/2012	Details
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol	907-996-4	-	Reproductive toxicity (pre-natal developmental toxicity) 1st and 2nd PNDTs: \|\| Note: testing proposed with 2-92-92-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)	27/01/2020	12/03/2020	Details
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol	907-996-4	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)	10/08/2018	24/09/2018	Details
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol	907-996-4	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)	27/05/2019	11/07/2019	Details
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate	907-870-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\|Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 )	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine	907-495-0	-	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022 01/04/2022	16/05/2022 16/05/2022	Details
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis-	907-495-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit Sub-chronic toxicity (90 day): inhalation	27/05/2019 27/05/2019 27/05/2019	11/07/2019 11/07/2019 11/07/2019	Details
Reaction mass of 2-methylpent-2-ene and diisopropyl ether	906-484-8	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	29/07/2011 29/07/2011 29/07/2011	12/09/2011 12/09/2011 12/09/2011	Details
Reaction mass of 2,6-Octadien-1-ol, 3,7-dimethyl-, (E) and 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-	906-125-5	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	01/07/2011 01/07/2011	15/08/2011 15/08/2011	Details
Reaction mass of benzyl 2-ethylhexyl adipate and bis(2-ethylhexyl) adipate and dibenzyl adipate	905-983-8	-	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
Reaction mass of 2,2',2''-nitrilotriethanol and disodium succinate and sodium acetate and sodium bromide	905-908-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014	05/05/2014 05/05/2014	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl	905-837-3	-	Long-term toxicity to fish \|\| Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4)	26/08/2021	11/10/2021	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate	905-806-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
Reaction mass of (4R)-isopropenyl-1-methylcyclohexene and (4S)-isopropenyl-1-methylcyclohexene and 1-isopropyl-4-methylcyclohexa-1,3-diene and 1-isopropyl-4-methylcyclohexa-1,4-diene and 4-isopropylidene-1-methylcyclohexene	905-474-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/10/2023 03/10/2023	17/11/2023 17/11/2023	Details
Reaction mass of 1-methyl-4-(1-methylethylidene)cyclohexyl acetate and p-menth-1-en-8-yl acetate	904-693-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	04/09/2023	19/10/2023	Details
Reaction mass of 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol and propylidynetrimethanol	904-153-2	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details
Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol	904-153-2	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	18/02/2021	05/04/2021	Details
Reaction mass of 2,2'-oxydibutane and 2-methylpropan-2-ol and butan-2-ol and 2,2'-oxydipropane	903-919-3	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	29/07/2011 29/07/2011 29/07/2011	12/09/2011 12/09/2011 12/09/2011	Details
Alkenes, C16-18	900-050-1	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011 25/06/2012	30/09/2011 30/09/2011 09/08/2012	Details
di-p-tolyl(2,4,6-trimethylbenzoyl)phosphine oxide	884-585-5	270586-78-2	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/06/2023 30/06/2023 30/06/2023	14/08/2023 14/08/2023 14/08/2023	Details
Copper(I, II) sulfite	884-197-6	15293-86-4	7.6.2 Genetic toxicity in vivo\|\|Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8)	08/03/2024	22/04/2024	Details
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea	876-151-9	2292123-68-1	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	03/04/2023 03/04/2023	22/05/2023 22/05/2023	Details
Di(tetraethylammonium)hexahydroxoplatinate(IV)	848-537-7	1912392-88-1	Genetic toxicity in vivo	21/09/2020	05/11/2020	Details
reaction products of benzaldehyde diethylenetriamine and triethylenetetramine, hydrogenated	846-447-2	1219458-07-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine]	835-183-3	83420-16-0	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
Reaction products of acrylic acid with 2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol]	830-217-3	1393932-71-2	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Link to registration dossier not given as the dossier not yet disseminated Sub-chronic toxicity (90-day): oral \|\| Note: Link to registration dossier not given as the dossier not yet disseminated	24/01/2019 24/01/2019	11/03/2019 11/03/2019	Details
Reaction products of adipic acid and 2,3-epoxypropyl C10-(branched) alkanoate	825-846-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/06/2022 16/06/2022	01/08/2022 01/08/2022	Details
2-hydroxy-3-propyl-2H-furan-5-one	821-451-7	78920-10-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant. \|\|	25/11/2019	09/01/2020	Details
Zinc, O,O-mixed (iso-Bu), (iso-Pr), (pentyl) phosphorodithioate	820-225-5	101747-77-7	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Sub-chronic toxicity (90-day): oral “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)	26/04/2019 26/04/2019 26/04/2019	10/06/2019 10/06/2019 10/06/2019	Details
2-[2-(2-hydroxyethoxy)ethoxy]ethanol,methanesulfonic acid	817-828-0	80322-82-3	Genetic toxicity in vivo	30/06/2023	14/08/2023	Details
Dialkyl-methyl-dihydro-heteropolycyle	815-131-6	913171-06-9	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/03/2020	07/05/2020	Details
1-Dodecene, dimers	814-509-8	62132-67-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 1-decene, homopolymer, hydrogenated (EC 500-183-1), 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-decene, dimer, unhydrogenated (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the Substance, 1-decene, homopolymer, hydrogenated (EC 500-183-1), and 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)	18/03/2021 18/03/2021 18/03/2021	03/05/2021 03/05/2021 03/05/2021	Details
1-Dodecene, dimers	814-509-8	62132-67-6	Reproductive toxicity (pre-natal developmental toxicity)	02/11/2018	17/12/2018	Details
4,8-Dimethyl-2,5,7,10-tetraoxaundecane	813-999-0	59039-15-5	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Peroxyacetic acid, reaction products with N2,N2’-1,6-hexanediylbis[N4,N6-dibutyl-N2,N4,N6-tris(2,2,6,6,tetramethyl-4-piperidinyl)-1,3,5-triazine-2,4,6-triamine, hydrogenated	812-927-5	1902936-62-2	Reproductive toxicity (pre-natal developmental toxicity)	10/08/2018	24/09/2018	Details
Strontium neodecanoate	812-724-1	106705-37-7	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Strontium oxide] (EC 215-219-9)	26/04/2019	10/06/2019	Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-491-6	1312943-23-9	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-490-0	1312943-21-7	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
2,2-dimethyl-3-oxopropyl acetate	811-188-6	16184-79-5	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	01/09/2017	16/10/2017	Details
Reaction products of 2-hydroxyethyl methacrylate and diphosphorus pentaoxide	810-703-1	1187441-10-6	Genetic toxicity in vivo	23/03/2020	07/05/2020	Details
N-(2-ethylhexyl)isononan-1-amide	810-288-7	1700656-13-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Bis(O,O-diisopropyl dithiophosphate)bis(cyclohexylamine) zinc	809-986-4	52585-16-7	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
Zinc, bis[O,O-bis(1-methylethyl) phosphorodithioato-.kappa.S]bis(cyclohexanamine)-, (T-4)-	809-986-4	52585-16-7	Genetic toxicity in vivo	18/06/2018	02/08/2018	Details
3-Ethenyl-5-methyl-2-oxazolidinone	809-852-5	3395-98-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/09/2017 27/09/2017	13/11/2017 13/11/2017	Details
(2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl prop-2-enoate	807-159-2	69701-99-1	Genetic toxicity in vivo	26/10/2022	12/12/2022	Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene)	807-130-4	53716-82-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene	807-113-1	3709-71-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	19/10/2020 19/10/2020	03/12/2020 03/12/2020	Details
1,5-Diisocyanatopentane	807-040-5	4538-42-5	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide	806-543-7	215917-77-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide	806-543-7	215917-77-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	30/11/2015	14/01/2016	Details
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid	806-510-7	1393571-43-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated)	05/06/2014 05/06/2014	21/07/2014 21/07/2014	Details
Fatty acids, C16-18 and C18-unsatd., branched and linear, reaction products with diethylenetriamine and tall-oil fatty acids, Me maleates	806-509-1	1393571-42-0	Reproductive toxicity (pre-natal developmental toxicity)	05/06/2014	21/07/2014	Details
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and maleic anhydride	806-508-6	1419212-77-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral Note: testing proposed with substance Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS: 1419212-76-2)	05/06/2014 05/06/2014	21/07/2014 21/07/2014	Details
3-[(3-{[(3-acetoxy-2,2-dimethylpropylidene)amino]methyl}-3,5,5-trimethylcyclohexyl)imino]-2,2-dimethylpropyl acetate	805-722-7	1064082-81-0	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	17/12/2019	31/01/2020	Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene	801-941-7	1404190-37-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/10/2016 20/10/2016	05/12/2016 05/12/2016	Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene	801-941-7	1404190-37-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/05/2016 31/05/2016	15/07/2016 15/07/2016	Details
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde	801-656-8	1416808-92-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	17/04/2015	04/06/2015	Details
Morpholine, 4-C12-14-alkyl derivs.	800-906-3	1402434-48-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate	800-765-8	1424149-03-0	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
Aromatic hydrocarbons, C10-13, reaction products with branched nonene, sulfonated, sodium salts	800-660-7	1258274-08-6	Reproductive toxicity (pre-natal developmental toxicity)	23/01/2015	09/03/2015	Details
Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride	800-430-6	1419212-76-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	05/06/2014 05/06/2014	21/07/2014 21/07/2014	Details
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products	800-253-4	-	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Link to registration dossier not given as the dossier not yet disseminated.	30/11/2015	14/01/2016	Details
Alcohols, C6-8, ethoxylated	800-182-9	1426148-68-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2)	800-038-5	1071838-81-7	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/01/2015	09/03/2015	Details
Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, magnesium salts, magnesium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50	701-469-0	-	Long-term toxicity to fish\|\|Note: testing proposed with Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 (EC no. 701-356-6)	04/09/2023	19/10/2023	Details
Reaction products of boric acid and calcium dihydroxide and lithium hydroxide	701-453-3	-	Genetic toxicity in vivo\|\|Note: testing proposed with diboron calcium tetraoxide (EC no. 237-224-5)	22/09/2022	07/11/2022	Details
Poly[oxy(methyl-1,2-ethanediyl)], .alapha.,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-[(1-oxo-2-propenyl)oxy	701-440-2	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine	701-437-6	-	Sub-chronic toxicity (90-day): oral\|\| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2)	15/07/2022	29/08/2022	Details
Amino functional alkoxysilanes	701-410-9	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
Reaction products of [3-(2,3-epoxypropoxy)propyl]trimethoxysilane and triacetoxyvinylsilane	701-409-3	-	Genetic toxicity in vivo	25/01/2022	11/03/2022	Details
Amino functional alkoxysilanes	701-408-8	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1)	701-400-4	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Reaction products of amines, polyethylenepoly-, triethylenetetramine fraction and copper sulphate (1:1)	701-399-0	-	"Genetic toxicity in vivo \|\| Note: testing proposed with Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) (EC 701-400-4)"	25/11/2021	10/01/2022	Details
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol	701-393-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
Reaction products of 5,5-dimethylhydantoin and ethylene oxide	701-388-0	-	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Reaction products of diphenylamine with nonene, branched	701-385-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/04/2022	16/05/2022	Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate	701-363-4	-	Sub-chronic toxicity (90-day): oral	26/08/2021	11/10/2021	Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50	701-356-6	-	Long-term toxicity to fish	22/04/2021	07/06/2021	Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters	701-339-3	-	Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020	09/07/2020	Details
Platinum(IV) aqua hydroxo nitrato complexes	701-319-4	-	Genetic toxicity in vivo	25/05/2020	09/07/2020	Details
Platinum, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane complexes	701-315-2	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant.	25/05/2020	09/07/2020	Details
Alkenes, C6-11 (branched), hydroformylation products, distn. residues, heavy cracked fraction	701-314-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	31/01/2023	17/03/2023	Details
tri{[(2s)-1-ethoxy-1-oxopropan-2-yl]oxy}(vinyl)silane	701-301-6	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/05/2019 27/05/2019	11/07/2019 11/07/2019	Details
Propionaldehyde, reaction product with formaldehyde	701-281-9	-	Genetic toxicity in vivo \|\| Note: the EC/list number of the substance has been changed.	10/12/2018	24/01/2019	Details
benzyl butyl cis-cyclohexane-1,2-dicarboxylate	701-279-8	1931129-39-3	Long-term toxicity to fish \|\| Note: Link to the registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Sub-chronic toxicity (90-day): oral \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5	10/12/2018 10/12/2018 10/12/2018	24/01/2019 24/01/2019 24/01/2019	Details
C14-17 alkanes, sec-mono- and disulfonic acids, phenyl esters	701-257-8	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Sulfonic acids, C10-C21-alkane, Ph-esters (EC 293-728-5)	10/08/2018	24/09/2018	Details
Soybean oil, oligomerized	701-252-0	-	Reproductive toxicity (pre-natal developmental toxicity)	06/09/2018	22/10/2018	Details
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid	701-230-0	-	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Methanal, reaction products with 1,3-bis(aminomethyl)benzene and hydroxybenzen	701-207-5	1950616-36-0	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/05/2018 21/05/2018 21/05/2018	05/07/2018 05/07/2018 05/07/2018	Details
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide	701-196-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity)	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)	701-184-1	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
Octadecanoic acid, sulfonated, potassium salt	701-179-4	-	Sub-chronic toxicity (90-day): oral \|\| Note: The List number has changed.	31/01/2018	19/03/2018	Details
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine	701-177-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol	701-173-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1)	701-138-0	242482-67-3	Reproductive toxicity (pre-natal developmental toxicity)	01/09/2017	16/10/2017	Details
branched-nonyl 3,5,5 trimethylhexanoate	701-133-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: previous EC no 609-993-0	21/05/2018	05/07/2018	Details
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol	701-124-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol	701-122-3	106185-75-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine	701-120-2	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid	701-116-0	-	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid	701-116-0	84583-68-6	Sub-chronic toxicity (90-day): oral \|\| Note: The previous EC number for the substance is 283-219-6.	22/06/2017	07/08/2017	Details
Reaction products of orthoboric acid with 2,2'-iminodiethanol (1:1)	701-083-2	-	"Reproductive toxicity (pre-natal developmental toxicity) “\|\|Note: testing proposed with MEA Polyborate (EC 701-025-6)” Sub-chronic toxicity (90-day): oral “\|\|Note: testing proposed with MEA Polyborate (EC 701-025-6)”	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol	701-072-2	-	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no: 202-966-0)	16/06/2022	01/08/2022	Details
1,1'-methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol	701-041-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/06/2022 16/06/2022 16/06/2022	01/08/2022 01/08/2022 01/08/2022	Details
Propanol, oxybis-, polymer with 1,1'-methylenebis[4-isocyanatobenzene]	701-040-8	59952-43-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol	701-029-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
Reaction products of monoethanolamine and boric acid (1:1)	701-025-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Reaction products of monoethanolamine and boric acid (1:3) (EC 701-024-0)	27/01/2020 27/01/2020 27/01/2020	12/03/2020 12/03/2020 12/03/2020	Details
Reaction products of monoethanolamine and boric acid (1:3)	701-024-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020 27/01/2020	12/03/2020 12/03/2020 12/03/2020	Details
1,4-Cyclohexanedicarboxylic acid, 1,4-diisononyl ester	701-012-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/12/2018 10/12/2018	24/01/2019 24/01/2019	Details
Reaction Mass of Benzyl (1R,1S) 2,2,4-trimethyl-1-[(2-methylpropanoyl)oxy]pentan-3-yl benzene-1,2-dicarboxylate and Benzyl (3R,3S) 2,2,4-trimethyl-3-[(2-methylpropanoyl)oxy]pentyl benzene-1,2-dicarboxylate	701-008-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	27/05/2019	11/07/2019	Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes	700-992-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/02/2018 28/02/2018 28/02/2018	16/04/2018 16/04/2018 16/04/2018	Details
Reaction mass of 4-tert-butylphenyl diphenyl phosphate and bis(4-tert-butylphenyl) phenyl phosphate and triphenyl phosphate	700-990-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/09/2022	07/11/2022	Details
trisodium 2-(2-sulfoethoxy)ethane-1-sulfonate ethenesulfonate	700-978-5	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Note: testing proposed with Sodium ethylenesulphonate (EC No. 221-242-5)	03/05/2023	19/06/2023	Details
Alkenes, C20-24 alpha	700-962-8	-	Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with oct-1-ene (CAS RN 111-66-0)	22/10/2013 22/10/2013	05/12/2013 05/12/2013	Details
Reaction mass of (2-azaniumylethyl)[3-(trimethoxysilyl)propyl]amine chloride (2-azaniumylethyl)(benzyl)[3-(trimethoxysilyl)propyl]amine chloride 3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-10-ium chloride 10-benzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride 7,10-dibenzyl-3,3-dimethoxy-11-phenyl-2-oxa-7,10-diaza-3-silaundecan-7-ium chloride	700-961-2	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Reaction mass of butane-2,2-diyl dihydroperoxide and di-sec-butylhexaoxidane	700-954-4	1338-23-4	Sub-chronic toxicity (90-day): oral	19/12/2013	03/02/2014	Details
Alkane-alpha,omega-diyl bis{[(trimethoxysilyl)propyl]carbamate}_M2	700-904-1	1350725-68-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Methyl [3-(trimethoxysilyl) propyl]carbamate CAS 23432-62-4	02/11/2018	17/12/2018	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012 25/09/2012	12/11/2012 12/11/2012	Details
C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons	700-762-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance.	01/10/2018 01/10/2018 01/10/2018	15/11/2018 15/11/2018 15/11/2018	Details
Destillation fraction of chlorosilanes	700-717-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	16/05/2012 16/05/2012	02/07/2012 02/07/2012	Details
Trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide	700-597-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	18/06/2012 18/06/2012	02/08/2012 02/08/2012	Details
C20-C22 (even numbered, linear and branched) and C24 (branched) alkenes	700-497-0	-	Reproductive toxicity (two-generation reproductive toxicity and developmental toxicity) Sub-chronic toxicity (90-day): oral	19/11/2010 25/06/2012	03/01/2011 09/08/2012	Details
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol	700-427-9	-	Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	01/12/2010 01/12/2010 01/12/2010	17/01/2011 17/01/2011 17/01/2011	Details
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate	700-316-5	-	Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-days): oral	11/01/2011 11/01/2011	25/02/2011 25/02/2011	Details
Vinyl ethylene carbonate	700-261-7	4427-96-7	Sub-chronic toxicity (90-day): oral	30/06/2023	14/08/2023	Details
3,4-dihydroxy-1-[(Z)-octadec-9-enyl]pyrrolidine-2,5-dione	700-233-4	-	Bioaccumulation aquatic / sediment Long-term toxicity to fish Sub-chronic toxicity (90-day): oral	04/09/2023 04/09/2023 04/09/2023	19/10/2023 19/10/2023 19/10/2023	Details
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide	700-208-8	-	Sub-chronic toxicity (90-day): oral	04/10/2018	19/11/2018	Details
3-((5-(3-(Dodecanoyloxy)-2,2-dimethylpropylideneamino)-1,3,3-trimethylcyclohexyl)methylimino)-2,2-dimethylpropyl dodecanoate	700-071-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2012 16/05/2012	02/07/2012 02/07/2012	Details
2-{N-[2,6-Diamino-4-oxo-4H-pyrimidin-(5Z)-ylidene]-hydrazino}-5-methyl-benzenesulfonic acid	700-002-8	-	Reproductive toxicity (pre-natal developmental toxicity)	16/07/2012	30/08/2012	Details
hexahydrophthalic acid diglycidylester	696-026-0	1395383-69-3	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol	695-878-0	1283129-18-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
N,N,2,8-tetramethyl-5,11-dioxa-2,8-diazatridecan-13-amine	695-748-3	65286-55-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
Hexadecyldimethylamine	695-101-5	1275611-65-8	Reproductive toxicity (pre-natal developmental toxicity)	23/04/2018	07/06/2018	Details
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol	692-731-2	76950-43-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/02/2015 16/02/2015	02/04/2015 02/04/2015	Details
Lithium bis(fluorosulfonyl)imide	686-526-7	171611-11-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/10/2021 21/10/2021 21/10/2021	07/12/2021 07/12/2021 07/12/2021	Details
2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-α-D-glucopyranosyl bromide	686-241-8	81058-27-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
Lithium phosphorodifluoridate	643-080-8	24389-25-1	Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020	09/07/2020	Details
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate	642-902-2	163802-53-7	Genetic toxicity in vivo	10/03/2017	25/04/2017	Details
Alcohols, C18-22, distn. residues	641-136-6	1160164-88-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
Alcohols, C18-22, distn. residues	641-136-6	-	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011	29/08/2011 29/08/2011	Details
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid	641-088-6	-	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011 16/08/2011	30/09/2011 30/09/2011 30/09/2011	Details
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane	640-964-5	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
(E)-2-benzylideneoctanal	639-566-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/04/2011 15/04/2011	30/05/2011 30/05/2011	Details
Amides, Fatty acids C18 unsaturated, reaction products with tetraethylenepentamine	630-459-8	1225197-81-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids, C12-14 (even numbered), methyl ester	629-776-4	308065-15-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
N-[2-(piperazin-1-yl)ethyl]C18-unsatured-alkylamide	629-767-5	-	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011 15/07/2011	29/08/2011 29/08/2011 29/08/2011	Details
Fatty acids C18 unsat, reaction products with triethylenetetramine	629-765-4	1226892-44-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
potassium 4-cumenesulfonate	629-764-9	164524-02-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with sodium cumene sulphonate	22/06/2017 22/06/2017	07/08/2017 07/08/2017	Details
potassium 4-cumenesulfonate	629-764-9	164524-02-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9)	16/12/2016	30/01/2017	Details
potassium 4-isopropylbenzenesulphonate	629-764-9	164524-02-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
Fatty acids, C18 unsaturated, reaction product with ammonia-ethanolamine reaction by-products	629-757-0	1224966-15-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids C18 unsat, reaction products with polyethylene amines	629-742-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Amides, fatty acids C18 unsat, reaction products with polyethylene amines	629-735-0	1226892-50-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids C18 unsat, reaction products with Pentaethylenehexamine	629-732-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids C18 unsat, reaction products with tetraethylenepentamine	629-725-6	1226892-45-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
N-(C16-C18)alkyl(C16-C18)alkane-1-amine	629-721-4	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/06/2011 16/06/2011 16/06/2011	01/08/2011 01/08/2011 01/08/2011	Details
N,N,N`,N`,N``-Pentamethyl-N-C16-18 (even numbered) C18 unsat.-alkyl-1,3-propanediammonium chloride	629-716-7	1211950-04-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011	29/08/2011 29/08/2011	Details
Fatty acids, C18 unsat, reaction products with diethylenetriamine	629-715-1	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Fatty acids, C18-unsatd., reaction products with diethylenetriamine	629-715-1	1226892-43-8	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine	628-863-4	1219458-14-6	Reproductive toxicity (pre-natal developmental toxicity)	24/01/2019	11/03/2019	Details
N-(3-aminopropyl)-N'-C16-18 (evennumbered), C18 unsaturated alkyl -propane-1,3-diamine	628-863-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/07/2011 29/07/2011	12/09/2011 12/09/2011	Details

2 011 eredményből 201 - 400 megmutatása.

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