Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

951 - 1 000 / 2 011 tétel megjelenítése.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Tricyclodecanedimethanol	248-096-5	26896-48-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
N-ethyl-2-pyrrolidone (NEP)	220-250-6	2687-91-4	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route	26/01/2011 26/01/2011	14/03/2011 14/03/2011	Details
Diisopropylbenzene hydroperoxide	247-988-1	26762-93-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): dermal	15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day)	26/05/2010 26/05/2010 26/05/2010	12/07/2010 12/07/2010 12/07/2010	Details
tert-butyl peroxyneodecanoate	247-955-1	26748-41-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/06/2014 17/06/2014	01/08/2014 01/08/2014	Details
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate)	247-810-2	26566-95-0	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with another ZDDP category member to be determined based on outcome of other testing proposals Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate)	247-810-2	26566-95-0	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018	19/11/2018 19/11/2018	Details
Octanoic acid, monoester with glycerol	247-668-1	26402-26-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/10/2023 03/10/2023	17/11/2023 17/11/2023	Details
Dihexadecyl peroxodicarbonate	247-611-0	26322-14-5	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Name of the substance on which testing is proposed to be carried out: ditetradecyl peroxydicarbonate (EC: 258-436-4) Sub-chronic toxicity (90-day): oral	23/04/2018 23/04/2018	07/06/2018 07/06/2018	Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane	220-099-6	2627-95-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
1,3,5-tris[3-(trimethoxysilyl)propyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione	247-465-8	26115-70-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/10/2023 03/10/2023	17/11/2023 17/11/2023	Details
Bis(2-ethylhexyl) tetrabromophthalate	247-426-5	26040-51-7	Reproductive toxicity (pre-natal developmental toxicity)	16/05/2014	30/06/2014	Details
Orthoboric acid, compound with 2-aminoethanol	247-421-8	26038-87-9	Long-term or reproductive toxicity to birds Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011 15/09/2011 15/09/2011	31/10/2011 31/10/2011 31/10/2011	Details
Orthoboric acid, compound with 2-aminoethanol	247-421-8	26038-87-9	Repeated dose toxicity (90-day): oral	17/11/2011	02/01/2012	Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane	220-011-6	2602-34-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
Dimethyl 2,2'-azobis(2-methylpropionate)	219-976-6	2589-57-3	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine	426-040-2	25713-60-4	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/06/2011 16/06/2011 16/06/2011 16/06/2011	01/08/2011 01/08/2011 01/08/2011 01/08/2011	Details
4,4'-Methylenediphenyl diisocyanate, oligomers	500-040-3	25686-28-6	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate	247-161-5	25646-71-3	Genetic toxicity in vivo	17/06/2020	03/08/2020	Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane	219-863-1	2554-06-5	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014 03/03/2014 03/03/2014	17/04/2014 17/04/2014 17/04/2014 17/04/2014	Details
4-phenylbutan-2-one	219-847-4	2550-26-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons	22/11/2017	08/01/2018	Details
Triethoxypropylsilane	219-842-7	2550-02-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
Dodecene	246-922-9	25378-22-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	31/05/2011 31/05/2011	15/07/2011 15/07/2011	Details
Octene	246-920-8	25377-83-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with hex-1-ene Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Tridecene	246-919-2	25377-82-6	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	31/05/2011 31/05/2011	15/07/2011 15/07/2011	Details
2,2'-methylenediphenyl diisocyanate	219-799-4	2536-05-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	01/04/2022	16/05/2022	Details
Decene	246-870-7	25339-53-1	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011 25/06/2012	15/07/2011 15/07/2011 09/08/2012	Details
2,2'-(octadec-9-enylimino)bisethanol	246-807-3	25307-17-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017	16/10/2017	Details
2,2`-(octadec-9-enylimino)bisethanol	246-807-3	25307-17-9	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/07/2011 15/07/2011 15/07/2011	29/08/2011 29/08/2011 29/08/2011	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation	15/04/2011 15/04/2011	30/05/2011 30/05/2011	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019	10/06/2019	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	16/02/2015	02/04/2015	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction	08/03/2024 08/03/2024	22/04/2024 22/04/2024	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	01/08/2012	17/09/2012	Details
Tetrapropylenebenzene	246-772-4	25265-78-5	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol	246-771-9	25265-77-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/09/2022	07/11/2022	Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol	246-771-9	25265-77-4	Reproductive toxicity (pre-natal developmental toxicity)	16/06/2011	01/08/2011	Details
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol	246-771-9	25265-77-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/04/2019 26/04/2019 26/04/2019	10/06/2019 10/06/2019 10/06/2019	Details
Hexene	246-768-2	25264-93-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Hex-1-ene (EC 209-753-1) \|\| Note: testing proposed with Octadec-1-ene (EC 112-88-9) \|\| Note: testing proposed with Hexadecene (EC 248-131-4) \|\| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) \|\| Note: testing proposed with Nonene, branched (EC 306-492-6) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Hex-1-ene (EC 209-753-1) \|\| Note: testing proposed with Octadec-1-ene (EC 112-88-9) \|\| Note: testing proposed with Octadecene (EC 248-205-6) \|\| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) \|\| Note: testing proposed with Nonene, branched (EC 306-492-6)	23/11/2020 23/11/2020	07/01/2021 07/01/2021	Details
3-(trimethoxysilyl)propiononitrile	219-764-3	2526-62-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014	05/05/2014 05/05/2014	Details
Ethylenediamine, propoxylated	500-035-6	25214-63-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
Ethylenediamine, propoxylated	500-035-6	25214-63-5	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4) Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
2,4,4-trimethylpentene	246-690-9	25167-70-8	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: There are two testing proposals for this endpoint. Sub-chronic toxicity (90-day): oral	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
2,4,4-trimethylpentene	246-690-9	25167-70-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	15/07/2022	29/08/2022	Details

951 - 1 000 / 2 011 tétel megjelenítése.

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