Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

1 401 - 1 450 / 2 011 tétel megjelenítése.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
3-trimethoxysilylpropane-1-thiol	224-588-5	4420-74-0	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) \|\| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) \|\| Note: Testing proposal is based on concern identified by the registrant.	23/11/2020 23/11/2020	07/01/2021 07/01/2021	Details
4-morpholinecarbaldehyde	224-518-3	4394-85-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
4-morpholinecarbaldehyde	224-518-3	4394-85-8	Sub-chronic toxicity (90-day): oral	04/04/2014	19/05/2014	Details
2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2)	02/11/2018	17/12/2018	Details
Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8)	21/12/2021 21/12/2021 21/12/2021	04/02/2022 04/02/2022 04/02/2022	Details
zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category"	04/10/2018 04/10/2018 04/10/2018	19/11/2018 19/11/2018 19/11/2018	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/03/2023 01/03/2023 01/03/2023	17/04/2023 17/04/2023 17/04/2023	Details
methylsilanetriyl triacetate	224-221-9	4253-34-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0)	16/03/2015	30/04/2015	Details
methylsilanetriyl triacetate	224-221-9	4253-34-3	Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6)	03/10/2023	17/11/2023	Details
3,3'-oxybis(ethyleneoxy)bis(propylamine)	224-207-2	4246-51-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate	224-116-8	4203-89-8	Genetic toxicity in vivo	23/03/2020	07/05/2020	Details
2,2-dimethylpropane-1,3-diyl dibenzoate	224-081-9	4196-89-8	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate	223-989-2	4156-21-2	Sub-chronic toxicity (90-day): oral	29/04/2014	13/06/2014	Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate	223-989-2	4156-21-2	Reproductive toxicity (pre-natal developmental toxicity)	03/04/2023	22/05/2023	Details
Tris(p-isocyanatophenyl) thiophosphate	223-981-9	4151-51-3	6.1.2 Long-term toxicity to fish	08/03/2024	22/04/2024	Details
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide	223-829-1	4090-51-1	Sub-chronic toxicity (90-day): oral	16/06/2022	01/08/2022	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	28/02/2011 28/02/2011	14/04/2011 14/04/2011	Details
3,6,9,12-tetraazatetradecamethylenediamine	223-775-9	4067-16-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity)	22/11/2017 22/11/2017	08/01/2018 08/01/2018	Details
2,3-epoxypropyl isopropyl ether	223-672-9	4016-14-2	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
Nonane-1,9-diol	223-517-5	3937-56-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
Nonane-1,9-diol	223-517-5	3937-56-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	05/07/2018 05/07/2018	20/08/2018 20/08/2018	Details
Sodium chloroacetate	223-498-3	3926-62-3	Reproductive toxicity (pre-natal developmental toxicity)	14/10/2011	28/11/2011	Details
Sodium chloroacetate	223-498-3	3926-62-3	Reproductive toxicity (two-generation reproductive toxicity)	16/06/2011	01/08/2011	Details
Bumetrizole	223-445-4	3896-11-5	Bioaccumulation aquatic / sediment	18/06/2018	02/08/2018	Details
bis(3,5,5-trimethylhexanoyl) peroxide	223-356-0	3851-87-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Octa-1,7-diene	223-054-9	3710-30-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Diundecyl phthalate	222-884-9	3648-20-2	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Dioctyltin dilaurate	222-883-3	3648-18-8	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
1,3-bis(isocyanatomethyl)benzene	222-852-4	3634-83-1	6.1.2 Long-term toxicity to fish	08/03/2024	22/04/2024	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	14/02/2011	31/03/2011	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
1-butylpyrrolidin-2-one	222-437-8	3470-98-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/01/2022	11/03/2022	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	27/01/2020	12/03/2020	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/03/2015	30/04/2015	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Icos-1-ene	222-374-6	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	15/09/2011 15/09/2011	31/10/2011 31/10/2011	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
Bisisobutyryl peroxide	222-340-0	3437-84-1	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014 04/04/2014	19/05/2014 19/05/2014 19/05/2014	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	07/10/2016 07/10/2016	21/11/2016 21/11/2016	Details
sodium O,O-diethyl dithiophosphate \|\| Note: testing proposed with sodium O,O-diisobutyl dithiophosphate (EC 258-508-5)	222-079-2	3338-24-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
3,5,5-trimethylhexanoic acid	221-975-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/05/2011 31/05/2011	15/07/2011 15/07/2011	Details
Propylidynetrimethyl trimethacrylate	221-950-4	3290-92-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/04/2019	10/06/2019	Details
Propylidynetrimethyl trimethacrylate	221-950-4	3290-92-4	Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016	15/07/2016	Details
1,1,3,3-tetramethyldisiloxane	221-906-4	3277-26-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
Furan-2,5-dicarboxylic acid	221-800-8	3238-40-2	Reproductive toxicity (pre-natal developmental toxicity)	27/05/2019	11/07/2019	Details

1 401 - 1 450 / 2 011 tétel megjelenítése.

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