Korábbi/eredmények

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

1 351 - 1 400 / 2 011 tétel megjelenítése.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2011	15/08/2011	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	Bioaccumulation aquatic / sediment	25/06/2019	09/08/2019	Details
N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine	229-761-9	6711-48-4	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with N,N-diethylpropane-1,3-diamine (EC no. 203-236-4)	22/09/2022	07/11/2022	Details
1,8-diazabicyclo[5.4.0]undec-7-ene	229-713-7	6674-22-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
4-methylthiosemicarbazide	229-563-2	6610-29-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014	03/11/2014 03/11/2014	Details
3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane	229-542-8	6600-31-3	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt	229-390-2	6505-30-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	23/11/2020	07/01/2021	Details
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate	229-208-1	6428-31-5	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
1,1`-(1,1-dimethyl-3-methylene-1,3-propanediyl)bisbenzene	228-846-8	6362-80-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Sodium hydrogen-5-sulphoisophthalate	228-845-2	6362-79-4	Genetic toxicity in vivo	29/04/2014	13/06/2014	Details
Sodium hydrogen-5-sulphoisophthalate	228-845-2	6362-79-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	228-768-4	6358-31-2	7.5.2 Repeated dose toxicity: inhalation	08/03/2024	22/04/2024	Details
Hexyl salicylate	228-408-6	6259-76-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4)	25/05/2020	09/07/2020	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9) Sub-chronic toxicity (90 day): inhalation \|\| Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)	04/10/2013 04/10/2013	18/11/2013 18/11/2013	Details
2,4,6,8,10-pentamethylcyclopentasiloxane	228-204-7	6166-86-5	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
(R)-p-mentha-1,8-diene	227-813-5	5989-27-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/05/2020	09/07/2020	Details
trichloro(hexadecyl)silane	227-575-2	5894-60-0	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6) Sub-chronic toxicity (90-day): oral Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N,N'-hexane-1,6-diylbis(hexahydro-2-oxo-1H-azepine-1-carboxamide)	227-563-7	5888-87-9	Genetic toxicity in vivo	18/09/2014	03/11/2014	Details
o-(p-isocyanatobenzyl)phenyl isocyanate	227-534-9	5873-54-1	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
1,1,3,3-tetramethylbutyl hydroperoxide	227-369-2	5809-08-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
dichlorocyclohexylmethylsilane	226-956-0	5578-42-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0)	16/03/2015	30/04/2015	Details
2-ethylhexyl benzoate	226-641-8	5444-75-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
Guanidinium phosphate (1:1)	226-551-9	5423-22-3	Sub-chronic toxicity (90-day): oral	16/05/2014	30/06/2014	Details
Citral	226-394-6	5392-40-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	28/02/2018	16/04/2018	Details
4,4'-methylenedi-2,6-xylenol	226-378-9	5384-21-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	03/04/2023	22/05/2023	Details
Pentane-1,2-diol	226-285-3	5343-92-0	Sub-chronic toxicity (90-day): oral	16/06/2011	01/08/2011	Details
2-Octyldodecan-1-ol	226-242-9	5333-42-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
Sulphamidic acid	226-218-8	5329-14-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with ammonium sulphamate (pH consideration)	23/04/2018	07/06/2018	Details
Sulphamidic acid	226-218-8	5329-14-6	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	14/02/2011 14/02/2011 14/02/2011	31/03/2011 31/03/2011 31/03/2011	Details
Sulphamidic acid	226-218-8	5329-14-6	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
4,4'-methylenebis[N-sec-butylaniline]	226-122-6	5285-60-9	Bioaccumulation aquatic / sediment	27/01/2020	12/03/2020	Details
octyltrichlorosilane	226-112-1	5283-66-9	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3)	25/06/2015	10/08/2015	Details
4-[3-(1-naphthylamino)propyl]morpholine	226-033-2	5235-82-5	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
Etocrilene	226-029-0	5232-99-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	24/02/2020 24/02/2020	09/04/2020 09/04/2020	Details
N-[3-(dimethylamino)propyl]methacrylamide	226-002-3	5205-93-6	Reproductive toxicity (pre-natal developmental toxicity)	29/04/2011	14/06/2011	Details
5-ethyl-1,3-dioxane-5-methanol	225-967-8	5187-23-5	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	03/10/2023 03/10/2023 03/10/2023	17/11/2023 17/11/2023 17/11/2023	Details
5-ethyl-1,3-dioxane-5-methanol	225-967-8	5187-23-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2014 31/01/2014	17/03/2014 17/03/2014	Details
(3-chloropropyl)triethoxysilane	225-805-6	5089-70-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
N-isopropylhydroxylamine	225-791-1	5080-22-8	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014 18/02/2014	04/04/2014 04/04/2014 04/04/2014	Details
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline	225-716-2	5026-74-4	Genetic toxicity in vivo \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline	225-716-2	5026-74-4	Genetic toxicity in vivo \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
N-(3-aminopropyl)iminodiethanol	225-642-0	4985-85-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	14/08/2014 14/08/2014	28/09/2014 28/09/2014	Details
2,2-bis(hydroxymethyl)propionic acid // 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid	225-306-3	-	Reproductive toxicity (pre-natal developmental toxicity study) Sub-chronic oral toxicity (90-day): oral	05/04/2011 05/04/2011	20/05/2011 20/05/2011	Details
Octylphosphonic acid	225-218-5	4724-48-5	Reproductive toxicity (pre-natal developmental toxicity)	16/05/2014	30/06/2014	Details
Octylphosphonic acid	225-218-5	4724-48-5	Sub-chronic toxicity (90-day): oral	03/04/2023	22/05/2023	Details
2,2'-(cyclohexylimino)bisethanol	224-809-5	4500-29-2	Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019	01/11/2019	Details
3-methylpentane-1,5-diol	224-709-1	4457-71-0	Long-term toxicity to fish	01/03/2023	17/04/2023	Details
3-trimethoxysilylpropane-1-thiol	224-588-5	4420-74-0	Long-term toxicity to fish\|\|Note: testing proposed with 3-Triethoxysilylpropane-1-thiol (EC no. 238-883-1)	22/09/2022	07/11/2022	Details

1 351 - 1 400 / 2 011 tétel megjelenítése.

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