Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1,151 - 1,200 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
1,2-dimethylimidazole	217-101-2	1739-84-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters	946-149-3	1571954-81-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/05/2018 21/05/2018	05/07/2018 05/07/2018	Details
2,2-dimethyl-1,3-dioxolan-4-ylmethanol	202-888-7	100-79-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
3-(trimethoxysilyl)propylamine	237-511-5	13822-56-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
3-aminopropyltriethoxysilane	213-048-4	919-30-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane	260-350-7	56706-10-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	23/04/2018 23/04/2018	07/06/2018 07/06/2018	Details
4-hydroxy-4-methylpentan-2-one	204-626-7	123-42-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/09/2016 01/09/2016	17/10/2016 17/10/2016	Details
4-morpholinecarbaldehyde	224-518-3	4394-85-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
8,9,10-trinorborn-2-ene	207-866-0	498-66-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/11/2015 01/11/2015	16/12/2015 16/12/2015	Details
Amides, C16-C18 (even) , N,N'-ethylenebis	931-299-4	68390-94-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/03/2023 01/03/2023	17/04/2023 17/04/2023	Details
Amines, polyethylenepoly-, triethylenetetramine fraction	292-588-2	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/11/2017 22/11/2017	08/01/2018 08/01/2018	Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched	292-588-2	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
Ashes (residues), plant	297-049-5	93333-79-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
ASPHALT	232-490-9	8052-42-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	31/05/2016 31/05/2016	15/07/2016 15/07/2016	Details
barium titanium trioxide	234-975-0	12047-27-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
Benzene, diethenyl- and Benzene, ethenylethyl-	910-757-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/08/2019 16/08/2019	30/09/2019 30/09/2019	Details
Biphenyl-4,4'-diol	202-200-5	92-88-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
Chloroethane	200-830-5	75-00-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	10/03/2017 10/03/2017	25/04/2017 25/04/2017	Details
cobalt dichloride	231-589-4	7646-79-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/07/2016 18/07/2016	01/09/2016 01/09/2016	Details
Ditolyl ether	248-948-6	28299-41-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021 21/10/2021	07/12/2021 07/12/2021	Details
Docosan-1-ol	211-546-6	661-19-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/06/2023 30/06/2023	14/08/2023 14/08/2023	Details
dodecamethylpentasiloxane	205-492-2	141-63-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	17/06/2020 17/06/2020	03/08/2020 03/08/2020	Details
Ethylene	200-815-3	74-85-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Ethylenediamine, propoxylated	500-035-6	25214-63-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
hexadecyltrimethoxysilane	240-464-3	16415-12-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021 25/11/2021	10/01/2022 10/01/2022	Details
Hexamethylcyclotrisiloxane	208-765-4	541-05-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
Hexan-6-olide	207-938-1	502-44-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate	252-029-5	34443-12-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/01/2021 21/01/2021	08/03/2021 08/03/2021	Details
pentaerythritol	204-104-9	115-77-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	20/12/2017 20/12/2017	05/02/2018 05/02/2018	Details
Peracetic acid	201-186-8	79-21-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Phthalic anhydride	201-607-5	85-44-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol	911-819-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	16/08/2019 16/08/2019	30/09/2019 30/09/2019	Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene	939-009-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen	939-489-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid	931-291-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020 23/03/2020	07/05/2020 07/05/2020	Details
Sodium metavanadate	237-272-7	13718-26-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/01/2022 25/01/2022	11/03/2022 11/03/2022	Details
tert-dodecanethiol	246-619-1	25103-58-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/06/2017 22/06/2017	07/08/2017 07/08/2017	Details
tetrahydro-2-methylfuran	202-507-4	96-47-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	27/01/2020 27/01/2020	12/03/2020 12/03/2020	Details
Tris(2-butoxyethyl) phosphate	201-122-9	78-51-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate	250-418-4	30989-05-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	29/04/2016 29/04/2016	13/06/2016 13/06/2016	Details
undec-10-enoic acid	203-965-8	112-38-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate	940-272-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017 01/09/2017	16/10/2017 16/10/2017 16/10/2017	Details
Zinc, O,O-mixed (iso-Bu), (iso-Pr), (pentyl) phosphorodithioate	820-225-5	101747-77-7	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity) “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0) Sub-chronic toxicity (90-day): oral “\|\| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)	26/04/2019 26/04/2019 26/04/2019	10/06/2019 10/06/2019 10/06/2019	Details
Reaction mass of diisobutyl adipate and diisobutyl glutarate and diisobutyl succinate	907-870-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\|Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 ) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Reaction mass of dimethyl adipate and dimethyl glutarate and dimethyl succinate (EC 906-170-0 )	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
2,2,4,4,6,8,8-heptamethylnonane	224-506-8	4390-04-9	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with two substances in a grouping approach: Icosane (EC 204-015-1) and Hydrocarbons, C14-C19, iso-alkanes, cyclics; aromatics <2% (920-114-2)	02/11/2018	17/12/2018	Details
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics	917-828-1	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with two substances in a group: Icosane (EC 204-018-1) and Hydrocarbons, C14-C19, isoalkanes, cyclics, < 2% aromatics (920-114-2)	02/11/2018	17/12/2018	Details

Showing 1,151 - 1,200 of 2,011 results.

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