Προηγούμενες/Αποτελέσματα

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Εμφάνιση 501 - 600 από 2.011 αποτελέσματα.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Ethane- 1,2-diol, propoxylated	500-078-0	31923-84-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	05/07/2018 05/07/2018 05/07/2018	20/08/2018 20/08/2018 20/08/2018	Details
4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane	500-070-7	30583-72-3	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014 17/07/2014	Details
Tetrakis(hydroxymethyl)phosphonium chloride, oligomeric reaction products with urea	500-057-6	27104-30-9	Sub-chronic toxicity (90-day): oral	02/09/2011	17/10/2011	Details
Propylidynetrimethanol, propoxylated	500-041-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with analogue substance Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with analogue substance Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with analogue substance	05/07/2018 05/07/2018 05/07/2018	20/08/2018 20/08/2018 20/08/2018	Details
4,4'-Methylenediphenyl diisocyanate, oligomers	500-040-3	25686-28-6	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0)	16/06/2022	01/08/2022	Details
Ethylenediamine, propoxylated	500-035-6	25214-63-5	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with 1,1',1'',1'''-ethylenedinitrilotetrapropan-2-ol (EC no. 203-041-4) Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
Ethylenediamine, propoxylated	500-035-6	25214-63-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/04/2019 26/04/2019	10/06/2019 10/06/2019	Details
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated	500-022-5	9014-85-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) \|\|	25/11/2019	09/01/2020	Details
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy-	500-012-0	9004-77-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1). Reproductive toxicity (pre-natal developmental toxicity) – rabbits \|\| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) Reproductive toxicity (pre-natal developmental toxicity) – rats- \|\| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)	27/01/2020 27/01/2020 27/01/2020	12/03/2020 12/03/2020 12/03/2020	Details
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene)	500-004-7	9003-29-6	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol	485-270-1	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022 28/11/2022	12/01/2023 12/01/2023 12/01/2023	Details
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol	485-270-1	-	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl-	485-230-3	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	28/11/2022 28/11/2022	12/01/2023 12/01/2023	Details
(E)-N-(pentan-2-ylidene)hydroxylamine	484-470-6	623-40-5	Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021	03/05/2021	Details
N-pentan-2-ylidenehydroxylamine	484-470-6	623-40-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
Pentaerythritol, reaction product with fatty acids, C8 to 18 (even numbered) and/or branched and/or unsaturated	484-420-3	-	Reproductive toxicity (pre-natal developmental toxicity)	30/04/2012	14/06/2012	Details
Reaction products of Fatty acids, C16-18 and C18-unsatd. and reaction mass of 1,3-alkanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-heteromonocycle-5,5-dimethanol	484-360-8	98859-60-0	Reproductive toxicity (pre-natal developmental toxicity)	17/08/2012	01/10/2012	Details
Everzol Red CDN Crude	483-940-8	-	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	31/01/2018	19/03/2018	Details
4-fluoro-1,3-dioxolan-2-one	483-360-5	114435-02-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	24/07/2019	09/09/2019	Details
3-amino-4-octanol	482-070-6	1001354-72-8	Reproductive toxicity (developmental toxicity)	19/11/2010	03/01/2011	Details
1,3- and 1,4-cyclohexandicarboxyaldehyde	482-020-3	-	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2014	29/08/2014	Details
C8-C26 branched and linear hydrocarbons - Distillates	481-740-5	848301-67-7	Bioaccumulation aquatic / sediment	11/05/2010	25/06/2010	Details
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt	480-890-9	906532-68-1	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	18/11/2014	02/01/2015	Details
1-chloro-2,3-dimethylbenzene	480-880-4	608-23-1	Reproductive toxicity (pre-natal developmental toxicity)	10/08/2018	24/09/2018	Details
4-((Triethoxysilyl)methyl) morpholine	480-370-1	21743-27-1	Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day)	27/11/2009 27/11/2009 27/11/2009	11/01/2010 11/01/2010 11/01/2010	Details
1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane	479-930-8	613222-52-9	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
N-(2-nitrophenyl)phosphoric triamide	477-690-9	-	Long-term toxicity to fish	18/03/2021	03/05/2021	Details
LiFePO4	476-700-9	-	Reproductive toxicity (pre-natal developmental toxicity)	22/10/2013	05/12/2013	Details
Reaction product Formaldehyde, amine and phenol	476-290-1	-	Genetic toxicity in vivo	15/08/2013	30/09/2013	Details
tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate	474-870-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/09/2019 17/09/2019	01/11/2019 01/11/2019	Details
Reaction mass of 1-(1-Methyl-2-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-2-ol and 1-(2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)propoxy)-propan-2-ol and 2-(2-(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yloxy]-propoxy)-propan-1-ol and 2-(1-Methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yloxy)ethoxy)-propan-1-ol	470-680-5	958872-63-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-days): oral	21/01/2011 21/01/2011	07/03/2011 07/03/2011	Details
2,2-dimethyl-3-oxopropyl dodecanoate	468-880-2	102985-93-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester	468-880-2	102985-93-3	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Diphosphoric acid, compd. with piperazine (1:1)	457-330-7	66034-17-1	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	10/05/2022 10/05/2022 10/05/2022	27/06/2022 27/06/2022 27/06/2022	Details
Tetraammineplatinum (II) diacetate	457-310-8	-	Genetic toxicity in vivo (COMET, OECD TG 489) \|\| Note: Testing proposal is based on concern identified by the registrant. Testing proposed with Tetraammineplatinum dichloride (CAS 13933-32-9).	22/06/2017	07/08/2017	Details
5-Methoxy-2-tetralone	457-080-9	-	Genetic toxicity in vivo	06/09/2018	22/10/2018	Details
Lithium bis(oxalato)borate	456-990-3	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/05/2019 27/05/2019	11/07/2019 11/07/2019	Details
2-(2-Vinyloxyethoxy)ethyl acrylate	451-690-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	20/12/2017 20/12/2017	05/02/2018 05/02/2018	Details
2,4,7,9-tetramethyl-4,7-decanediol	451-160-7	17913-76-7	Long-term toxicity to fish "\|\| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019 17/09/2019	01/11/2019 01/11/2019	Details
Poly-(1,4-diisopropylbenzol)	449-400-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Ureidopropyltrialkoxysilane	449-160-7	116912-64-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction mass of trans-Cyclohexadecen-8-one, cis-Cyclohexadecen-8-one, trans-Cyclohexadecen-7-one, cis-Cyclohexadecen-7-one	448-300-4	88642-03-9	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant.	24/07/2019	09/09/2019	Details
Reaction mass of 1-[2-(2-aminobutoxy)ethoxy]but-2-ylamine and 1-({[2-(2-aminobutoxy)ethoxy]methyl}propoxy)but-2-ylamine	447-920-2	-	Reproductive toxicity (pre-natal developmental toxicity)	21/05/2018	05/07/2018	Details
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol	446-990-1	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/01/2015 23/01/2015	09/03/2015 09/03/2015	Details
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs.	445-790-1	-	Sub-chronic toxicity (90 day): inhalation	04/04/2014	19/05/2014	Details
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl	445-760-8	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/07/2015 31/07/2015	14/09/2015 14/09/2015	Details
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt	445-040-3	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate	443-860-6	302776-68-7	Long-term toxicity to fish	16/08/2011	30/09/2011	Details
Tetrasodium 2-(4-fluoro-6-(2-(2-sulfonatoethansulfonyl)ethylamino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(2-(2-hydroxy-5-sulfonatophenylazo)-4,5-dimethoxyphenylazo)-7-sulfonatonaphthalene-1-sulfonatocuprate(II)	442-640-7	479541-17-8	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
SUMILIZER GP	442-450-4	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Reaction mass of Benzeneacetic acid, alpha-oxo-, 1,1'-(oxydi-2,1-ethanediyl) ester and Benzeneacetic acid, alpha-oxo-, 2-(2-hydroxyethoxy)ethyl ester	442-300-8	-	Sub-chronic toxicity (90-day): oral	04/10/2013	18/11/2013	Details
reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate	442-300-8	-	Reproductive toxicity (pre-natal developmental toxicity)	15/01/2013	01/03/2013	Details
hexamolybdenum(3+) tris((dioctylcarbamothioyl)sulfanide) tris((ditridecylcarbamothioyl)sulfanide) hexahydrate hexasulfanediide	441-570-4	-	Bioaccumulation aquatic / sediment \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. Sub-chronic toxicity (90-day): oral \|\| Note: Link to registration dossier not given as the dossier not yet disseminated.	10/12/2018 10/12/2018 10/12/2018	24/01/2019 24/01/2019 24/01/2019	Details
1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?)	440-050-4	243857-97-8	Genetic toxicity in vivo	03/05/2023	19/06/2023	Details
Copper hydroxide nitrate	439-590-3	12158-75-7	Reproductive toxicity (pre-natal developmental toxicity)	03/11/2011	19/12/2011	Details
Alkane 6	438-390-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl )-3-pentanone	436-710-6	756-13-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
3-Pentanone, 1,1,1,2,2,4,5,5-nonafluoro-4-(trifluoromethyl )-	436-710-6	756-13-8	Reproductive toxicity (pre-natal developmental toxicity)	15/03/2011	29/04/2011	Details
S-(3-(triethoxysilyl)propyl)octanethioate	436-690-9	220727-26-4	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	25/09/2012 25/09/2012 25/09/2012	12/11/2012 12/11/2012 12/11/2012	Details
S-(3-(triethoxysilyl)propyl)octanethioate	436-690-9	220727-26-4	Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea	436-230-7	359406-89-6	Sub-chronic toxicity (90-day): oral	06/03/2012	20/04/2012	Details
Pentyl 2-cyano-(3-(6-methoxybenzothiazol-2-ylimino)-2,3-dihydro-1H-isoindol-1-ylidene)acetate	436-060-3	-	Genetic toxicity in vivo	26/10/2022	12/12/2022	Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide	435-860-1	214417-91-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide	435-860-1	214417-91-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/04/2012 17/04/2012	01/06/2012 01/06/2012	Details
Polyamide wax	434-430-9	-	Long-term toxicity to fish	07/07/2020	21/08/2020	Details
Reaction products of polyaminoalkane and substituted octadecanoic acid	434-430-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2016 16/12/2016	30/01/2017 30/01/2016	Details
3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid	434-070-2	-	Sub-chronic toxicity (90-day): oral	18/02/2013	04/04/2013	Details
ethyl methyl carbonate	433-480-9	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with an analogue substance.	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane	433-260-2	168253-59-6	Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral	06/09/2010 06/09/2010	20/10/2010 20/10/2010	Details
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine	432-840-2	220926-97-6	Repeated dose toxicity: Inhalation	04/05/2010	18/06/2010	Details
tetrasodium 2-(4-fluoro-6-(methyl-(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatophenylazo)naphthalene-1,7-disulfonate	432-550-6	243858-01-7	Genetic toxicity in vivo	30/06/2023	14/08/2023	Details
platinum(IV) nitrate/nitric acid solution	432-400-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
potassium titanium oxide (K2Ti6O13)	432-240-0	12056-51-8	Long-term toxicity to fish	17/05/2017	03/07/2017	Details
1-methyl-4-(methylsulfonyl)-2-nitrobenzene	430-550-0	1671-49-4	Genetic toxicity in vivo	16/05/2011	30/06/2011	Details
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane	429-280-6	151900-44-6	Reproductive toxicity (developmental toxicity)	01/09/2010	15/10/2010	Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt	429-070-4	-	Sub-chronic toxicity (90-day): oral	22/04/2021	07/06/2021	Details
inorganic phosphorus salt	428-310-5	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
Inorganic phosphorus salt	428-310-5	-	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride	427-370-1	164288-56-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	03/04/2023	22/05/2023	Details
tetraammine platinum (II) hydrogen carbonate	426-730-3	123439-82-7	Genetic toxicity in vivo\|\| Note: Testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant.	25/10/2017	11/12/2017	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine	426-040-2	25713-60-4	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/06/2011 16/06/2011 16/06/2011 16/06/2011	01/08/2011 01/08/2011 01/08/2011 01/08/2011	Details
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate	425-220-8	5945-33-5	Sub-chronic toxicity (90-day): oral	01/09/2010	15/10/2010	Details
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate	425-220-8	5945-33-5	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide	423-340-5	162881-26-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	22/12/2010 22/12/2010 22/12/2010	07/02/2011 07/02/2011 07/02/2011	Details
2-(2H-Benzotriazol-2-yl)-6-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)phenol	422-600-5	73936-91-1	Bioaccumulation aquatic / sediment	01/04/2022	16/05/2022	Details
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives	421-820-9	192268-65-8	Long-term toxicity to fish\|\|Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9)	04/12/2023	18/01/2024	Details
reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives	421-820-9	192268-65-8	Reproductive toxicity (pre-natal developmental toxicity)	16/10/2014	01/12/2014	Details
1,2-diacetoxybut-3-ene	421-720-5	18085-02-4	Sub-chronic toxicity (90-day): oral	25/11/2021	10/01/2022	Details
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide	419-710-0	-	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	12/12/2014 12/12/2014 12/12/2014	26/01/2015 26/01/2015 26/01/2015	Details
4-(1-oxo-2-propenyl)-morpholine	418-140-1	5117-12-4	Genetic toxicity in vivo	21/09/2020	05/11/2020	Details
Reaction product of: polyethylene-polyamine-(C16-C18)-alkylamides with monothio-(C2)-alkyl phosphonates	417-450-2	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/06/2023 30/06/2023	14/08/2023 14/08/2023	Details
Branched hexatriacontane	417-070-7	-	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
A mixture of isomers of branched tetracosane	417-060-2	151006-61-0	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)	01/07/2021 01/07/2021 01/07/2021	16/08/2021 16/08/2021 16/08/2021	Details
Methylene-bis-4,1-(N-phenylene-N'-butylurea)	416-600-4	-	Bioaccumulation aquatic / sediment	17/05/2016	01/07/2016	Details
3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione	416-250-2	-	Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012	12/11/2012	Details
3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione	413-920-6	-	Reproductive toxicity (two-generation reproductive toxicity)	25/09/2012	12/11/2012	Details
3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate	413-910-1	95718-78-8	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/04/2012 17/04/2012 17/04/2012	01/06/2012 01/06/2012 01/06/2012	Details

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