Προηγούμενες/Αποτελέσματα

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Εμφάνιση 51 - 100 από 2.011 αποτελέσματα.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol	941-496-7	1689576-89-3	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0)	01/04/2022	16/05/2022	Details
Fatty acids, tall-oil, di- and triesters with trimethylolpropane	941-376-4	-	Long-term toxicity to aquatic invertebrates Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Testing proposed with EC No 931-531-4.	31/05/2016 31/05/2016 31/05/2016	15/07/2016 15/07/2016 15/07/2016	Details
3-methyldecane; benzene; cyclooctane; nonane	941-364-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	05/07/2018	20/08/2018	Details
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol)	941-357-0	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2019	05/12/2019	Details
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol	941-357-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	08/02/2017 08/02/2017	27/03/2017 27/03/2017	Details
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester	941-267-1	1445870-18-7	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2023 31/01/2023 31/01/2023	17/03/2023 17/03/2023 17/03/2023	Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated	941-216-3	-	Bioaccumulation aquatic / sediment \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue	941-212-1	-	Bioaccumulation aquatic / sediment \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).	15/07/2014 15/07/2014 15/07/2014 15/07/2014	29/08/2014 29/08/2014 29/08/2014 29/08/2014	Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate	941-152-6	-	Sub-chronic toxicity (90-day): oral\|\|Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2)	15/07/2022	29/08/2022	Details
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid	940-877-5	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	29/03/2019 29/03/2019	13/05/2019 13/05/2019	Details
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane	940-783-4	-	Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate	940-592-6	-	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
Fatty acids, tall oil and rosin reacted with maleic anhydride	940-281-5	-	Reproductive toxicity (pre-natal developmental toxicity) //Note:testing to be done with rosin maleated (CAS 8050-28-0) Sub-chronic toxicity (90-day): oral. //Note:testing to be done with rosin maleated (CAS 8050-28-0)	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate	940-272-6	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017 01/09/2017	16/10/2017 16/10/2017 16/10/2017	Details
Nonanoic acid (branched), 2-oxiranylmethyl ester	940-029-4	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Reproductive toxicity (two-generation reproductive toxicity) \|\| Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)	20/09/2013 20/09/2013 20/09/2013	04/11/2013 04/11/2013 04/11/2013	Details
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol	939-719-8	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate)	939-717-7	-	Sub-chronic toxicity (90-day): oral	02/06/2014	17/07/2014	Details
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate	939-702-5	-	Long-term toxicity to fish	25/11/2019	09/01/2020	Details
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate	939-702-5	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Ethoxylated bisphenol A diacrylate Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Ethoxylated bisphenol A diacrylate	12/12/2014 12/12/2014	26/01/2015 26/01/2015	Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture)	939-700-4	-	Sub-chronic toxicity (90-day): oral	21/10/2019	05/12/2019	Details
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts	939-691-7	-	Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019	01/11/2019	Details
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid	939-682-8	-	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt	939-650-3	-	Sub-chronic toxicity (90-day): oral	10/05/2022	27/06/2022	Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt	939-650-3	-	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
Distilled tall oil, magnesium salts	939-629-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics	939-601-6	-	Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics	02/06/2014	17/07/2014	Details
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate	939-595-5	-	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl	939-591-3	-	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2014	30/05/2014	Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide	939-581-9	-	Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018	11/05/2018	Details
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form	939-559-9	-	Reproductive toxicity (pre-natal developmental toxicity)	01/09/2017	16/10/2017	Details
Fatty acid chlorides, C18 unsatd., reaction products with sodium N-methyltaurinate	939-538-4	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014	19/05/2014 19/05/2014	Details
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt	939-513-8	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen	939-489-9	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen	939-489-9	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine	939-485-7	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide	939-459-5	-	Sub-chronic toxicity (90-day): oral	30/11/2015	14/01/2016	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts	939-457-4	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts	939-455-3	-	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral	18/09/2014 18/09/2014 18/09/2014	03/11/2014 03/11/2014 03/11/2014	Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1)	939-448-5	-	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-	02/06/2014 02/06/2014	17/07/2014 17/07/2014	Details
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran	939-429-1	16409-43-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Fatty acids, tall-oil, reaction products with acrylic acid	939-424-4	-	Long-term toxicity to fish	04/04/2014	19/05/2014	Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)-	939-401-9	1469983-41-2	Long-term toxicity to fish \|\|Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8)	15/07/2022	29/08/2022	Details
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts	939-382-7	-	Genetic toxicity in vivo	25/11/2021	10/01/2022	Details
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine	939-379-0	-	Reproductive toxicity (pre-natal developmental toxicity)	04/04/2014	19/05/2014	Details
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda	939-368-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	17/06/2014 17/06/2014	01/08/2014 01/08/2014	Details
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid	939-201-1	-	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol	939-071-6	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	02/07/2013 02/07/2013	16/08/2013 16/08/2013	Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene	939-009-8	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/09/2017 01/09/2017	16/10/2017 16/10/2017	Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene	939-009-8	-	Sub-chronic toxicity (90-day): oral	21/12/2021	04/02/2022	Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene	939-009-8	-	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details

Εμφάνιση 51 - 100 από 2.011 αποτελέσματα.

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