Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 27/01/2020 | 12/03/2020 | Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol | 701-029-8 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate | 229-934-9 | 6846-50-0 | Reproductive toxicity (pre-natal developmental toxicity) | 14/03/2016 | 28/04/2016 | Details | |
1-isopropyl-4-methylcyclohexane | 202-790-4 | 99-82-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
1-methyl-4-(methylsulfonyl)-2-nitrobenzene | 430-550-0 | 1671-49-4 | Genetic toxicity in vivo | 16/05/2011 | 30/06/2011 | Details | |
1-methylimidazole | 210-484-7 | 616-47-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine | 812-491-6 | 1312943-23-9 | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7) | 26/08/2021 | 11/10/2021 | Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-457-4 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-455-3 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts | 293-878-1 | 91648-19-0 |
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) |
18/06/2018 18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 02/08/2018 |
Details | |
1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. | 600-033-6 | 1001416-18-7 | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Reproductive toxicity (developmental toxicity) | 08/04/2010 | 24/05/2010 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine | 432-840-2 | 220926-97-6 | Repeated dose toxicity: Inhalation | 04/05/2010 | 18/06/2010 | Details | |
12-hydroxystearic acid | 203-366-1 | 106-14-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 17/11/2023 |
Details | |
14H-benz[4,5]isoquino[2,1-a]perimidin-14-one | 229-904-5 | 6829-22-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-nortall-oil alkyl derivs. | 263-171-2 | 61791-39-7 | Bioaccumulation aquatic / sediment | 16/05/2014 | 30/06/2014 | Details | |
2'-phenylacetohydrazide | 204-055-3 | 114-83-0 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-107-7 | 40039-93-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether | 926-564-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/10/2019 21/10/2019 |
05/12/2019 05/12/2019 |
Details | |
2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol | 620-540-6 | 1218787-32-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9 | 14/03/2016 | 28/04/2016 | Details | |
2,2'-(cyclohexylimino)bisethanol | 224-809-5 | 4500-29-2 | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
2,2'-(octadec-9-enylimino)bisethanol | 246-807-3 | 25307-17-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
2,2'-(octadecylimino)bisethanol | 233-520-3 | 10213-78-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(octadec-9-enylimino)bisethanol EC 246-807-3 | 16/12/2020 | 01/02/2021 | Details | |
2,2'-(octylimino)bisethanol | 239-555-0 | 15520-05-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/11/2019 25/11/2019 |
09/01/2020 09/01/2020 |
Details | |
2,2'-[(1-methylethylidene)bis(cyclohexane-4,1-diyloxymethylene)]bisoxirane | 236-502-3 | 13410-58-7 | Genetic toxicity in vivo | 22/04/2021 | 07/06/2021 | Details | |
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane | 618-939-5 | 933999-84-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Sub-chronic toxicity (90-day): oral | 30/09/2015 | 16/11/2015 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (developmental toxicity) | 26/01/2011 | 14/03/2011 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] | 245-509-0 | 23235-61-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2016 29/04/2016 |
13/06/2016 13/06/2016 |
Details | |
2,2'-azobis[2-methylbutyronitrile] | 236-740-8 | 13472-08-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 17/04/2014 |
Details | |
2,2'-azobis[2-methylpropionamidine] dihydrochloride | 221-070-0 | 2997-92-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] | 239-593-8 | 15545-97-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
2,2'-dimethyl-2,2'-azodipropiononitrile | 201-132-3 | 78-67-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 |
Details | |
2,2'-dimethyl-2,2'-azodipropiononitrile | 201-132-3 | 78-67-1 | Reproductive toxicity (pre-natal developmental toxicity) | 03/02/2016 | 21/03/2016 | Details | |
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) | 202-319-2 | 94-28-0 | Sub-chronic toxicity (90-day): oral | 26/01/2011 | 14/03/2011 | Details | |
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) | 202-319-2 | 94-28-0 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) | 202-319-2 | 94-28-0 | Reproductive toxicity (two-generation reproductive toxicity) | 18/09/2014 | 03/11/2014 | Details | |
2,2'-iminodi(ethylamine) | 203-865-4 | 111-40-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol | 212-985-6 | 901-44-0 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol | 212-985-6 | 901-44-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
2,2'-methylenediphenyl diisocyanate | 219-799-4 | 2536-05-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide | 223-829-1 | 4090-51-1 | Sub-chronic toxicity (90-day): oral | 16/06/2022 | 01/08/2022 | Details | |
2,2'-p-phenylenedioxydiethanol | 203-197-3 | 104-38-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
2,2,2',2'-Tetrakis(hydroxymethyl)-3,3'-oxydipropan-1-ol | 204-794-1 | 126-58-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/04/2022 | 16/05/2022 | Details | |
2,2,2`,2`-Tetrakis(hydroxymethyl)-3,3`-oxydipropan-1-ol | 204-794-1 | 126-58-9 | Reproductive toxicity (pre-natal developmental toxicity) | 15/03/2011 | 29/04/2011 | Details | |
2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate | 915-277-1 | 32052-51-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |