Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol | 221-573-5 | 3147-75-9 | Bioaccumulation aquatic / sediment | 15/07/2014 | 29/08/2014 | Details | |
2-methoxyethyl acrylate | 221-499-3 | 3121-61-7 | Genetic toxicity in vivo | 21/03/2014 | 05/05/2014 | Details | |
p-tert-butylphenyl 1-(2,3-epoxy)propyl ether | 221-453-2 | 3101-60-8 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2014 17/06/2014 17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 01/08/2014 01/08/2014 |
Details | |
Trimethoxyoctylsilane | 221-338-7 | 3069-40-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
trimethoxyoctylsilane | 221-338-7 | 3069-40-7 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) | 07/08/2015 | 22/09/2015 | Details | |
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine | 221-336-6 | 3069-29-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Sub-chronic toxicity (90-day): oral
Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Tetra(isobutyl)thioperoxydicarbamic acid | 221-312-5 | 3064-73-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 |
Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) | 221-220-5 | 3033-62-3 |
7.8.1 Toxicity to reproduction 7.8.2 Developmental toxicity / teratogenicity |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
hex-3-yne-2,5-diol | 221-209-5 | 3031-66-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
bis(2-dimethylaminoethyl)(methyl)amine | 221-201-1 | 3030-47-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
Cyclohexylidenebis[tert-butyl] peroxide | 221-111-2 | 3006-86-8 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
tert-butyl 2-ethylperoxyhexanoate | 221-110-7 | 3006-82-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 30/05/2011 |
Details | |
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide | 221-088-9 | 3001-98-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
2,2'-azobis[2-methylpropionamidine] dihydrochloride | 221-070-0 | 2997-92-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 |
Details | |
Trimethoxyphenylsilane | 221-066-9 | 2996-92-1 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 | Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) | 17/04/2015 | 04/06/2015 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane | 220-780-8 | 2897-60-1 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 16/12/2016 | 30/01/2017 | Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2) |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
N-(1,1-dimethyl-3-oxobutyl)acrylamide | 220-713-2 | 2873-97-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form | 220-509-3 | 2786-76-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) | 03/10/2023 | 17/11/2023 | Details | |
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate | 220-482-8 | 2781-11-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
Allyl 3-cyclohexylpropionate | 220-292-5 | 2705-87-5 | Reproductive toxicity (pre-natal developmental toxicity) | 26/10/2022 | 12/12/2022 | Details | |
N-ethyl-2-pyrrolidone (NEP) | 220-250-6 | 2687-91-4 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) via the inhalatory route |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
1,1,3,3-tetramethyl-1,3-divinyldisiloxane | 220-099-6 | 2627-95-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
[3-(2,3-epoxypropoxy)propyl]triethoxysilane | 220-011-6 | 2602-34-8 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Dimethyl 2,2'-azobis(2-methylpropionate) | 219-976-6 | 2589-57-3 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 219-863-1 | 2554-06-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 17/04/2014 17/04/2014 |
Details | |
4-phenylbutan-2-one | 219-847-4 | 2550-26-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons | 22/11/2017 | 08/01/2018 | Details | |
Triethoxypropylsilane | 219-842-7 | 2550-02-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
2,2'-methylenediphenyl diisocyanate | 219-799-4 | 2536-05-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
3-chloropropyltrimethoxysilane | 219-787-9 | 2530-87-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 | Reproductive toxicity (pre-natal developmental toxicity) | 26/04/2019 | 10/06/2019 | Details | |
3-trimethoxysilylpropyl methacrylate | 219-785-8 | 2530-85-0 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): inhalation |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 |
6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction |
08/03/2024 08/03/2024 |
22/04/2024 22/04/2024 |
Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 01/08/2012 | 17/09/2012 | Details | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo | 16/02/2015 | 02/04/2015 | Details | |
3-(trimethoxysilyl)propiononitrile | 219-764-3 | 2526-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 |
Details | |
Strontium bis(2-ethylhexanoate) | 219-536-3 | 2457-02-5 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) | 23/11/2020 | 07/01/2021 | Details | |
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) | 219-514-3 | 2451-62-9 | Reproductive toxicity (two-generation reproductive toxicity) | 19/11/2010 | 03/01/2011 | Details | |
2-(2H-benzotriazol-2-yl)-p-cresol | 219-470-5 | 2440-22-4 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Reproductive toxicity (developmental toxicity) | 08/04/2010 | 24/05/2010 | Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) | 23/03/2020 | 07/05/2020 | Details | |
1,4-bis(2,3-epoxypropoxy)butane | 219-371-7 | 2425-79-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): most appropriate route |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |