Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether | 293-883-9 | 91648-24-7 | Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts | 293-878-1 | 91648-19-0 |
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) |
18/06/2018 18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 02/08/2018 |
Details | |
Rosin, reaction products with formaldehyde | 293-659-0 | 91081-53-7 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
Rosin, reaction products with formaldehyde | 293-659-0 | 91081-53-7 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Rosin (CAS RN 8050-09-7) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with _ Rosin (CAS RN 8050-09-7) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) |
19/07/2013 02/07/2013 02/07/2013 |
02/09/2013 16/08/2013 16/08/2013 |
Details | |
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction | 293-263-8 | 91053-01-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Fatty acids, C16-18, reaction products with diethanolamine | 293-014-3 | 91032-08-5 | Reproductive toxicity (pre-natal developmental toxicity) | 16/03/2015 | 30/04/2015 | Details | |
Fatty acids, C16-18, isononyl esters | 292-960-4 | 91031-57-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/06/2023 30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 14/08/2023 |
Details | |
Fatty acids, C16-18, barium salts | 292-883-6 | 91002-07-2 | Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2) | 04/04/2014 | 19/05/2014 | Details | |
Amines, polyethylenepoly-, triethylenetetramine fraction | 292-588-2 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
|
Details |
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched | 292-588-2 | 90640-66-7 | Reproductive toxicity (two-generation reproductive toxicity) | 05/04/2011 | 20/05/2011 | Details | |
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched | 292-588-2 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7) Reproductive toxicity (pre-natal developmental toxicity ) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/11/2015 | 16/12/2015 | Details | |
Alkanes, C12-26-branched and linear | 292-454-3 | 90622-53-0 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Alkenes, C13-14, hydroformylation products, distn. residues | 292-429-7 | 90622-29-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (EC 292-427-6) | 02/11/2018 | 17/12/2018 | Details | |
Alkenes, C13-14, hydroformylation products, distn. Residues | 292-429-7 | 90622-29-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Alkenes, C11-12, hydroformylation products, distn. Residues | 292-427-6 | 90622-27-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Alkenes, C11-12, hydroformylation products, distn. residues | 292-427-6 | 90622-27-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether | 291-813-1 | 90480-76-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts | 291-454-0 | 90411-76-0 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters | 290-754-9 | 90218-76-1 | Sub-chronic toxicity (90-day): oral | 29/07/2011 | 12/09/2011 | Details | |
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts | 288-917-4 | 85940-28-9 |
"Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) ""Testing proposed according to a plan for the ZDDP category.“
" Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts | 288-917-4 | 85940-28-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with a read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Fatty acids, tall-oil, compds. with oleylamine | 288-315-1 | 85711-55-3 | Long-term toxicity to fish | 04/04/2014 | 19/05/2014 | Details | |
Alkenes, C10-14 | 288-213-7 | 85681-75-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 25/06/2012 |
31/10/2011 31/10/2011 09/08/2012 |
Details | |
Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 |
Details | |
Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Isotridecan-1-ol (EC 248-469-2) | 16/12/2020 | 01/02/2021 | Details | |
Alkenes, C10-13 | 287-479-1 | 85535-87-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) | 287-476-5 | 85535-84-8 | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt | 286-344-4 | 85209-91-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol | 286-304-6 | 85204-10-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-[(4-methyl-3-sulphonatophenyl)sulphonyl]phenyl]azo]naphthalene-2-sulphonate | 286-122-7 | 85187-33-3 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 18/02/2021 | 05/04/2021 | Details | |
2-ethylhexanoic acid, monoester with propane-1,2-diol | 285-503-5 | 85114-00-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
Fatty acids, C16-18 and C18-unsatd., Et esters | 285-206-0 | 85049-36-1 | Long-term toxicity to fish | 01/07/2011 | 15/08/2011 | Details | |
Phosphoric acid, mixed esters with Bu alc. and ethylene glycol | 284-716-0 | 84962-20-9 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphoric acid, butyl ester; CAS No. 12788-93-1 |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene] | 284-366-9 | 84852-53-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 24/02/2020 | 09/04/2020 | Details | |
Star anise, Illicium verum, ext. | 283-518-1 | 84650-59-9 | Genetic toxicity in vivo | 22/04/2021 | 07/06/2021 | Details | |
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts | 283-392-8 | 84605-29-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another read-across member from ZDDP category Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts | 283-392-8 | 84605-29-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched | 283-219-6 | 84583-68-6 | Sub-chronic toxicity (90-day): oral | 12/04/2017 | 29/05/2017 | Details | |
Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate | 282-810-6 | 84434-11-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
1,3-Benzenediamine, coupled with diazotized m-phenylenediamine, acetates | 282-617-7 | 84281-74-3 | Genetic toxicity in vivo | 25/11/2021 | 10/01/2022 | Details | |
1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether | 282-199-6 | 84144-79-6 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 18/03/2021 | 03/05/2021 | Details | |
4-(1,1-dimethylethyl)cyclohexyl acrylate | 282-104-8 | 84100-23-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
Formaldehyde, reaction products with ethylenediamine | 281-928-5 | 84066-92-2 | Genetic toxicity in vivo | 16/05/2014 | 30/06/2014 | Details | |
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) | 281-018-8 | 83846-43-9 | Sub-chronic toxicity (90-day): oral | 18/06/2018 | 02/08/2018 | Details | |
Bis(2,4,4-trimethylpentyl)phosphinic acid | 280-445-7 | 83411-71-6 | Sub-chronic toxicity (90-day): oral | 18/03/2021 | 03/05/2021 | Details | |
Bis(2,4,4-trimethylpentyl)phosphinic acid | 280-445-7 | 83411-71-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2014 29/04/2014 |
13/06/2014 13/06/2014 |
Details | |
Bis(trimethoxysilylpropyl)amine | 280-084-5 | 82985-35-1 |
Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates | 279-632-6 | 80939-62-4 | Sub-chronic toxicity (90-day): oral | 23/11/2020 | 07/01/2021 | Details | |