Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts | 293-878-1 | 91648-19-0 |
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) |
18/06/2018 18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 02/08/2018 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-455-3 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-457-4 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine | 812-491-6 | 1312943-23-9 | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7) | 26/08/2021 | 11/10/2021 | Details | |
1-methylimidazole | 210-484-7 | 616-47-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
1-methyl-4-(methylsulfonyl)-2-nitrobenzene | 430-550-0 | 1671-49-4 | Genetic toxicity in vivo | 16/05/2011 | 30/06/2011 | Details | |
1-isopropyl-4-methylcyclohexane | 202-790-4 | 99-82-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
1-isopropyl-2,2-dimethyltrimethylene diisobutyrate | 229-934-9 | 6846-50-0 | Reproductive toxicity (pre-natal developmental toxicity) | 14/03/2016 | 28/04/2016 | Details | |
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol | 701-029-8 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
1-imino-1H-isoindol-3-amine | 222-426-8 | 3468-11-9 | Genetic toxicity in vivo | 27/01/2020 | 12/03/2020 | Details | |
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone | 216-475-4 | 1594-08-7 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues | 271-832-1 | 68609-68-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 29/08/2011 |
Details | |
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues | 271-832-1 | 68609-68-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
1-ethynylcyclohexanol | 201-100-9 | 78-27-3 | Sub-chronic toxicity (90-day): oral | 18/02/2014 | 04/04/2014 | Details | |
1-ethoxy-2-(2-methoxyethoxy)ethane | 213-690-5 | 1002-67-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 09/07/2020 |
Details | |
1-Dodecene, dimers | 814-509-8 | 62132-67-6 | Reproductive toxicity (pre-natal developmental toxicity) | 02/11/2018 | 17/12/2018 | Details | |
1-Dodecene, dimers | 814-509-8 | 62132-67-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 1-decene, homopolymer, hydrogenated (EC 500-183-1), 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-decene, dimer, unhydrogenated (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the Substance, 1-decene, homopolymer, hydrogenated (EC 500-183-1), and 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
18/03/2021 18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 03/05/2021 |
Details | |
1-Dodecene, dimer with 1-decene, hydrogenated | 604-766-2 | 151006-58-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
01/07/2021 01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 16/08/2021 |
Details | |
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine | 812-490-0 | 1312943-21-7 | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7) | 26/08/2021 | 11/10/2021 | Details | |
1-chloro-2,3-dimethylbenzene | 480-880-4 | 608-23-1 | Reproductive toxicity (pre-natal developmental toxicity) | 10/08/2018 | 24/09/2018 | Details | |
1-butylpyrrolidin-2-one | 222-437-8 | 3470-98-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/01/2022 | 11/03/2022 | Details | |
1-bromopropane (n-propyl bromide) | 203-445-0 | 106-94-5 | Genetic toxicity in vivo | 15/04/2011 | 30/05/2011 | Details | |
1-aminopropan-2-ol | 201-162-7 | 78-96-6 | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine | 411-930-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol | 266-587-2 | 67151-63-7 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol | 412-300-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 18/02/2021 | 05/04/2021 | Details | |
1-(vinyloxy)octadecane | 213-208-3 | 930-02-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE | 921-042-4 | - | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1-(2-hydroxyethyl)pyrrolidin-2-one | 222-359-4 | 3445-11-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
1,8-naphthylenediamine | 207-529-8 | 479-27-6 | Genetic toxicity in vivo | 22/04/2021 | 07/06/2021 | Details | |
1,8-diazabicyclo[5.4.0]undec-7-ene | 229-713-7 | 6674-22-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
1,7-Naphthalenedisulfonic acid, 2-[[4-chloro-6-(cyanoamino)-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-[2-methoxy-5-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-, lithium sodium salt (1:?:?) | 440-050-4 | 243857-97-8 | Genetic toxicity in vivo | 03/05/2023 | 19/06/2023 | Details | |
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 925-259-5 | 140921-24-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 411-700-4 | 140921-24-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane | 479-930-8 | 613222-52-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 |
Details | |
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane | 429-280-6 | 151900-44-6 | Reproductive toxicity (developmental toxicity) | 01/09/2010 | 15/10/2010 | Details | |
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether | 291-813-1 | 90480-76-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
1,5-Diisocyanatopentane | 807-040-5 | 4538-42-5 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane | 433-260-2 | 168253-59-6 |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2010 06/09/2010 |
20/10/2010 20/10/2010 |
Details | |
1,4-phenylenebis[(4-phenoxyphenyl)methanone] | 620-097-9 | 54299-17-1 | Bioaccumulation test in Fish, Reproductive toxicity (pre-natal developmental toxicity) | 24/02/2020 | 09/04/2020 | Details | |
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] | 620-097-9 | 54299-17-1 |
Bioaccumulation aquatic / sediment Long-term toxicity to fish |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
1,4-dimethylpiperazine | 203-412-0 | 106-58-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
1,4-diisopropylbenzene | 202-826-9 | 100-18-5 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS no. 99-62-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with CAS no. 99-62-7 |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1,4-diazabicyclooctane | 205-999-9 | 280-57-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
1,4-Cyclohexanedimethanol, reaction products with epichlorohydrin | 600-447-7 | 1035218-79-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated Sub-chronic toxicity (90 day): inhalation || Note: Link to registration dossier not given as the dossier not yet disseminated |
23/12/2015 23/12/2015 |
03/02/2016 03/02/2016 |
Details | |