Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
Προηγούμενες/Αποτελέσματα
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1,1'-[oxybis(ethyleneoxy)]diethylene | 212-133-3 | 764-99-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
triethoxy(phenyl)silane | 212-305-8 | 780-69-8 |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) |
25/06/2015 | 10/08/2015 | Details | |
bismuth citrate | 212-390-1 | 813-93-4 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4) Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4) |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Triethyl phosphonoacetate | 212-757-6 | 867-13-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Dec-1-ene | 212-819-2 | 872-05-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
Vinylene carbonate | 212-825-5 | 872-36-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/05/2021 20/05/2021 20/05/2021 |
05/07/2021 05/07/2021 05/07/2021 |
Details | |
Vinylene carbonate | 212-825-5 | 872-36-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/11/2021 | 10/01/2022 | Details | |
3,3,5-trimethylcyclohexan-1-one | 212-855-9 | 873-94-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol | 212-985-6 | 901-44-0 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol | 212-985-6 | 901-44-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone | 212-990-3 | 903-19-5 | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
Sodium 1-hydroxyethanesulphonate | 213-037-4 | 918-04-7 | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
3-aminopropyltriethoxysilane | 213-048-4 | 919-30-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
Dimethyl(propyl)amine | 213-139-9 | 926-63-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
tert-butyl peroxypivalate | 213-147-2 | 927-07-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
1-(vinyloxy)octadecane | 213-208-3 | 930-02-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
2-ethyl-4-methylimidazole | 213-234-5 | 931-36-2 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
N-phenylmaleimide | 213-382-0 | 941-69-5 | Genetic toxicity in vivo | 29/04/2011 | 14/06/2011 | Details | |
(1-hydroxycyclohexyl) (phenyl)methanone (hydroxycyclohexyl phenyl ketone) | 213-426-9 | 947-19-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2011 28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 14/04/2011 |
Details | |
Hydroxycyclohexyl phenyl ketone | 213-426-9 | 947-19-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/09/2019 | 01/11/2019 | Details | |
3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 213-485-0 | 957-68-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/08/2018 10/08/2018 10/08/2018 |
24/09/2018 24/09/2018 24/09/2018 |
Details | |
bis(piperidinothiocarbonyl) hexasulphide | 213-537-2 | 971-15-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2014 | 13/06/2014 | Details | |
bis(piperidinothiocarbonyl) hexasulphide | 213-537-2 | 971-15-3 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/02/2015 | 02/04/2015 | Details | |
Methylphosphonic acid | 213-607-2 | 993-13-5 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4) |
27/05/2019 27/05/2019 |
11/07/2019 11/07/2019 |
Details | |
1,1,1,3,3,3-hexamethyldisilazane | 213-668-5 | 999-97-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Hydroxytrimethylsilane (EC no. 213-914-1) |
16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 |
Details | |
1-ethoxy-2-(2-methoxyethoxy)ethane | 213-690-5 | 1002-67-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 09/07/2020 |
Details | |
1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 213-834-7 | 1025-15-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/09/2012 | 12/11/2012 | Details | |
Trimethoxypropylsilane | 213-926-7 | 1067-25-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 |
Details | |
tris(2-methoxyethoxy)vinylsilane | 213-934-0 | 1067-53-4 | Reproductive toxicity (pre-natal developmental toxicity) | 29/07/2011 | 12/09/2011 | Details | |
Adipohydrazide | 213-999-5 | 1071-93-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
Cyclohexane-1,4-dicarboxylic acid | 214-068-6 | 1076-97-7 | Reproductive toxicity (pre-natal developmental toxicity) | 27/11/2013 | 10/01/2014 | Details | |
dimethoxydimethylsilane | 214-189-4 | 1112-39-6 | Sub-chronic toxicity (90 day): inhalation | 16/10/2014 | 01/12/2014 | Details | |
dimethoxydimethylsilane | 214-189-4 | 1112-39-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
3-hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropionate | 214-222-2 | 1115-20-4 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 15/07/2011 |
Details | |
n-butyltin trichloride | 214-263-6 | 1118-46-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2011 | 14/06/2011 | Details | |
Undecane | 214-300-6 | 1120-21-4 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Tetradec-1-ene | 214-306-9 | 1120-36-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
N-butyl phenyl ether | 214-426-1 | 1126-79-0 | Long-term toxicity to fish | 03/04/2023 | 22/05/2023 | Details | |
4-hydroxybenzophenone | 214-507-1 | 1137-42-4 | Genetic toxicity in vivo | 18/02/2021 | 05/04/2021 | Details | |
Naphthalene-2,6-dicarboxylic acid | 214-527-0 | 1141-38-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/06/2022 | 01/08/2022 | Details | |
Trimethylamine, N-oxide | 214-675-6 | 1184-78-7 | Genetic toxicity in vivo||Note: testing proposed with Reference substance 001 [CAS No. 62637-93-8] | 06/06/2023 | 21/07/2023 | Details | |
Trimethoxy(methyl)silane | 214-685-0 | 1185-55-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity) |
12/04/2017 12/04/2017 |
29/05/2017 29/05/2017 |
Details | |
Trifluoro(trifluoromethoxy)ethylene | 214-703-7 | 1187-93-5 | Sub-chronic toxicity (90 day): inhalation | 29/04/2014 | 13/06/2014 | Details | |
4-chloroformylphthalic anhydride | 214-874-8 | 1204-28-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 27/01/2020 | 12/03/2020 | Details | |
α-methyl-1,3-benzodioxole-5-propionaldehyde | 214-881-6 | 1205-17-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
Dichlorobis(η-cyclopentadienyl)titanium | 215-035-9 | 1271-19-8 | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
Sodium xylenesulphonate | 215-090-9 | 1300-72-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2014 | 29/08/2014 | Details | |
Dibismuth trioxide | 215-134-7 | 1304-76-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |